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21. 发明申请

US20080058591A1 TISSUE VISUALIZATION DEVICE AND METHOD VARIATIONS 有权
标题翻译：组织可视化设备和方法变体
公开(公告)号：US20080058591A1
公开(公告)日：2008-03-06
申请号：US11848202
申请日：2007-08-30
申请人： Vahid Saadat , Chris Rothe , Edmund Tam , Ruey-Feng Peh
发明人： Vahid Saadat , Chris Rothe , Edmund Tam , Ruey-Feng Peh
IPC分类号： A61B1/01
CPC分类号： A61B1/00085 , A61B1/0008 , A61B1/00082 , A61B1/00089 , A61B1/00091 , A61B1/00177 , A61B1/005 , A61B1/012 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02007 , A61B5/6882 , A61B8/12 , A61B17/00234 , A61B17/0057 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/22012 , A61B18/24 , A61B2017/048 , A61B2017/0496
摘要： Tissue visualization devices and variations thereof are described herein where such devices may utilize a variety of methods for facilitating clearing of the device of opaque bodily fluids and sealing between the device and the underlying tissue surface. Additionally, methods and devices for enhancing navigation of the device through a patient body are also described.
摘要翻译：本文描述了组织可视化装置及其变型，其中这样的装置可以利用各种方法来促进不透明体液的装置的清除和装置与下面的组织表面之间的密封。此外，还描述了用于增强穿过患者身体的装置导航的方法和装置。

22. 发明申请

US20080058590A1 TISSUE VISUALIZATION DEVICE HAVING MULTI-SEGMENTED FRAME 审中-公开
标题翻译：具有多分辨率框架的组织可视化设备
公开(公告)号：US20080058590A1
公开(公告)日：2008-03-06
申请号：US11848193
申请日：2007-08-30
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund Tam
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund Tam
IPC分类号： A61B1/32
CPC分类号： A61B1/32 , A61B1/00085 , A61B1/005 , A61B1/041
摘要： Tissue visualization devices having multi-segmented frame are described herein where such devices may utilize multiple expanding frame members coupled to a flexible deployment catheter shaft or rigid shaft. The multiple frame members may extend distally to collapse into a low-profile configuration and may further expand or open radially to create a working field between the frame members. Moreover, the distal ends of each frame member may be tapered such that the frame members may close tightly relative to one another forming an atraumatic end. Additionally, any number of therapeutic tools can also be passed through the catheter or shaft for performing any number of procedures on the tissue for identifying, locating, and/or treating tissue.
摘要翻译：本文描述了具有多分段框架的组织可视化装置，其中这种装置可以利用联接到柔性展开导管轴或刚性轴的多个扩展框架构件。多个框架构件可以向远侧延伸以折叠成低轮廓构造，并且可以进一步扩展或径向地开放以在框架构件之间形成工作区域。此外，每个框架构件的远端可以是锥形的，使得框架构件可以相对于彼此紧密地紧密地形成形成无伤痕的端部。此外，任何数量的治疗工具也可以通过导管或轴，用于在组织上执行任何数量的程序以识别，定位和/或治疗组织。

23. 发明申请

US20080015445A1 TISSUE VISUALIZATION DEVICE AND METHOD VARIATIONS 有权
标题翻译：组织可视化设备和方法变体
公开(公告)号：US20080015445A1
公开(公告)日：2008-01-17
申请号：US11775771
申请日：2007-07-10
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund Tam , Amir Abolfathi , Chris Rothe
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund Tam , Amir Abolfathi , Chris Rothe
IPC分类号： A61B8/12
CPC分类号： A61B1/005 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/0031 , A61B5/02007 , A61B5/6882 , A61B8/12 , A61B2018/0212
摘要： Tissue visualization device and method variations are described herein where an imaging hood is temporarily sealed against a region of tissue to be treated while under direct visualization. Such a system may include a deployment catheter and an attached imaging hood deployable into an expanded configuration. The imaging hood is placed against or adjacent to the tissue to be imaged in a body linen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid is pumped into the hood until the fluid displaces any blood leaving a clear region of tissue to be imaged via all imaging element. Temporary sealing against the tissue can be achieved in a number of ways such as circumferential balloons inflatable within the hood or other sealing techniques. A field of view of the imaging element can be expanded by inflating the balloon beyond the imaging hood.
摘要翻译：本文描述了组织可视化装置和方法变化，其中成像罩在直接可视化期间临时密封待处理组织的区域。这样的系统可以包括部署导管和可展开成扩展配置的附接成像罩。成像罩被放置在通常用不透明的体液如血液填充的身体亚麻织物中或邻近要成像的组织上。半透明或透明流体被泵送到罩中，直到流体移动通过所有成像元件离开要成像的组织的清晰区域的任何血液。可以以多种方式实现对组织的临时密封，例如在罩内充气的周向气囊或其他密封技术。成像元件的视野可以通过使气囊膨胀超过成像罩而扩大。

