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31. 发明申请

US20140200638A1 IMPLANTABLE MEDICAL DEVICE SWITCH MATRIX 有权
标题翻译：可移植医疗设备开关矩阵
公开(公告)号：US20140200638A1
公开(公告)日：2014-07-17
申请号：US13741205
申请日：2013-01-14
申请人： Eric Y. CHOW , David L. THOMPSON
发明人： Eric Y. CHOW , David L. THOMPSON
IPC分类号： A61N1/08
CPC分类号： A61N1/36125 , A61N1/05 , A61N1/08 , A61N1/14 , A61N1/36142 , A61N1/3718 , A61N1/3912
摘要： A particular implantable device includes one or more electrode connectors and multiple circuit elements within a housing. The implantable medical device may also include one or more switches, where each switch of the one or more switches is coupled between one or more of the multiple circuit elements and at least one electrode connector of the one or more electrode connectors.
摘要翻译：特定的可植入装置包括壳体内的一个或多个电极连接器和多个电路元件。可植入医疗装置还可以包括一个或多个开关，其中一个或多个开关的每个开关耦合在多个电路元件中的一个或多个以及一个或多个电极连接器的至少一个电极连接器中。

32. 发明授权

US08068911B2 System and method for regulating cardiopulmonary triggered therapy to the brain 有权
标题翻译：将心肺触发治疗调整到大脑的系统和方法
公开(公告)号：US08068911B2
公开(公告)日：2011-11-29
申请号：US11741109
申请日：2007-04-27
申请人： Jonathon E Giftakis , Nina M. Graves , David L Thompson
发明人： Jonathon E Giftakis , Nina M. Graves , David L Thompson
IPC分类号： A61N1/08
CPC分类号： A61B5/0476 , A61B5/0031 , A61B5/02 , A61B5/0245 , A61B5/0402 , A61B5/0452 , A61B5/0478 , A61B5/053 , A61B5/08 , A61B5/0816 , A61B5/1135 , A61B5/4094 , A61N1/05 , A61N1/3601 , A61N1/36082 , A61N1/36135 , A61N1/362 , A61N1/36521 , A61N1/36585 , A61N1/37 , A61N1/37247 , A61N1/37282 , A61N1/37288 , A61N1/3962
摘要： A medical device system includes a housing, the housing at least partially supporting a therapy module and a processor, and a respiratory monitoring element coupled to the processor. The processor is configured to activate the therapy module upon detection of a respiratory event in a respiratory signal. In some embodiments, the system may further comprise a brain monitoring element, and the processor may be configured to monitor a brain signal and change the therapeutic output based upon the brain signal.
摘要翻译：医疗装置系统包括壳体，壳体至少部分地支撑治疗模块和处理器，以及耦合到处理器的呼吸监测元件。处理器被配置为在检测到呼吸信号中的呼吸事件时激活治疗模块。在一些实施例中，系统还可以包括脑监测元件，并且处理器可以被配置为监视脑信号并且基于脑信号来改变治疗输出。

33. 发明授权

US07991467B2 Remotely enabled pacemaker and implantable subcutaneous cardioverter/defibrillator system 有权
标题翻译：远程启动心脏起搏器和植入式皮下心律转复/除颤器系统
公开(公告)号：US07991467B2
公开(公告)日：2011-08-02
申请号：US11114474
申请日：2005-04-26
申请人： H. Toby Markowitz , Douglas A. Hettrick , William J. Combs , Todd J. Sheldon , David L. Thompson , Raja N. Ghanem , Kevin A. Wanasek
发明人： H. Toby Markowitz , Douglas A. Hettrick , William J. Combs , Todd J. Sheldon , David L. Thompson , Raja N. Ghanem , Kevin A. Wanasek
IPC分类号： A61B5/02 , A61N1/362
CPC分类号： A61N1/3962 , A61N1/025 , A61N1/37211 , A61N1/37229 , A61N1/37288
摘要： Subcutaneous Implantable cardioverter-defibrillators (SubQ ICDs) are disclosed that are entirely implantable subcutaneously with minimal surgical intrusion into the body of the patient and provide distributed cardioversion-defibrillation sense and stimulation electrodes for delivery of cardioversion-defibrillation shock and pacing therapies across the heart when necessary. The SubQ ICD is implemented with other implantable and external medical devices and communicates to provide drugs and therapy in a coordinated and synergistic manner.
摘要翻译：皮下植入式心脏复律除颤器（SubQ ICD）被公开，其完全可植入皮下，以最小的外科手术入侵患者体内，并提供分布式心脏复律除颤感和刺激电极，用于在整个心脏中递送心脏复律除颤休克和起搏疗法必要。 SubQ ICD与其他植入式和外部医疗设备一起实施，并以协调和协同的方式进行通信以提供药物和治疗。

