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21. 发明授权

EP2489379B1 Intradermal pen adapter 有权转让
公开(公告)号：EP2489379B1
公开(公告)日：2020-09-23
申请号：EP12151596.9
申请日：2012-01-18
申请人： SID Technologies, LLC
发明人： Tsals, Izrail , Evans, Christopher , Costello, Brian
IPC分类号： A61M5/158 , A61M5/32 , A61M5/46 , A61B5/15 , A61B5/153

22. 发明公开

EP2750737A1 SUBCUTANEOUS AND INTRADERMAL PATCH INFUSERS 审中-公开
标题翻译：皮下和皮内石膏输液设备
公开(公告)号：EP2750737A1
公开(公告)日：2014-07-09
申请号：EP12755937.5
申请日：2012-08-23
申请人： Sid Technologies LLC
发明人： TSALS, Izrail
IPC分类号： A61M5/20 , A61M5/145
CPC分类号： A61M5/158 , A61M5/14248 , A61M5/1454 , A61M5/1456 , A61M2005/14256 , A61M2005/14513 , A61M2005/1581 , A61M2005/1585
摘要： The device infuses a compound subcutaneously or intradermally over an extended period of time. The delivery is from a conventional prefilled syringe with a staked cannula with the device adhered to the injection site and the syringe positioned substantially parallel to the injection site. The cannula is formed by a mechanism integral to the device to provide the cannula distal section substantially perpendicular to the syringe axis. The compound delivery is based on springs or other mechanisms. The approach offers a low cost mechanical system for the infusion of high volume, viscous compounds. The activation of the patch infuser required a few simple steps by the user. A single lever is used to trigger all device functions.

23. 发明授权

EP2373365B1 ALIGNMENT OF A NEEDLE IN AN INTRADERMAL INJECTION DEVICE 有权
标题翻译：针的IN A皮内注射单位取向
公开(公告)号：EP2373365B1
公开(公告)日：2014-04-23
申请号：EP09771818.3
申请日：2009-12-07
申请人： Sid Technologies LLC , Program for Appropriate Technology in Health
发明人： TSALS, Izrail , HARVEY, Darrell
IPC分类号： A61M5/32 , A61M5/42 , A61M5/46
CPC分类号： A61M5/3287 , A61M5/3216 , A61M5/425 , A61M5/46

24. 发明公开

EP2139543A1 METHODS AND DEVICES FOR INTRADERMAL INJECTION 有权转让
标题翻译：方法和设备皮内注射
公开(公告)号：EP2139543A1
公开(公告)日：2010-01-06
申请号：EP08746707.2
申请日：2008-04-23
申请人： Sid Technologies Llc , Program for Appropriate Technology in Health
发明人： TSALS, Izrail
IPC分类号： A61M5/32
CPC分类号： A61M5/46 , A61M5/3243 , A61M5/3271 , A61M5/3287 , A61M5/425 , A61M2005/3247
摘要： Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.

25. 发明授权

EP2139543B1 DEVICES FOR INTRADERMAL INJECTION 有权转让
公开(公告)号：EP2139543B1
公开(公告)日：2018-06-06
申请号：EP08746707.2
申请日：2008-04-23
申请人： Sid Technologies LLC , Program for Appropriate Technology in Health
发明人： TSALS, Izrail
IPC分类号： A61M5/32 , A61M5/46 , A61M5/42
CPC分类号： A61M5/46 , A61M5/3243 , A61M5/3271 , A61M5/3287 , A61M5/425 , A61M2005/3247
摘要： Devices and methods for intradermal (ID) administration of diagnostic and therapeutic agents, vaccines and other compounds into the dermal layer of the skin are disclosed. The devices and the methods simplify the ID injection process and increase the consistency of the placement of the needle tip in the dermal space close to the skin surface allowing for a shallow cannula placement in the dermis. Furthermore, the devices and methods broaden the number of sites suitable for ID injection and make the ID injection possible with limited training.

