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21. 发明授权

US09463282B2 Arrangement for coupling a plunger to either a syringe or a stopper 有权
标题翻译：用于将柱塞连接到注射器或塞子的布置
公开(公告)号：US09463282B2
公开(公告)日：2016-10-11
申请号：US13876786
申请日：2011-10-06
申请人： Timothy Donald Barrow-Williams , Yannick Hourmand , Matthew Ekman
发明人： Timothy Donald Barrow-Williams , Yannick Hourmand , Matthew Ekman
IPC分类号： A61M5/315 , A61M5/20 , A61M5/31 , A61M5/32
CPC分类号： A61M5/31513 , A61M5/2033 , A61M5/3129 , A61M5/31511 , A61M5/3204 , A61M5/3232 , A61M2005/206 , A61M2005/2073 , A61M2005/3107
摘要： An arrangement for coupling a plunger to either a syringe or a stopper arranged in the syringe. The arrangement includes a syringe holder which is slidably arranged in a housing. The syringe holder is provided with at least one resilient syringe holder arm arranged distally, the syringe holder arm having an inclined surface for bearing against a shoulder, which is arranged at the plunger. The syringe holder arm is supportable by an inner surface of the housing in order to prevent it from being flexed outward in a first position. A widened portion is provided in the housing for allowing the syringe holder arm to flex outwards and disconnect from the plunger when in a more proximal position so as to switch load of the plunger from the syringe to the stopper.
摘要翻译：用于将柱塞联接到设置在注射器中的注射器或塞子的装置。该装置包括可滑动地布置在壳体中的注射器保持器。注射器保持器设置有至少一个向远侧布置的弹性注射器保持臂，注射器保持臂具有用于抵靠肩部的倾斜表面，肩部设置在柱塞处。注射器支架臂可由壳体的内表面支撑，以防止其在第一位置向外弯曲。在外壳中设置加宽部分，用于允许注射器保持器臂在更接近的位置向外向外弯曲并与柱塞断开，从而将柱塞从注射器的负载切换到止动件。

22. 发明授权

US09352088B2 Auto-injector 有权
标题翻译：自动进样器
公开(公告)号：US09352088B2
公开(公告)日：2016-05-31
申请号：US13806324
申请日：2011-06-27
申请人： Matthew Ekman , Yannick Hourmand , Timothy Donald Barrow-Williams
发明人： Matthew Ekman , Yannick Hourmand , Timothy Donald Barrow-Williams
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/2033 , A61M5/3202 , A61M5/3257 , A61M2005/206 , A61M2005/208
摘要： Auto-injector for administering a dose of a liquid medicament includes a housing to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the housing having a distal end (D) and a proximal end (P) with an orifice to apply against an injection site. A spring means, upon activation, can push the needle from inside the housing through the orifice and past the proximal end (P), operate the syringe to supply the dose of medicament (M), and retract the syringe with the needle after delivering the medicament (M). An activating means can lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection.
摘要翻译：用于施用一定剂量的液体药物的自动注射器包括容纳具有中空针的注射器的壳体和用于密封注射器并使药剂（M）移位的止动件，壳体具有远端（D）和近端（P）具有孔口以施加在注射部位上。弹簧装置在启动时可以将针从壳体内部通过孔并推过近端（P），操作注射器以提供剂量的药物（M），并且在递送药物（M）。激活装置可以在手动操作之前将弹簧装置锁定在加压状态，并且能够在手动操作时释放用于注射的弹簧装置。