34. 发明申请

US20090048584A1 Closed Loop Medicament Pump 审中-公开
标题翻译：闭环药泵
公开(公告)号：US20090048584A1
公开(公告)日：2009-02-19
申请号：US12238925
申请日：2008-09-26
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61K9/22
CPC分类号： A61B5/4839 , A61B5/0002 , A61B5/0028 , A61B5/14532
摘要： A device to determine the level of a substance of interest in a patient's body and provide a therapeutic amount of medicament is disclosed. The level of a substance of interest in the patient's body is determined by iontopheretically sampling the patient's blood and then analyzing the resulting sample to determine the level of the substance of interest. The information about the level of a substance of interest is transmitted to an implanted drug pump in the patient's body. In the preferred embodiment, the substance of interest sensor is an external sensor applied to the user's skin. In an alternate embodiment, the sensor may be implanted. The preferred method of transmitting information about the level of a substance of interest determined by the sensor is transmitted to an implanted drug pump in the patient's body is via a so called “body bus”. The “body bus” is a telemetry system where the patient's own body provides the interconnection between the iontopheretic device and the implanted drug pump.
摘要翻译：公开了一种用于确定患者体内感兴趣物质的水平并提供治疗量的药物的装置。患者体内感兴趣的物质的水平通过对患者的血液进行离子电离取样来确定，然后分析所得样品以确定感兴趣物质的水平。关于感兴趣物质的水平的信息被传送到患者体内的植入药物泵。在优选实施例中，感兴趣的物质传感器是应用于使用者皮肤的外部传感器。在替代实施例中，可以植入传感器。传送关于感兴趣物质确定的物质的水平的信息的优选方法通过所谓的“身体总线”传送到患者体内的植入药物泵。 “身体总线”是一种遥测系统，其中病人自己的身体提供了离子电影装置和植入的药物泵之间的互连。

35. 发明授权

US07313529B2 Portable extender for data transmission within a medical device communication system 有权
标题翻译：用于在医疗设备通信系统内进行数据传输的便携式扩展器
公开(公告)号：US07313529B2
公开(公告)日：2007-12-25
申请号：US09887762
申请日：2001-06-22
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： G06F19/00
CPC分类号： A61N1/37235 , A61N1/37247 , A61N1/37252 , G06F19/00 , G06F19/3418 , G06Q50/22 , G06Q50/24 , Y10S128/903
摘要： Apparatus and method for managing chronic home care of patients with one or more implanted medical devices (IMDs) includes a mobile portable device for use by a visiting nurse. Specifically, the portable device integrates various systems to enable the nurse to schedule her day and get directions to a first and subsequent visit destination via a GPS system or equivalent. The portable device includes an identification system including a security protocol to identify the nurse/home health care provider. Additionally, the portable device incorporates a communication system such as a cellular phone that would enable the nurse to connect to other clinical support personnel such as a doctor or a specialist. The portable device further includes a wireless communication system that enables communication between the portable device and one or more IMDs in a patient. Upon arrival at the patient's home, the nurse may download data from the one or more IMDs directly into the portable device. This data could in turn be downloaded immediately or later to a remote viewing center via conventional data transmission systems. Other medical data such as blood pressure measurements and vital physiologic signals may be entered into the portable device using a digitizer pen, voice input or equivalent. Similar to the IMD data, this medical data could be transmitted to the remote location from the portable device.
摘要翻译：用于管理患有一个或多个植入式医疗装置（IMD）的患者的慢性家庭护理的装置和方法包括由访问护士使用的移动便携式装置。具体地，便携式设备集成了各种系统，以使护士可以安排她的一天，并通过GPS系统或等同物获取到第一个和后续的访问目的地的指示。便携式设备包括识别系统，其包括用于识别护士/家庭医疗保健提供者的安全协议。此外，便携式设备包括诸如蜂窝电话的通信系统，其将使护士能够连接到诸如医生或专家的其他临床支持人员。便携式设备还包括能够使便携式设备与患者中的一个或多个IMD之间进行通信的无线通信系统。到达患者家时，护士可以将数据从一个或多个IMD直接下载到便携式设备中。该数据可以通过常规数据传输系统立即或稍后地被下载到远程观看中心。可以使用数字化笔，语音输入或等同物将诸如血压测量和生理生理信号的其他医学数据输入到便携式设备中。类似于IMD数据，该医疗数据可以从便携式设备传输到远程位置。

