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31. 发明授权

US2246519A Drift recorder 失效
公开(公告)号：US2246519A
公开(公告)日：1941-06-24
申请号：US26266639
申请日：1939-03-18
申请人： PHILIP JONES
发明人： PHILIP JONES
IPC分类号： E21B47/022
CPC分类号： E21B47/022

32. 发明授权

US12053916B1 Fishing lure injection molding using additive manufacturing 有权
公开(公告)号：US12053916B1
公开(公告)日：2024-08-06
申请号：US18216212
申请日：2023-06-29
申请人： Philip Jones
发明人： Philip Jones
IPC分类号： B29C33/38 , B29C45/14 , B29C45/17 , B29C45/32 , B29C45/58 , B33Y80/00 , A01K85/00 , B29K101/12 , B29L31/00
CPC分类号： B29C45/32 , B29C33/3842 , B29C45/14008 , B29C45/1742 , B29C45/58 , B33Y80/00 , A01K85/1897 , B29K2101/12 , B29L2031/7002
摘要： A molding device for producing thermoplastic articles and its method of use, wherein the molding device comprises a rigid bottom plate, a rigid top plate adapted to be removably coupled to the said bottom plate, a 3D-printed die or insert in the shape of half of the said article removably inserted into a CNC milled mold cavity. The molten thermoplastic material is injected in to the molding device through an injection port to form the thermoplastic in the shape of 3D-printed die or insert, wherein the thermoplastic article is a fishing lure.

33. 发明授权

US09479215B2 Processing digital samples in a wireless receiver 有权
标题翻译：在无线接收机中处理数字样本
公开(公告)号：US09479215B2
公开(公告)日：2016-10-25
申请号：US12016652
申请日：2008-01-18
申请人： Carlo Luschi , Simon Walker , Steve Allpress , Philip Jones
发明人： Carlo Luschi , Simon Walker , Steve Allpress , Philip Jones
IPC分类号： H04B1/707 , H04L25/02 , H04L25/03
CPC分类号： H04B1/707 , H04B2201/7071 , H04L25/0212 , H04L25/03012
摘要： A method of processing digital samples of a signal received at a receiver of a wireless communication system includes monitoring channel conditions and generating a channel indicator including at least one channel parameter by performing at least one of: estimating a channel mobility parameter and comparing it with a threshold; estimating a channel parameter of the energy of the channel outside a predefined temporal window, and comparing it with a threshold; estimating a channel temporal duration parameter and establishing if it meets predetermined criteria; estimating a channel-zero location parameter and establishing if it meets predetermined criteria; estimating a received-signal signal-to-disturbance power ratio, and comparing it to a threshold; estimating an estimated-channel-response signal-to-disturbance power ratio; estimating the degree of non-stationarity of the disturbance at the receiver input; and selecting one of a plurality of processing routines for processing the digital samples based on said channel indicator. Related receivers are also described.
摘要翻译：一种处理在无线通信系统的接收机处接收的信号的数字样本的方法包括监视信道状况并通过执行以下中的至少一个来生成包括至少一个信道参数的信道指示符：估计信道移动性参数并将其与阈; 估计在预定时间窗口之外的信道的能量的信道参数，并将其与阈值进行比较; 估计信道时间持续时间参数并确定它是否符合预定标准; 估计信道零位置参数并确定它是否符合预定标准; 估计接收信号信号与干扰功率比，并将其与阈值进行比较; 估计信道响应信号与干扰功率比; 估计接收机输入干扰的非平稳度; 以及基于所述信道指示符选择用于处理数字样本的多个处理例程之一。还描述了相关接收机。

34. 发明授权

US09274671B2 Managing a user interface for an application program 有权
标题翻译：管理应用程序的用户界面
公开(公告)号：US09274671B2
公开(公告)日：2016-03-01
申请号：US13820820
申请日：2011-08-23
申请人： Michael R. Croft , Philip Jones , Adam R. Rice , Matthew Whitbourne
发明人： Michael R. Croft , Philip Jones , Adam R. Rice , Matthew Whitbourne
IPC分类号： G06F3/0481 , G06F3/0482 , G06F9/44
CPC分类号： G06F3/0481 , G06F3/0482 , G06F9/453
摘要： A method, apparatus and computer program is disclosed for managing a user interface (UI) for an application program in which a plurality of user interface methods are provided for a given application program function, one or more of the more frequently used UI options being maintained in the UI while one or more of the less frequently used UI options are removed.
摘要翻译：公开了一种用于管理应用程序的用户界面（UI）的方法，装置和计算机程序，其中为给定的应用程序功能提供多个用户界面方法，一个或多个更频繁使用的UI选项被维护在UI中，而一个或多个不常用的UI选项被删除。