23. 发明申请

US20140135705A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20140135705A1
公开(公告)日：2014-05-15
申请号：US13964435
申请日：2013-08-12
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20
CPC分类号： A61M5/3257 , A61M5/20 , A61M5/2033 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing, a syringe with needle and a stopper, a drive spring for pushing the needle from a covered position into an advanced position, for operating the syringe and for retracting the syringe, activating means for locking or releasing the spring means. A retraction sleeve is axially movable arranged in the housing. The drive spring bears with its proximal end against a thrust face of a decoupling member. At least one resilient decoupling arm is arranged at the decoupling member for bearing against a first shoulder of the plunger. At least one aperture is arranged in the retraction sleeve allowing the decoupling arms to be flexed outward thus allowing the first shoulder to slip past the decoupling arm. The aperture is arranged to be angularly misaligned with respect to the decoupling arm and to rotate so as to align with the decoupling arms upon translation of the retraction sleeve out of the proximal position in distal direction.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，其包括：细长壳体，具有针头和止动器的注射器，用于将针从覆盖位置推入到前进位置的驱动弹簧，用于操作注射器并用于缩回注射器，用于锁定或释放弹簧装置的启动装置。缩回套筒可轴向移动地布置在壳体中。驱动弹簧的近端靠近解耦构件的推力面。至少一个弹性解耦臂布置在去耦构件上以抵靠柱塞的第一肩部。至少一个孔口设置在缩回套筒中，允许去耦臂向外弯曲，从而允许第一肩部滑过去耦臂。孔被布置成相对于去耦臂成角度地不对准，并且当远离方向平移缩回套筒离开近端位置时，旋转以便与解耦臂对齐。

24. 发明申请

US20130317448A1 Auto-Injector with Injection Damper 有权
标题翻译：带注射阻尼器的自动进样器
公开(公告)号：US20130317448A1
公开(公告)日：2013-11-28
申请号：US13806965
申请日：2011-06-20
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/48
CPC分类号： A61M5/484 , A61M5/20 , A61M5/2033 , A61M5/3158 , A61M5/321 , A61M5/3234 , A61M5/3243 , A61M5/326 , A61M5/46 , A61M5/482 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/31508 , A61M2005/3151 , A61M2005/3152
摘要： The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, the housing having a distal end and a proximal end with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. The spring means is a single drive spring arranged to be grounded at a distal end in the housing for advancing the needle and for injecting the dose of medicament via a plunger and wherein the drive spring is arranged to have its ground in the housing switched to its proximal end for retracting the syringe. A damper is arranged around the plunger, wherein the damper is arranged with the plunger by a spline so as to cause rotation of either the plunger or the damper at least during part of a translation of the plunger in proximal direction and share the load of the drive spring between the translation and the rotation.
摘要翻译：本发明涉及一种用于给药液体药物的自动注射器，包括：细长壳体，布置成容纳具有中空针头的注射器和用于密封注射器并使药剂移位的塞子，壳体具有远端和具有旨在施加在注射部位上的孔口的近端，其中所述注射器相对于所述壳体可滑动地布置;弹簧装置，其能够在启动时：将所述针从所述壳体内的覆盖位置推入到前进位置并且经过近端，操作注射器以提供剂量的药物，并且在输送药物之后将针头注射到被覆盖的位置，激活装置被布置成在手动操作之前将弹簧装置锁定在加压状态并且能够在手动操作时释放用于注射的弹簧装置。弹簧装置是单个驱动弹簧，其布置成在壳体中的远端处接地，用于推进针头并且用于经由柱塞喷射剂量的药剂，并且其中驱动弹簧被布置成使得其壳体中的地面切换到其近端用于缩回注射器。阻尼器布置在柱塞周围，其中阻尼器通过花键设置有柱塞，以便至少在柱塞在近端方向的平移过程的一部分期间引起柱塞或阻尼器的旋转，并共享负载驱动弹簧之间的平移和旋转。

