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21. 发明申请

US20110207619A1 ARRANGEMENT FOR PROCESSING A PLURALITY OF SAMPLES FOR ANALYSIS 审中-公开
标题翻译：处理多样化分析样本的安排
公开(公告)号：US20110207619A1
公开(公告)日：2011-08-25
申请号：US12448015
申请日：2007-11-29
申请人： Thomas Ehben , Mitja Schonecke , Christian Zilch
发明人： Thomas Ehben , Mitja Schonecke , Christian Zilch
IPC分类号： C40B30/04 , C40B60/04
CPC分类号： B01L9/527 , B01L2300/021 , G01N35/04
摘要： An arrangement is provided in at least one embodiment, having a magazine for supplying a plurality of microfluidic devices. The microfluidic devices each contain at least one element/device for binding at least one biological molecule, wherein the at least one element/device for binding the at least one biological molecule can be moved relative to the microfluidic device. A sample presumably containing biological molecules to be examined is introduced into the microfluidic device. The biological molecule to be examined is bound by the at least one element/device for binding the biological molecule. In at least one embodiment, the at least one element/device for binding the at least one biological molecule, or the substrate-molecule complex, can then be moved in the microfluidic device, e.g. in accordance with a predetermined reaction sequence, for example by means of a magnetic field. The microfluidic device is transported through the arrangement.
摘要翻译：在至少一个实施例中提供了一种布置，其具有用于供应多个微流体装置的盒。微流体装置各自包含用于结合至少一个生物分子的至少一个元件/装置，其中用于结合至少一个生物分子的至少一个元件/装置可以相对于微流体装置移动。将含有待检测的生物分子的样品引入微流体装置。待检测的生物分子被至少一个用于结合生物分子的元件/装置结合。在至少一个实施方案中，用于结合至少一个生物分子或底物 - 分子复合物的至少一种元件/装置然后可以在微流体装置中移动，例如，根据预定的反应顺序，例如借助于磁场。微流体装置通过该装置输送。

22. 发明授权

US08812341B2 Method and system for optimizing process models 有权
标题翻译：优化流程模型的方法和系统
公开(公告)号：US08812341B2
公开(公告)日：2014-08-19
申请号：US13268166
申请日：2011-10-07
申请人： Thomas Ehben , Stefan Horn , Thilo Tetzner
发明人： Thomas Ehben , Stefan Horn , Thilo Tetzner
IPC分类号： G06F17/00
CPC分类号： G05B17/02 , G06Q10/04 , G06Q10/0633
摘要： Within methods and systems for computer-aided optimization of process models, defined specifications and associated release criteria (quality gates) are available for every work stage. The specifications include service documents, result features that are to be generated in a work stage, and budget details and the latest end time for a work stage. The release criteria (quality gates) can identify the results of a work stage as successful and can assess the fulfillment of a work stage. A reference for all work stages simulates the model based on a fictitious sample project, interference variables are introduced, the project implementation is simulated for each interference variable, respectively, the deviations from the reference run are automatically determined, respectively, for each interference variable, and an analysis of the influence of the release criteria (quality gates) regarding compliance with the budget and the schedule is performed based on the determined deviations from the reference run.
摘要翻译：在过程模型的计算机辅助优化的方法和系统中，定义的规范和相关的发布准则（质量门）可用于每个工作阶段。规格包括服务文件，将在工作阶段生成的结果功能，以及预算明细和工作阶段的最终结束时间。发布标准（质量门）可以将工作阶段的结果确定为成功，并可以评估工作阶段的实现情况。所有工作阶段的参考模拟基于虚拟样本项目的模型，引入干扰变量，分别对每个干扰变量模拟项目实施，对于每个干扰变量，分别自动确定与参考运行的偏差，并且基于所确定的参考运行偏差来执行关于符合预算和调度的发布标准（质量门）的影响的分析。

23. 发明申请

US20120222514A1 TOOTHED GEAR WHEEL WITH EXCHANGEABLE TOOTHING 审中-公开
标题翻译：带可交换牙齿的齿轮
公开(公告)号：US20120222514A1
公开(公告)日：2012-09-06
申请号：US13401936
申请日：2012-02-22
申请人： Thomas Ehben , Jan-Dirk Reimers
发明人： Thomas Ehben , Jan-Dirk Reimers
IPC分类号： F16H55/12
CPC分类号： F16H55/12 , F16H2055/175 , Y10T74/19893
摘要： A toothed gear wheel with toothed wheel body and exchangeable teeth is disclosed. One or more teeth are embodied as a component which is able to be detachably connected to the toothed wheel body of the toothed gear wheel. A transmission embodied with the toothed gear wheel is disclosed. A component with suitable for use in a toothed gear wheel with toothed wheel body is also disclosed.
摘要翻译：公开了一种带齿轮和可更换齿的齿轮。一个或多个齿被实施为能够可拆卸地连接到齿轮的齿轮的部件。公开了具有齿形齿轮的变速器。还公开了一种适用于带有齿轮的齿轮的部件。

