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21. 发明专利

JPH03501087A 失效
公开(公告)号：JPH03501087A
公开(公告)日：1991-03-14
申请号：JP50683588
申请日：1988-07-15
申请人： SQUIBB & SONS INC
IPC分类号： A61B19/00 , A61M25/01 , A61M25/02 , A61M25/08

22. 发明专利

JPH02261448A COUPLING FOR ARITIFICAL ANAL 失效
公开(公告)号：JPH02261448A
公开(公告)日：1990-10-24
申请号：JP2500190
申请日：1990-02-02
申请人： SQUIBB & SONS INC
发明人： PIITAA RESURII SUTEA , DEBITSUDO JIYON OURUDO
IPC分类号： A61F5/448
摘要： PURPOSE: To obtain a safe lock system by setting up so that the shape and the mounting position of an arm so as to deform the seam in the radial inside direction when a locking material rotates against a body-side coupling element, and overlaid on a part of a bag-side coupling element. CONSTITUTION: A coupling system for an artificial anus bag consists of a bag- side coupling element 100, a body-side coupling element 200 and a locking member 300. In order to assemble the locking member 300 in the body-side coupling element 200, a rib-shaped member 204 is inserted in an opening 302 for small hole formed by an inner face 314 of a blade part 310, and a roof part 212 of the lug 210 is crossed with the lower side of the blade part 310 to bend upward. In this case, the lug 210 may be installed between the blade part 310 corresponding to one arm 306 and the leg part of an obliquely adjacent arm. After the lock member 300 and the body-side coupling element 200 are assembled, a rib- shaped member 204 is inserted into a grooved member 104, and finally snap- interfits the bag-side coupling element 100.

23. 发明专利

JPH02221278A 7-OXABICYCLOHEPTYL-SUBSTITUTED HETEROCYCLIC AMIDEPROSTAGLANDIN ANLOGUE 失效
公开(公告)号：JPH02221278A
公开(公告)日：1990-09-04
申请号：JP33803389
申请日：1989-12-25
申请人： SQUIBB & SONS INC
发明人： FUIRITSUPU EMU SHIYAA , FUIRITSUPU DEII SUTEIN , DEBITSUDO FUROIDO , SUTEIIBUN II HOORU
IPC分类号： A61K31/34 , A61K31/557 , A61P7/02 , A61P11/08 , A61P43/00 , C07C45/29 , C07D493/08

24. 发明专利

JPH0237345B2 失效
公开(公告)号：JPH0237345B2
公开(公告)日：1990-08-23
申请号：JP21607581
申请日：1981-12-23
申请人： SQUIBB & SONS INC
发明人： ADORIAN NAN , MITSUSHERU ROBEEGU
IPC分类号： A61K31/165 , A61K31/19 , A61K51/00 , A61K51/04 , C07C237/04 , C07C237/06

25. 发明专利

JPH02109560A IMPROVED BANDAGE 失效
公开(公告)号：JPH02109560A
公开(公告)日：1990-04-23
申请号：JP23453189
申请日：1989-09-08
申请人： SQUIBB & SONS INC
发明人： OURI ROJIYAA JIENSEN
IPC分类号： A61F13/00 , A61F13/02 , A61F13/15 , A61L15/58
摘要： PURPOSE: To make a bandage with excellent absorption and retention, and keep good contact with skin even when curved against the skin, by wrapping a super-absorbing pad with a nonwoven fabric sheet, fastening it with an acrylic adhesive to a side of a base material, and edging the pad with the adhesive. CONSTITUTION: A pad material is punched into a square pad and placed on a nonwoven fabric sheet 20, the same material as the sheet 10, Then, the super- absorbing pad 18 is wrapped with the nonwoven fabric sheet 20, where the flaps 20a and 20b are overlapped and folded neatly. Then, the both sides of the pad unit is crimped along a line 22, cut and sealed. The wrapped pad (the flaps are folded but not sealed) is placed at the center of the adhesive-coated base B, and firmly stuck to a plastic film 12. The adhesive layer 16 keeps unsealed flaps 20a, 20b in a sealed state. The super-absorbing pad 18 is encompassed by an edging of skin-sticking adhesive layers 11, 16.

