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    • 32. 发明申请
    • IMPLANTABLE ENCAPSULATION DEVICES
    • 可植入封装器件
    • WO2018089397A2
    • 2018-05-17
    • PCT/US2017/060494
    • 2017-11-08
    • W.L. GORE & ASSOCIATES, INC.
    • CULLY, Edward, H.GUNZEL, EdwardKNISLEY, KeithRUSCH, GregZAMBOTTI, Lauren
    • A61F2/02
    • The present disclosure relates to implantable encapsulation devices for housing a biological moiety or a therapeutic device that contains a biological moiety. Particularly, aspects of the present disclosure are directed to an implantable apparatus that includes a distal end, a proximal end, a manifold including at least one access port positioned either at the distal end or the proximal end, and a plurality of containment tubes affixed to the manifold and in fluid communication with the at least one access port. Additionally, the encapsulation device may contain a flush port and a tube that are fluidly connected to the manifold. The containment tubes may contain therein a biological moiety (e.g., cells) or a therapeutic device (e.g. a cell encapsulation member).
    • 本公开涉及用于容纳生物部分的可植入包封装置或包含生物部分的治疗装置。 具体地,本公开的方面涉及一种可植入装置,其包括远端,近端,包括定位在远端或近端处的至少一个进入端口的歧管,以及固定到 该歧管并与该至少一个进入端口流体连通。 另外,封装装置可以包含流体连接到歧管的冲洗端口和管。 容纳管中可以包含生物部分(例如细胞)或治疗装置(例如细胞封装构件)。
    • 35. 发明申请
    • SHOE LASTS FOR USE WITH CONFORMABLE BOOTIES, SHOE INSERTS, FOOTWEAR ASSEMBLIES AND WATERPROOF BREATHABLE SOCKS
    • 鞋子使用适合的鞋子,鞋子,鞋类组合和防水防水袜子
    • WO2016130200A1
    • 2016-08-18
    • PCT/US2015/062990
    • 2015-11-30
    • W.L. GORE & ASSOCIATES, INC.W.L. GORE & ASSOCIATES GMBH
    • CLOUGH, NormanNABERNIK, Stane
    • A43D3/00A43D3/02
    • A43D3/00A41B11/00A41B2400/22A43B7/125A43D3/027
    • Waterproof, breathable socks, booties, shoe inserts, and footwear assemblies containing the shoe inserts are provided. The booties and shoe inserts include a laminate of a seamless ePTFE membrane and at least one textile. The bootie is conformable over a range of sizes and shoe shapes, and may be shaped to fit numerous sizes and shapes of asymmetrical shoe lasts. The bootie may shrink to fit, or, alternatively, be stretched to fit, an asymmetrical last having a desired size to form a shoe insert. Such a conformable bootie eliminates the need to have multiple sizes of shoe inserts correlating to particular shoe sizes, in embodiments where the ePTFE is seamless and continuous, the shoe insert eliminates the need for a waterproof seam tape, which is conventionally used to make shoe inserts waterproof. Methods of forming the socks, booties, and shoe inserts are also provided. Unique lasts and sock constructions are also provided.
    • 提供了防水,透气的袜子,靴子,鞋子插入件和包含鞋插入件的鞋类组件。 靴子和鞋子插入物包括无缝ePTFE膜和至少一种织物的层压体。 这种靴子在一系列尺寸和鞋子形状上是一致的,并且可以被成形为适合不对称鞋子的许多尺寸和形状。 靴子可以收缩以适应,或者可选地被拉伸以适合具有期望尺寸以形成鞋插入件的不对称的最后。 这种适合的靴子消除了在具有无缝且连续的优点的实施例中,具有与特定鞋子尺寸相关的多种尺寸的鞋子插件的需要,鞋子插入件消除了对通常用于制造鞋子插入物的防水缝带的需要 防水。 还提供了形成袜子,靴子和鞋子插入物的方法。 还提供独特的持续和袜子结构。
    • 36. 发明申请
    • BIFURCATED GRAFT DEVICE
    • 双刃磨刀装置
    • WO2015153268A1
    • 2015-10-08
    • PCT/US2015/022684
    • 2015-03-26
    • W.L. GORE & ASSOCIATES, INC.
    • DUNN, Annette
    • A61F2/07A61F2/06
    • A61F2/856A61F2/07A61F2002/065A61F2002/072A61F2230/0065A61F2230/0067A61F2230/0095A61F2240/001A61F2240/002Y10T156/10
    • A bifurcated graft including a first branch having a first leg graft; a second branch having a second leg graft spaced apart from and not overlapping the first leg graft; and a trunk including a first layer having a first portion, a second portion, and a saddle extending therebetween the first portion and the second portion. Each of the first portion and second portion have opposite side edges that are spaced apart to define a first width. The saddle has opposite sides that are spaced apart to define a second width. The second width of the saddle is less than the first width of each of the first portion and second portion. The saddle extends along a bifurcation between the first leg graft and second leg graft.
    • 包括具有第一腿部移植物的第一分支的分叉移植物; 具有与所述第一腿移植物间隔开并且不与所述第一腿移植物重叠的第二腿部移植物的第二分支; 以及主体,其包括具有第一部分的第一层,第二部分和在其之间延伸的第一部分和第二部分的鞍座。 第一部分和第二部分中的每一个具有间隔开以限定第一宽度的相对侧边缘。 鞍座具有相对的两侧,其间隔开以限定第二宽度。 鞍座的第二宽度小于第一部分和第二部分中的每一个的第一宽度。 鞍座沿着第一腿部移植物和第二腿部移植物之间的分叉延伸。
    • 38. 发明申请
    • HUMIDIFICATION CONTROL DEVICE
    • 湿度控制装置
    • WO2015053915A1
    • 2015-04-16
    • PCT/US2014/056241
    • 2014-09-18
    • W.L. GORE & ASSOCIATES, INC.
    • SHEALY, GlennLEVY, Brian
    • H01M8/04C25B9/10C25B1/04
    • C25D17/002C25B1/10C25B9/10C25B13/08F21S45/33H01M8/04835Y02E60/366
    • A humidification control device and an apparatus implementing the humidification control device is provided. The device includes a membrane electrode assembly (MEA) for the control of humidity in an enclosed space via electrolysis. The MEA includes an anode, a cathode and a proton exchange membrane (PEM) disposed between the anode and the cathode. The PEM is selected to increase the efficiency of the humidification control device by decreasing the back diffusion of water across the PEM. The PEM may include a functional tetrafluoroethylene (TFE) copolymer having a polymer chain of TFE and at least one comonomer having a proton conducting functional group pendant to said polymer chain. The comonomer may be present in an amount from about 0.01 mol. % to about 7 mol. % of the TFE copolymer. In one embodiment, the comonomer is a fluorovinyl ether such as perfluorosulfonyl vinyl ether (PSVE).
    • 提供一种加湿控制装置和实现加湿控制装置的装置。 该装置包括用于通过电解控制封闭空间中的湿度的膜电极组件(MEA)。 MEA包括阳极,阴极和置于阳极和阴极之间的质子交换膜(PEM)。 选择PEM以通过减少水在PEM上的反向扩散来提高加湿控制装置的效率。 PEM可以包括具有TFE的聚合物链的功能性四氟乙烯(TFE)共聚物和至少一个具有垂直于所述聚合物链的质子传导官能团的共聚单体。 共聚单体可以以约0.01mol的量存在。 %至约7mol。 %的TFE共聚物。 在一个实施方案中,共聚单体是氟乙烯基醚,例如全氟磺酰基乙烯基醚(PSVE)。