24. 发明申请

US20100323360A1 Oligonucleotide arrangements, processes for their employment and their use 审中-公开
标题翻译：寡核苷酸安排，就业及其使用过程
公开(公告)号：US20100323360A1
公开(公告)日：2010-12-23
申请号：US12805878
申请日：2010-08-23
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
IPC分类号： C12Q1/68 , G01N33/50
CPC分类号： C12Q1/6876 , B82Y5/00 , B82Y10/00 , Y10T436/143333
摘要： Oligonucleotide arrangements are disclosed which, in each case, have at least two oligonucleotide sequences linked via at least one spacer. A process is disclosed using the oligonucleotide arrangements for the amplification and/or detection of nucleic acid sequences with formation of crosslinked conglomerates. The process can be used, for example, for the sensitive, simple and inexpensive detection of nucleic acid sequences.
摘要翻译：公开了寡核苷酸排列，其在每种情况下具有通过至少一个间隔物连接的至少两个寡核苷酸序列。公开了使用寡核苷酸排列来扩增和/或检测与形成交联聚集体的核酸序列的方法。该方法可用于例如核酸序列的灵敏，简单且廉价的检测。

25. 发明申请

US20090035746A1 Device and Method for Preparing a Sample for an Analysis and Device and Method for Analyzing a Sample 审中-公开
标题翻译：用于分析样品准备样品的装置和方法以及用于分析样品的方法
公开(公告)号：US20090035746A1
公开(公告)日：2009-02-05
申请号：US11922879
申请日：2006-06-21
申请人： Thomas Ehben , Christian Zilch
发明人： Thomas Ehben , Christian Zilch
IPC分类号： C12Q1/00 , C12M1/00 , C12N13/00 , C12P19/34
CPC分类号： B01L3/502761 , B01L7/52 , B01L2200/0647 , B01L2300/0816 , B01L2300/087 , B01L2300/1822 , B01L2400/043 , G01N35/0098
摘要： A device and method are disclosed for preparing a sample for an analysis and a device and method are disclosed for analyzing a sample. In at least one embodiment, a device is disclosed for preparing a sample for analysis including means for binding at lest one biological structure of the sample, means for releasing at least one biological molecule contained in the at least one structure, and means for binding the at least one released molecule. The means for binding the at least one structure and the means for binding the at least one molecule can move.
摘要翻译：公开了一种用于制备用于分析的样品的装置和方法，并且公开了用于分析样品的装置和方法。在至少一个实施方案中，公开了用于制备用于分析的样品的装置，包括用于结合样品的至少一个生物结构的装置，用于释放至少一个结构中包含的至少一个生物分子的装置，以及用于结合至少一个释放的分子。用于结合所述至少一种结构的方法和用于结合至少一种分子的方法可移动。

26. 发明申请

US20070148678A1 Device and method for carrying out a nucleic acid test, and method for producing such a device 审中-公开
标题翻译：用于进行核酸试验的装置和方法，以及用于制备这种装置的方法
公开(公告)号：US20070148678A1
公开(公告)日：2007-06-28
申请号：US11636454
申请日：2006-12-11
申请人： Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
发明人： Thomas Ehben , Hans-Dieter Feucht , Christian Zilch
IPC分类号： C12Q1/68 , C12M1/34
CPC分类号： C12Q1/6837 , B01L3/50851 , B01L7/52 , B01L2200/0642 , B01L2300/069 , B01L2400/0421 , C12Q1/686 , C12Q2565/537 , C12Q2565/501
摘要： A device and a method are disclosed for carrying out nucleic acid tests. The device includes a substrate and one or more gel pads arranged on the substrate and designed so that at least one of the biological and chemical reactions necessary for the test takes place in them, particularly a polymerase chain reaction. A method for producing such a device is also disclosed.
摘要翻译：公开了用于进行核酸测试的装置和方法。该装置包括衬底和布置在衬底上的一个或多个凝胶垫，并被设计成使得在其中进行测试所需的生物和化学反应中的至少一个，特别是聚合酶链式反应。还公开了一种用于制造这种装置的方法。

