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    • 38. 发明授权
    • Process to produce tetrabromobisphenol with the reduced formation of
alkyl bromide by-products
    • 生产四溴双酚同时还原形成烷基溴副产物的方法
    • US5475153A
    • 1995-12-12
    • US368351
    • 1995-01-04
    • Stuart Armstrong
    • Stuart Armstrong
    • C07C37/62C07C39/367
    • C07C37/62
    • A process for the preparation of 4,4'-isopropylidene bis(2,6-dibromophenol), also known as tetrabrombisphenol A, that dramatically reduces the formation of alkyl bromide by-products. Bisphenol A is brominated with a C.sub.3 to C.sub.5 n-alcohol in a water mixture to suppress the formation of alkyl bromides. The bisphenol A is brominated between 15.degree. C. and 25.degree. C. and then heated at a 55.degree. C. to 70.degree. C. to insure bromination is complete. The tetrabrombisphenol A is then filtered from the reaction mixture and dried. Tetrabromobisphenol A produced from this process typically has a melting point of 180.degree. C. or higher, and is typically greater than 98% pure. Hydrogen peroxide is optionally combined with the reactants to reduce the amount of added bromine necessary for the bromination of the tetrabromobisphenol A.
    • 制备4,4'-异亚丙基双(2,6-二溴苯酚)(也称为四溴双酚A)的方法,其显着降低了烷基溴副产物的形成。 双酚A在水混合物中用C 3至C 5正构醇溴化以抑制烷基溴的形成。 双酚A在15℃和25℃之间溴化,然后在55℃加热至70℃以确保溴化完成。 然后将四溴双酚A从反应混合物中过滤并干燥。 由该方法生产的四溴双酚A通常具有180℃或更高的熔点,并且通常大于98%纯度。 任选地将过氧化氢与反应物组合以减少溴化四溴双酚A所需的溴的量。