35. 发明授权

US08869167B2 Application hibernation 有权
标题翻译：应用程序休眠
公开(公告)号：US08869167B2
公开(公告)日：2014-10-21
申请号：US13420524
申请日：2012-03-14
申请人： Michael R. Croft , Philip Jones , Adam R. Rice , Matthew D. Whitbourne
发明人： Michael R. Croft , Philip Jones , Adam R. Rice , Matthew D. Whitbourne
IPC分类号： G06F9/46 , G06F9/445 , G06F9/48
CPC分类号： G06F8/4451 , G06F9/4451 , G06F9/485 , G06F2209/482
摘要： Operating a data processing system comprises defining a plurality of profiles, each profile comprising a list of one or more applications; receiving a defined user input requesting a switch from a first profile to a second profile; hibernating the (or each) application listed in the first profile; and recalling from hibernation the (or each) application listed in the second profile. Preferably, a graphical user interface is adjusted to reflect a change in status of each application that has been hibernated or recalled from hibernation.
摘要翻译：操作数据处理系统包括定义多个简档，每个简档包括一个或多个应用的列表; 接收将切换从第一简档请求到第二简档的定义的用户输入; 休眠第一个配置文件中列出的（或每个）应用程序; 并从休眠状态回忆第二个配置文件中列出的（或每个）应用程序。优选地，调整图形用户界面以反映已经从休眠状态休眠或召回的每个应用程序的状态的变化。

36. 发明授权

US08765760B2 [1,2,4] triazol [1,5-a] pyrazines useful as inhibitors of phosphodiesterases 有权
标题翻译： [1,2,4]三唑[1,5-a]吡嗪可用作磷酸二酯酶的抑制剂
公开(公告)号：US08765760B2
公开(公告)日：2014-07-01
申请号：US13347541
申请日：2012-01-10
申请人： John Emmerson Campbell , Philip Jones , Michael Charles Hewitt
发明人： John Emmerson Campbell , Philip Jones , Michael Charles Hewitt
IPC分类号： A61K31/495 , C07D457/00 , C07D471/00 , C07D495/00 , C07D497/00
CPC分类号： C07D519/00 , A61K31/4375 , A61K31/4745 , A61K31/4985 , A61K31/519 , A61K31/5383 , A61K45/06 , C07D471/04 , C07D487/04
摘要： Provided herein are compounds of formula (I): A-L-B (I) and pharmaceutically acceptable salts and stereoisomers thereof, wherein A is wherein X is (i) CR1 or N, or (ii) O or NR2, each Y is independently N or CR3, and each Z is independently N or C, wherein R1, R2 and R3 are defined in the specification; L is a linker, and B is a multicyclic ring; methods of their synthesis, pharmaceutical compositions comprising the compounds, and methods of their use. The compounds provided herein are inhibitors of phosphodiesterases and useful for the treatment, prevention, and/or management of various disorders, such as CNS disorders and metabolic disorders, e.g., neurological disorders, psychosis, schizophrenia, obesity and diabetes.
摘要翻译：本文提供式（I）的化合物：其中A是其中X是（i）CR 1或N，或（ii）O或NR 2，其中每个Y独立地是N或CR 3 并且每个Z独立地为N或C，其中R1，R2和R3在说明书中定义; L为连接体，B为多环; 其合成方法，包含该化合物的药物组合物及其使用方法。本文提供的化合物是磷酸二酯酶的抑制剂，并且可用于治疗，预防和/或治疗各种疾病，例如CNS障碍和代谢性疾病，例如神经障碍，精神病，精神分裂症，肥胖症和糖尿病。

37. 发明授权

US08604038B2 Pyrrolidine derived beta 3 adrenergic receptor agonists 有权
标题翻译：吡咯烷衍生的β3肾上腺素能受体激动剂
公开(公告)号：US08604038B2
公开(公告)日：2013-12-10
申请号：US13392282
申请日：2010-08-24
申请人： Scott D. Edmondson , Lehua Chang , Nam Fung Kar , Gergori J. Morriello , Christopher R. Moyes , Dong-Ming Shen , Cheng Zhu , Neville J. Anthony , Philip Jones , Graham F. Smith , Mark E. Scott , Christopher F. Thompson , Joon Jung , Carolyn Cammarano , Dawn Marie Hoffman
发明人： Scott D. Edmondson , Lehua Chang , Nam Fung Kar , Gergori J. Morriello , Christopher R. Moyes , Dong-Ming Shen , Cheng Zhu , Neville J. Anthony , Philip Jones , Graham F. Smith , Mark E. Scott , Christopher F. Thompson , Joon Jung , Carolyn Cammarano , Dawn Marie Hoffman
IPC分类号： A61K31/50 , A61K31/525
CPC分类号： C07D401/12 , C07D207/08 , C07D403/12 , C07D413/12 , C07D417/12 , C07D471/04
摘要： The present invention provides compounds of Formula (I), pharmaceutical compositions thereof, and method of using the same in the treatment or prevention of diseases mediated by the activation of β3-adrenoceptor.
摘要翻译：本发明提供式（I）的化合物，其药物组合物及其用于治疗或预防由β3肾上腺素受体激活介导的疾病的方法。

