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31. 发明申请

US20100204719A1 RESTRICTIVE AND/OR OBSTRUCTIVE IMPLANT FOR INDUCING WEIGHT LOSS 有权
标题翻译：用于诱导重量损失的限制性和/或阻碍性植入物
公开(公告)号：US20100204719A1
公开(公告)日：2010-08-12
申请号：US12765177
申请日：2010-04-22
申请人： Daniel J. Balbierz , William L. Athas , John Lunsford , William S. Eubanks, JR. , Kevin van Bladel
发明人： Daniel J. Balbierz , William L. Athas , John Lunsford , William S. Eubanks, JR. , Kevin van Bladel
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064
CPC分类号： A61F5/0086 , A61B17/12009 , A61B2017/12018 , A61F5/003 , A61F5/0036
摘要： Described herein is a system for inducing weight loss in a patient, which comprises an extragastric space occupier positionable in contact with an exterior surface of a stomach wall to form an inward protrusion of wall into the stomach, and a retention device positionable in contact with the wall to retain the inward protrusion and to thereby capture the extragastric space occupier within the protrusion.
摘要翻译：本文描述了一种用于在患者体内引起体重减轻的系统，该系统包括可与胃壁的外表面接触定位的胃内空间占据器，以形成壁向胃内的向内突出部，以及可定位成与胃壁接触的保持装置壁以保持向内的突出部，从而捕获突出部内的胃内空间占据。

32. 发明授权

US07717843B2 Restrictive and/or obstructive implant for inducing weight loss 有权
标题翻译：用于诱导体重减轻的限制性和/或阻塞性植入物
公开(公告)号：US07717843B2
公开(公告)日：2010-05-18
申请号：US11114400
申请日：2005-04-26
申请人： Daniel J. Balbierz , William L. Athas , John Lunsford , William S. Eubanks, Jr. , Kevin van Bladel
发明人： Daniel J. Balbierz , William L. Athas , John Lunsford , William S. Eubanks, Jr. , Kevin van Bladel
IPC分类号： A61F2/00
CPC分类号： A61F5/0086 , A61B17/12009 , A61B2017/12018 , A61F5/003 , A61F5/0036
摘要： Described herein is a system for inducing weight loss in a patient, which comprises an extragastric space occupier positionable in contact with an exterior surface of a stomach wall to form an inward protrusion of wall into the stomach, and a retention device positionable in contact with the wall to retain the inward protrusion and to thereby capture the extragastric space occupier within the protrusion.
摘要翻译：本文描述了一种用于引起患者体重减轻的系统，其包括可与胃壁的外表面接触的胃内空间占据器，以形成壁向胃内的向内突出部，以及可定位成与胃壁接触的保持装置壁以保持向内的突出部，从而捕获突出部内的胃内空间占据。

33. 发明申请

US20100116867A1 MULTI-FIRE STAPLING SYSTEMS AND METHODS FOR DELIVERING ARRAYS OF STAPLES 有权
标题翻译：多层消防系统和传送堆叠阵列的方法
公开(公告)号：US20100116867A1
公开(公告)日：2010-05-13
申请号：US12268404
申请日：2008-11-10
申请人： Daniel J. Balbierz , Pablo R. Hambly , Jason S. Stewart , David Cole
发明人： Daniel J. Balbierz , Pablo R. Hambly , Jason S. Stewart , David Cole
IPC分类号： A61B17/10
CPC分类号： A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/115 , A61B2017/07214 , A61B2017/07228 , A61B2017/07271 , A61F5/0086
摘要： A staple housing includes an array of staples each in a staple delivery position or “ready position” ready to be fired into target tissue. A staple driver is advanceable to drive the ready-position staples from the staple head into the tissue using staple pushers. During use, the staples in the ready positions are simultaneously fired into the target tissue using the staple pushers, forming an array of staples in the target tissue. After the array has been fired, one or more feed mechanisms within the staple housing advance a second group of staples from one or more staple storage locations into the ready positions in preparation for firing of the second group of staples.
摘要翻译：订书钉壳体包括各自位于钉送出位置的订书钉阵列或准备好被烧制到目标组织中的“就绪位置”。订书钉驱动器可前进，以使用订书钉推动器将订书钉从订书钉驱动到组织中。在使用期间，准备位置中的订书钉使用订书钉推动器同时被烧制到目标组织中，从而在目标组织中形成一排钉。在阵列被点火之后，钉仓壳体内的一个或多个进给机构将第二组订书钉从一个或多个订书钉存储位置推进到就绪位置，以准备第二组钉的点火。

