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21. 发明授权

US5173126A Aluminum brazing paste 失效
标题翻译：铝烧烤膏
公开(公告)号：US5173126A
公开(公告)日：1992-12-22
申请号：US879308
申请日：1992-05-07
申请人： Toshiaki Ogura , Tadashi Takemoto , Tatsuyuki Ujie
发明人： Toshiaki Ogura , Tadashi Takemoto , Tatsuyuki Ujie
IPC分类号： B23K35/22 , B23K35/36 , B23K35/363 , B23K103/10
CPC分类号： B23K35/3613 , B23K35/36 , B23K35/3605
摘要： Discloses an aluminium brazing paste which not only has excellent preservability and coating performance but also reveals excellent brazing characteristics; said aluminium brazing paste according to this invention comprises, per 100 parts by weight of aluminum-containing metal powder with 10 to 500 .mu.m of mean particle size for aluminium brazing, of 0.5 to 15 parts by weight of flux and 30 to 80 parts by weight of a liquid polyisobutylene with 300 to 1500 of average molecular weight and/or its hydrogenated product.

22. 发明授权

US4618695A Method of preparing methyl ester and its hydrochloride 失效
标题翻译：制备甲酯及其盐酸盐的方法
公开(公告)号：US4618695A
公开(公告)日：1986-10-21
申请号：US611548
申请日：1984-05-17
申请人： Yoichi Ozawa , Shinichi Kishimoto , Emiko Shinohara , Tadashi Takemoto , Chikahiko Eguchi
发明人： Yoichi Ozawa , Shinichi Kishimoto , Emiko Shinohara , Tadashi Takemoto , Chikahiko Eguchi
IPC分类号： C07K5/075 , C07C101/02
CPC分类号： C07K5/0613
摘要： A method of preparing .alpha.-L-phenylalanine methyl ester and its hydrochloride, which comprises dissolving .alpha.-L-aspartyl-L-phenylalanine .beta.-methyl ester in a methanol/hydrochloric acid mixture solvent which contains, when hydrochloric acid is expressed in terms of concentrated hydrochloric acid and water, 0 to 20% by volume of methanol, 8 to 55% by volume of concentrated hydrochloric acid and water (balance) in a concentration from 0.01 mol/dl to 0.3 mol/dl; holding the solution at 0.degree. to 60.degree. C. to effect intramolecular ester exchange reaction and crystallize out the formed .alpha.-L-aspartyl-L-phenylalanine methyl ester as its hydrochloride; isolating the hydrochloride; and obtaining, when required, the free ester by neutralization with an alkali, is disclosed.
摘要翻译：一种制备α-L-苯丙氨酸甲酯及其盐酸盐的方法，其包括将α--L-天冬氨酰基-L-苯丙氨酸β-甲酯溶于甲醇/盐酸混合物溶剂中，所述溶剂含有当盐酸以浓盐酸和水，0至20体积％甲醇，8至55体积％浓盐酸和水（余量），浓度为0.01mol / dl至0.3mol / dl; 将溶液保持在0〜60℃，进行分子内酯交换反应，结晶形成的α-L-天冬氨酰-L-苯丙氨酸甲酯为盐酸盐; 分离盐酸盐; 并且当需要时通过用碱中和获得游离酯。

23. 发明授权

US07951835B2 Crystals of non-natural-type stereoisomer salt of monatin and use thereof 有权
标题翻译：莫纳甜的非天然型立体异构体盐的晶体及其用途
公开(公告)号：US07951835B2
公开(公告)日：2011-05-31
申请号：US12825886
申请日：2010-06-29
申请人： Yusuke Amino , Kazuko Yuzawa , Kenichi Mori , Tadashi Takemoto
发明人： Yusuke Amino , Kazuko Yuzawa , Kenichi Mori , Tadashi Takemoto
IPC分类号： A61K31/40 , C07D209/18
CPC分类号： C07D209/20 , A23L2/60 , A23L27/30 , A23L27/32
摘要： The present invention provides salt crystals of non-natural stereoisomer forms of monatin and to the use thereof.
摘要翻译：本发明提供了莫纳甜的非天然立体异构形式的盐晶体及其用途。

24. 发明申请

US20080199921A1 PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES 审中-公开
标题翻译：生产谷氨酸衍生物的方法
公开(公告)号：US20080199921A1
公开(公告)日：2008-08-21
申请号：US12108889
申请日：2008-04-24
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
IPC分类号： C12P17/10
CPC分类号： C12P17/10 , C12N9/88 , C12P7/50 , C12P13/04 , C12P13/14
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译：本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法催化其转化。

