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21. 发明授权

US07368273B2 Alkaline protease 有权
标题翻译：碱性蛋白酶
公开(公告)号：US07368273B2
公开(公告)日：2008-05-06
申请号：US10385662
申请日：2003-03-12
申请人： Mitsuyoshi Okuda , Tsuyoshi Sato , Kazuhiro Saito , Nobuyuki Sumitomo , Yoshifumi Izawa , Katsuhisa Saeki , Tohru Kobayashi , Masafumi Nomura
发明人： Mitsuyoshi Okuda , Tsuyoshi Sato , Kazuhiro Saito , Nobuyuki Sumitomo , Yoshifumi Izawa , Katsuhisa Saeki , Tohru Kobayashi , Masafumi Nomura
IPC分类号： C12N9/48 , C11D3/386
CPC分类号： C11D3/386 , C12N9/54 , C12Y304/21062
摘要： An alkaline protease wherein an amino acid residue at (a) position 65, (b) position 101, (c) position 163, (d) position 17-0, (e) position 171, (f) position 273, (g) position 320, (h) position 359 or (i) position 387 of SEQ. ID NO: 2 or at a position corresponding thereto has been selected from the following amino acid residues: position (a): proline, position (b): asparagine, position (e): histidine, aspartic acid, phenylalanine, lysine, asparagine, seine, isoleucine, leucine, glutamine, threonine and valine, position (d): valine and leucine, position (e): alanine, glutamic acid, glycine and threonine, position (K): isoleucine, glycine and threonine, position (g): phenylalanine, valine, threonine, leucine, isoleucine and glycine, position (h): seine, leucine, valine, isoleucine and glutamine, position (i): alanine, lysine, glutamine, glutamic acid, arginine and histidine. A method to an alkaline protease having activity even in the presence of a highly concentrated fatty acid, and exhibiting excellent detergency for the removal of a complex stain containing protein, sebum and the like, and therefore useful as an ingredient in a detergent.
摘要翻译：（a）位置65，（b）位置101，（c）位置163，（d）位置17-0，（e）位置171，（f）位置273，（g）位置320，（h）位置359或（i）SEQ ID NO：位置（a）：脯氨酸，位置（b）：天冬酰胺，位置（e）：组氨酸，天冬氨酸，苯丙氨酸，赖氨酸，天冬酰胺，（e）：丙氨酸，谷氨酸，甘氨酸和苏氨酸，位置（K）：异亮氨酸，甘氨酸和苏氨酸，位置（g）：缬氨酸和亮氨酸，（i）：丙氨酸，赖氨酸，谷氨酰胺，谷氨酸，精氨酸和组氨酸，位置（h）：ine碱，亮氨酸，缬氨酸，异亮氨酸和谷氨酰胺。一种碱性蛋白酶的方法，即使在高度浓缩的脂肪酸的存在下也具有活性，并且对于去除含有蛋白质，皮脂等的复合污渍具有优异的去污力，因此可用作洗涤剂中的成分。

22. 发明授权

US07182531B2 Developing method and apparatus 失效
标题翻译：开发方法和装置
公开(公告)号：US07182531B2
公开(公告)日：2007-02-27
申请号：US11476574
申请日：2006-06-29
申请人： Kiyohisa Tateyama , Masafumi Nomura , Taketora Shinogi
发明人： Kiyohisa Tateyama , Masafumi Nomura , Taketora Shinogi
IPC分类号： G03D5/00
CPC分类号： G03D3/065 , G03D3/06 , G03F7/30 , G03F7/3071 , H01L21/6715 , H01L21/67253
摘要： In this developing method and apparatus, a concentration measuring unit 222 picks part of developing fluid in a blending tank 186 to measure the resist concentration by an absorption photometry and feeds the detected resist concentration to a control unit 240. The control unit 240 controls respective valves 210, 212, 216 of a TMAH concentrate solution 200, a solvent pipe 204 and a drain pipe 208 in a manner that the developing fluid in the blending tank 186 has a TMAH concentration corresponding to a measured resist-concentration value to accomplish a constant developing rate, performing component control of the developing fluid. The developing fluid transferred from the blending tank 186 to a supply tank 188 is fed to a developer nozzle DN in a developing section 126 through a developer pipe 224 owing to the drive of a pump 228. Accordingly, even if the developing fluid is reused in the developing process in multiple times, it is possible to make sure of the uniformity in development.
摘要翻译：在该显影方法和装置中，浓度测量单元222拾取混合罐186中的显影液的一部分，通过吸收测光法测量抗蚀剂浓度，并将检测到的抗蚀剂浓度输送到控制单元240.控制单元240控制各个阀 210,212,216的TMAH浓缩液200，溶剂管204和排水管208，使得混合罐186中的显影液具有对应于测量的抗蚀剂浓度值的TMAH浓度，以实现恒定显影速率，执行显影液的成分控制。从混合罐186输送到供给罐188的显影液由于泵228的驱动而通过显影管224被供给到显影部126中的显影剂喷嘴DN。因此，即使显影液再利用发展过程多次，有可能确保发展的一致性。