24. 发明授权

US07736378B2 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US07736378B2
公开(公告)日：2010-06-15
申请号：US10841245
申请日：2004-05-07
申请人： Tracy D. Maahs , Richard C. Ewers , Jesus Flores , Alexander Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang C. Lam
发明人： Tracy D. Maahs , Richard C. Ewers , Jesus Flores , Alexander Khairkhahan , Ruey-Feng Peh , Vahid Saadat , Cang C. Lam
IPC分类号： A61B17/04
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This uni-directional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚定器之间的组织褶皱收紧，并且可以在一个或多个锚定器中用于收紧组织折叠。

25. 发明授权

US09468364B2 Intravascular catheter with hood and image processing systems 有权
标题翻译：血管内导管带罩和图像处理系统
公开(公告)号：US09468364B2
公开(公告)日：2016-10-18
申请号：US12618306
申请日：2009-11-13
申请人： Zachary J. Malchano , Ruey-Feng Peh , Vahid Saadat , Ted J. Cooper , David Miller , Veerappan Swaminathan
发明人： Zachary J. Malchano , Ruey-Feng Peh , Vahid Saadat , Ted J. Cooper , David Miller , Veerappan Swaminathan
IPC分类号： A61B5/00 , A61B1/05 , A61B5/042 , A61B5/0472 , A61B5/113 , A61B18/14
CPC分类号： A61B5/0084 , A61B1/05 , A61B5/01 , A61B5/0245 , A61B5/042 , A61B5/0452 , A61B5/0472 , A61B5/0538 , A61B5/113 , A61B5/6852 , A61B5/7285 , A61B5/7289 , A61B5/742 , A61B18/1492 , A61B2218/002
摘要： Image processing systems are described which utilize various methods and processing algorithms for enhancing or facilitating visual detection and/or sensing modalities for images captured in vivo by an intravascular visualization and treatment catheter. Such assemblies are configured to deliver energy, such as RF ablation, to an underlying target tissue for treatment in a controlled manner while directly visualizing the tissue during the ablation process.
摘要翻译：描述了图像处理系统，其利用各种方法和处理算法来增强或促进通过血管内可视化和治疗导管在体内捕获的图像的视觉检测和/或感测模态。这样的组件被配置为将能量（例如RF消融）传递到潜在的目标组织，以受控的方式进行治疗，同时在消融过程中直接使组织可视化。

26. 发明授权

US08934962B2 Electrophysiology mapping and visualization system 有权
标题翻译：电生理测绘和可视化系统
公开(公告)号：US08934962B2
公开(公告)日：2015-01-13
申请号：US11848532
申请日：2007-08-31
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam
IPC分类号： A61B5/00 , A61B17/34 , A61B1/00 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/02 , A61B5/042 , A61B17/12 , A61B19/00 , A61B8/12 , A61B8/00 , A61B17/04 , A61B17/221 , A61B18/02 , A61B17/00 , A61B17/22 , A61B18/00
CPC分类号： A61B5/0084 , A61B1/0008 , A61B1/00082 , A61B1/00085 , A61B1/00089 , A61B1/005 , A61B1/015 , A61B1/018 , A61B1/04 , A61B5/0031 , A61B5/02007 , A61B5/0422 , A61B5/6882 , A61B8/12 , A61B8/4472 , A61B17/0487 , A61B17/12045 , A61B17/221 , A61B17/3415 , A61B17/3423 , A61B18/02 , A61B34/20 , A61B34/30 , A61B90/36 , A61B2017/00044 , A61B2017/00053 , A61B2017/00296 , A61B2017/003 , A61B2017/00575 , A61B2017/0409 , A61B2017/0477 , A61B2017/12127 , A61B2017/22038 , A61B2017/22054 , A61B2017/22067 , A61B2017/22069 , A61B2017/22082 , A61B2017/3445 , A61B2017/3484 , A61B2017/3488 , A61B2018/00982 , A61B2018/0212 , A61B2034/107 , A61B2034/2051 , A61B2034/301 , A61B2090/306 , A61B2090/309 , A61B2090/3614 , A61B2090/373 , A61B2090/3958 , A61M5/007
摘要： Electrophysiology mapping and visualization systems are described herein where such devices may be used to visualize tissue regions as well as map the electrophysiological activity of the tissue. Such a system may include a deployment catheter and an attached hood deployable into an expanded configuration. In use, the imaging hood is placed against or adjacent to a region of tissue to be imaged in a body lumen that is normally filled with an opaque bodily fluid such as blood. A translucent or transparent fluid, such as saline, can be pumped into the imaging hood until the fluid displaces any blood, thereby leaving a clear region of tissue to be imaged via an imaging element in the deployment catheter. A position of the catheter and/or hood may be tracked and the hood may also be used to detect the electrophysiological activity of the visualized tissue for mapping.
摘要翻译：本文描述了电生理学测绘和可视化系统，其中这样的装置可用于可视化组织区域以及映射组织的电生理活性。这样的系统可以包括部署导管和可展开成展开配置的连接的罩。在使用中，成像罩被放置在通常填充有不透明体液如血液的体腔中的待成像组织区域附近或邻近。半透明或透明的液体（例如盐水）可被泵送到成像罩中，直到流体移动任何血液，从而留下通过展开导管中的成像元件成像的组织的清晰区域。可以跟踪导管和/或罩的位置，并且罩也可用于检测可视化组织的电生理活动以进行映射。