26. 发明公开

EP2456491A1 INTRADERMAL INJECTION ADAPTER 有权
标题翻译： INTRADERMALER INJEKTIONSADAPTER
公开(公告)号：EP2456491A1
公开(公告)日：2012-05-30
申请号：EP10739767.1
申请日：2010-07-23
申请人： Sid Technologies LLC
发明人： TSALS, Izrail
IPC分类号： A61M5/46
CPC分类号： A61M5/46 , A61M5/321 , A61M5/3216 , A61M5/3287
摘要： An intradermal injection assembly for injecting a medicament into skin could form an intradermal needle with an adapter, an intradermal syringe with an adapter or an adapter for a merger with a syringe with a cannula. The intradermal adapter in these devices has a body having a longitudinal axis, a central portion having a cannula channel and a distal protrusion extending generally parallel to the longitudinal axis. The distal protrusion of the adapter has a first skin contacting surface extending generally parallel to the longitudinal axis. At least a portion of the distal protrusion is generally transparent such that the portion of the cannula that extends distally relative to a demarcation plane can be viewed through the distal protrusion during insertion of the cannula into a patient's skin.
摘要翻译：用于将药物注射到皮肤中的真皮内注射组件可以形成具有适配器的皮内针，具有适配器的皮内注射器或用于与具有插管的注射器并入的适配器。这些装置中的真皮内适配器具有具有纵向轴线的主体，具有套管通道的中心部分和大致平行于纵向轴线延伸的远端突出部。适配器的远端突起具有大致平行于纵向轴线延伸的第一皮肤接触表面。远侧突起的至少一部分通常是透明的，使得在将套管插入患者皮肤期间，套管的相对于分界平面向远侧延伸的部分可以通过远侧突出部分观察。

27. 发明公开

EP1814616A1 AUTOMATIC INJECTOR 审中-公开
标题翻译：自动注射器
公开(公告)号：EP1814616A1
公开(公告)日：2007-08-08
申请号：EP05823247.1
申请日：2005-11-04
申请人： Sid Technologies Llc
发明人： TSALS, Izrail , LAVI, Gilad
IPC分类号： A61M5/20
CPC分类号： A61M5/2033 , A61M5/3204 , A61M5/326 , A61M2005/206 , A61M2005/2073 , A61M2005/3247 , A61M2205/59
摘要： An injector is automatic in that the needle insertion into the injection site (e.g., a patient's skin) is triggered by the user or caregiver, the insertion is automatic, the following delivery is automatically initiated upon needle insertion, and the needle is shielded automatically after the end of delivery. Preferably the user does not see the needle prior to, during, or after injection. The injector includes a proximal and distal housings and a needle shield arranged to slide on the distal housing. The injector has a driver arranged to move the syringe to cause the needle penetration, to inject the drug, and subsequently to release the shield. The syringe needle is shielded and the shield locked automatically after delivery is completed. The patient does not experience any injector force on the tissue during injection. The injector has built in patient safety features.
摘要翻译：注射器是自动的，因为注射部位（例如，患者的皮肤）的针插入由使用者或看护者触发，插入是自动的，在插入针时自动启动下面的输送，并且针自动屏蔽交付的结束。优选地，使用者在注射之前，注射期间或之后不会看到针头。该注射器包括近端壳体和远端壳体以及布置成在远端壳体上滑动的针护罩。注射器具有驱动器，该驱动器布置成移动注射器以引起针穿刺，注射药物，并随后释放护罩。输送完成后，注射器针头被屏蔽并自动锁定护罩。在注射期间，病人在组织上没有经历任何注射器力。注射器内置了患者安全功能。

28. 发明申请

US20140194854A1 SUBCUTANEOUS AND INTRADERMAL PATCH INFUSERS 审中-公开
标题翻译：婴幼儿和肛门输卵管
公开(公告)号：US20140194854A1
公开(公告)日：2014-07-10
申请号：US14240902
申请日：2012-08-23
申请人： Izrail Tsals
发明人： Izrail Tsals
IPC分类号： A61M5/158
CPC分类号： A61M5/158 , A61M5/14248 , A61M5/1454 , A61M5/1456 , A61M2005/14256 , A61M2005/14513 , A61M2005/1581 , A61M2005/1585
摘要： The device infuses a compound subcutaneously or intradermally over an extended period of time. The delivery is from a conventional prefilled syringe with a staked cannula with the device adhered to the injection site and the syringe positioned substantially parallel to the injection site. The cannula is formed by a mechanism integral to the device to provide the cannula distal section substantially perpendicular to the syringe axis. The compound delivery is based on springs or other mechanisms. The approach offers a low cost mechanical system for the infusion of high volume, viscous compounds. The activation of the patch infuser required a few simple steps by the user. A single lever is used to trigger all device functions.
摘要翻译：该装置在长时间内皮下或皮内注入化合物。该传送来自具有插入式插管的常规预充式注射器，该装置将该装置粘附到注射部位并且注射器基本上平行于注射部位定位。套管由与装置成一体的机构形成，以提供基本上垂直于注射器轴线的套管远端部分。复合输送是基于弹簧或其他机构。该方法提供了低成本的机械系统，用于输注大体积，粘稠的化合物。补丁infuser的激活需要用户简单的几个步骤。单个杆用于触发所有设备功能。