25. 发明申请

US20130267909A1 AUTO-INJECTOR 有权
标题翻译：自动注射器
公开(公告)号：US20130267909A1
公开(公告)日：2013-10-10
申请号：US13993531
申请日：2011-12-21
申请人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Yannick Hourmand , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32
CPC分类号： A61M5/3245 , A61M5/2033 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： According to the invention, an auto-injector for administering a dose of a liquid medicament (M) comprises of a substantially cylindrical housing arranged to contain a pre-filled syringe; a syringe retainer slidably arranged with respect to the housing that mounts a pre-filled syringe with an injection needle, a plunger and a stopper for sealing a syringe barrel of the pre-filled syringe; a coupling shroud slidably arranged within the housing and releasably coupled to the plunger; and a single drive means. Upon release, the single drive means is capable of driving the coupling shroud in the proximal direction (P). The proximal translatory movement of the coupling shroud with respect to the housing, translates the syringe retainer in the proximal direction (P) to expose the injection needle of the pre-filled syringe, depresses the plunger connected to the stopper into the syringe barrel to expel the dose of medicament (M) and advances a needle shroud to a safe position (PS) to surround the injection needle after the medicament (M) has been at least partially delivered. The coupling shroud is decoupled from the plunger at a pre-determined second position (II) defined by an aperture formed into the housing.
摘要翻译：根据本发明，用于给药液体药物（M）的自动注射器包括布置成容纳预填充注射器的基本上圆柱形的壳体; 相对于所述壳体可滑动地布置的注射器保持器，其用注射针，柱塞和用于密封所述预先填充的注射器的注射器筒的止动器安装预填充的注射器; 联接罩，其可滑动地布置在所述壳体内并且可释放地联接到所述柱塞; 和单个驱动装置。在释放时，单个驱动装置能够沿近端方向（P）驱动联接罩。耦合护罩相对于壳体的近侧平移运动使注射器保持器沿近端方向（P）平移以暴露预填充注射器的注射针，将连接到塞子的柱塞压入注射器筒以排出药剂（M）的剂量并且在药物（M）已经被至少部分递送之后，将针罩延伸到安全位置（PS）以包围注射针。耦合罩在由形成在壳体中的孔限定的预定的第二位置（II）处与柱塞分离。

26. 发明申请

US20130150801A1 Auto-Injector 有权
标题翻译：自动进样器
公开(公告)号：US20130150801A1
公开(公告)日：2013-06-13
申请号：US13579435
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： A61M5/32
CPC分类号： A61M5/2033 , A61M5/3204 , A61M5/3232 , A61M5/326 , A61M2005/206 , A61M2005/2073
摘要： The invention relates to an auto-injector (1) for administering a dose of a liquid medicament (M), comprising: an elongate housing (2) arranged to contain a syringe (3) with a hollow needle (4) and a stopper (6) for sealing the syringe (3) and displacing the medicament (M), the housing (2) having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe (3) is slidably arranged with respect to the housing (2), spring means (8) capable of, upon activation: pushing the needle (4) from a covered position inside the housing (2) into an advanced position through the orifice and past the proximal end (P), operating the syringe (3) to supply the dose of medicament (M), and retracting the syringe (3) with the needle (4) into the covered position after delivering the medicament (M), activating means (20) arranged to lock the spring means (8) in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means (8) for injection. The spring means (8) is a single compression spring (8) arranged to be grounded at a distal end (8.1) in the housing (2) for advancing the needle (4) and for injecting the dose of medicament (M) via a plunger (9) and wherein the compression spring (8) is arranged to have its ground in the housing (2) switched to its proximal end (8.2) for retracting the syringe (3).
摘要翻译：本发明涉及一种用于施用剂量的液体药物（M）的自动注射器（1），包括：细长壳体（2），其被布置成容纳具有中空针（4）的注射器（3）和塞子 6），用于密封注射器（3）并使药剂（M）移位，具有远端（D）和近端（P）的壳体（2）具有旨在施加到注射部位的孔口，其中注射器（3）相对于壳体（2）可滑动地布置，弹簧装置（8）能够在启动时：将针（4）从壳体（2）内的覆盖位置推入通过孔的先进位置并经过所述近端（P），操作所述注射器（3）以供给所述剂量的药剂（M），并且在递送所述药物（M）之后将所述注射器（3）用针（4）缩回到被覆盖位置，启动装置（20），其布置成在手动操作之前将弹簧装置（8）锁定在加压状态，并且能够在手动操作时，释放用于注射的弹簧装置（8）。弹簧装置（8）是单个压缩弹簧（8），其布置成在壳体（2）中的远端（8.1）处接地，用于推进针（4）并且用于经由柱塞（9），并且其中压缩弹簧（8）被布置成使其在壳体（2）中的接地切换到其近端（8.2）以缩回注射器（3）。

