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    • 22. 发明公开
    • METHOD OF JUDGING MISMATCH BETWEEN SINGLE−STRANDED NUCLEIC ACID MOLECULES
    • VERFAHREN ZUR BEURTEILUNG EINER FEHLPAARUNG ZWISCHENEINZELSTRÄNGIGENNUKLEINSÄUREMOLEKÜLEN
    • EP1428890A1
    • 2004-06-16
    • EP02762825.4
    • 2002-08-22
    • The Circle for the Promotion of Science and EngineeringNOF CORPORATION
    • MARUYAMA, Atsushi, c/o TOKYO INST. OF TECHNOLOGY
    • C12Q1/68C12N15/09
    • C12Q1/6832C12Q1/6827C12Q2537/113C12Q2527/125
    • There is provided a method for judging whether or not a sequence mismatch or mismatches occur between a sample single-stranded nucleic acid molecule and a standard single-stranded nucleic acid molecule, comprising: allowing a double-stranded nucleic acid molecule consisting of the standard single-stranded nucleic acid molecule and a complementary strand thereof to co-exist with the sample single-stranded nucleic acid molecule in the presence of a cationic polymer; determining the ratio of the substation of the complementary strand of the standard single-stranded nucleic acid molecule:by the sample single-stranded nucleic acid molecule; and judging whether or not a sequence mismatch or mismatches occur between the two molecules based on the value determined. The method makes it possible to discriminate the occurrence of a sequence mismatch between single-stranded nucleic acid molecules accurately even when the mismatch occurs only in a single base.
    • 提供了用于判断样品单链核酸分子与标准单链核酸分子之间是否发生序列错配或错配的方法,包括:允许由标准单链核酸分子组成的双链核酸分子 标记的核酸分子及其互补链与样品单链核酸分子在阳离子聚合物的存在下共存; 确定标准单链核酸分子的互补链的分支的比例:样品单链核酸分子; 并基于所确定的值判断两个分子之间是否发生序列错配或错配。 该方法即使在仅在单个碱基中发生失配时也能够准确地区分单链核酸分子之间的序列错配的发生。
    • 24. 发明授权
    • Method for creating high resolution color image, system for creating high resolution color image and program creating high resolution color image
    • 创建高分辨率彩色图像的方法,用于创建高分辨率彩色图像的系统和创建高分辨率彩色图像的程序
    • US07515747B2
    • 2009-04-07
    • US10543846
    • 2003-10-08
    • Masatoshi OkutomiTomomasa Goto
    • Masatoshi OkutomiTomomasa Goto
    • G06K9/00
    • H04N9/045H04N2209/046
    • A limitation in the physical resolution of an image sensor offers a motivation to improve the resolution of an image. Super-resolution is mainly applied to gray scale images, and it has not been thoroughly investigated yet that a high resolution color image is reconstructed from an image sensor having a color filter array. An object of the invention is to directly reconstruct a high resolution color image from color mosaic obtained by an image sensor having a color filter array. A high resolution color image reconstruction method according to the invention is based on novel technique principles of color image reconstruction that an increase in resolution and demosaicing are performed at the same time. The verification and effective implement of the invention are also described.
    • 图像传感器的物理分辨率的限制提供了提高图像分辨率的动机。 超分辨率主要应用于灰度图像,并且尚未深入研究,从具有滤色器阵列的图像传感器重构高分辨率彩色图像。 本发明的目的是通过具有滤色器阵列的图像传感器直接重建由彩色马赛克获得的高分辨率彩色图像。 根据本发明的高分辨率彩色图像重建方法基于彩色图像重建的新技术原理,其同时执行分辨率和去马赛克的增加。 还描述了本发明的验证和有效实施。
    • 27. 发明申请
    • Nonlinear Controller and Nonlinear Control Method
    • 非线性控制器与非线性控制方法
    • US20070282464A1
    • 2007-12-06
    • US10588770
    • 2005-02-01
    • Yoshihiro Miyake
    • Yoshihiro Miyake
    • G05B13/02
    • G05B13/02G05B2219/40414G05B2219/45108
    • An object of the present invention is to provide a novel controller and a control method which, in a nonlinear system in which a controller 1 and a controlled object 2 cannot be clearly separated, can converge the relationship between the controller 1 and controlled object 2 to a target relationship. The controller 1 of the present invention comprises a first module 3 having dynamic behavior as a nonlinear system and a second module 4 as a feedback system. The first module 3 creates a synchronous state with the controlled object 2 through an entrainment effect in an interaction therewith. When a synchronous state is created between the first module 3 and the controlled object 2, the second module 4 provides feedback to adjust a parameter of the first module 3 based on the difference between a relation value 5 relating to the synchronization and a target relation value. The controlled object 2 is controlled by the convergence of the relation value 5 relating to the synchronization to the target value.
