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    • 24. 发明公开
    • METHOD AND APPARATUS FOR CONTROLLING A DECODING OF INFORMATION ENCODED IN SYNTHESIZED OLIGOS
    • 方法和设备,用于控制编码信息合成的寡核苷酸的解码
    • EP3146458A1
    • 2017-03-29
    • EP15720347.2
    • 2015-05-11
    • Thomson Licensing
    • HUETTER, IngoGAEDKE, KlausCHEN, XiaomingBLAWAT, Meinolf
    • G06F19/22
    • G06F19/22G06N3/123
    • A method for controlling a decoding of information encoded in a plurality of synthesized oligos, encoded using an error detection code identified by an associated identifier, and an apparatus configured to perform the method are described. A sequenced oligo of the synthesized oligos is fetched (11). The identifier associated with the sequenced oligo is read (12). The error detection code of the information encoded in the sequenced oligo is evaluated (13). Information encoded in the oligo is stored (14), if for a first time for an oligo having associated a read identifier the evaluated error detection code indicates no error. The processing is repeated (15) for subsequent oligos until, for at least a defined set of different identifiers of an expected set, information encoded in corresponding sequenced oligos for which the evaluated error detection code indicates no error have been stored.
    • 编码的使用一种用于控制在合成寡核苷酸的多个编码信息的解码,在方法的错误检测码所识别的相关联的BY标识符,以及向设备被配置为执行所描述的方法。 合成的寡核苷酸的寡核苷酸测序被取出(11)。 与测序寡相关联的标识符被读取(12)。 在测序的寡核苷酸所编码的信息的错误检测码进行评估(13)。 在寡核苷酸编码的信息被存储(14)中,如果在第一时间对寡具有相关联的读取识别符的评估的错误检测码指示没有错误。 该处理被重复(15),用于随后的寡聚物,直到在至少为一组定义的一组预期的不同的标识符,在测序CORRESPONDING寡核苷酸的量,评估的错误检测码指示没有差错编码信息的已经被存储。
    • 27. 发明公开
    • METHOD AND APPARATUS FOR ENCODING INFORMATION UNITS IN CODE WORD SEQUENCES AVOIDING REVERSE COMPLEMENTARITY
    • 信息编码单元编码字序列避免的方法和设备UMKEHRKOMPLEMENTARITÄT
    • EP3158647A1
    • 2017-04-26
    • EP15729129.5
    • 2015-06-09
    • Thomson Licensing
    • HUETTER, IngoGAEDKE, KlausCHEN, Xiao-MingBLAWAT, Meinolf
    • H03M5/14
    • H03M7/46G06N3/123H03M5/145
    • A method (100) and an apparatus (200) for encoding information in code word sequences are described which avoid reverse complementarity of the sequences, making them suitable for synthesizing nucleic acid strands. Multiple codes are provided (102), consisting of a same amount of corresponding code words. No word belongs to more than one code. Each code could completely encode all information units which are encoded using code word sequences generated from the codes. Generating (105) a sequence comprises: selecting (106), from code words of a code, a next code word to be appended to the sequence; appending (108) the next code word if a concatenation of the sequence and the next code word does not contain a reverse complementary of any code symbol sequence that at least partly contains the next code word; and otherwise (109) selecting a corresponding next code word from a different code and repeating the appending.
    • 一种用于编码的码字中的序列的信息的方法(100)和设备(200)中描述了避免的序列的反向互补,使得它们适用于合成的核酸链。 提供了多个码(102)由相同量CORRESPONDING码字中的。 无字属于一个以上的代码。 每个代码可完全呼叫编码哪些是使用从码生成代码字的序列编码的所有信息单元。 产生(105)的序列包括:选择(106),从一个代码,下一个代码字被附加到序列的码字; 追加(108),如果序列与下一个代码字的级联不包含任何代码符号序列的反向互补的下一个码字没有至少部分地包含下一个代码字; 否则(109)从不同的代码选择相应的下一个代码字,并且重复该追加。