23. 发明申请

US20060246384A1 Developing method and apparatus 失效
标题翻译：开发方法和装置
公开(公告)号：US20060246384A1
公开(公告)日：2006-11-02
申请号：US11476574
申请日：2006-06-29
申请人： Kiyohisa Tateyama , Masafumi Nomura , Taketora Shinogi
发明人： Kiyohisa Tateyama , Masafumi Nomura , Taketora Shinogi
IPC分类号： G03C1/005
CPC分类号： G03D3/065 , G03D3/06 , G03F7/30 , G03F7/3071 , H01L21/6715 , H01L21/67253
摘要： In this developing method and apparatus, a concentration measuring unit 222 picks part of developing fluid in a blending tank 186 to measure the resist concentration by an absorption photometry and feeds the detected resist concentration to a control unit 240. The control unit 240 controls respective valves 210, 212, 216 of a TMAH concentrate solution 200, a solvent pipe 204 and a drain pipe 208 in a manner that the developing fluid in the blending tank 186 has a TMAH concentration corresponding to a measured resist-concentration value to accomplish a constant developing rate, performing component control of the developing fluid. The developing fluid transferred from the blending tank 186 to a supply tank 188 is fed to a developer nozzle DN in a developing section 126 through a developer pipe 224 owing to the drive of a pump 228. Accordingly, even if the developing fluid is reused in the developing process in multiple times, it is possible to make sure of the uniformity in development.
摘要翻译：在该显影方法和装置中，浓度测量单元222拾取混合罐186中的显影液的一部分，通过吸收测光法测量抗蚀剂浓度，并将检测到的抗蚀剂浓度输送到控制单元240.控制单元240控制各个阀 210,212,216的TMAH浓缩液200，溶剂管204和排水管208，使得混合罐186中的显影液具有对应于测量的抗蚀剂浓度值的TMAH浓度，以实现恒定显影速率，执行显影液的成分控制。从混合罐186输送到供给罐188的显影液由于泵228的驱动而通过显影管224被供给到显影部126中的显影剂喷嘴DN。因此，即使显影液再利用发展过程多次，有可能确保发展的一致性。

24. 发明授权

US06210147B1 Method of and apparatus for shaping fibrous elastic body 有权
标题翻译：纤维弹性体成型方法及装置
公开(公告)号：US06210147B1
公开(公告)日：2001-04-03
申请号：US09129014
申请日：1998-08-04
申请人： Takayasu Mori , Masafumi Nomura , Masanao Yamaguchi
发明人： Takayasu Mori , Masafumi Nomura , Masanao Yamaguchi
IPC分类号： A01J2512
CPC分类号： D04H1/60 , B29C43/006 , B29C43/14 , B29C43/34 , B29C2043/148 , B29C2043/3488 , B29K2105/0809 , B29K2105/12 , B29K2105/25 , B29K2503/00 , B29L2031/3041 , D04H1/541 , D04H1/558
摘要： This invention relates to an apparatus and method for shaping fibrous elastic bodies. The apparatus includes a preliminary shaping die and a final shaping die. A fiber material, which includes a binder fiber and a matrix fiber, is used to form the elastic bodies. The binder fiber has a lower melting point than the matrix fiber. The fiber material is placed into the preliminary shaping die and half melted to bond the unmelted matrix fiber and thereby form the preliminary shaped item. The preliminary shaped item has a preliminary shape of an objective article to be shaped. The preliminary shaped item is then transferred to the final shaping die, in which it is further heated and clamped to shape the objective article.
摘要翻译：本发明涉及一种成形纤维弹性体的装置和方法。该装置包括预成型模和最终成形模。使用包含粘合纤维和基质纤维的纤维材料来形成弹性体。粘合纤维的熔点比基体纤维低。将纤维材料放入预成型模中，半熔融粘合未熔化的基质纤维，从而形成预成型品。预成型品具有待成形的客观物品的初步形状。然后将预成型物品转移到最终成型模具中，其中进一步加热和夹紧以使物品成型。

