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    • 21. 发明授权
    • Pneumatic bioreactor
    • 气动生物反应器
    • US07713730B2
    • 2010-05-11
    • US11739659
    • 2007-04-24
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • J. Gregory ZeikusKyungnam KimThomas A. PostKeith E. Johnson
    • C12M1/06
    • C12M27/06B01F3/04588B01F7/00308B01F7/00916B01F7/04B01F15/005B01F15/00545C12M27/20
    • A pneumatic bioreactor having a containment vessel which includes a semi-cylindrical concavity defined by the vessel bottom. A mixing apparatus includes a rotational mixer rotatably mounted within the containment vessel about a horizontal axis. The rotational mixer has buoyancy-driven mixing cavities which are fed by a gas supply beneath the rotational mixer. The mixing apparatus extends into the semi-cylindrical concavity to substantially fill that concavity. The rotational mixer is divided into two wheels with outer paddles extending axially outwardly and inner paddles extending axially inwardly on either side of each wheel. Blades between the outer and inner paddles form impellers in the wheels to induce axial flow through the wheels in opposite directions. Stationary baffles fixed relative to the containment vessel are inclined toward the rotational mixer in the direction of rotation. The containment vessel may be of film and supported by a structural housing also having a semi-cylindrical concavity defined by the housing bottom.
    • 一种具有容纳容器的气动生物反应器,其包括由容器底部限定的半圆柱形凹面。 混合装置包括旋转混合器,其围绕水平轴可旋转地安装在容纳容器内。 旋转混合器具有浮力驱动的混合腔,其通过旋转混合器下面的气体供给。 混合装置延伸到半圆柱形凹部中以基本上填充该凹部。 旋转混合器被分成两个轮子,其外侧叶片沿轴向向外延伸,内部桨叶在每个轮的任一侧上轴向向内延伸。 外桨叶和内桨叶之间的叶片在车轮中形成叶轮,以引起相反方向的轴向流动。 相对于安全壳固定的固定挡板在旋转方向上朝向旋转混合器倾斜。 安全壳可以是薄膜,并由具有由壳体底部限定的半圆柱形凹面的结构外壳支撑。
    • 22. 发明申请
    • Pneumatic Bioreactor
    • 气动生物反应器
    • US20080261299A1
    • 2008-10-23
    • US11739089
    • 2007-04-23
    • J. Gregory ZeikusKyungnam KimDavid S. Dickey
    • J. Gregory ZeikusKyungnam KimDavid S. Dickey
    • C12M1/02
    • C12M27/06
    • A pneumatic bioreactor having a containment vessel which includes a semi-cylindrical concavity defined by the vessel bottom. A mixing apparatus includes a rotational mixer rotatably mounted within the containment vessel about a horizontal axis. The rotational mixer has buoyancy-driven mixing cavities which are fed by a gas supply beneath the rotational mixer. The mixing apparatus extends into the semi-cylindrical concavity to substantially fill that concavity. The rotational mixer is divided into two wheels with outer paddles extending axially outwardly and inner paddles extending axially inwardly on either side of each ring. Blades between the outer and inner paddles form impellers in the wheels to induce axial flow through the rings in opposite directions. The containment vessel may be of film and supported by a structural housing also having a semi-cylindrical concavity defined by the housing bottom.
    • 一种具有容纳容器的气动生物反应器,其包括由容器底部限定的半圆柱形凹面。 混合装置包括旋转混合器,其围绕水平轴可旋转地安装在容纳容器内。 旋转混合器具有浮力驱动的混合腔,其通过旋转混合器下面的气体供给。 混合装置延伸到半圆柱形凹部中以基本上填充该凹部。 旋转混合器被分成两个轮,其外侧叶片沿轴向向外延伸,并且内部桨叶在每个环的任一侧上轴向向内延伸。 外桨叶和内桨叶之间的叶片在轮中形成叶轮以引起轴向流动通过环的相反方向。 安全壳可以是薄膜,并由具有由壳体底部限定的半圆柱形凹面的结构外壳支撑。
    • 23. 发明授权
    • Optimal multi-class classifier threshold-offset estimation with particle swarm optimization for visual object recognition
    • 用于视觉对象识别的粒子群优化的最优多类分类器阈值偏移估计
    • US08768868B1
    • 2014-07-01
    • US13440881
    • 2012-04-05
    • Shinko Y. ChengYang ChenDeepak KhoslaKyungnam Kim
    • Shinko Y. ChengYang ChenDeepak KhoslaKyungnam Kim
    • G06N5/00
    • G06N5/00
    • Described is a system for multi-class classifier threshold-offset estimation for visual object recognition. The system receives an input image with input features for classifying. A pair-wise classifier is trained for each pair of a plurality of object classes. A set of classification responses is generated, and a multi-class receiver-operating-characteristics (ROC) curve is computed for a set of threshold-offsets. An objective function of classification performance is computed from the ROC curve and optimized using particle swarm optimization (PSO) to generate a set of optimized threshold-offsets. The optimized threshold-offsets are then applied to the classification responses. The resulting classification responses are compared to a predetermined value to classify each input feature as belonging to one object class or another. The tuning of the threshold-offsets with (PSO) improves classification performance in a visual object recognition system.
    • 描述了用于视觉对象识别的多类分类器阈值偏移估计的系统。 系统接收具有输入特征进行分类的输入图像。 针对多对象类的每一对训练一对成对的分类器。 生成一组分类响应,并计算一组阈值偏移量的多类接收器操作特性(ROC)曲线。 从ROC曲线计算分类性能的目标函数,并使用粒子群优化(PSO)进行优化,以生成一组优化的阈值偏移。 然后将优化的阈值偏移应用于分类响应。 将所得分类响应与预定值进行比较,以将每个输入特征分类为属于一个对象类或另一对象类。 使用(PSO)调整阈值偏移可提高视觉对象识别系统中的分类性能。