27. 发明授权

US06465868B1 Integrated circuit having capacitive elements 有权
标题翻译：具有电容元件的集成电路
公开(公告)号：US06465868B1
公开(公告)日：2002-10-15
申请号：US09640150
申请日：2000-08-16
申请人： Thomas Ehben , Thomas Steinecke , Jens Rosenbusch
发明人： Thomas Ehben , Thomas Steinecke , Jens Rosenbusch
IPC分类号： H01L27108
CPC分类号： H01L23/5223 , H01L23/5222 , H01L23/66 , H01L27/0805 , H01L2924/0002 , H01L2924/3011 , H01L2924/00
摘要： An integrated circuit having capacitive elements for smoothing a supply voltage is described. In this case, at least one additional metal electrode, which is configured as a high frequency-optimized capacitance and is distinguished by an extremely low sheet resistance, is connected in parallel with the MOS capacitances. By connecting the areally highly effective MOS capacitance, which, however, is connected with a somewhat higher impedance, in parallel with areally less effective metal capacitances, which, however, are connected to the supply voltage in a very low-impedance manner, it is possible to obtain broadband buffering and thus decoupling of high-frequency interference signals. Very high-frequency interference components are attenuated on the chip and do not pass into the system surrounding the integrated circuit.
摘要翻译：描述了具有用于平滑电源电压的电容元件的集成电路。在这种情况下，配置为高频优化电容并且被极低的薄层电阻区分的至少一个附加金属电极与MOS电容并联连接。然而，通过连接非常有效的MOS电容，该MOS电容与稍高阻抗连接，与以非常低阻抗的方式连接到电源电压的非常不太有效的金属电容并联。可能获得宽带缓冲，从而解耦高频干扰信号。非常高频的干扰元件在芯片上衰减，不会进入集成电路周围的系统。

28. 发明授权

US06433592B1 Method and apparatus for switching a field-effect transistor 有权
标题翻译：用于切换场效应晶体管的方法和装置
公开(公告)号：US06433592B1
公开(公告)日：2002-08-13
申请号：US09674823
申请日：2000-11-06
申请人： Thomas Ehben
发明人： Thomas Ehben
IPC分类号： H03B100
CPC分类号： H03K17/163
摘要： A method and apparatus in which the switching of a field-effect transistor is effected by the application of a control voltage suitable for switching to an RC element connected upstream of the gate terminal. The method and apparatus are distinguished by the fact that switching of the field-effect transistor is carried out using a control voltage that at least temporarily only slightly exceeds the threshold voltage via an attenuation circuit which has to be applied to the gate terminal of the field-effect transistor in order to be able to effect switching of the transistor.
摘要翻译：通过施加适于切换到连接在栅极端子上游的RC元件的控制电压来实现场效应晶体管的切换的方法和装置。该方法和装置的特征在于，使用至少暂时仅通过必须施加到场的栅极端的衰减电路略微超过阈值电压的控制电压来执行场效应晶体管的切换 - 为了能够实现晶体管的切换，晶体管的效果很好。

29. 发明申请

US20110078178A1 View Server and Method for Providing Specific Data of Objects and/or Object Types 审中-公开
标题翻译：查看服务器和提供对象和/或对象类型的特定数据的方法
公开(公告)号：US20110078178A1
公开(公告)日：2011-03-31
申请号：US12890924
申请日：2010-09-27
申请人： Thomas Ehben
发明人： Thomas Ehben
IPC分类号： G06F17/30
CPC分类号： G06F16/2445 , G06F16/907
摘要： A central data server provides data of objects and/or object types. The data are configured as metadata which characterise content available at a site arranged outside a memory of the data server. The data have a validity range and/or a solution space. The contents are uniform within the validity range and/or solution space and are valid for all participants. The data server supplies meta-information in response to a query.
摘要翻译：中央数据服务器提供对象和/或对象类型的数据。数据被配置为表示在布置在数据服务器的存储器外部的站点上可用的内容的元数据。数据具有有效范围和/或解空间。内容在有效范围和/或解决方案空间内是均匀的，对所有参与者都是有效的。数据服务器提供响应于查询的元信息。

30. 发明申请

US20100068823A1 Carrier Material, Method for the Production and Use Thereof 审中-公开
标题翻译：载体材料，其生产和使用方法
公开(公告)号：US20100068823A1
公开(公告)日：2010-03-18
申请号：US11922755
申请日：2006-06-21
申请人： Thomas Ehben
发明人： Thomas Ehben
IPC分类号： G01N33/545 , C08F116/06
CPC分类号： G01N33/54333 , G01N2446/20 , G01N2446/66
摘要： An embodiment of the present invention relates to a carrier material which is used in a method of diagnosis and which comprises a base material which is provided with a surface which is equipped with at least two different affinity ligands.
摘要翻译：本发明的一个实施方案涉及用于诊断方法的载体材料，其包含基材，该基材具有配备有至少两种不同亲和配体的表面。

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