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21. 发明授权

US09574001B2 Humanized single-chain antibody against beta 3 integrin for the treatment and prevention of metastasis 有权
标题翻译：针对β3整联蛋白的人源化单链抗体用于治疗和预防转移
公开(公告)号：US09574001B2
公开(公告)日：2017-02-21
申请号：US13958145
申请日：2013-08-02
申请人： Thomas M. Wisniewski , Wei Zhang , Suying Dang
发明人： Thomas M. Wisniewski , Wei Zhang , Suying Dang
IPC分类号： A61K39/395 , C07K16/28 , A61K39/00
CPC分类号： C07K16/2848 , A61K2039/505 , C07K2317/622 , C07K2317/73
摘要： The present invention relates to methods inhibiting tumor metastasis and treating cancer in a subject that involve administering to the subject an antibody which recognizes GPIIIa49-66, under conditions effective to inhibit tumor metastasis and/or treat cancer in the subject.
摘要翻译：本发明涉及在受试者中抑制肿瘤转移和治疗癌症的方法，所述方法包括在有效抑制肿瘤转移和/或治疗受试者的癌症的条件下向受试者施用识别GPIIIa49-66的抗体。

22. 发明授权

US09478746B2 Electron donor-fullerene conjugated molecules for organic photovoltaic cells 有权
标题翻译：用于有机光伏电池的电子供体 - 富勒烯共轭分子
公开(公告)号：US09478746B2
公开(公告)日：2016-10-25
申请号：US13911351
申请日：2013-06-06
申请人： Xiong Gong , Stephen Z. D. Cheng , Wei Zhang
发明人： Xiong Gong , Stephen Z. D. Cheng , Wei Zhang
IPC分类号： H01L51/00 , H01L51/42
CPC分类号： H01L51/0047 , H01L51/0037 , H01L51/0043 , H01L51/0077 , H01L51/4253 , H01L2251/308 , Y02E10/549
摘要： A photovoltaic cell has an active area formed electron donor-fullerene conjugated molecules. The electron donor is formed of a polymer, which is conjugated with an electron acceptor, such as fullerene. By conjugating the fullerene, such as C60, with electron donor moieties, such as that of the polymer, double channels are formed therebetween, whereby one channel provides hole transport and the other channel provides electron transport. As a result, the electronic coupling between the fullerene and the electron donor moiety leads to increased short-circuit current density (Jsc) and increased open-circuit voltage (Voc), resulting in high power conversion efficacy (PCE) in the solar cell.
摘要翻译：光伏电池具有形成的电子供体 - 富勒烯共轭分子的有源区。电子给体由与电子受体（例如富勒烯）共轭的聚合物形成。通过将诸如C60的富勒烯与诸如聚合物的电子供体部分共轭，在其间形成双通道，由此一个通道提供空穴传输，另一个通道提供电子传输。结果，富勒烯和电子给体部分之间的电子耦合导致短路电流密度（Jsc）增加和开路电压（Voc）增加，导致太阳能电池中的高功率转换效率（PCE）。

23. 发明授权

US09453062B2 Glucose dependent insulinotropic polypeptide analogs, pharmaceutical compositions and use thereof 有权
标题翻译：葡萄糖依赖性促胰岛素多肽类似物，药物组合物及其用途
公开(公告)号：US09453062B2
公开(公告)日：2016-09-27
申请号：US14125061
申请日：2012-06-08
申请人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
发明人： Tao Ma , Shusen Xu , Zhijun Liu , Bo Zhang , Ning Shen , Hai Yang , Wei Zhang , Yuhua Li , Sunghwan Moon , Maengsup Kim
IPC分类号： A61K38/22 , A61K38/00 , A61K38/28 , A61K38/26 , A61K38/16 , A61P3/04 , A61P3/10 , A61P7/12 , A61P19/10 , C07K14/605 , C07K5/00 , C07K7/00 , C07K16/00 , C07K17/00 , C07K14/575 , C07K14/00
CPC分类号： C07K14/575 , A61K38/00 , A61K38/16 , A61K38/22 , C07K14/00 , C07K14/605
摘要： The present invention provides a GIP analog, which is derived from GIP (1-29, SEQ ID NO: 1), has both GLP-1 agonist activity and GIPR stimulation activity, and comprises an amino acid sequence represented by the following formula I: Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp-Leu- A27-A28-A29-Y. The present invention also provides a pharmaceutical composition comprising the GIP analog and use thereof.
摘要翻译：本发明提供衍生自GIP（1-29，SEQ ID NO：1）的GIP类似物具有GLP-1激动剂活性和GIPR刺激活性，并且包含由下式I表示的氨基酸序列： Tyr-A2-A3-Gly-Thr-Phe-A7-Ser-Asp-Tyr-Ser-A12-A13-A14-A15-Lys-A17-A18-A19-A20-A21-A22-A23-A24-Trp- Leu- A27-A28-A29-Y。本发明还提供了包含GIP类似物及其用途的药物组合物。