34. 发明申请

US20090171383A1 GASTRIC SPACE OCCUPIER SYSTEMS AND METHODS OF USE 审中-公开
标题翻译：胃肠外营养系统及其使用方法
公开(公告)号：US20090171383A1
公开(公告)日：2009-07-02
申请号：US12270607
申请日：2008-11-13
申请人： David Cole , Samuel T. Crews , Bretton Swope , Andrew Smith , John Lunsford , Daniel J. Balbierz
发明人： David Cole , Samuel T. Crews , Bretton Swope , Andrew Smith , John Lunsford , Daniel J. Balbierz
IPC分类号： A61M29/02
CPC分类号： A61F5/0036 , A61F5/003
摘要： Systems for controlling obesity utilize a number of space occupiers positioned in the stomach to reduce the effective volume of the stomach. Such arrangements provides sufficient stomach volume consumption to induce weight loss, but enable use of space occupiers that are proportioned to minimize the threat of obstruction even if they should migrate into the intestine. In general, numerous small volume space occupiers are placed in the stomach such that the total volume equals or exceeds the single volume of prior art single unit space occupiers. However, each individual space occupier is proportioned so that it will pass without obstruction if it moves into the intestine.
摘要翻译：用于控制肥胖的系统利用位于胃中的多个空间占用者来减少胃的有效体积。这种布置提供足够的胃体积消耗以引起体重减轻，但是能够使用成比例的空间占用者，以尽量减少阻塞的威胁，即使它们应该迁移到肠中。通常，许多小容量空间占用者被放置在胃中，使得总体积等于或超过现有技术的单个单位空间占用者的单个体积。然而，每个单独的空间占有者是成比例的，以便如果它进入肠道，它将不会阻塞。

35. 发明申请

US20080294179A1 DEVICES AND METHODS FOR STOMACH PARTITIONING 审中-公开
标题翻译：设备和方法进行分离
公开(公告)号：US20080294179A1
公开(公告)日：2008-11-27
申请号：US12119329
申请日：2008-05-12
申请人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Bretton Swope , Justen England
发明人： Daniel J. Balbierz , Dave Cole , Samuel T. Crews , Bretton Swope , Justen England
IPC分类号： A61B17/08
CPC分类号： A61F5/0086 , A61B17/0643 , A61B17/068 , A61B17/072 , A61B17/07207 , A61B17/10 , A61B17/1155 , A61B17/29 , A61B2017/00349 , A61B2017/0647 , A61B2017/07228 , A61B2017/2905 , A61B2017/306 , A61F5/0083 , A61F5/0089
摘要： A device and method for remodeling or partitioning a body cavity, hollow organ or tissue tract includes graspers operable to engage two or more sections of tissue within a body cavity and to draw the engaged tissue between a first and second members of a tissue remodeling tool. The two or more pinches of tissue are held in complete or partial alignment with one another as staples or other fasteners are driven through the pinches, thus forming a four-layer tissue plication. Over time, adhesions formed between the opposed serosal layers create strong bonds that can facilitate retention of the plication over extended durations, despite the forces imparted on them by stomach movement. A cut or cut-out may be formed in the plication during or separate from the stapling step to promote edge-to-edge healing effects that will enhance tissue knitting/adhesion.
摘要翻译：用于重建或分隔体腔，中空器官或组织道的装置和方法包括可操作以接合体腔内的组织的两个或更多个部分并且将所接合的组织在组织重塑工具的第一和第二构件之间拉动的抓握器。当钉或其它紧固件通过夹持物驱动时，两个或更多个组织的夹持件彼此完全或部分地对准，从而形成四层组织折叠。随着时间的推移，在相对的浆膜层之间形成的粘连产生强力的粘合，尽管通过胃运动赋予它们的力，也可以有助于在延长的持续时间内保持脓肿。可以在缝合步骤期间或与缝合步骤分开形成切口或切口，以促进边缘到边缘愈合效果，从而增强组织编织/粘合。

36. 发明授权

US07419487B2 Apparatus for detecting and treating tumors using localized impedance measurement 有权
标题翻译：使用局部阻抗测量检测和治疗肿瘤的装置
公开(公告)号：US07419487B2
公开(公告)日：2008-09-02
申请号：US09916214
申请日：2001-07-25
申请人： Theodore C. Johnson , Daniel J. Balbierz , Robert M. Pearson
发明人： Theodore C. Johnson , Daniel J. Balbierz , Robert M. Pearson
IPC分类号： A61B18/18
CPC分类号： A61B18/18 , A61B18/1477 , A61B2018/00011 , A61B2018/00083 , A61B2018/00196 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/00875 , A61B2018/124 , A61B2018/1273 , A61B2018/128 , A61B2018/1497 , A61B2218/002
摘要： An apparatus for treating tumors comprises an elongated delivery device that includes a lumen and is maneuverable in tissue. An impedance sensor array is deployable from the elongated device and configured to be coupled to at least one of an energy source or a switching device. The impedance array includes a plurality of resilient members, at least one of the plurality being positionable in the elongated device in a compacted state and deployable with curvature into tissue from the elongated device in a deployed state. In the deployed state, the plurality of resilient members defines a sample volume. At least one of the resilient members includes an impedance sensor and at least a portion of the array is configured to sample tissue impedance through a plurality of conductive pathways. An energy delivery device is coupled to one of the array, the at least one resilient member or the elongated device.
摘要翻译：用于治疗肿瘤的装置包括细长递送装置，其包括内腔并且可在组织中操纵。阻抗传感器阵列可从细长装置展开并且被配置为耦合到能量源或开关装置中的至少一个。所述阻抗阵列包括多个弹性构件，所述多个弹性构件中的至少一个可处于处于压实状态的所述细长装置中，并且在展开状态下可从所述细长装置以曲率展开到组织中。在展开状态下，多个弹性构件限定样本体积。弹性构件中的至少一个包括阻抗传感器，并且阵列的至少一部分被配置成通过多个导电路径采样组织阻抗。能量输送装置联接到阵列中的一个，至少一个弹性构件或细长装置。