25. 发明授权

US6159541A Spin coating process 失效
标题翻译：旋涂工艺
公开(公告)号：US6159541A
公开(公告)日：2000-12-12
申请号：US182414
申请日：1998-10-30
申请人： Mitsuhiro Sakai , Hideyuki Takamori , Masafumi Nomura
发明人： Mitsuhiro Sakai , Hideyuki Takamori , Masafumi Nomura
IPC分类号： B05C13/02 , B05C11/08 , B05D1/00 , B05D1/40 , B05D3/12 , G03F7/16 , H01L21/00
CPC分类号： H01L21/6715 , B05C11/08 , B05D1/005 , G03F7/162
摘要： A coating process comprises the steps of (a) holding a substrate using a spin chuck surrounded by inner and outer cups, such that the substrate can rotate, (b) rotating the substrate by rotating the spin chuck, and applying a coating liquid onto the substrate, thereby forming a coating on the substrate, (c) discharging, from the inner and outer cups, that part of the coating liquid which is scattered from the substrate while the substrate is rotated, (d) exhausting the inner and outer cups through a plurality of exhaust ports formed in outer peripheral portions of the outer cup, and (e) reducing, from a peripheral region of the substrate, the mist of the coating liquid which has occurred during the step (b), before the substrate stops rotation.
摘要翻译：涂覆方法包括以下步骤：（a）使用由内杯和外杯围绕的旋转卡盘保持基底，使得基底可以旋转，（b）通过旋转旋转卡盘旋转基底，并将涂布液施加到从而在基板上形成涂层，（c）从内杯和外杯排出在基板旋转时从基板散射的涂布液的一部分，（d）将内杯和外杯排出形成在所述外杯的外周部的多个排气口，以及（e）在所述基板停止旋转之前，从所述基板的周边区域减少所述步骤（b）中发生的所述涂布液的雾。

26. 发明授权

US5871584A Processing apparatus and processing method 失效
标题翻译：处理装置及处理方法
公开(公告)号：US5871584A
公开(公告)日：1999-02-16
申请号：US929106
申请日：1997-09-15
申请人： Kiyohisa Tateyama , Masafumi Nomura , Takayuki Tomoeda
发明人： Kiyohisa Tateyama , Masafumi Nomura , Takayuki Tomoeda
IPC分类号： G03F7/30 , B05C5/02 , B05C11/08 , B05C11/10 , H01L21/02 , H01L21/027 , B05B3/00 , B08B3/00
CPC分类号： B05C11/1039 , G03F7/3021 , B05C11/08 , B05C5/0208 , Y10S134/902
摘要： A develop processing apparatus is provided for processing an object with a developing solution, comprising a retaining member for rotatably retaining the object, a developing solution supply nozzle for supplying the developing solution to the object, a developing solution sucking nozzle for sucking the developing solution supplied to the object, a developing solution supply nozzle moving mechanism for moving the developing solution supply nozzle above the object, a developing solution sucking nozzle moving mechanism for moving the developing solution sucking nozzle above the object. After the developing solution is supplied to the object subsequent to moving the developing solution supply nozzle, the developing solution sucking nozzle is moved and the developing solution on the object is sucked.
摘要翻译：一种显影处理装置，用于处理具有显影液的物体，包括用于可旋转地保持物体的保持构件，用于将显影液供给到物体的显影液供给喷嘴，用于吸取供给的显影液的显影液吸嘴本发明的目的是提供一种用于使显影液供给喷嘴在物体上方移动的显影液供给喷嘴移动机构，用于将显影液吸引喷嘴移动到物体上方的显影液吸引喷嘴移动机构。在显影液供给喷嘴移动之后向显影液供给显影液后，使显影液吸引喷嘴移动，并将吸收对象物的显影液。