24. 发明授权

US09266898B2 Reaction product from the co-dehydration of a sugar alcohol and a polyol 有权
标题翻译：来自糖醇和多元醇共脱水的反应产物
公开(公告)号：US09266898B2
公开(公告)日：2016-02-23
申请号：US13994499
申请日：2011-12-16
申请人： Timothy Walter Abraham , Donald Michael Ference , Wei Zhang
发明人： Timothy Walter Abraham , Donald Michael Ference , Wei Zhang
IPC分类号： C07D493/04 , C08G18/32 , C08G18/48 , C08G18/40 , C08G101/00
CPC分类号： C07D493/04 , C08G18/3218 , C08G18/4018 , C08G18/4883 , C08G2101/0025 , C08G2101/0083 , C08G2105/02
摘要： A reaction product of the co-dehydration of a sugar alcohol and a reactant polyol having a number average hydroxyl functionality less than 4.0 is disclosed. In some aspects the sugar alcohol comprises mannitol, sorbitol, xylitol, erythritol, or mixtures thereof. In some preferred aspects the sugar alcohol comprises sorbitol. In some aspects the reactant polyol has an average molecular weight of from 40 to 500 Daltons. In some aspects, the reaction product may be suitable for the manufacture of polyisocyanurate foam. In some aspects the reaction product may be mixed with diluent polyols, such as diols, glycols, ethylene glycol, diethylene glycol, dipropylene glycol, propylene glycol, polyethylene glycol, polypropylene glycol and mixtures thereof.
摘要翻译：公开了糖醇与数均羟基官能度小于4.0的反应物多元醇共脱水的反应产物。在一些方面，糖醇包括甘露醇，山梨糖醇，木糖醇，赤藓醇或其混合物。在一些优选方面，糖醇包含山梨糖醇。在一些方面，反应物多元醇的平均分子量为40至500道尔顿。在一些方面，反应产物可适用于制备聚异氰脲酸酯泡沫。在一些方面，反应产物可与稀释剂多元醇，例如二醇，二醇，乙二醇，二甘醇，二丙二醇，丙二醇，聚乙二醇，聚丙二醇及其混合物混合。

25. 发明授权

US09181419B2 Toughened plastics and its preparation method 有权
标题翻译：增韧塑料及其制备方法
公开(公告)号：US09181419B2
公开(公告)日：2015-11-10
申请号：US10415769
申请日：2001-11-05
申请人： Jinliang Qiao , Yigun Liu , Shijun Zhang , Xiaohong Zhang , Jianming Gao , Wei Zhang , Genshuan Wei , Jingbo Shao , Hua Yin , Renli Zhai , Zhihai Song , Fan Huang
发明人： Jinliang Qiao , Yigun Liu , Shijun Zhang , Xiaohong Zhang , Jianming Gao , Wei Zhang , Genshuan Wei , Jingbo Shao , Hua Yin , Renli Zhai , Zhihai Song , Fan Huang
IPC分类号： C08L23/12 , C08L23/16 , C08L25/04 , C08L21/00 , C08L25/06 , C08L25/10 , C08L25/12
CPC分类号： C08L21/00 , C08L23/12 , C08L23/16 , C08L25/06 , C08L25/10 , C08L25/12 , C08L2205/03 , C08L2207/02
摘要： A toughened plastic and its preparation method, with the toughened plastic being obtained by rubber-plastic blending of brittle or less brittle plastics and a rubber mixture. The rubber mixture consists of powdery rubbers having a cross-linked structure and an average particle size of not more than 0.50 μm, and at least one selected from the group consisting of unvulcanized rubbers and thermoplastic elastomers. The morphology and the particle size distribution of the rubber phase contained in the toughened plastic can be controlled by changing the particle size of the powdery rubbers having a cross-linking structure and choosing proper unvulcanized rubbers or thermoplastic elastomers. The toughened plastic has good toughness and processability while keeping better strength and stiffness.
摘要翻译：增韧塑料及其制备方法，通过橡胶 - 塑料混合脆性或较不脆的塑料和橡胶混合物获得增韧塑料。橡胶混合物由具有交联结构且平均粒度不大于0.50μm的粉末状橡胶和选自未硫化橡胶和热塑性弹性体的至少一种组成。可以通过改变具有交联结构的粉末橡胶的粒度并选择合适的未硫化橡胶或热塑性弹性体来控制增韧塑料中包含的橡胶相的形态和粒度分布。增韧的塑料具有良好的韧性和加工性能，同时保持更好的强度和刚度。