37. 发明申请

US20080065122A1 Restrictive and/or obstructive implant system for inducing weight loss 有权
标题翻译：用于诱导体重减轻的限制性和/或阻塞性植入物系统
公开(公告)号：US20080065122A1
公开(公告)日：2008-03-13
申请号：US11439461
申请日：2006-05-23
申请人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
发明人： Richard S. Stack , Daniel J. Balbierz , William L. Athas , John Lunsford , Kevin van Bladel , Ashik Mohan , Samuel T. Crews , Shuji Uemura , Robert H. Hawes
IPC分类号： A61B17/08
CPC分类号： A61F5/0086 , A61B17/00234 , A61B2017/00292 , A61B2017/00827 , A61B2017/00991 , A61F5/0089 , A61M25/0194
摘要： The present application describes an implant system useable for positioning an implant device such as a device useful for restricting passage of ingested food into the stomach. In one embodiment, the disclosed system includes a plurality of anchors that may be coupled to tissue within the stomach, or to a tissue tunnel formed by plicating stomach wall tissue. The anchor includes a loop. During use, the implant device is inserted through the loop and expanded such that it retains its position within the loop until removed. Instruments for implanting and explanting the implant device are also described.
摘要翻译：本申请描述了可用于定位植入装置的植入物系统，例如用于限制摄取的食物进入胃的通道的装置。在一个实施例中，所公开的系统包括可以连接到胃内的组织或通过使胃壁组织变细而形成的组织隧道的多个锚固件。锚包括一个环。在使用期间，植入装置插入通过环并且膨胀使得其保持其在环内的位置，直到移除。还描述了用于植入和外植植入装置的器械。

38. 发明授权

US07160296B2 Tissue ablation apparatus and method 有权
标题翻译：组织消融装置及方法
公开(公告)号：US07160296B2
公开(公告)日：2007-01-09
申请号：US10142713
申请日：2002-05-10
申请人： Rob Pearson , Steve A. Daniel , Daniel J. Balbierz , Kee S. Lee , Jessica Liang , Martha Getaneh
发明人： Rob Pearson , Steve A. Daniel , Daniel J. Balbierz , Kee S. Lee , Jessica Liang , Martha Getaneh
IPC分类号： A61B18/18
CPC分类号： A61B18/1477 , A61B2018/0016 , A61B2018/00577 , A61B2018/00654 , A61B2018/00702 , A61B2018/00714 , A61B2018/00791 , A61B2018/00797 , A61B2018/00875 , A61B2018/143 , A61B2018/1472 , A61B2018/1475
摘要： A tissue-ablation method and apparatus are disclosed. The apparatus includes a plurality of RF ablation electrodes, and a plurality of sensor elements, each movable from retracted to deployed positions in a tissue to be ablated. A control device in the apparatus is operatively connected to the electrodes for supplying an RF power to the electrodes, to produce tissue ablation that advances from individual-electrode ablation regions to fill a combined-electrode ablation volume. The control device is operatively connected to the sensor elements for determining the extent of ablation in the regions of the sensor elements. The supply of RF power to the electrodes can thus be regulated to control the level and extent of tissue ablation throughout the combined-electrode volume. The electrodes are preferably hollow-needle electrodes through which liquid can be infused into the tissue, also under the control of the control unit, to modulate and optimize tissue ablation.
摘要翻译：公开了组织消融方法和装置。该装置包括多个RF消融电极和多个传感器元件，每个传感器元件可从收缩的组织中的缩回到展开位置移动以进行烧蚀。设备中的控制装置可操作地连接到电极，以向电极提供RF功率，以产生从单个电极消融区域前进以填充组合电极消融体积的组织消融。控制装置可操作地连接到传感器元件，以确定传感器元件区域中的消融程度。因此，可以调节对电极的RF功率的供应以控制整个组合电极体积中的组织消融的水平和程度。电极优选是中空针电极，液体也可以在控制单元的控制下输注到组织中，以调节和优化组织消融。

