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31. 发明申请

US20030216801A1 Transmyocardial implant with natural vessel graft and method 审中-公开
标题翻译：经心肌植入与天然血管移植和方法
公开(公告)号：US20030216801A1
公开(公告)日：2003-11-20
申请号：US10150621
申请日：2002-05-17
申请人： HeartStent Corporation
发明人： Katherine S. Tweden , Michael Schollmeyer
IPC分类号： A61F002/06
CPC分类号： A61F2/94 , A61F2/2493 , A61F2220/0008 , A61F2220/0075
摘要： A transmyocardial implant includes a hollow rigid conduit having a vessel portion and a myocardial portion. The vessel portion is sized to be inserted into a blood vessel segment taken from a non-coronary artery or vein. The myocardial portion is sized to extend from the vessel portion and through a myocardium into a heart chamber. The conduit has open vessel and myocardial ends on respective ends of the vessel and myocardial portions to define a blood flow pathway within an interior of the conduit between the vessel and myocardial ends. The myocardial portion is formed of a conduit material sufficiently rigid to resist deformation and closure of the pathway in response to contraction of the myocardium. The vessel portion has a radial compliance approximating a radial compliance of the vessel.
摘要翻译：经心肌植入物包括具有血管部分和心肌部分的中空刚性导管。容器部分的尺寸设置成插入从非冠状动脉或静脉取出的血管段。心肌部分的尺寸设计成从血管部分延伸并通过心肌进入心室。导管在容器和心肌部分的相应端部上具有开放的血管和心肌末端，以在容器和心肌末端之间的管道内部限定血液流动通路。心肌部分由足够刚性的导管材料形成，以抵抗心肌收缩的途径的变形和闭合。容器部分具有近似于容器的径向顺应性的径向顺应性。

32. 发明申请

US20020065478A1 Method and apparatus for revascularizing a coronary vessel with an implant having a tapered myocardial leg 失效
标题翻译：用具有锥形心肌腿的植入物血运重建冠状动脉血管的方法和装置
公开(公告)号：US20020065478A1
公开(公告)日：2002-05-30
申请号：US10043684
申请日：2002-01-09
申请人： HeartStent Corporation
发明人： Mark B. Knudson , William L. Giese
IPC分类号： A61F002/06
CPC分类号： A61B17/11 , A61B17/12022 , A61B17/12045 , A61B17/12131 , A61B17/3415 , A61B18/24 , A61B2017/00243 , A61B2017/00247 , A61B2017/1107 , A61B2017/1135 , A61B2017/12127 , A61B2018/00392 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/2493 , A61F2/856 , A61F2/90 , A61F2/954 , A61F2/958 , A61F2002/061 , A61F2002/065 , A61F2002/068 , A61F2002/821 , A61F2240/008 , Y10S623/903
摘要： A method for revascularizing a coronary vessel with a conduit through the heart wall having a diameter transition in the myocardial leg, wherein blood flow is in the direction of transition from larger to smaller diameter. A method for revascularizing a coronary vessel using an implant with a myocardial leg having a maximum cross-sectional area proximate a first end, and inserting the first end through the myocardium into a heart chamber so that the implant directs blood flow into the coronary vessel. A transmyocardial implant with a myocardial leg including point of minimum diameter and a first end with a larger diameter, and a vessel leg in fluid communication with the myocardial leg.
摘要翻译：一种通过心壁血管重建冠状血管的方法，该心脏壁在心肌腿部具有直径转变，其中血流在从较大直径向较小直径的过渡方向上。一种使用具有最接近第一端的最大横截面积的心肌腿的植入物血运重建冠状动脉血管的方法，以及将第一端穿过心肌插入心室，使得植入物将血液流入冠状血管。具有包括最小直径点和具有较大直径的第一端的心肌腿的经心肌植入物和与心肌腿流体连通的血管腿。

