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21. 发明申请

US20050271740A1 Injectable calcium phosphate cements and the preparation and use thereof 有权
公开(公告)号：US20050271740A1
公开(公告)日：2005-12-08
申请号：US11129029
申请日：2005-05-13
申请人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： A61C5/00 , A61C5/06 , A61K6/033 , A61K33/42 , A61L24/00 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B14/36 , C04B28/34
CPC分类号： A61L24/02 , A61C5/62 , A61K6/0008 , A61K6/0067 , A61K6/033 , A61K6/0643 , A61K33/42 , A61L24/001 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B14/366 , C04B28/34 , C04B28/344 , C04B28/346 , C04B2111/00836 , Y10T428/2991 , Y10T428/2993 , C04B20/008 , C04B40/0272 , C04B40/0218 , C04B40/0263 , C04B20/1014 , C04B22/064 , C04B22/126 , C04B20/023 , C04B20/107 , A61K6/087 , C08L89/00
摘要： A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm.

22. 发明授权

US06960249B2 Tetracalcium phosphate (TTCP) having calcium phosphate whisker on surface 有权
标题翻译：表面具有磷酸钙晶须的磷酸四钙（TTCP）
公开(公告)号：US06960249B2
公开(公告)日：2005-11-01
申请号：US10607023
申请日：2003-06-27
申请人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen , Kuan-Liang Lin , I-Chang Wang
发明人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen , Kuan-Liang Lin , I-Chang Wang
IPC分类号： A61C5/00 , A61K33/42 , A61L24/00 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B28/34 , C04B35/00 , C30B7/00 , C30B29/14 , C30B29/62
CPC分类号： A61L24/001 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B28/344 , C04B28/346 , C04B2111/00086 , C04B2111/00206 , C04B2111/0025 , C04B2111/00836 , C30B7/00 , C30B29/14 , C30B29/62 , Y10T428/2991 , Y10T428/2993 , C04B22/126 , C04B22/064 , C04B20/008 , C04B40/0082 , C04B40/0259 , C04B14/383
摘要： A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers or fine crystals on a surface thereof; the basic calcium phosphate whiskers or fine crystals having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm.
摘要翻译：公开了一种用于制备快速凝固的生物可再吸收的磷酸钙水泥的四磷酸钙（TTCP）颗粒。 TTCP颗粒在其表面上具有碱性磷酸钙晶须或细晶体; 碱性磷酸钙晶须或Ca / P摩尔比大于1.33的细晶体，其长度可达5000nm左右，宽度可达500nm左右。

23. 发明授权

US08329464B2 Implant surface treatment method having tissues integrated 有权
标题翻译：植入物表面处理方法具有组织结合
公开(公告)号：US08329464B2
公开(公告)日：2012-12-11
申请号：US12873536
申请日：2010-09-01
申请人： Wen-Cheng Chen , Chun-Cheng Hung , Chia-Ling Ko
发明人： Wen-Cheng Chen , Chun-Cheng Hung , Chia-Ling Ko
IPC分类号： C12N5/00 , C12N5/07 , C12N5/071 , C22C1/00 , C23C8/36 , C21D1/54 , C21D1/70 , B32B15/01 , A61C8/00
CPC分类号： A61L27/06 , A61L27/3813 , A61L27/3821 , A61L27/50 , A61L2400/18
摘要： The present disclosure uses different kinds of surface treatment processes on titanium-made dental implants. The growth and attachment conditions of bone cells (MC3T3-E), fibroblasts (NIH 3T3) and epidermal cells (XB-2) on the metal surface of titanium slices with different surface treatments are observed. Tetra-calcium phosphate is used to perform secondary sand-blasting process to clean up the metal surface and provide calcium ions for osteoblastoma physiology. Thus, by adjusting the cells adhesive and proliferative abilities, the success rate of the clinical applications in dental implant is improved.
摘要翻译：本公开在钛制牙科植入物上使用不同种类的表面处理方法。观察到不同表面处理的钛片的金属表面上的骨细胞（MC3T3-E），成纤维细胞（NIH 3T3）和表皮细胞（XB-2）的生长和附着条件。四磷酸钙用于进行二次喷砂处理以清理金属表面，并提供钙离子用于成骨细胞瘤生理学。因此，通过调整细胞粘附和增殖能力，提高了牙种植体临床应用的成功率。

