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    • 29. 发明授权
    • Fluorescent whitening agents
    • 荧光增白剂
    • US06464735B2
    • 2002-10-15
    • US09766984
    • 2001-01-22
    • Peter RohringerGeorges MetzgerDieter Reinehr
    • Peter RohringerGeorges MetzgerDieter Reinehr
    • C07D25100
    • C09B23/148C07D251/68C11D3/42D06L4/621D06L4/657D06L4/75D06M13/07D06M13/358D06P1/6426D21H21/30Y10S8/919
    • The present invention provides new compounds having the formula: in which X is O or, preferably, NH; M is hydrogen, an alkali metal atom, ammonium or a cation formed from an amine; each R1, independently, is an aminoacid residue from which a hydrogen atom on the amino group has been removed; n is 1 or 2; and each R2, independently, is hydrogen, C1-C3alkyl, halogen, cyano, COOR in which R is hydrogen or C1-C3alkyl, CONH—R in which R has its previous significance, SO2NH—R in which R has its previous significance, NH—COR in which R has its previous significance, SO3M in which M has its previous significance or, when n is 1, R2 can also be CO—R3 in which R3 is C1-C3alkyl or phenyl; provided that those compounds are excluded in which a) X is NH, n is 1 and R2 is SO3M in which M has its previous significance; or b) X is NH, n is 2 and one R2 is SO3M in which M has its previous significance, and the other R2 is hydrogen, methyl or halogen; or c) X is NH, n is 1, R1 is glycine and R2 is H or CO2H; or d) X is NH, n is 2, each R2 is SO3M in which M has its previous significance and the SO3M groups are in 2,5-positions in the phenyl ring and R1 is D,L-alanine, L-valine, L-leucine, L-isoleucine, L-threonine, L-aspartic acid, L-glutamic acid, L-phenylalanine, L-proline, (),L- or glycine. Most of the new class of 4,4′-diaminostilbene-2,2′-disulfonic acid compounds are useful as fluorescent whitening agents, especially for paper.
    • 本发明提供了新的具有下式的化合物:其中X为O或优选为NH; M是氢,碱金属原子,铵或由胺形成的阳离子; 每个R 1独立地是氨基酸被除去的氨基酸残基; n为1或2; 并且每个R 2独立地是氢,C 1 -C 3烷基,卤素,氰基,其中R是氢或C 1 -C 3烷基的COOR,其中R具有其先前含义的CONH-R,其中R具有其先前含义的SO 2 NH- 其中R具有其先前意义的NH-COR,其中M具有其先前含义的SO 3 M,或当n为1时,R 2也可以是其中R 3为C 1 -C 3烷基或苯基的CO-R 3;条件是将这些化合物排除在 哪一个)X是NH,n是1,R2是SO3M,其中M具有其先前的意义; 环)X是NH,n是2,一个R2是SO3M,其中M具有其先前的意义,另一个R 2是氢,甲基或卤素; orc)X是NH,n是1,R1是甘氨酸,R2是H或CO2H; ord)X是NH,n是2,每个R2是SO3M,其中M具有其先前的意义,SO3M基团在苯环中是2,5位,R1是D,L-丙氨酸,L-缬氨酸,L L-亮氨酸,L-异亮氨酸,L-苏氨酸,L-天冬氨酸,L-谷氨酸,L-苯丙氨酸,L-脯氨酸,(),L-或甘氨酸。 大多数新类的4,4'-二氨基芪-2,2'-二磺酸化合物可用作荧光增白剂,特别是用于纸。