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    • 26. 发明授权
    • Process for the gelatin coating of medicaments
    • 药物明胶包衣的方法
    • US6126987A
    • 2000-10-03
    • US274761
    • 1999-03-23
    • Jeffrey D. BrehautLinn C. HooverThomas KucharskiThomas C. ReiterDavid J. RevelleDaniel A. SlaterLuis R. TorresPatrick Vo
    • Jeffrey D. BrehautLinn C. HooverThomas KucharskiThomas C. ReiterDavid J. RevelleDaniel A. SlaterLuis R. TorresPatrick Vo
    • A61J3/06A23G3/24A23G7/00A61J3/00B05B15/12B05C3/10B65D1/36A61J3/07B05C3/09
    • A23G7/0025A23G3/24A61J3/005B65D1/36B05B15/1207B05C3/10Y10S53/90
    • A process and apparatus for the gelatin coating of medicaments which includes a continuous conveyer system to advance a plurality of pallets through a loading station, at least one dipping station, at least one dryer station, a reorientation station and an unloading station. Medicaments to be coated are loaded into pallets at the loading station and advanced to the first dipping station where a vacuum is applied to secure the medicament to the pallet. The pallet is inverted and a first portion of each of the medicaments is dipped into a coating mixture. The pallet is then returned to its upright position, the vacuum is removed and the coating is dried. The medicaments are then transferred from the first pallet to a second pallet by a reorientation mechanism. The second pallet is then advanced to a second dipping station which operates in the same manner as the first dipping station. The second pallet is advanced through the dryer station and the fully coated medicaments are ejected from the pallet into a container. The pallets used to hold the medicaments include a plate-like support member, on which rests a flexible mat having a rectangular array of receptacles including compliant diaphragm portions such that when a vacuum is applied to the pallet, the medicaments are secured thereto. The drying means includes air directing plates having sinusoidal rows of air directing apertures under which the medicaments to be dried are passed.
    • 用于药物明胶涂层的方法和装置,其包括连续输送系统,以通过装载站,至少一个浸渍站,至少一个干燥站,重新定向站和卸载站推进多个托盘。 待涂覆的药物装载在装载站的托盘中并且前进到第一浸渍站,在那里施加真空以将药剂固定到托盘上。 托盘倒置,每个药物的第一部分浸入涂料混合物中。 然后将托盘返回到其直立位置,除去真空并将涂层干燥。 然后通过重新定向机构将药物从第一托盘转移到第二托盘。 然后将第二托盘推进到以与第一浸渍站相同的方式操作的第二浸渍站。 第二个托盘通过干燥站前进,完全涂覆的药物从托盘中排出到容器中。 用于保持药物的托盘包括板状支撑构件,其上放置有具有矩形阵列的容器的柔性垫,其包括顺应性膜部分,使得当将真空施加到托盘时,药物被固定到其上。 干燥装置包括具有正弦排的空气引导孔的空气引导板,待干燥的药物在该空气引导孔下通过。