25. 发明申请

US20070072277A1 PROCESS FOR PRODUCING GLUTAMATE DERIVATIVES 失效
标题翻译：生产谷氨酸衍生物的方法
公开(公告)号：US20070072277A1
公开(公告)日：2007-03-29
申请号：US11561665
申请日：2006-11-20
申请人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
发明人： Masakazu Sugiyama , Kunihiko Watanabe , Nao Funakoshi , Yusuke Amino , Shigeru Kawahara , Tadashi Takemoto
IPC分类号： C12P7/50 , C12N1/21
CPC分类号： C12P17/10 , C12N9/88 , C12P7/50 , C12P13/04 , C12P13/14
摘要： The present invention relates to a process for producing efficiently glutamic acid derivatives (including salts thereof) such as monatin by converting a substituted α-keto acid of formula (1) into a glutamic acid derivative of formula (2) in the presence of an enzyme catalyzing conversion of the same.
摘要翻译：本发明涉及通过在式（2）的存在下将式（1）的取代的α-酮酸转化为式（2）的谷氨酸衍生物而有效地生产谷氨酸衍生物（包括其盐）的莫纳甜的方法催化其转化。

26. 发明授权

US06963526B2 Disc recording apparatus, disc recording method, and disc recording control program 失效
标题翻译：光盘记录装置，光盘记录方法和光盘记录控制程序
公开(公告)号：US06963526B2
公开(公告)日：2005-11-08
申请号：US10304326
申请日：2002-11-26
申请人： Tadashi Takemoto , Hisanori Itoga
发明人： Tadashi Takemoto , Hisanori Itoga
IPC分类号： G11B20/10 , G11B7/00 , G11B7/0045 , G11B7/007 , G11B20/12 , G11B27/00 , G11B27/034 , G11B27/32
CPC分类号： G11B27/034 , G11B7/0045 , G11B7/007 , G11B20/1217 , G11B27/322 , G11B2220/218 , G11B2220/2545
摘要： When data in a volume in the excess of a specification of a disc is recorded on an optical disc (D) (overburn recording), overburn area information indicating a position to terminate data recording is set in a volatile memory (333) of an optical disc recording apparatus (300). The optical disc recording apparatus records the data in an overburn area of the optical disc by referring to the overburn area information set in the volatile memory and terminate the recording of the data when the recording position in the current point in time agrees with the position to terminate recording indicated by the overburn area information that is set in a second storage area (333b).
摘要翻译：当超过光盘规格的卷中的数据被记录在光盘（D）（过度记录）上时，指示终止数据记录的位置的超燃区域信息被设置在光学盘记录装置（300）。光盘记录装置通过参照在易失性存储器中设定的超燃烧区域信息将数据记录在光盘的超燃烧区域，并且当当前时间点的记录位置与位置对应时，终止数据的记录终止由设置在第二存储区域（333b）中的超燃烧区域信息所指示的记录。

27. 发明申请

US20050202542A1 Production method of D-alloisoleucine 审中-公开
标题翻译： D-异亮氨酸的生产方法
公开(公告)号：US20050202542A1
公开(公告)日：2005-09-15
申请号：US10855349
申请日：2004-05-28
申请人： Shogo Maruyama , Ikuo Kira , Tadashi Takemoto
发明人： Shogo Maruyama , Ikuo Kira , Tadashi Takemoto
IPC分类号： C12P13/04
CPC分类号： C12P13/06
摘要： The present invention provides a production method of D-alloisoleucine, a protected compound thereof or a salt thereof, which is industrially useful, and which efficiently produces D-alloisoleucine having a high purity, a protected compound thereof and a salt thereof, and more particularly, a method including steps (a) to (c): (a) carbamoylating L-isoleucine to give L-(N-carbamoyl)isoleucine, (b) conducting intramolecular dehydration condensation of L-(N-carbamoyl)isoleucine to give L-5-sec-butylhydantoin, and (c) conducting an enzyme reaction of L-5-sec-butylhydantoin with hydantoin racemase (HRase), D-hydantoinase (D-HHase) and N-carbamoyl-D-amino acid hydrolase (D-CHase) to give D-alloisoleucine.
摘要翻译：本发明提供了在工业上有用的D-异亮氨酸，其保护的化合物或其盐的生产方法，并且其有效地生产具有高纯度的D-异亮氨酸，其保护的化合物及其盐，更特别地，（a）〜（c）的方法：（a）氨基甲酰化L-异亮氨酸得到L-（N-氨基甲酰基）异亮氨酸，（b）进行L-（N-氨基甲酰基）异亮氨酸的分子内脱水缩合，得到L 5-仲丁基乙内酰脲，（c）进行L-5-仲丁基乙内酰脲与乙内酰脲消旋酶（HRase），D-乙内酰脲酶（D-HHase）和N-氨基甲酰基-D-氨基酸水解酶 -CHase），得到D-异亮氨酸。