27. 发明授权

US08087413B2 Attenuation of environmental parameters on a gastric lumen 有权
标题翻译：胃管内环境参数的衰减
公开(公告)号：US08087413B2
公开(公告)日：2012-01-03
申请号：US11035702
申请日：2005-01-14
申请人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
发明人： Vahid Saadat , Ruey-Feng Peh , Richard C. Ewers , Eugene G. Chen
IPC分类号： A61B19/00 , A61B17/08 , A61B17/04 , A61F2/04 , A61L17/00
CPC分类号： A61B17/0469 , A61B17/00491 , A61B17/0401 , A61B17/0487 , A61B17/1114 , A61B2017/00349 , A61B2017/00495 , A61B2017/0406 , A61B2017/0454 , A61B2017/0464
摘要： The attenuation or isolation of environmental parameters on a gastric lumen is described herein. Once tissue plications are formed into a gastric lumen or sleeve within a stomach, the newly formed lumen is subjected to a multitude of fluctuating stresses or pressure from food or fluids passing therethrough, from naturally-occurring contractions, and/or from changes in pH levels from caustic stomach acids and hormones. The tissue interface between these plications can be isolated from such environmental fluctuations, or the fluctuations can be attenuated, by a number of methods. One example is to place a gastric stent or sleeve within the newly formed lumen. Another example is to utilize multiple rows of anchors, clips, or sutures along the interface. Alternatively, bio-adhesives can be dispensed to buttress the tissue interface. In another variation, the tissue can be approximated in different configurations which effectively reduce or isolate the adhered tissue region.
摘要翻译：本文描述了在胃腔上的环境参数的衰减或分离。一旦组织消融在胃内形成胃腔或套管，则新形成的内腔经受来自通过其的食物或液体的多种波动的应力或压力，从天然存在的收缩和/或pH水平的变化从苛性胃酸和激素。可以通过多种方法将这些斑点之间的组织界面与这种环境波动隔离，或者波动可以减弱。一个例子是将胃支架或套管放置在新形成的内腔内。另一个例子是沿着界面使用多行锚，剪辑或缝线。或者，可以分配生物粘合剂以支撑组织界面。在另一个实施方式中，可以以有效地减少或隔离粘附的组织区域的不同配置来近似组织。

28. 发明申请

US20080214889A1 METHODS AND APPARATUS FOR PREVENTING TISSUE MIGRATION 审中-公开
标题翻译：防止组织移植的方法和装置
公开(公告)号：US20080214889A1
公开(公告)日：2008-09-04
申请号：US11877386
申请日：2007-10-23
申请人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam , Chris A. Rothe
发明人： Vahid Saadat , Ruey-Feng Peh , Edmund A. Tam , Chris A. Rothe
IPC分类号： A61B17/295 , A61B1/313 , A61B17/34
CPC分类号： A61B17/02 , A61B1/00089 , A61B1/005 , A61B1/3137 , A61B6/503 , A61B8/0883 , A61B17/3439 , A61B2017/0237
摘要： Methods and apparatus for preventing tissue migration or tissue “tenting” during transseptal access procedures are described. The underlying tissue wall may be temporarily engaged via any number of mechanisms, e.g., engaging teeth or projections, threaded needle, vacuum, etc., and one or more instruments may be passed through the tissue wall while maintaining engagement with the tissue to provide a counter-traction force. The procedure may be accomplished while under direct visualization within an imaging hood placed against the tissue surface and purged of blood.
摘要翻译：描述了在经验过程中防止组织移动或组织“隆起”的方法和装置。下面的组织壁可以通过任何数量的机构临时接合，例如，接合的齿或突起，螺纹针，真空等，并且一个或多个器械可以通过组织壁，同时保持与组织的接合，以提供反牵引力。该过程可以在在靠着组织表面放置并被清除血液的成像罩内直接可视化的情况下完成。