33. 发明授权

US6139541A Guide for transmyocardial implant 失效
标题翻译：经心肌植入指南
公开(公告)号：US6139541A
公开(公告)日：2000-10-31
申请号：US145843
申请日：1998-09-02
申请人： Guy P. Vanney , Michael L. Krogh
发明人： Guy P. Vanney , Michael L. Krogh
IPC分类号： A61B17/00 , A61B17/34 , A61F2/02
CPC分类号： A61B17/3403 , A61F2/2493 , A61B17/3468 , A61B2017/00247 , A61B2017/00252 , A61B2018/00392 , Y10S623/90
摘要： An apparatus controls a direction of formation of a hole through a myocardium for subsequent placement into the hole of a myocardial portion of a transmyocardial implant. The implant also includes a coronary portion having a coronary axis set at an implant angle to a myocardial axis of the myocardial portion. The apparatus includes a base member having base surface for placement against an epicardial surface of a heart adjacent a coronary vessel having a vessel axis. The base member has a determinable base axis for placement of the base surface on the epicardial surface with the base axis parallel with the vessel axis. A support member supports a myocardial penetrator for movement along a support axis in a line of travel parallel to the support axis and substantially restricting the myocardial penetrator from movement transverse to the support axis. The support member is secure to the base member with the support axis and base axis defining a support angle. The support angle and the implant angle are supplementary angles.
摘要翻译：一种装置控制通过心肌形成孔的方向，用于随后放置到经心肌内植入物的心肌部分的孔中。植入物还包括具有以心轴部分的心肌轴线的植入角度设置的冠状轴的冠状部分。该装置包括基部构件，其具有用于放置在与具有血管轴线的冠状血管相邻的心脏的心外膜表面上的基底表面。基部构件具有用于将基部表面放置在心外膜表面上的可确定的基本轴线，其基部轴线与血管轴线平行。支撑构件支撑心肌穿透器，用于沿平行于支撑轴线的行行沿着支撑轴线移动，并且基本上限制心肌穿透器横向于支撑轴线的移动。支撑构件固定到基部构件上，支撑轴线和基座轴线限定支撑角度。支撑角和植入角是辅助角度。

34. 发明授权

US6113823A Pyrolytic carbon transmyocardial implant 失效
标题翻译：热解碳经心肌植入
公开(公告)号：US6113823A
公开(公告)日：2000-09-05
申请号：US94136
申请日：1998-06-09
申请人： Robert A. Eno
发明人： Robert A. Eno
IPC分类号： A61F2/06 , A61L27/08 , A61L27/30 , A61L31/02 , A61L31/08 , A61L33/02 , B29C33/48 , B29C41/10 , B29C41/42
CPC分类号： A61L33/025 , A61F2/06 , A61F2/064 , A61L27/08 , A61L27/303 , A61L31/024 , A61L31/084 , Y10S264/51 , Y10S623/901
摘要： A bypass conduit having a desired hollow internal geometry for defining a bounded blood flow path from an open first end positioned in a heart chamber and an open second end connected to a lumen of a coronary vessel is made by forming a master having an external surface with an external geometry complementary to the desired internal geometry of the conduit. The external surface of the master is coated with pyrolytic carbon to define a pyrolytic carbon conduit of pyrolytic carbon bonded to the external surface of the master and with the pyrolytic carbon having an internal surface with a conduit geometry complementary to the external geometry of the master. The master is removed from the pyrolytic carbon conduit.
摘要翻译：具有期望的中空内部几何形状的旁路导管通过形成具有外表面的主体来制造，所述旁路导管具有用于从位于心室中的开放的第一端和与冠状血管的腔连接的开放的第二端限定有界的血流路径与导管的所需内部几何形状互补的外部几何形状。主体的外表面涂覆有热解碳，以限定热解碳的热解碳导管，其结合到母体的外表面，并且热解碳具有内表面，导管几何形状与主体的外部几何形状互补。主板从热解碳管道中取出。

35. 发明授权

US6076529A Transmyocardial implant with inserted vessel 失效
标题翻译：经心肌植入物插入血管
公开(公告)号：US6076529A
公开(公告)日：2000-06-20
申请号：US63161
申请日：1998-04-20
申请人： Guy P. Vanney , Katherine S. Tweden
发明人： Guy P. Vanney , Katherine S. Tweden
IPC分类号： A61B17/00 , A61F2/02 , A61F2/06 , A61B19/00
CPC分类号： A61F2/064 , A61F2/2493 , A61B2017/00252
摘要： A transmyocardial implant includes a hollow conduit inserted through a heart wall. The conduit defines a blood flow path between a heart chamber opening and a vessel opening. The heart chamber opening of the conduit is placed in communication with a chamber of the heart. A coronary vessel on an exterior of the heart wall is severed into a proximal portion and a distal portion. The distal portion of the vessel is placed into the vessel opening of the conduit. An alternative embodiment places the vessel flush with the vessel opening of the conduit.
摘要翻译：经心肌植入物包括穿过心壁插入的中空导管。导管限定心室开口和容器开口之间的血流路径。导管的心室开口放置成与心脏的腔室连通。心壁外部的冠状动脉血管切断到近端部分和远端部分。将容器的远端部分放置在导管的容器开口中。替代实施例将容器与管道的容器开口平齐。