27. 发明申请

US20130112521A1 Clutch Mechanism 有权
标题翻译：离合器机构
公开(公告)号：US20130112521A1
公开(公告)日：2013-05-09
申请号：US13579339
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Yannick Hourmand
IPC分类号： F16D11/14
CPC分类号： A61M5/20 , A61M5/326 , A61M5/46 , A61M2005/206 , A61M2005/208 , A61M2005/3247 , A61M2205/581
摘要： The invention relates to a clutch mechanism for the transmission of a rotary movement from a gear arrangement comprising a first gear member and a second gear member. The first gear member is rotatable about a longitudinal axis but axially fixed wherein the first gear member, upon rotation, is arranged for translatively moving a second gear member which is prevented from rotating. The clutch mechanism comprises a circumferential shoulder arranged at the second gear member and at least one or a number of resilient clutch fingers with respective inclined inner surfaces arranged at the first gear member, the shoulder arranged for increasingly pressing against the inclined surfaces thereby flexing the clutch fingers outward when the shoulder reaches the clutch fingers in the course of its translation. The clutch mechanism further comprises tube arranged around the clutch fingers, the tube having a number of internal longitudinal splines for engaging the flexed-out clutch fingers.
摘要翻译：本发明涉及一种用于从包括第一齿轮构件和第二齿轮构件的齿轮装置传递旋转运动的离合器机构。第一齿轮构件可围绕纵向轴线旋转但是轴向固定，其中第一齿轮构件在旋转时被布置成平移地移动阻止旋转的第二齿轮构件。离合器机构包括布置在第二齿轮构件处的周向肩部和至少一个或多个弹性离合器指状物，其具有布置在第一齿轮构件处的相应的倾斜内表面，肩部设置成越来越多地压靠倾斜表面，从而使离合器当肩膀在其翻译过程中到达离合器手指时，手指向外。离合器机构还包括围绕离合器指状物布置的管，管具有用于接合弯曲离合器指的多个内部纵向花键。

28. 发明授权

US09011387B2 Force transmission arrangement for auto-injector 有权
标题翻译：自动进样器的传动装置
公开(公告)号：US09011387B2
公开(公告)日：2015-04-21
申请号：US13580146
申请日：2011-02-16
申请人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
发明人： Matthew Ekman , Timothy Donald Barrow-Williams , Thomas Mark Kemp
IPC分类号： A61M5/20 , A61M5/32 , A61M5/315 , A61M5/46 , A61M5/48 , A61M5/24 , A61M5/31
CPC分类号： A61M5/3158 , A61M5/20 , A61M5/2033 , A61M5/315 , A61M5/3202 , A61M5/326 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2418 , A61M2005/3103 , A61M2005/3152 , A61M2005/3247 , A61M2205/581 , A61M2205/583
摘要： The invention relates to a transmission arrangement for controlling a force of a translation, the transmission arrangement comprising a drive collar (13) connectable to a translative drive means (11) and prevented from rotating with respect to a ground (12) of the drive means (11), a flange face of the drive collar (13) bearing against a mating flange face of a friction collar (20), the friction collar (20) slidable in longitudinal direction and rotationally constrained by engagement in a cam track (12.3), another flange face of the friction collar (20) bearing against a mating flange face of a plunger (8), the plunger (8) slidable in longitudinal direction and prevented from rotating.
摘要翻译：本发明涉及一种用于控制平移力的传动装置，该传动装置包括可连接到平移驱动装置（11）并被阻止相对于驱动装置（12）旋转的驱动套环（13）（11），所述驱动轴环（13）的凸缘面抵靠摩擦轴环（20）的配合凸缘面，所述摩擦轴环（20）可在纵向方向上滑动并通过接合在凸轮轨道（12.3）中而被旋转地限制，，所述摩擦轴环（20）的另一凸缘面抵靠着柱塞（8）的配合凸缘面，所述柱塞（8）可沿纵向方向滑动并防止旋转。

