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21. 发明授权

US09877725B2 Neural prosthesis and method for producing a neural prosthesis 有权
公开(公告)号：US09877725B2
公开(公告)日：2018-01-30
申请号：US13515211
申请日：2010-12-10
申请人： Georg Bretthauer , Selman Uranues
发明人： Georg Bretthauer , Selman Uranues
IPC分类号： A61B17/08 , A61B17/11 , A61N1/05 , A61N1/36
CPC分类号： A61B17/1128 , A61N1/0551 , A61N1/36103
摘要： The invention relates to a neural prosthesis, a neural prosthesis for use in the treatment of severed nerves and to a method for producing a neural prosthesis. Said neural prosthesis comprises a coupling element receptacle and at least one coupling element having a first and a second coupling section, wherein the coupling element is fixed by the coupling element receptacle, and wherein the first coupling section can be arranged on a first nerve region and the second coupling section on a second nerve region so that both nerve regions can be coupled by means of the neural prosthesis.

22. 发明授权

US09077454B2 Optical detector for detecting optical signal beams, method to detect optical signals, and use of an optical detector to detect optical signals 有权
标题翻译：用于检测光信号光的光检测器，检测光信号的方法，以及使用光检测器检测光信号
公开(公告)号：US09077454B2
公开(公告)日：2015-07-07
申请号：US13412550
申请日：2012-03-05
申请人： Jingshi Li , Matthias Lauermann , Sven Schüle , Juerg Leuthold , Wolfgang Freude
发明人： Jingshi Li , Matthias Lauermann , Sven Schüle , Juerg Leuthold , Wolfgang Freude
IPC分类号： H04B10/61 , H04B10/60 , H04B10/67
CPC分类号： H04B10/613 , H04B10/60 , H04B10/61 , H04B10/614 , H04B10/677
摘要： An optical detector for detecting an optical signal beam (OSB) modulated in a way that it includes an in-phase and/or a quadrature component, includes: a polarization beam splitter arranged to split the OSB into two polarized OSBs; a non-polarization beam splitter arranged to further split each of the two polarized OSBs into two split polarized OSBs; at least one birefringent element providing a phase shift, the birefringent element being arranged in a path of at least one polarized OSB and/or in a path of at least one split polarized OSB so that an in-phase and quadrature phase offset between two split polarized OSBs originating from the same polarized OSB is formed in output signal beams; and at least two detection means arranged to receive at least one output signal beam that includes a in-phase and/or quadrature component of the OSB.
摘要翻译：一种光检测器，用于检测以包括同相和/或正交分量的方式调制的光信号光束（OSB），包括：偏振分束器，被布置成将OSB分割为两个极化OSB; 非偏振分束器，被布置成进一步将两个极化OSB中的每一个分成两个分离极化OSB; 提供相移的至少一个双折射元件，所述双折射元件被布置在至少一个极化OSB的路径和/或至少一个分离极化OSB的路径中，使得在两个分裂之间的同相和正交相位偏移源自相同极化OSB的极化OSB形成在输出信号光束中; 以及至少两个检测装置，被布置成接收包括所述OSB的同相和/或正交分量的至少一个输出信号波束。

23. 发明申请

US20150183826A1 CD44V6-Derived Peptides for Treating Metastasizing Cancer 有权
标题翻译：用于治疗转移性癌症的CD44V6衍生肽
公开(公告)号：US20150183826A1
公开(公告)日：2015-07-02
申请号：US14407283
申请日：2013-11-21
申请人： KARLSRUHER INSTITUT FÜR TECHNOLOGIE , AMCURE GMBH
发明人： Veronique Orian-Rousseau , Alexandra Matzke , Helmut Ponta
IPC分类号： C07K7/06 , C07K7/08
CPC分类号： C07K7/06 , A61K38/00 , A61K38/177 , C07K7/08
摘要： The present invention relates to compounds, pharmaceutical compositions and methods for treating different forms of pancreatic cancer.
摘要翻译：本发明涉及用于治疗不同形式胰腺癌的化合物，药物组合物和方法。

24. 发明申请

US20140315066A1 ELECTROLYTE BATTERIES 有权
标题翻译：电解电池
公开(公告)号：US20140315066A1
公开(公告)日：2014-10-23
申请号：US14110744
申请日：2012-04-12
申请人： Wilhelm Pfleging , Robert Kohler , Johannes Proll
发明人： Wilhelm Pfleging , Robert Kohler , Johannes Proll
IPC分类号： H01M2/18 , B23K26/00 , H01M4/13
CPC分类号： H01M2/18 , B23K26/00 , H01M4/0435 , H01M4/13 , H01M10/0525 , H01M10/0569 , H01M2004/021 , H01M2004/025 , Y02E60/122 , Y02P70/54 , Y02T10/7011 , Y10T29/49108
摘要： The invention relates to an electrolyte battery electrode component having a layer having a surface adjoined by electrolyte in the battery and provided with a fluid-conducting channel structure. In this context, it is envisaged that through the fluid-conducting structure has channels having channel depths in the range from 10 to 200 μm and/or at least 50% of the thickness of the active layer.
摘要翻译：本发明涉及一种电解质电池电极组件，其具有在电池中具有与电解质相邻的表面并具有导流通道结构的层。在本上下文中，设想通过流体导电结构具有通道深度在10至200μm范围内的通道和/或活性层厚度的至少50％。