27. 发明授权

US5815762A Processing apparatus and processing method 失效
标题翻译：处理装置及处理方法
公开(公告)号：US5815762A
公开(公告)日：1998-09-29
申请号：US878960
申请日：1997-06-19
申请人： Mitsuhiro Sakai , Masafumi Nomura , Kazuaki Tsunoda
发明人： Mitsuhiro Sakai , Masafumi Nomura , Kazuaki Tsunoda
IPC分类号： B05C11/08 , G03D5/04 , G03F7/16 , G03F7/30
CPC分类号： G03D5/04 , B05C11/08 , G03F7/3021 , G03F7/16 , Y10S134/902
摘要： A development processing apparatus includes a processing unit for storing a substrate S and a processing solution supply nozzle arranged above the substrate S stored in the processing unit. A processing solution storage is formed inside the supply nozzle. A supply passage for supplying the processing solution into the solution storage is connected to the supply nozzle. A plurality of eject holes for ejecting the processing solution in the solution storage are formed in a lower surface of the supply nozzle. In this processing apparatus, the upper surface of the solution storage consists of at least one inclined surface, and an exhaust port is formed in a high portion of the inclined surface.
摘要翻译：显影处理装置包括：处理单元，用于存储设置在处理单元中的基板S上方的基板S和处理液供给喷嘴。在供给喷嘴内部形成有处理液储存部。用于将处理溶液供应到溶液储存器中的供应通道连接到供应喷嘴。在供给喷嘴的下表面形成有用于将溶液储存部中的处理液喷出的多个排出孔。在该处理装置中，溶液储存器的上表面由至少一个倾斜表面构成，并且排出口形成在倾斜表面的高部分中。

28. 发明授权

US07863235B2 Method of activating α-amylase with oxidizing agents 失效
标题翻译：用氧化剂活化α-淀粉酶的方法
公开(公告)号：US07863235B2
公开(公告)日：2011-01-04
申请号：US11296423
申请日：2005-12-08
申请人： Yoko Ishii , Masafumi Nomura , Shitsuu Shikata
发明人： Yoko Ishii , Masafumi Nomura , Shitsuu Shikata
IPC分类号： C11D3/38 , C11D3/00 , C12N9/26
CPC分类号： C12N9/2417 , C11D3/38609 , C11D3/3942 , C12N9/2414
摘要： The invention provides an activation method of α-amylase. α-Amylase or particles containing the same are contacted with an oxidizing agent or particles containing the same. After contacting, the activated α-amylase can be separated from the oxidizing agent. After contacting, α-amylase and the oxidizing agent can be incorporated in the form of a mixture into a detergent base to give a detergent composition.
摘要翻译：本发明提供α-淀粉酶的活化方法。将含有该α-淀粉酶或含有该α-淀粉酶的颗粒与氧化剂或含有它们的颗粒接触。接触后，可将活化的α-淀粉酶与氧化剂分离。接触后，可以将α-淀粉酶和氧化剂以混合物的形式并入洗涤剂基质中，得到洗涤剂组合物。

29. 发明申请

US20080177040A1 ALKALINE PROTEASE 有权
标题翻译：碱性蛋白酶
公开(公告)号：US20080177040A1
公开(公告)日：2008-07-24
申请号：US12049022
申请日：2008-03-14
申请人： Mitsuyoshi Okuda , Tsuyoshi Sato , Kazuhiro Saito , Nobuyuki Sumitomo , Yoshifumi Izawa , Katsuhisa Saeki , Tohru Kobayashi , Masafumi Nomura
发明人： Mitsuyoshi Okuda , Tsuyoshi Sato , Kazuhiro Saito , Nobuyuki Sumitomo , Yoshifumi Izawa , Katsuhisa Saeki , Tohru Kobayashi , Masafumi Nomura
IPC分类号： C07K2/00
CPC分类号： C11D3/386 , C12N9/54 , C12Y304/21062
摘要： Provided in the present invention is an alkaline protease wherein an amino acid residue at (a) position 65, (b) position 101, (c) position 163, (d) position 170, (e) position 171, (f) position 273, (g) position 320, (h) position 359 or (i) position 387 of SEQ. ID NO:1 or at a position corresponding thereto has been selected from the following amino acid residues: position (a): proline, position (b): asparagine, position (c): histidine, aspartic acid, phenylalanine, lysine, asparagine, serine, isoleucine, leucine, glutamine, threonine and valine, position (d): valine and leucine, position (e): alanine, glutamic acid, glycine and threonine, position (f): isoleucine, glycine and threonine, position (g): phenylalanine, valine, threonine, leucine, isoleucine and glycine, position (h): serine, leucine, valine, isoleucine and glutamine, position (i): alanine, lysine, glutamine, glutamic acid, arginine and histidine.The present invention makes it possible to efficiently produce and provide alkaline proteases having activity even in the presence of a highly concentrated fatty acid, and exhibiting excellent detergency for the removal of a complex stain containing protein, sebum and the like, and therefore being useful as an enzyme to be incorporated in a detergent.
摘要翻译：在本发明中提供的是碱性蛋白酶，其中（a）位置65，（b）位置101，（c）位置163，（d）位置170，（e）位置171，（f），（g）位置320，（h）位置359或（i）SEQ ID NO：位置（a）：脯氨酸，位置（b）：天冬酰胺，位置（c）：组氨酸，天冬氨酸，苯丙氨酸，赖氨酸，天冬酰胺，位置（d）：缬氨酸和亮氨酸，位置（e）：丙氨酸，谷氨酸，甘氨酸和苏氨酸，位置（f）：异亮氨酸，甘氨酸和苏氨酸，位置（g）位置（h）：丝氨酸，亮氨酸，缬氨酸，异亮氨酸和谷氨酰胺，位置（i）：丙氨酸，赖氨酸，谷氨酰胺，谷氨酸，精氨酸和组氨酸，位置（h）：缬氨酸，缬氨酸，苏氨酸，亮氨酸，异亮氨酸和甘氨酸。本发明使得可以有效地生产和提供具有活性的碱性蛋白酶，即使在高度浓缩的脂肪酸的存在下也具有优异的去污力来去除含有蛋白质，皮脂等的复合污渍，因此可用作要掺入洗涤剂中的酶。