26. 发明授权

US09158014B2 Acoustic source apparatus, systems, and methods 有权
标题翻译：声源设备，系统和方法
公开(公告)号：US09158014B2
公开(公告)日：2015-10-13
申请号：US14386671
申请日：2012-04-09
申请人： Clovis Bonavides , Batakrishna Mandal , Arthur Cheng , Wei Zhang , Philip William Tracadas , Gary Kainer , Hong Li Hou , Burkay Donderici
发明人： Clovis Bonavides , Batakrishna Mandal , Arthur Cheng , Wei Zhang , Philip William Tracadas , Gary Kainer , Hong Li Hou , Burkay Donderici
IPC分类号： G01V1/40 , G01V1/143
CPC分类号： G01V1/143 , G01V2210/1299
摘要： In some embodiments, an apparatus and a system, as well as a method and an article, may operate to rotate a rotatable driving member having at least one driving lobe, and to periodically contact at least one cam on a unitary driven member with the at least one driving lobe during rotation of the rotatable driving member, to set the driven member in motion. This motion can be used to launch an acoustic wave along an axis substantially orthogonal to the axis of rotation of the driving member, where the driving member disposed completely within the driven member. The signature of the acoustic wave can be at least partially determined by the profile of the cam and the rotation rate of the driving member. Additional apparatus, systems, and methods are disclosed.
摘要翻译：在一些实施例中，装置和系统以及方法和制品可以操作以旋转具有至少一个驱动凸角的可旋转驱动构件，并且周期性地接触单一从动构件上的至少一个凸轮，在可旋转驱动构件的旋转期间至少一个驱动凸轮，以使从动构件运动。该运动可以用于沿着基本上垂直于驱动构件的旋转轴线的轴线发射声波，其中驱动构件完全设置在从动构件内。声波的签名可以至少部分地由凸轮的轮廓和驱动构件的旋转速度决定。公开了附加装置，系统和方法。

27. 发明授权

US09116176B2 Optical current transformer for gas-insulated apparatus 有权
标题翻译：气体绝缘设备用光电流互感器
公开(公告)号：US09116176B2
公开(公告)日：2015-08-25
申请号：US13697100
申请日：2011-05-12
申请人： Wei Zhang , Masashi Kawamata , Hiroyuki Nakamichi , Tatsushi Yamaguchi , Daigorou Shiozawa
发明人： Wei Zhang , Masashi Kawamata , Hiroyuki Nakamichi , Tatsushi Yamaguchi , Daigorou Shiozawa
IPC分类号： G01R31/00 , G01R19/00 , G01R15/24 , H02B13/035
CPC分类号： G01R19/00 , G01R15/246 , H02B13/0356
摘要： At least one conductor is disposed in sealed vessel, which is filled with insulating gas, an hand hole is provided to a part of sealed vessel and is closed by a sealed cover, and optical fibers are disposed that form a closed loop surrounding conductor in sealed vessel. Optical fibers are hermetically led out of sealed vessel from sealed cover and are provided with at least a light source unit and an optical signal processor unit at the lead-out end. An airtight hollow tube disposed looping around leaving a predefined distance of separation is provided to conductor in sealed vessel, the end of tube is hermetically connected to sealed cover by sealing/bonding means, and optical fibers can be inserted in sealing/bonding means.
摘要翻译：至少一根导体设置在密封容器中，其中填充有绝缘气体，手动孔设置在密封容器的一部分，并由密封盖封闭，并且光纤布置成围绕导体封闭的环形密封船只。光纤从密封的盖子密封地引出密封的容器，并且在引出端设置有至少一个光源单元和光信号处理器单元。在密封容器中的导体上设置环绕环形留置预定距离的气密中空管，管的端部通过密封/粘合装置气密地连接到密封盖上，并且光纤可插入密封/粘合装置中。