36. 发明授权

US07195599B2 Instrumented catheter with distance compensation to sense vulnerable plaque 有权
标题翻译：仪器导管用距离补偿来感测易损斑块
公开(公告)号：US07195599B2
公开(公告)日：2007-03-27
申请号：US10692145
申请日：2003-10-22
申请人： James Kevin Carney , David L. Thompson , Mark Brister
发明人： James Kevin Carney , David L. Thompson , Mark Brister
IPC分类号： A61B5/00
CPC分类号： A61B5/01 , A61B5/02007 , A61B5/1076
摘要： A method and apparatus for determining vulnerable plaque in a cardiovascular lumen is disclosed. In one embodiment, a guide member comprising a temperature sensor and a distance sensor are inserted into the cardiovascular lumen. The temperature of the cardiovascular wall is measured with the temperature sensor, and the distance from the temperature sensor to the cardiovascular wall is determined. The cardiovascular wall temperature is adjusted based on the distance determination, and the vulnerable plaque is determined based on the adjusted wall temperature measurement.
摘要翻译：公开了一种用于确定心血管内腔中脆弱斑块的方法和装置。在一个实施例中，将包括温度传感器和距离传感器的引导构件插入心血管内腔。用温度传感器测量心血管壁的温度，并确定从温度传感器到心血管壁的距离。基于距离测定调节心血管壁温度，并根据调整后的壁温测定值确定易损斑块。

37. 发明授权

US07177699B2 Lifestyle management system 有权
标题翻译：生活管理系统
公开(公告)号：US07177699B2
公开(公告)日：2007-02-13
申请号：US10824740
申请日：2004-04-15
申请人： Willa Fabian , David Moore , Hal Kaufman , David L. Thompson
发明人： Willa Fabian , David Moore , Hal Kaufman , David L. Thompson
IPC分类号： A61N1/36
CPC分类号： A61B5/0031 , A61N1/08 , A61N1/37 , Y10S128/903
摘要： A patient monitoring system in cooperation with IMDs provides information, direction and counseling to patients. Specifically, a combination of lifestyle parameters, such as, for example, diet, exercise, weight, medication and environmental factors such as, for example, temperature, UV factor, pollen count, humidity, air pollution index, are integrated to provide a seamless, comprehensive, chronic monitoring system and support for patients. The system includes a home monitor, IMD, and a remote expert station in operable data communications therebetween. Personal data such as weight, environmental data, food data from refrigerators and pantry, type of exercise equipment, medication, physiologically significant events, physician treatment plan and the like are integrated with IMD data to provide continuous patient care, counseling, consultation and notification. The remote expert station enables doctors and other health care providers to review, monitor current and long-term trends of the patient's health status and dispense clinical care as needed.
摘要翻译：与IMD合作的患者监测系统为患者提供信息，指导和咨询。具体地说，整合了诸如例如饮食，运动，体重，药物和环境因素（例如温度，UV因子，花粉计数，湿度，空气污染指数）的生活方式参数的组合以提供无缝全面，长期的监测系统和对患者的支持。该系统包括家庭监视器，IMD和远程专家站之间可操作的数据通信。将体重，环境数据，冰箱和食品室的食物数据，运动器材类型，药物，生理重要事件，医师治疗计划等个人数据与IMD数据相结合，提供持续的病人护理，咨询，咨询和通知。远程专家站使医生和其他保健提供者能够检查，监测患者健康状况的当前和长期趋势，并根据需要分配临床护理。

38. 发明授权

US07027872B2 Variable encryption scheme for data transfer between medical devices and related data management systems 有权
公开(公告)号：US07027872B2
公开(公告)日：2006-04-11
申请号：US10620497
申请日：2003-07-16
申请人： David L. Thompson
发明人： David L. Thompson
IPC分类号： A61N1/08
CPC分类号： A61N1/37282 , A61N1/37252 , G06F19/00 , G06F19/3418 , G06Q50/22 , Y10S128/903
摘要： The present invention provides for an encryption apparatus, system, and method in which data from an Implantable Medical Device (IMD) and a data center could be transferred based on a differentiated encryption system. The encryption scheme allows for the differentiation, segregation, and classification of data at required or needed levels of security. Before transfer of the data, either from an IMD or any other part of a support network for the IMDs, the encryption device begins to distinguish the data. The variable data is then classified based on various levels of security having distinct encryption protocols. After classification the data is encrypted based on the data's level of security. The data is then transmitted. Upon being received the data is then segregated based on whether the data is encrypted. The encrypted data is then de-encrypted and interpreted.