26. 发明专利

JPH02108635A COMPOSITION FOR PREVENTING AND TREATING SKIN DAMAGE 失效
公开(公告)号：JPH02108635A
公开(公告)日：1990-04-20
申请号：JP22817889
申请日：1989-08-31
申请人： SQUIBB & SONS INC
发明人： ROORENSU TEII FURIIDOHOFU , ROORA ERU BORUTON
IPC分类号： A61K31/00 , A61K31/19 , A61K31/195 , A61K31/557 , A61K45/00 , A61P3/00 , A61P17/00
摘要： PURPOSE: To prepare the subject composition, comprising a thromboxane A2 receptor antagonist as an active ingredient and capable of promoting the curing of skin injuries and/or limiting the degree of the injuries. CONSTITUTION: This composition comprises a thromboxane A2 antagonist, e.g. 7-oxabicycloheptane-substituted diamidoprostaglandin analog, a phenoxyalkylcarboxylic acid, a sulfonamidophenylcarboxylic acid or an arylthioalkylphenylcarboxylic acid as an active ingredient. The resultant composition is systemically or locally administered to skin during or after suffering thereof from a heat burn or a trauma or before or during or after suffering thereof from pressure injuries (e.g. a decubitus) when the skin suffers therefrom. The daily dose thereof is 5-2,500mg, preferably 10-2,000mg in the case of a systemic dosage form.

27. 发明专利

JPH0291057A ARYLCYANOGUANIDINES BEING CALCIUM TUBE ACTIVATOR AND PRODUCTION THEREOF 失效
公开(公告)号：JPH0291057A
公开(公告)日：1990-03-30
申请号：JP20658289
申请日：1989-08-09
申请人： SQUIBB & SONS INC
发明人： KAANEIRU ESU ATSUUORU , JIYON AARU MATSUKAROU , GEIRII JIEI GUROOBAA
IPC分类号： C07D405/00 , A61K31/40 , A61K31/44 , A61K31/443 , A61K31/455 , A61K31/505 , A61P9/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P21/02 , A61P25/04 , C07C277/00 , C07C279/28 , C07C317/42 , C07C323/35 , C07C323/65 , C07D217/24 , C07D295/18 , C07D405/04

28. 发明专利

JPH02780A PURINYL AND PYLIMIDINYLCYCLOBUTANE 失效
公开(公告)号：JPH02780A
公开(公告)日：1990-01-05
申请号：JP33269388
申请日：1988-12-28
申请人： SQUIBB & SONS INC
发明人： ROBAATO ZAARAA , GUREN ANSONII JIYAKOBUSU
IPC分类号： C07D239/47 , A61K31/435 , A61K31/505 , A61K31/52 , A61K31/522 , A61K31/53 , A61K31/675 , A61P31/12 , C07D239/46 , C07D239/54 , C07D239/553 , C07D303/22 , C07D305/06 , C07D471/04 , C07D473/00 , C07D473/16 , C07D473/18 , C07D473/30 , C07D473/32 , C07D473/34 , C07D473/40 , C07D487/04 , C07F9/6561

29. 发明专利

JPH02284A PREPARATION OF 2-OXO-1-((SUBSTITUTED SULFONYL)AMINO)CARBONYL)AZETIDINE AND INTERMEDIATE USED THEREFOR 失效
公开(公告)号：JPH02284A
公开(公告)日：1990-01-05
申请号：JP32320588
申请日：1988-12-21
申请人： SQUIBB & SONS INC
发明人： JIYORII DEII GODOFURII JIYUNIA , RICHIYAADO EICHI MIYUURAA , ROBAATO ZAARAA
IPC分类号： C07D205/085 , A61K31/397 , A61K31/44 , A61K31/4427 , A61K31/55 , A61P31/04 , C07D213/79 , C07D401/12 , C07D401/14 , C07D417/12 , C07D417/14

30. 发明专利

JPH01317436A COUPLING FOR ARTIFICIAL ANUS 失效
公开(公告)号：JPH01317436A
公开(公告)日：1989-12-22
申请号：JP9620989
申请日：1989-04-14
申请人： SQUIBB & SONS INC
发明人： PIITAA RESURII SUTEA , NEIRU FUIRITSUPU UIRUTSUSHIYAA
IPC分类号： A61F5/448
摘要： PURPOSE: To attach and detach two coupling elements without applying pressure or tensile force on an user by bonding the flat surfaces of tapered member and a clamp means to allow them to face each other in the clamp means. CONSTITUTION: A coupling element 20 at a bag side attached with an artificial anus bag is engaged with an external coupling element 40 applied on user's body by means of a medical grade adhesive pad, to bring flat surfaces 47 and 27 in contact. Then, a clamp means 60 is engaged and wound to circumferential flanges of members 28 and 48, and engaged by a hook 67 with a catch 68 to close. The clamp means 60 thus bonds two coupling elements 20 and 40, but any force is not applied by a clamping pressure against such a vulnerable area around the small hole as touching may hurt because of arrangements of the tapered U shape grooves of the part 28 and 48. Furthermore, a seal strip 46 works together with a rim 23 of a shooting part 22, to give a reliable and efficient sealing and prevent liquid from escaping.

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