38. 发明申请

US20130267499A1 NOVEL TETRAHYDROPYRAZOLO [3,4-b] AZEPINE DERIVATIVES AND THEIR USE AS ALLOSTERIC MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS 有权
标题翻译：新型四氢呋喃并[3,4-b]亚胺衍生物及其作为代谢型谷氨酸受体的独立调节剂
公开(公告)号：US20130267499A1
公开(公告)日：2013-10-10
申请号：US13809581
申请日：2011-07-11
申请人： Christelle Bolea , Sylvain Celanire , Lam Tang , Nigel J. Liverton , Philip Jones
发明人： Christelle Bolea , Sylvain Celanire , Lam Tang , Nigel J. Liverton , Philip Jones
IPC分类号： C07D513/12 , A61K45/06 , A61K31/55
CPC分类号： C07D513/12 , A23L5/00 , A61B5/00 , A61K9/0019 , A61K9/0095 , A61K9/06 , A61K9/10 , A61K9/2059 , A61K31/429 , A61K31/433 , A61K31/4439 , A61K31/506 , A61K31/55 , A61K45/06 , C07D513/04 , C07D513/14 , A61K2300/00
摘要： The present invention relates to novel compounds of Formula (I), wherein M, A and Y are defined as in Formula (I); invention compounds are modulators of metabotropic glutamate receptors—subtype 4 (“mGluR4”) which are useful for the treatment or prevention of central nervous system disorders as well as other disorders modulated by mGluR4 receptors. The invention is also directed to pharmaceutical compositions and the use of such compounds in the manufacture of medicaments, as well as to the use of such compounds for the prevention and treatment of such diseases in which mGluR4 is involved.
摘要翻译：本发明涉及新的式（I）化合物，其中M，A和Y如式（I）所定义; 本发明化合物是代谢型谷氨酸受体的调节剂 - 亚型4（“mGluR4”），其可用于治疗或预防中枢神经系统疾病以及由mGluR4受体调节的其它障碍。本发明还涉及药物组合物和这些化合物在制备药物中的用途，以及这些化合物用于预防和治疗涉及mGluR4的疾病的用途。

39. 发明授权

US08470823B2 Saturated bicyclic heterocyclic derivatives as SMO antagonists 有权
标题翻译：饱和双环杂环衍生物作为SMO拮抗剂
公开(公告)号：US08470823B2
公开(公告)日：2013-06-25
申请号：US13060718
申请日：2009-08-28
申请人： Danila Branca , Federica Ferrigno , Jose Ignacio Martin Hernando , Philip Jones , Olaf Kinzel , Savina Malancona , Ester Muraglia , Maria Cecilia Palumbi , Giovanna Pescatore , Rita Scarpelli
发明人： Danila Branca , Federica Ferrigno , Jose Ignacio Martin Hernando , Philip Jones , Olaf Kinzel , Savina Malancona , Ester Muraglia , Maria Cecilia Palumbi , Giovanna Pescatore , Rita Scarpelli
IPC分类号： A61K31/4985
CPC分类号： C07D487/04
摘要： The present invention relates to compounds of formula I: and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smoantagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract.
摘要翻译：本发明涉及式I化合物及其药学上可接受的盐或互变异构体，其是Sonic Hedgehog途径的抑制剂，特别是Smoantagonists。因此，本发明的化合物可用于治疗与异常hedgehog途径活化相关的疾病，包括癌症，例如基底细胞癌，成神经管细胞瘤，前列腺，胰腺癌，乳腺癌，结肠癌，骨细胞和小细胞肺癌，以及癌症上胃肠道

40. 发明申请

US20130053396A1 PIPERIDINE AND PIPERAZINE DERIVATIVES AS SMO ANTAGONISTS 审中-公开
标题翻译：哌啶和哌嗪衍生物作为SMO拮抗剂
公开(公告)号：US20130053396A1
公开(公告)日：2013-02-28
申请号：US13496958
申请日：2010-09-21
申请人： Philip Jones , Jesus Maria Ontoria Ontoria
发明人： Philip Jones , Jesus Maria Ontoria Ontoria
IPC分类号： C07D417/14 , A61P35/02 , A61P35/00 , C07D413/14 , A61K31/496
CPC分类号： C07D413/04 , C07D417/04
摘要： The present invention relates to compounds of formula (I), and pharmaceutically acceptable salts or tautomers thereof which are inhibitors of the Sonic Hedgehog pathway, in particular Smo antagonists. Thus the compounds of this invention are useful for the treatment of diseases associated with abnormal hedgehog pathway activation, including cancer, for example basal cell carcinoma, medulloblastoma, prostate, pancreatic, breast, colon, bone and small cell lung cancers, and cancers of the upper GI tract.
摘要翻译：本发明涉及作为Sonic Hedgehog途径的抑制剂，特别是Smo拮抗剂的式（I）化合物及其药学上可接受的盐或互变异构体。因此，本发明的化合物可用于治疗与异常hedgehog途径活化相关的疾病，包括癌症，例如基底细胞癌，成神经管细胞瘤，前列腺，胰腺癌，乳腺癌，结肠癌，骨细胞和小细胞肺癌，以及癌症上胃肠道

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