24. 发明申请

US20110318835A1 Implant Surface Treatment Method Having Tissues Integrated 有权
标题翻译：具有组织的植入物表面处理方法
公开(公告)号：US20110318835A1
公开(公告)日：2011-12-29
申请号：US12873536
申请日：2010-09-01
申请人： Wen-Cheng Chen , Chun-Cheng Hung , Chia-Ling Ko
发明人： Wen-Cheng Chen , Chun-Cheng Hung , Chia-Ling Ko
IPC分类号： C12N5/077
CPC分类号： A61L27/06 , A61L27/3813 , A61L27/3821 , A61L27/50 , A61L2400/18
摘要： The present disclosure uses different kinds of surface treatment processes on titanium-made dental implants. The growth and attachment conditions of bone cells (MC3T3-E), fibroblasts(NIH 3T3) and epidermal cells (XB-2) on the metal surface of titanium slices with different surface treatments are observed. Tetra-calcium phosphate is used to perform secondary sand-blasting process to clean up the metal surface and provide calcium ions for osteoblastoma physiology. Thus, by adjusting the cells adhesive and proliferative abilities, the success rate of the clinical applications in dental implant is improved.
摘要翻译：本公开在钛制牙科植入物上使用不同种类的表面处理方法。观察到不同表面处理的钛片的金属表面上的骨细胞（MC3T3-E），成纤维细胞（NIH 3T3）和表皮细胞（XB-2）的生长和附着条件。四磷酸钙用于进行二次喷砂处理以清理金属表面，并提供钙离子用于成骨细胞瘤生理学。因此，通过调整细胞粘附和增殖能力，提高了牙种植体临床应用的成功率。

25. 发明授权

US07258734B2 Injectable calcium phosphate cements and the preparation and use thereof 失效
标题翻译：可注射的磷酸钙水泥及其制备和应用
公开(公告)号：US07258734B2
公开(公告)日：2007-08-21
申请号：US11129227
申请日：2005-05-13
申请人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： C04B28/34
CPC分类号： A61L24/02 , A61C5/62 , A61K6/0008 , A61K6/0067 , A61K6/033 , A61K6/0643 , A61K33/42 , A61L24/001 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B14/366 , C04B28/34 , C04B28/344 , C04B28/346 , C04B2111/00836 , Y10T428/2991 , Y10T428/2993 , C04B20/008 , C04B40/0272 , C04B40/0218 , C04B40/0263 , C04B20/1014 , C04B22/064 , C04B22/126 , C04B20/023 , C04B20/107 , A61K6/087 , C08L89/00
摘要： A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm.
摘要翻译：公开了一种适用于牙齿和骨假体的磷酸钙骨水泥，其包括直径为0.05至100微米的磷酸钙颗粒，其中表面上的所述磷酸钙颗粒具有宽度范围为1至100的晶须或细晶体 nm，长度范围为1〜1000nm。

26. 发明授权

US07214265B2 Injectable calcium phosphate cements and the preparation and use thereof 失效
公开(公告)号：US07214265B2
公开(公告)日：2007-05-08
申请号：US11129063
申请日：2005-05-13
申请人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： C04B28/34
CPC分类号： A61L24/02 , A61C5/62 , A61K6/0008 , A61K6/0067 , A61K6/033 , A61K6/0643 , A61K33/42 , A61L24/001 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B14/366 , C04B28/34 , C04B28/344 , C04B28/346 , C04B2111/00836 , Y10T428/2991 , Y10T428/2993 , C04B20/008 , C04B40/0272 , C04B40/0218 , C04B40/0263 , C04B20/1014 , C04B22/064 , C04B22/126 , C04B20/023 , C04B20/107 , A61K6/087 , C08L89/00
摘要： A calcium phosphate cement suitable for use in dental and bone prosthesis is disclosed, which include calcium phosphate particles having a diameter of 0.05 to 100 microns, wherein said calcium phosphate particles on their surfaces have whiskers or fine crystals having a width ranging from 1 to 100 nm and a length ranging from 1 to 1000 nm.

27. 发明授权

US07204876B2 Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same 失效
公开(公告)号：US07204876B2
公开(公告)日：2007-04-17
申请号：US11133165
申请日：2005-05-19
申请人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Chern Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： C04B12/02
CPC分类号： A61K6/0643 , A61K6/033 , A61L24/001 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B28/344 , C04B28/346 , C04B2111/00086 , C04B2111/00206 , C04B2111/00836 , Y10T428/2991 , Y10T428/2993 , C04B20/008 , C04B22/064 , C04B40/0082 , C04B40/0259 , C04B14/383
摘要： A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase.