39. 发明授权

US06909920B2 System and method for positioning an implantable medical device within a body 有权
标题翻译：将可植入医疗装置定位在体内的系统和方法
公开(公告)号：US06909920B2
公开(公告)日：2005-06-21
申请号：US09844628
申请日：2001-04-27
申请人： Nicolaas M. Lokhoff , David L. Thompson
发明人： Nicolaas M. Lokhoff , David L. Thompson
IPC分类号： A61N1/05
CPC分类号： A61N1/057 , A61N2001/0585
摘要： A transvenous implantable medical device adapted for implantation in a body, and which is particularly adapted for use in a vessel such as the coronary sinus or cardiac great vein. The implantable medical device may take the form of a lead or catheter, and includes an extendable distal fixation member such as a helix. In one embodiment, the fixation member is a helix constructed of a shape memory metal or other super-elastic material. Upon deployment, the helix assumes a predetermined helix shape larger than the diameter of the lead body diameter. The helix functions to wedge or fix the lead within the vessel in a manner that does not impede the flow of blood through the vessel. The helix may be retracted for ease of repositioning and/or removal. In one embodiment of the invention, the fixation member may be advanced using a stiffening member such as a stylet. In another embodiment, the helix is coupled to a coiled conductor such that rotation of the conductor extends or retracts the helix. According to yet another aspect of the invention, a helix lumen including a flexible fluid-tight seal may be utilized to house the helix when it is in the retracted position.
摘要翻译：一种经静脉植入式医疗装置，适于植入体内，特别适用于血管如冠状窦或心脏大静脉。可植入医疗装置可以采用导联或导管的形式，并且包括可延伸的远端固定构件，例如螺旋。在一个实施例中，固定构件是由形状记忆金属或其它超弹性材料构成的螺旋。在部署时，螺旋呈现比引线体直径的直径大的预定螺旋形状。螺旋线用于以不妨碍血液通过血管的方式楔入或固定血管内的引线。螺旋可以缩回以便于重新定位和/或移除。在本发明的一个实施例中，固定构件可以使用诸如探针的加强构件前进。在另一个实施例中，螺旋连接到螺旋导体，使得导体的旋转延伸或缩回螺旋。根据本发明的另一方面，当螺旋管处于缩回位置时，可以使用包括柔性流体密封的螺旋管来容纳螺旋。

40. 发明授权

US06749581B2 Variable infusion rate catheter 失效
标题翻译：可变输液导管
公开(公告)号：US06749581B2
公开(公告)日：2004-06-15
申请号：US09776436
申请日：2001-02-02
申请人： David L. Thompson , Michael F. Mattes , Lary R. Larson , Kenneth T. Heruth
发明人： David L. Thompson , Michael F. Mattes , Lary R. Larson , Kenneth T. Heruth
IPC分类号： A61B1739
CPC分类号： A61M5/16881 , A61M5/16813 , A61M2205/3507 , A61M2205/50
摘要： A medical device known as a catheter is configured with a variable infusion rate to deliver a therapeutic substance such as pharmaceutical compositions, genetic materials, and biologics to treat a variety of medical conditions such as pain, spastisity, cancer, and other diseases in humans and other animals. The variable infusion rate catheter provides clinician with increased flexibility, versatility, and many other improvements. The variable infusion rate catheter has a Micro Electro Mechanical System (MEMS) flow restriction with a variable infusion rate. The MEMS flow restriction is fluidly coupled to the catheter to receive therapeutic substance dispensed from a therapeutic substance delivery device and restrict the therapeutic substance flow to a desired infusion rate. Many embodiments of the variable infusion rate catheter and its methods of operation are possible.
摘要翻译：被称为导管的医疗装置被配置为具有可变的输注速率以递送治疗物质，例如药物组合物，遗传物质和生物制剂，以治疗各种医学病症如疼痛，口臭，癌症和其它人类疾病，以及其他动物。可变输注导管为临床医生提供了更大的灵活性，多功能性和许多其他改进。可变输注速率导管具有可变输液速率的微机电系统（MEMS）流量限制。 MEMS流量限制流体耦合到导管以接收从治疗物质递送装置分配的治疗物质，并将治疗物质流量限制到所需的输注速率。可变输注速率导管的许多实施例及其操作方法是可能的。

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