39. 发明授权

US06962587B2 Method for detecting and treating tumors using localized impedance measurement 有权
标题翻译：使用局部阻抗测量法检测和治疗肿瘤的方法
公开(公告)号：US06962587B2
公开(公告)日：2005-11-08
申请号：US09916235
申请日：2001-07-25
申请人： Theodore C. Johnson , Daniel J. Balbierz , Robert Pearson
发明人： Theodore C. Johnson , Daniel J. Balbierz , Robert Pearson
IPC分类号： A61B5/05 , A61B18/12 , A61B18/14 , A61B18/18
CPC分类号： A61B18/18 , A61B18/1477 , A61B2018/00011 , A61B2018/00083 , A61B2018/00196 , A61B2018/00577 , A61B2018/00642 , A61B2018/00654 , A61B2018/00875 , A61B2018/124 , A61B2018/1273 , A61B2018/128 , A61B2018/1497 , A61B2218/002
摘要： An embodiment of the invention provides a method for detecting and treating a tumor using tissue localized volumetric impedance measurement. The method includes providing an impedance measurement apparatus having a plurality of resilient members deployable with curvature and configured to sample tissue impedance through a plurality of conductive pathways. The apparatus is configured to be coupled to at least one of an energy delivery device, a power supply, a switching device or logic resources. The apparatus is then positioned at a selected tissue site and the impedance array deployed to define a sample volume. The impedance array is then utilized to make impedance measurements through a plurality of conductive pathways. Information from the impedance measurements is then utilized to determine a tissue condition of the sample volume. Energy is then delivered from the energy delivery device to ablate or necrose at least a portion of the tumor.
摘要翻译：本发明的一个实施方案提供了一种使用组织局部体积阻抗测量来检测和治疗肿瘤的方法。该方法包括提供阻抗测量装置，其具有可弯曲展开的多个弹性构件，并且被配置为通过多个导电路径采样组织阻抗。该装置被配置为耦合到能量输送装置，电源，开关装置或逻辑资源中的至少一个。然后将装置定位在选定的组织部位，并且部署阻抗阵列以限定样品体积。然后阻抗阵列用于通过多个导电路径进行阻抗测量。然后利用来自阻抗测量的信息来确定样品体积的组织条件。然后将能量从能量递送装置递送至至少一部分肿瘤的烧蚀或死皮。

40. 发明授权

US5902282A Step-down catheter 失效
标题翻译：降压导管
公开(公告)号：US5902282A
公开(公告)日：1999-05-11
申请号：US774975
申请日：1996-12-26
申请人： Daniel J. Balbierz
发明人： Daniel J. Balbierz
IPC分类号： A61M25/00 , A61M25/06 , A61M25/08 , A61M5/00
CPC分类号： A61M25/0023 , A61M25/0668 , A61M25/0021
摘要： The invention relates to a catheter and a method of placing a catheter that includes a substantially tubular body portion having an outside diameter no less than the inside diameter of an opening in a catheter introducer adapted to insert a portion of the catheter into a patient's body. The catheter also includes a transition member portion adjacent to a first end of the tubular body portion. The transition member portion has an outside diameter that is less than the outside diameter of the tubular body portion and less than the inside diameter of the opening in the catheter introducer. The invention contemplates that the transition member can be coupled to the end of the tubular body portion, integrally formed with the body portion, or extends from the end of body portion and be removable from a distal end of the body portion. A benefit of the catheter including a transition member portion having an outside diameter that is less than the inside diameter of the opening in the catheter introducer is that it allows a means for inserting a through the introducer catheter which is larger than the inside diameter of the introducer. This provides the benefit of over-the-needle insertion with regard to needle size, but allows for a larger catheter to be placed in the vein by the subsequent removal of the introducer once the transition member portion is placed in the vein.
摘要翻译：本发明涉及一种导管和放置导管的方法，该导管包括基本上管状的本体部分，其具有不小于适于将导管的一部分插入患者体内的导管导引器中的开口的内径。导管还包括与管状主体部分的第一端相邻的过渡构件部分。过渡构件部分具有小于管状体部分的外径的外径，并且小于导管导引器中的开口的内径。本发明设想，过渡构件可以联接到与主体部分整体形成的管状主体部分的端部，或者从主体部分的端部延伸并且可以从主体部分的远端移除。包括具有小于导管导引器中的开口的内径的外径的过渡构件部分的导管的益处在于其允许用于插入通过导引器导管的装置，该装置大于所述导管导管的内径介绍人这提供了关于针尺寸的针插入的益处，但是一旦过渡构件部分被放置在静脉中，则允许通过随后移除导引器将更大的导管放置在静脉中。

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