29. 发明申请

US20050277945A1 Apparatus and methods for performing transluminal gastrointestinal procedures 有权
标题翻译：用于执行经腔胃肠道手术的装置和方法
公开(公告)号：US20050277945A1
公开(公告)日：2005-12-15
申请号：US10918217
申请日：2004-08-11
申请人： Vahid Saadat , Ruey-Feng Peh
发明人： Vahid Saadat , Ruey-Feng Peh
IPC分类号： A61B17/00 , A61B17/06 , A61B17/10
CPC分类号： A61B17/06166 , A61B2017/00278 , A61B2017/00349 , A61B2017/00761 , A61B2017/06057 , A61B2017/06176
摘要： Methods and apparatus are provided for diagnosing and treating digestive or other organs (as well as other parts of the body) endoluminally and transluminally, via instruments passed into the GI tract per-orally and/or per-anally. The instruments may, for example, pass transluminally out of the stomach and/or the colon through a breach formed therein in order to conduct diagnostic or therapeutic procedures, such as gastroenterostomy.
摘要翻译：提供方法和装置，用于通过口服和/或每次通过胃肠道的器械来诊断和治疗消化系统或其他器官（以及身体其他部位）。例如，器械可以通过其中形成的破裂从胃和/或结肠中透明地通过，以进行诊断或治疗程序，例如胃肠造口术。

30. 发明申请

US20050251157A1 Apparatus and methods for positioning and securing anchors 有权
标题翻译：用于定位和固定锚固件的装置和方法
公开(公告)号：US20050251157A1
公开(公告)日：2005-11-10
申请号：US10840950
申请日：2004-05-07
申请人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
发明人： Vahid Saadat , Tracy Maahs , Richard Ewers , Marvin Elmers , Jesus Flores , Alex Khairkhahan , Ruey-Feng Peh , Cang Lam
IPC分类号： A61B17/00 , A61B17/04 , A61B17/06 , A61B17/064 , A61B17/08 , A61B17/10 , A61B17/28 , A61B17/34
CPC分类号： A61B17/08 , A61B17/0401 , A61B17/0469 , A61B17/0487 , A61B17/06066 , A61B17/064 , A61B17/10 , A61B17/29 , A61B2017/00867 , A61B2017/0404 , A61B2017/0409 , A61B2017/0417 , A61B2017/0419 , A61B2017/0445 , A61B2017/0446 , A61B2017/045 , A61B2017/0451 , A61B2017/0454 , A61B2017/0456 , A61B2017/0458 , A61B2017/0459 , A61B2017/0461 , A61B2017/0462 , A61B2017/0464 , A61B2017/0475 , A61B2017/0488 , A61B2017/0496 , A61B2017/06052 , A61B2017/081 , A61B2017/3488 , Y10T24/39 , Y10T24/3936
摘要： Apparatus and methods for positioning and securing anchors are disclosed herein. The anchors are adapted to be delivered and implanted into or upon tissue, particularly tissue within the gastrointestinal system of a patient. The anchor is adapted to slide uni-directionally over suture such that a tissue plication may be cinched between anchors. A locking mechanism either within the anchor itself of positioned proximally of the anchor may allow for the uni-directional translation while enabling the anchor to be locked onto the suture if the anchor is pulled, pushed, or otherwise urged in the opposite direction along the suture. This unidirectional anchor locking mechanism facilitates the cinching of the tissue plication between the anchors and it may be utilized in one or several anchors in cinching a tissue fold.
摘要翻译：本文公开了用于定位和固定锚固件的装置和方法。锚固件适于被递送并植入到组织中，特别是患者胃肠系统内的组织中。锚固件适于在缝合线上单向滑动，使得组织褶皱可以在锚固件之间束紧。如果锚固件被拉动，推动或沿着缝合线沿相反方向被推动，锚固件本身内的定位器本身内的锁定机构可以允许单向平移，同时使锚固件能够锁定在缝合线上。这种单向锚定锁定机构有助于锚固件之间的组织褶皱的收紧，并且可以在一个或多个锚固件中使用紧固组织褶皱。

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