29. 发明授权

US09089655B2 Intradermal injection adapter 有权
标题翻译：皮内注射适配器
公开(公告)号：US09089655B2
公开(公告)日：2015-07-28
申请号：US13386099
申请日：2010-07-23
申请人： Izrail Tsals
发明人： Izrail Tsals
IPC分类号： A61M5/00 , A61M5/46 , A61M5/32
CPC分类号： A61M5/46 , A61M5/321 , A61M5/3216 , A61M5/3287
摘要： An intradermal injection assembly for injecting a medicament into skin could form an intradermal needle with an adapter, an intradermal syringe with an adapter or an adapter for a merger with a syringe with a cannula. The intradermal adapter in these devices has a body having a longitudinal axis, a central portion having a cannula channel and a distal protrusion extending generally parallel to the longitudinal axis. The distal protrusion of the adapter has a first skin contacting surface extending generally parallel to the longitudinal axis. At least a portion of the distal protrusion is generally transparent such that the portion of the cannula that extends distally relative to a demarcation plane can be viewed through the distal protrusion during insertion of the cannula into a patient's skin.
摘要翻译：用于将药物注射到皮肤中的真皮内注射组件可以形成具有适配器的皮内针，具有适配器的皮内注射器或用于与具有套管的注射器并入的适配器。这些装置中的真皮内适配器具有具有纵向轴线的主体，具有套管通道的中心部分和大致平行于纵向轴线延伸的远端突出部。适配器的远端突起具有大致平行于纵向轴线延伸的第一皮肤接触表面。远侧突起的至少一部分通常是透明的，使得在将插管插入患者皮肤期间，可以通过远侧突出部分观察到相对于分界平面向远侧延伸的套管部分。

30. 发明授权

US08876764B2 Intradermal pen adapter 有权
标题翻译：皮内笔适配器
公开(公告)号：US08876764B2
公开(公告)日：2014-11-04
申请号：US13355031
申请日：2012-01-20
申请人： Izrail Tsals , Christopher Evans , Brian Costello
发明人： Izrail Tsals , Christopher Evans , Brian Costello
IPC分类号： A61M5/00 , A61M5/32 , A61M5/158 , A61M5/46 , A61B5/15 , A61B5/153
CPC分类号： A61M5/46 , A61B5/150068 , A61B5/150183 , A61B5/150748 , A61B5/153 , A61M5/158 , A61M5/3287
摘要： An intradermal injection adapter includes a body having a longitudinal axis and a central portion located distally relative to the body along the longitudinal axis. The central portion has a cannula channel therethrough extending generally parallel to the longitudinal axis. A cannula within the cannula channel has a sharpened tip for injection into a patient and a sharpened opposite proximal end for injection into a pen injector. A distal protrusion has a first skin contacting surface extending generally parallel to the longitudinal axis. The first skin contacting surface is spaced from the cannula such that a distal portion of the cannula extends generally parallel to the first skin contacting surface.
摘要翻译：真皮内注射适配器包括具有纵向轴线的主体和沿着纵向轴线相对于身体向远侧定位的中心部分。中心部分具有大致平行于纵向轴线的插管通道。插管通道内的插管具有用于注入患者的尖锐尖端和用于注入笔式注射器的锐化的相对近端。远端突起具有大致平行于纵向轴线延伸的第一皮肤接触表面。第一皮肤接触表面与套管间隔开，使得套管的远端部分大致平行于第一皮肤接触表面延伸。

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