30. 发明授权

US07101698B2 Alkaline protease 有权
标题翻译：碱性蛋白酶
公开(公告)号：US07101698B2
公开(公告)日：2006-09-05
申请号：US10456479
申请日：2003-06-09
申请人： Tsuyoshi Sato , Mitsuyoshi Okuda , Yasushi Takimura , Nobuyuki Sumitomo , Masafumi Nomura , Tohru Kobayashi
发明人： Tsuyoshi Sato , Mitsuyoshi Okuda , Yasushi Takimura , Nobuyuki Sumitomo , Masafumi Nomura , Tohru Kobayashi
IPC分类号： C12N9/54 , C12N15/74 , C12P21/00 , C07K14/32
CPC分类号： C07H21/04 , C12N9/54
摘要： The present invention relates to an alkaline protease having a prepro sequence, wherein the prepro sequence is a mutant sequence of the amino acid sequence of SEQ ID NO: 1 or an amino acid sequence having 80% or higher homology to the amino acid sequence of SEQ ID NO: 1, in which amino acid residues at (a) position 52, (b) position 75, and (c) position 142 of SEQ ID NO: 1, or amino acid residues at positions corresponding to these positions are substituted by the following amino acid residues: at position (a): aspartic acid or arginine, at position (b): alanine or arginine, and at position (c): lysine; and the alkaline protease, when in a mature form, has the amino acid sequence of SEQ ID NO: 2 or an amino acid sequence having a homology of 80% or higher to this amino acid sequence. The present invention also relates to, for example, a gene encoding the alkaline protease. According to the present invention, an alkaline protease increased in production can be produced. In particular, there can be efficiently produced an alkaline protease having an activity even in the presence of a fatty acid of high concentration and exhibiting excellent detergency against complex soils containing proteins and sebum.
摘要翻译：本发明涉及具有前序列的碱性蛋白酶，其中前序列是SEQ ID NO：1的氨基酸序列的突变序列或与SEQ ID NO：1的氨基酸序列具有80％以上同源性的氨基酸序列 SEQ ID NO：1的（a）位置52，（b）位置75和（c）位置142处的氨基酸残基或对应于这些位置的位置处的氨基酸残基被替换为SEQ ID NO：以下氨基酸残基：位置（a）：天冬氨酸或精氨酸，位置（b）：丙氨酸或精氨酸，和位置（c）：赖氨酸; 碱性蛋白酶以成熟形式具有SEQ ID NO：2的氨基酸序列或与该氨基酸序列同源性为80％以上的氨基酸序列。本发明还涉及例如编码碱性蛋白酶的基因。根据本发明，可以生产生产中增加的碱性蛋白酶。特别是，即使在高浓度的脂肪酸的存在下也能够有效地生成具有活性的碱性蛋白酶，并且对于含有蛋白质和皮脂的复杂土壤表现出优异的去污力。

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