28. 发明申请

US20050107473A1 Process for producing tert-leucine 审中-公开
标题翻译：制备叔亮氨酸的方法
公开(公告)号：US20050107473A1
公开(公告)日：2005-05-19
申请号：US10934547
申请日：2004-09-07
申请人： Kazutaka Nagashima , Tadashi Takemoto
发明人： Kazutaka Nagashima , Tadashi Takemoto
IPC分类号： C07C227/42 , C07C229/08 , A61K31/198 , C07C227/34
CPC分类号： C07C227/42 , C07C229/08
摘要： The present invention provides a method of producing tert-leucine, which includes reacting tert-leucine with substituted benzenesulfonic acid represented by the following formula (1) wherein R1 and R2 are each independently a hydrogen atom, an alkyl group or a halogen atom, except a compound wherein R1 and R2 are both hydrogen atoms, in a solvent, to give tert-leucine.substituted benzenesulfonate represented by the following formula (2) wherein R1 and R2 are the same substituents as above, separating the salt by crystallization and then dissociating the salt. According to the present invention, a production method of tert-leucine is provided, which includes forming a tert-leucine salt hardly soluble in a solvent and crystallization thereof to efficiently recover tert-leucine from the solvent.
摘要翻译：本发明提供了一种生产叔亮氨酸的方法，其包括使叔 - 亮氨酸与下式（1）表示的取代苯磺酸反应，其中R 1和R 2各自独立地为氢原子，烷基或卤素原子，除化合物，其中R1和R2都是氢原子，在溶剂中，得到由下式（2）表示的叔 - 亮氨酸取代的苯磺酸盐，其中R 1和R 2是与上述相同的取代基，通过结晶分离盐，然后解离盐。根据本发明，提供了一种叔 - 亮氨酸的制备方法，其包括形成难溶于溶剂的叔 - 亮氨酸盐和结晶，以有效地从溶剂中回收叔 - 亮氨酸。

29. 发明授权

US06706304B1 Granular sweetener 失效
标题翻译：颗粒甜味剂
公开(公告)号：US06706304B1
公开(公告)日：2004-03-16
申请号：US09581180
申请日：2000-07-14
申请人： Hirotoshi Ishida , Takeshi Nagai , Tadashi Takemoto , Yuichi Suzuki
发明人： Hirotoshi Ishida , Takeshi Nagai , Tadashi Takemoto , Yuichi Suzuki
IPC分类号： A23L1236
CPC分类号： A23L27/32
摘要： Herein is disclosed a granulated sweetener comprising Aspartame and Acesulfame-K as active ingredients, wherein the amount of the Acesulfame-K is 5 to 90% by weight based on the total amount of both the components and wherein the maximum particle size of the granules is about 1,400 &mgr;m or less, in which granulated sweetener the poorly dissoluble, high intense synthetic sweetener Aspartame (APM) is improved in solubility.
摘要翻译：本文公开了包含天冬甜素和乙酰磺胺酸K作为活性成分的颗粒状甜味剂，其中基于两种成分的总量，所述乙酰磺胺酸钾的量为5-90重量％，并且其中所述颗粒的最大粒径为约1400毫克或更少，其中颗粒状甜味剂不易溶解，高强度合成甜味剂天冬甜精（APM）的溶解度提高。

30. 发明授权

US06630191B1 Aspartyl dipeptide ester derivatives and sweeteners 有权
标题翻译：天冬氨酰二肽酯衍生物和甜味剂
公开(公告)号：US06630191B1
公开(公告)日：2003-10-07
申请号：US09736149
申请日：2000-12-15
申请人： Yusuke Amino , Kazuko Yuzawa , Tadashi Takemoto , Ryoichiro Nakamura
发明人： Yusuke Amino , Kazuko Yuzawa , Tadashi Takemoto , Ryoichiro Nakamura
IPC分类号： A23L1236
CPC分类号： C07K5/06113 , A23L5/44 , A23L27/32
摘要： The present invention relates to novel, aspartyl dipeptide ester derivatives and salts thereof, such as N-[N-(3-(3-hydroxy-4-methoxyphenyl)propyl]-L-&agr;-aspartyl]-L-(&agr;-methyl)phenylalanine 1-methyl ester which provide high degrees of sweetness in comparison to conventional products, compositions and products containing the novel aspartyl dipeptide ester derivatives and method of producing the novel aspartyl dipeptide ester derivatives.
摘要翻译：本发明涉及新型天冬氨酰二肽酯衍生物及其盐，例如N- [N-（3-（3-羟基-4-甲氧基苯基）丙基] -L-α-天冬氨酰基] -L-（α-甲基）苯丙氨酸1-甲酯，其与常规产品，含有新型天冬氨酰二肽酯衍生物的组合物和产品以及生产新型天冬氨酰二肽酯衍生物的方法相比，具有高度的甜度。

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