36. 发明授权

US5944019A Closed chest coronary bypass 失效
标题翻译：闭合胸部冠状动脉旁路
公开(公告)号：US5944019A
公开(公告)日：1999-08-31
申请号：US882397
申请日：1997-06-25
申请人： Mark B. Knudson , William L. Giese
发明人： Mark B. Knudson , William L. Giese
IPC分类号： A61B17/00 , A61B17/11 , A61B17/12 , A61B17/34 , A61B18/24 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/90
CPC分类号： A61B17/11 , A61B17/12045 , A61B17/12131 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/2493 , A61F2/856 , A61F2/90 , A61F2/954 , A61F2/958 , A61B17/12022 , A61B17/3415 , A61B18/24 , A61B2017/00243 , A61B2017/00247 , A61B2017/1107 , A61B2017/1135 , A61B2017/12127 , A61B2018/00392 , A61F2002/061 , A61F2002/065 , A61F2002/068 , A61F2002/821 , A61F2240/008 , Y10S623/903
摘要： A method and apparatus for performing coronary artery bypass surgery establishes a channel leading directly from a chamber of a heart into a coronary artery with said channel retained open during both diastole and systole. The coronary artery bypass procedure may be performed with or without cardiopulmonary bypass.
摘要翻译：用于进行冠状动脉旁路手术的方法和装置建立了直接从心室引导到冠状动脉的通道，所述通道在舒张期和收缩期间保持打开。冠状动脉旁路手术可以在有或没有体外循环的情况下进行。

37. 发明授权

US5908029A Coronary artery bypass with reverse flow 失效
标题翻译：冠状动脉搭桥逆流
公开(公告)号：US5908029A
公开(公告)日：1999-06-01
申请号：US915539
申请日：1997-08-15
申请人： Mark B. Knudson , Katherine S. Tweden
发明人： Mark B. Knudson , Katherine S. Tweden
IPC分类号： A61F2/06 , A61B19/00
CPC分类号： A61F2/06
摘要： An obstructed coronary artery is bypassed by forming a first blood flow path from a left ventricle of the heart to a coronary vein associated with the obstructed coronary artery. A second blood flow path is formed form the obstructed coronary artery to the right ventricle for blood to flow from the left ventricle through the coronary vein to the myocardium and subsequently through the coronary artery to the right ventricle in a blood flow direction opposite a normal blood flow direction in the coronary artery and coronary vein.
摘要翻译：通过形成从心脏的左心室到与阻塞的冠状动脉相关的冠状静脉的第一血流路径来绕过阻塞的冠状动脉。形成从右心室阻塞的冠状动脉到第二血流路，血液从左心室通过冠状静脉流动到心肌，随后通过与正常血液相反的血流方向的冠状动脉通向右心室冠状动脉和冠状静脉的流动方向。

38. 发明授权

US5755682A Method and apparatus for performing coronary artery bypass surgery 失效
标题翻译：用于执行冠状动脉旁路手术的方法和装置
公开(公告)号：US5755682A
公开(公告)日：1998-05-26
申请号：US689773
申请日：1996-08-13
申请人： Mark B. Knudson , William L. Giese
发明人： Mark B. Knudson , William L. Giese
IPC分类号： A61B17/00 , A61B17/11 , A61B17/12 , A61B17/34 , A61B18/24 , A61F2/02 , A61F2/06 , A61F2/24 , A61F2/82 , A61F2/90 , A61F2/04
CPC分类号： A61B17/11 , A61B17/12045 , A61B17/12131 , A61F2/06 , A61F2/064 , A61F2/07 , A61F2/2493 , A61F2/856 , A61F2/90 , A61F2/954 , A61F2/958 , A61B17/12022 , A61B17/3415 , A61B18/24 , A61B2017/00243 , A61B2017/00247 , A61B2017/1107 , A61B2017/1135 , A61B2017/12127 , A61B2018/00392 , A61F2002/061 , A61F2002/065 , A61F2002/068 , A61F2002/821 , A61F2240/008 , Y10S623/903
摘要： A method and apparatus for performing coronary artery bypass surgery establishes a channel leading directly from a chamber of a heart into a coronary artery. The coronary artery bypass procedure may be performed with or without cardiopulmonary bypass.
摘要翻译：用于进行冠状动脉旁路手术的方法和装置建立了直接从心室引导到冠状动脉的通道。冠状动脉旁路手术可以在有或没有体外循环的情况下进行。

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