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    • 22. 发明授权
    • Chemical compounds
    • 化合物
    • US08357816B2
    • 2013-01-22
    • US12841586
    • 2010-07-22
    • Josef EhrenfreundPierre Joseph Marcel JungHans ToblerHarald Walter
    • Josef EhrenfreundPierre Joseph Marcel JungHans ToblerHarald Walter
    • C07F7/10
    • C07F7/0812A01N55/00
    • A fungicidal compound of formula (I): where Het is a 5- or 6-membered heterocyclic ring containing one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, the ring being substituted by groups R7, R8 and R9; R1 is hydrogen, optionally substituted (C1-4alkyl, optionally substituted (C1-4alkylC(═O), optionally substituted (C1-4alkylC(═O)O, optionally substituted (C1-4)alkoxy(C1-4)alkyl, optionally substituted allyl, optionally substituted propargyl or optionally substituted allenyl; R2, R3, R4 and R5 are each, independently, hydrogen, halogen, optionally substituted (C1-4)alkyl, optionally substituted (C1-4)alkoxy or optionally substituted (C1-4)alkoxy(C1-4alkyl; R6 is an organic group containing three to thirteen carbon atoms and at least one silicon atom and, optionally, one to three heteroatoms, each independently selected from oxygen, nitrogen and sulphur, and is optionally substituted by one to four independently selected halogen atoms; R7, R8 and R9 are each, independently, hydrogen, halogen, C1-3 alkyl, C1-3 haloalkyl, C1-3alkoxy(C1-3)alkyl or cyano, where at least one of R7, R8 and R9 is not hydrogen; and X is O or S; or an N-oxide thereof; and when present, each optional substituent on alkyl moieties, allyl, propargyl and allenyl is, independently, selected from halogen, hydroxy, cyano, methoxycarbonyl, ethoxycarbonyl, methoxy, ethoxy, methylsulfonyl, ethylsulfonyl, difluoromethoxy, trifluoromethoxy and trifluorothiomethoxy.
    • 式(I)的杀真菌化合物:其中Het是含有一至三个杂原子的5-或6-元杂环,各自独立地选自氧,氮和硫,该环被R7,R8和R9基团取代; 任选取代的(C 1-4烷基,(C 1-4)C(= O),任选取代的(C 1-4烷基C(= O)O),任选取代的(C 1-4)烷氧基(C 1-4) 取代的烯丙基,任选取代的炔丙基或任选取代的烯丙基; R 2,R 3,R 4和R 5各自独立地为氢,卤素,任选取代的(C 1-4)烷基,任选取代的(C 1-4)烷氧基或任选取代的 4)烷氧基(C 1-4烷基; R 6是含有三至十三个碳原子和至少一个硅原子的有机基团,以及任选的一至三个杂原子,各自独立地选自氧,氮和硫,并且任选地被一个 至四个独立选择的卤素原子; R 7,R 8和R 9各自独立地为氢,卤素,C 1-3烷基,C 1-3卤代烷基,C 1-3烷氧基(C 1-3)烷基或氰基,其中R 7, R8和R9不是氢; X是O或S;或其N-氧化物;当存在时,每个任选的取代基 羟基,氰基,甲氧基羰基,乙氧基羰基,甲氧基,乙氧基,甲基磺酰基,乙基磺酰基,二氟甲氧基,三氟甲氧基和三氟硫代甲氧基,独立地选自烷基部分,烯丙基,炔丙基和烯丙基。