28. 发明申请

US20150132883A1 PHOTO DETECTOR CONSISTING OF TUNNELING FIELD-EFFECT TRANSISTORS AND THE MANUFACTURING METHOD THEREOF 审中-公开
标题翻译：隧道场效应晶体管的照相检测器及其制造方法
公开(公告)号：US20150132883A1
公开(公告)日：2015-05-14
申请号：US14600196
申请日：2015-01-20
申请人： Pengfei Wang , Xi Lin , Wei Wang , Xiaoyong Liu , Wei Zhang
发明人： Pengfei Wang , Xi Lin , Wei Wang , Xiaoyong Liu , Wei Zhang
IPC分类号： H01L31/18 , H01L31/113 , H01L31/0232
CPC分类号： H01L31/1804 , G02B6/42 , G02B6/4214 , H01L27/2454 , H01L27/304 , H01L31/02327 , H01L31/113 , H01L31/1136 , Y02E10/547 , Y02P70/521
摘要： The present invention belongs to the technical field of optical interconnection and relates to a photo detector, in particular to a photo detector consisting of tunneling field-effect transistors.
摘要翻译：本发明属于光互连的技术领域，涉及光检测器，特别涉及由隧道场效应晶体管构成的光检测器。

29. 发明授权

US08898169B2 Automated product attribute selection 有权
标题翻译：自动产品属性选择
公开(公告)号：US08898169B2
公开(公告)日：2014-11-25
申请号：US13292852
申请日：2011-11-09
申请人： Salih B. Gokturk , Wei Zhang , Emilio Rodriguez Antunez, III , Baris Sumengen
发明人： Salih B. Gokturk , Wei Zhang , Emilio Rodriguez Antunez, III , Baris Sumengen
IPC分类号： G06F17/30 , G06Q30/02
CPC分类号： G06F17/30873 , G06Q30/0278
摘要： Product data for a product is received by an attribute selection module. The product data includes product image data and product text data. This product data is used to generate a plurality of probability distributions for a category. The category includes a plurality of attributes, and the probability distribution includes a plurality of probabilities indicating the likelihoods that attributes of the category are applicable to the product. The plurality of probability distributions for the category are weighted and summed to generate a combined probability distribution for the category. An attribute label is determined by selecting an attribute from the category that is indicated to be most likely applicable to the product based on the combined probability distribution for the category. The attribute label is associated with the product. The attribute label enables other services to search for and retrieve the product based on the attribute.
摘要翻译：产品的产品数据由属性选择模块接收。产品数据包括产品图像数据和产品文本数据。该产品数据用于为类别生成多个概率分布。该类别包括多个属性，并且概率分布包括指示类别的属性适用于产品的可能性的多个概率。对类别的多个概率分布进行加权和求和，以生成该类别的组合概率分布。通过根据该类别的组合概率分布来选择指示为最可能适用于该产品的类别的属性来确定属性标签。属性标签与产品相关联。属性标签使其他服务可以根据属性搜索和检索产品。

30. 发明授权

US08883880B2 Soluble shell polymer composition and method for its preparation 有权
标题翻译：可溶性壳聚合物组合物及其制备方法
公开(公告)号：US08883880B2
公开(公告)日：2014-11-11
申请号：US13597335
申请日：2012-08-29
申请人： Monica Luckenbach , Ozzie M. Pressley , Wei Zhang
发明人： Monica Luckenbach , Ozzie M. Pressley , Wei Zhang
IPC分类号： C08F265/06 , C08K5/42 , C08F230/02 , C09D151/06 , C09D151/00 , C08L51/00
CPC分类号： C08F265/06 , C08F230/02 , C09D151/06 , C08F2/22
摘要： The present invention relates to a soluble shell polymer composition comprising an alkali soluble emulsion polymer shell and an alkali insoluble emulsion polymer core, which composition is stabilized by a surfactant of the formula R—(OCH2CH2)2-6OSO3−M+, where R is a linear, branched, or cyclic C8-C24 alkyl or C12-C18 aralkyl group and M+ is a counterion. The invention further relates to a method of preparing the composition and its use as a binder in coatings formulations. Formulations prepared with the soluble shell polymer composition have excellent freeze-thaw profiles and hiding.
摘要翻译：本发明涉及一种可溶性壳聚合物组合物，其包含碱溶性乳液聚合物壳和碱不溶性乳液聚合物核心，该组合物由式R-（OCH 2 CH 2）2 -POSO 3 -M +的表面活性剂稳定，其中R为直链，支链或环状C 8 -C 24烷基或C 12 -C 18芳烷基，M +为抗衡离子。本发明还涉及一种制备组合物的方法及其在涂料制剂中作为粘合剂的用途。用可溶性壳聚合物组合物制备的制剂具有优异的冻融特性和隐藏性。

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