25. 发明申请

US20140065060A1 Precursors for Metal Organic Chemical Vapor Deposition Processes and Their Use 审中-公开
标题翻译：金属有机化学气相沉积工艺及其用途的前体
公开(公告)号：US20140065060A1
公开(公告)日：2014-03-06
申请号：US14013700
申请日：2013-08-29
申请人： Karlsruher Institut fur Technologie (KIT) , BASF SE
发明人： Wolfgang Gerlinger , Bernd Sachweh , Stefan Bräse , Mirja Enders , Thierry Müller , Gerhard Kasper , Martin Seipenbusch , Kun Gao , Matthias Faust , Linus Reichenbach
IPC分类号： B01J23/42 , C07F17/02
CPC分类号： B01J23/42 , B01J31/2291 , B01J31/2295 , B01J35/002 , B01J35/004 , B01J35/0053 , B01J35/006 , B01J35/0066 , B01J37/08 , B01J37/34 , B01J2531/828 , C07F15/0086 , C07F17/02
摘要： The present invention relates to a compound of the general formula (I) wherein R1 represents a group selected from the list consisting of methyl, ethyl, n-propyl, isopropyl, n-butyl, sec-butyl, tert-butyl, linear or branched, saturated or mono- or polyunsaturated aliphatic carbon chain containing from two to ten carbon atoms, phenyl, and phenylacetylen, and wherein R2 and R3 independently of each other represent a group selected from the list consisting of Cl, I, methyl, phenyl, or phenylacetylene.
摘要翻译：本发明涉及通式（I）的化合物，其中R 1表示选自甲基，乙基，正丙基，异丙基，正丁基，仲丁基，叔丁基，直链或支链的基团，含有2至10个碳原子的饱和或单不饱和或不饱和脂族碳链，苯基和苯基乙酰基，其中R2和R3彼此独立地表示选自Cl，I，甲基，苯基或苯乙炔。

26. 发明申请

US20130030757A1 METHOD FOR RECONSTRUCTING THE INTERNAL STRUCTURE OF A SAMPLE BODY BY MEANS OF REFLECTION AND SCATTERING SIGNALS 审中-公开
标题翻译：通过反射和散射信号重建样品体内部结构的方法
公开(公告)号：US20130030757A1
公开(公告)日：2013-01-31
申请号：US13639767
申请日：2011-04-07
申请人： Rainer Stotzka , Nicole Ruiter
发明人： Rainer Stotzka , Nicole Ruiter
IPC分类号： G01B15/00 , G06F15/00
CPC分类号： G01S15/8977 , G06F17/11 , G06T11/006 , G06T2211/424 , G06T2211/436
摘要： One aspect of the invention relates to a method for reconstructing the spatial distribution of a reflection coefficient for waves in a sample body, comprising the following steps: parameterizing the sample body by means of N volume elements; determining M different measurement configurations of an emitting device and an associated receiving device; defining the number T of measurement points; setting up M path matrices G[i], wherein the possible paths of reflected or scattered waves are encoded in the i-th path matrix; registering M series of measurements, wherein an excitation signal a[i] is fed to the emitting device in the i-th series of measurements, and the associated receiving device (5) registers a series of measurements x[i]; calculating a predictive differential vector Δx=x−G·s[n], which contains the difference between the elements of the M registered series of measurements x[i]t and the predictable series of measurements G[i]tj·s[n]j; minimizing a norm of the predictive differential vector ∥Δx∥; and providing the reflection coefficients s[n]. The invention also relates to an apparatus for carrying out the method.
摘要翻译：本发明的一个方面涉及一种用于重建样本体中的波的反射系数的空间分布的方法，包括以下步骤：通过N个体积元素参数化样本体; 确定发射装置和相关联的接收装置的M个不同的测量配置; 定义测量点数T; 设置M路径矩阵G [i]，其中反射或散射波的可能路径被编码在第i路径矩阵中; 注册M系列测量，其中激励信号a [i]在第i系列测量中被馈送到发射设备，并且相关联的接收设备（5）记录一系列测量值x [i]; 计算预测差分矢量＆Dgr; x = x-G·s [n]，其包含M个记录的测量系列x [i] t的元素与可预测的测量系列G [i] tj·s之间的差 [n] j 最小化预测差分矢量∥＆Dgr; x |的范数; 并提供反射系数s [n]。本发明还涉及一种用于执行该方法的装置。