28. 发明申请

US20060115190A1 Bearing structure 审中-公开
标题翻译：轴承结构
公开(公告)号：US20060115190A1
公开(公告)日：2006-06-01
申请号：US11260148
申请日：2005-10-28
申请人： Wen-Cheng Chen , Jin-Juh Hsu
发明人： Wen-Cheng Chen , Jin-Juh Hsu
IPC分类号： F16C32/06
CPC分类号： F16C33/107 , F16C17/026 , F16C33/103
摘要： A bearing structure. A bearing is disposed in a bushing and includes a through hole and a slot. The slot receives a lubricant. An inner wall forming the through hole includes at lease one spiral-shaped furrows for guiding the lubricant into the slot. The inner wall of the bearing is divided into a first section and a second section by the slot. The spiral-shaped furrows on the first section and on the second section have different spiral directions for separately guiding the lubricant into the slot. The lubricant received in the slot can be lubricating oil. The bearing structure prevents leakage of the lubricant and effectively retains the lubricant in the bearing.
摘要翻译：轴承结构。轴承设置在衬套中并且包括通孔和槽。槽接收润滑剂。形成通孔的内壁至少包括一个用于将润滑剂引导到槽中的螺旋形沟槽。轴承的内壁由狭槽分为第一部分和第二部分。第一部分和第二部分上的螺旋形沟槽具有不同的螺旋方向，用于将润滑剂分开引导到槽中。容纳在槽中的润滑油可以是润滑油。轴承结构防止润滑剂泄漏并有效地将润滑剂保留在轴承中。

29. 发明申请

US20050279252A1 Tetracalcium phosphate (TTCP) with surface whiskers and method of making same 失效
标题翻译：具有表面晶须的磷酸四钙（TTCP）及其制备方法
公开(公告)号：US20050279252A1
公开(公告)日：2005-12-22
申请号：US11131892
申请日：2005-05-18
申请人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： A61C5/00 , A61K33/42 , A61L24/00 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B28/34 , C04B35/00 , C30B7/00 , C30B29/14 , C30B29/62
CPC分类号： A61L24/001 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B28/344 , C04B28/346 , C04B2111/00086 , C04B2111/00206 , C04B2111/0025 , C04B2111/00836 , C30B7/00 , C30B29/14 , C30B29/62 , Y10T428/2991 , Y10T428/2993 , C04B22/126 , C04B22/064 , C04B20/008 , C04B40/0082 , C04B40/0259 , C04B14/383
摘要： A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers or fine crystals on a surface thereof; the basic calcium phosphate whiskers or fine crystals having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm.
摘要翻译：公开了一种用于制备快速凝固的生物可再吸收的磷酸钙水泥的四磷酸钙（TTCP）颗粒。 TTCP颗粒在其表面上具有碱性磷酸钙晶须或细晶体; 碱性磷酸钙晶须或Ca / P摩尔比大于1.33的细晶体，其长度可达5000nm左右，宽度可达500nm左右。

30. 发明申请

US20050274287A1 Calcium phosphate cements made from (TTCP) with surface whiskers and process for preparing same 失效
公开(公告)号：US20050274287A1
公开(公告)日：2005-12-15
申请号：US11133166
申请日：2005-05-19
申请人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
发明人： Jiin-Huey Lin , Chien-Ping Ju , Wen-Cheng Chen
IPC分类号： A61L24/00 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B28/34 , C04B35/00
CPC分类号： A61K6/0643 , A61K6/033 , A61L24/001 , A61L24/02 , A61L27/12 , A61L27/50 , C04B12/02 , C04B12/025 , C04B28/344 , C04B28/346 , C04B2111/00086 , C04B2111/00206 , C04B2111/00836 , Y10T428/2991 , Y10T428/2993 , C04B20/008 , C04B22/064 , C04B40/0082 , C04B40/0259 , C04B14/383
摘要： A tetracalcium phosphate (TTCP) particle for use in preparing a fast-setting, bioresorbable calcium phosphate cement is disclosed. The TTCP particle has a basic calcium phosphate whiskers on a surface thereof; the basic calcium phosphate whiskers having a Ca/P molar ratio greater than 1.33, and having a length up to about 5000 nm and a width up to about 500 nm. The basic calcium phosphate whiskers are substantially free of a hydroxyapatite phase and mainly composed of TTCP phase.

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