29. 发明授权

US09789261B2 Auto-injector 有权
公开(公告)号：US09789261B2
公开(公告)日：2017-10-17
申请号：US13996321
申请日：2011-12-21
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/315
CPC分类号： A61M5/3204 , A61M5/2033 , A61M5/31583 , A61M5/326 , A61M2005/206 , A61M2005/208
摘要： An auto-injector comprising an elongate housing containing a syringe. The housing having a an orifice intended to be applied against an injection site. The syringe is slidably arranged with respect to the housing. A spring pushing the needle from a covered position into an advanced position, operating the syringe and covering the needle. An activator arranged to lock the spring prior to manual operation and capable of, upon manual operation, releasing the spring means for injection. A first gear arrangement and a second gear arrangement arranged for converting torque from a first end and a second end of the torsion spring into a translative force. The first end groundable in the housing while the second end acts on a plunger through the second gear arrangement for advancing the needle and supplying the dose.

30. 发明授权

US09205199B2 Auto-injector with needle shroud and needle protection cap 有权
标题翻译：自动进样器带针罩和针头保护帽
公开(公告)号：US09205199B2
公开(公告)日：2015-12-08
申请号：US13580271
申请日：2011-02-16
申请人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
发明人： Thomas Mark Kemp , Timothy Donald Barrow-Williams , Matthew Ekman
IPC分类号： A61M5/32 , A61M5/20 , A61M5/315 , A61M5/46 , A61M5/48 , A61M5/24 , A61M5/31 , F16H25/20
CPC分类号： A61M5/3202 , A61M5/2033 , A61M5/315 , A61M5/326 , A61M5/46 , A61M5/482 , A61M5/484 , A61M2005/206 , A61M2005/208 , A61M2005/2086 , A61M2005/2418 , A61M2005/3103 , A61M2005/3152 , A61M2005/3247 , A61M2205/581 , A61M2205/583 , F16H25/20 , F16H25/2056
摘要： An auto-injector may be used to administer a dose of a liquid medicament (M). In some embodiments, a shroud is arranged inside a housing, the shroud slidable in longitudinal direction between at least a retracted position, in which a hollow injection needle is exposable and an advanced position, in which the needle is covered by the shroud. A protective needle shield is attachable to the needle in a manner to partially protrude beyond the proximal end of the shroud through the orifice with the needle in its advanced position. A syringe carrier is arranged inside the shroud and comprises at least one snap for locking it to the shroud in order to prevent relative axial motion. The snap is configured to automatically disengage upon removal of the protective needle shield to allow the syringe and needle to be retracted into the covered position under load of the syringe spring.
摘要翻译：可以使用自动注射器来施用剂量的液体药物（M）。在一些实施例中，护罩布置在壳体内部，护罩可以在至少缩回位置（其中空心注射针可暴露于其中）和前进位置之间在纵向方向上滑动，在该位置中针被护罩覆盖。保护针护罩可以以针部分地突出超过护罩的近端通过孔口的方式附接到针上，其中针处于其前进位置。注射器托架布置在护罩内部并且包括至少一个卡扣以将其锁定到护罩上，以防止相对的轴向运动。卡扣被配置为在移除保护针护罩时自动脱离，以允许注射器和针在注射器弹簧的负载下缩回到覆盖位置。

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