27. 发明申请

US20100305026A1 CD44V6 peptides as inhibitors of bacterial infections 审中-公开
标题翻译： CD44V6肽作为细菌感染的抑制剂
公开(公告)号：US20100305026A1
公开(公告)日：2010-12-02
申请号：US12658949
申请日：2010-02-16
申请人： Christian Jung , Véronique Orian-Rousseau , Alexandra Matzke , Helmut Ponta
发明人： Christian Jung , Véronique Orian-Rousseau , Alexandra Matzke , Helmut Ponta
IPC分类号： A61K38/08 , A61K38/10 , A61K38/12 , C07K7/06 , C07K7/64 , C07K7/08 , A61P31/04
CPC分类号： A61K38/178 , A61K38/12 , C07K14/70585 , Y02A50/411 , Y02A50/475
摘要： The present invention relates to the use of peptide compounds for the prevention and/or treatment of a bacterial infection.
摘要翻译：本发明涉及肽化合物用于预防和/或治疗细菌感染的用途。

28. 发明申请

US20210179424A1 METHOD FOR PRODUCING A MOULDED BODY 有权
公开(公告)号：US20210179424A1
公开(公告)日：2021-06-17
申请号：US17250087
申请日：2019-05-24
申请人： Karlsruher Institut fur Technologie
发明人： Norbert Schneider , Christian Koos , Matthias Worgull , Philipp-Immanuel Dietrich
IPC分类号： B81C99/00 , B29C59/02 , B29C59/00
摘要： The present invention relates to a method for producing a molded body (10), comprising the following steps: a) providing a molding tool (40) which has at least one receptacle (12) in which at least one material (30) which comprises at least one shape-memory material (31) is introduced, wherein the shape-memory material (31) is present in a first state (111), wherein the material (30) at least partially fills the receptacle (12) of the molding tool (40) in such a manner that said material adjoins at least one surface of the receptacle (12); b) creating a molded body (10) in the receptacle (12) of the molding tool (40) from the material (30), wherein the shape-memory material (31) is present in a second state (112), wherein a form (11) is embossed into the molded body (10) during the second state (112); c) transferring the shape-memory material (31) to a third state (113), wherein the molded body (10) can be deformed during the third state (113) in such a manner that the molded body (10) is demolded from the receptacle (12) of the molding tool (40); and d) at least partially restoring the form (11) of the molded body (10) by transferring the shape-memory material (31) to a fourth state (114), wherein the molded body (10) at least partially resumes the form (11) according to step b) during the fourth state (114).

29. 发明授权

US10551168B2 Deformation device, including an optical waveguide and method for measuring deformation of a tubular structure at multiple measuring points 有权
公开(公告)号：US10551168B2
公开(公告)日：2020-02-04
申请号：US15736923
申请日：2016-06-15
申请人： Karlsruher Institut für Technologie
发明人： Hendrikje Pauer , Christoph Ledermann
IPC分类号： G01B11/16 , G01D5/353
摘要： The invention includes an apparatus (110) and method (152) for determining a deformation (170) of a three-dimensional, flexible structure in the form of a tubular construct (112) with a minimum of optical waveguides. An optical waveguide (116) is introduced into the tubular construct (112), where the optical waveguide (116) extends as a helical winding (118) within the tubular construct (116) and has a multiplicity of strain measuring means (126). The configuration of the apparatus and method performed reduces the average material load of the strain measuring means and improves resolution and measurement range of the sensor (optical waveguide) while maintaining readout frequency of the strain measurements. The apparatus (110) also includes an evaluation device (130) configured to determine the deformation of the tubular construct (112), in particular in relation to an axis, surface and/or volume of the tubular construct (112), from measurement values (154) from the multiplicity of strain measuring means (126).

30. 发明申请

US20200003671A1 METHOD AND APPARATUS FOR DETERMINING A CONCENTRATION OF AEROSOL PARTICLES IN A CARRIER GAS 审中-公开
公开(公告)号：US20200003671A1
公开(公告)日：2020-01-02
申请号：US16448229
申请日：2019-06-21
申请人： Karlsruher Institut fur Technologie
发明人： Ottmar Mohler , Benjamin Murray , Michael Adams
IPC分类号： G01N15/06 , H05B3/46 , F17C13/02
摘要： The invention relates to a method (200) and an apparatus (110) for determining a concentration of aerosol particles (112) in a carrier gas (114), in particular for examining atmospheric aerosols (118) or as aerosol particle detector in process gases or in clean air rooms. The method (200) here comprises the steps: a) provision of an aerosol (118) which has aerosol particles (112) in a carrier gas (114) comprising at least one condensable component; b) introduction of at least part of the aerosol (118) into a chamber (120) of a pressure-rated vessel (116), wherein the chamber (120) is delimited by at least one wall (128), wherein the at least one wall (128) adjoining the chamber (120) is set to a temperature which is above a saturation temperature of at least one condensable component; c) subsequent removal of part of the aerosol (118) from the chamber (120), as a result of which a decrease in pressure in the chamber (120) occurs, as a result of which the at least one condensable component condenses at least partly on the aerosol particles (112); and d) determination of a concentration of aerosol particles (112) in the carrier gas (114) during removal of the part of the aerosol (118) from the chamber (120). The invention can be suitable, in particular, for examining atmospheric aerosols, in particular aerosol particles, but can also be used as aerosol particle detector in process gases or in clean air rooms.

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