    • 本发明的目的是提供一种新颖的控制器和控制方法,其中控制器1和受控对象2不能清楚地分离的非线性系统中,可以将控制器1和受控对象2之间的关系收敛到 目标关系。 本发明的控制器1包括具有作为非线性系统的动态特性的第一模块3和作为反馈系统的第二模块4。 第一模块3通过与其相互作用的夹带效应与受控对象2产生同步状态。 当在第一模块3和受控对象2之间创建同步状态时,第二模块4基于与同步关系的关系值5与目标关系值之间的差异提供反馈以调整第一模块3的参数 。 受控对象2由与该同步关系的关系值5的收敛控制为目标值。
    • 28. 发明申请
    • Method for measuring optical-phase distribution
    • 光学相位分布测量方法
    • US20060187467A1
    • 2006-08-24
    • US11359126
    • 2006-02-21
    • Kenji AmayaMasashi Ueshima
    • Kenji AmayaMasashi Ueshima
    • G01B11/24
    • G01B11/2441G01J9/00G01M11/0228
    • A provided optical-phase-distribution measuring method, by which optical phase distribution is identified at high speed and with high accuracy from information on light-intensity distribution without using a special measuring device, comprises steps: for inputting light to be measured to optical systems, respectively, modulating the intensity and the phase, detecting the output light to be measured with CCD, and measuring the intensity distribution of detected light to be measured as an image with an optical-phase-distribution measuring system provided with the two different optical systems; for setting an observation equation, based on the intensity distribution and on the optical characteristics of the optical systems; for setting a phase-distribution identification inverse-problem from the observation equation, and formulating the set phase-distribution identification inverse-problem as a first nonlinear optimization problem in which complex amplitude representing the light to be measured is assumed to be a design variable; for converting the first nonlinear optimization problem to a second nonlinear optimization problem, in which expansion coefficients in a series expansion are assumed to be design variables, by series expansion of the phase distribution of the light to be measured; and for identifying the phase distribution of the light to be measured by solving the second nonlinear optimization problem.
    • 一种提供的相位分布测量方法,其中通过光信号分布从高分辨率的信息识别光强分布而不使用特殊的测量装置,其中包括以下步骤:将要测量的光输入光学系统 分别调制强度和相位,用CCD检测要测量的输出光,并用配备有两个不同光学系统的光相位分布测量系统测量被测光的测量光的强度分布作为图像 ; 用于基于光学系统的强度分布和光学特性设置观测方程; 用于从观测方程设定相位分布识别反问题,并且将所设定的相位分布识别反问题作为第一非线性优化问题,其中假定表示待测光的复数幅度为设计变量; 用于将第一非线性优化问题转换为第二非线性优化问题,其中串联扩展中的膨胀系数被假设为设计变量,通过对待测量的光的相位分布进行串联扩展; 并且通过求解第二非线性优化问题来识别要测量的光的相位分布。
    • 29. 发明申请
    • WALKING AID SYSTEM
    • 行车辅助系统
    • US20110166488A1
    • 2011-07-07
    • US11576645
    • 2005-10-05
    • Yoshihiro Miyake
    • Yoshihiro Miyake
    • A61H1/02
    • A61B5/112A61B5/1124A61B5/4082A61H3/00A61H2230/00A61H2230/06A61H2230/08
    • An object of the present invention is to realize mutual adaptation for mutual synchronizing in a man-machine system and make it applicable to the site of walking aid. A walking aid system of the present invention comprises: a sensor section (2) for sensing the motion rhythm of a walker, a recording section (33) for recording values of measurements of the motion rhythm sensed with the sensor section 2, a target setting section (34) for setting a target value for the motion rhythm of the walker, a timing generating section (36) for generating a timing signal according to the difference between the measurement and the target value, and a stimulus generating section (4) for generating rhythm stimulus that is recognizable by the walker, according to the timing signal generated with the timing generating section (36).
    • 本发明的目的是在人机系统中实现相互同步的相互适应,并使其适用于步行辅助部位。 本发明的步行辅助系统包括:用于感测步行者的运动节奏的传感器部分(2),用于记录用传感器部分2感测的运动节奏的测量值的记录部分(33),目标设定 用于设置步行者的运动节奏的目标值的部分(34),用于根据测量值和目标值之间的差异产生定时信号的定时产生部分(36),以及用于 根据由定时产生部分(36)产生的定时信号产生可由步行者识别的节奏刺激。