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21. 发明授权

US5925640A Apoptosis regulating composition 失效
标题翻译：凋亡调节组成
公开(公告)号：US5925640A
公开(公告)日：1999-07-20
申请号：US853745
申请日：1997-05-09
申请人： Satoru Nakai , Koutoku Aihara , Hitomi Mori , Michiaki Tominaga , Masakazu Adachi , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito
发明人： Satoru Nakai , Koutoku Aihara , Hitomi Mori , Michiaki Tominaga , Masakazu Adachi , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito
IPC分类号： A61K31/495 , A61K31/496
CPC分类号： A61K31/496 , A61K31/495
摘要： An object of the invention is to provide an apoptosis regulating composition. According to the invention, an apoptosis regulating composition is provided which comprises, as an active ingredient, at least one carbostyril derivatives of general formula (1) and salts thereof.
摘要翻译：本发明的目的是提供凋亡调节组合物。根据本发明，提供了一种凋亡调节组合物，其包含至少一种通式（1）的喹诺酮衍生物及其盐作为活性成分。

22. 发明授权

US5750529A Apoptosis regulating compostion 失效
标题翻译：凋亡调节组成
公开(公告)号：US5750529A
公开(公告)日：1998-05-12
申请号：US469505
申请日：1995-06-06
申请人： Satoru Nakai , Koutoku Aihara , Hitomi Mori , Michiaki Tominaga , Masakazu Adachi , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito
发明人： Satoru Nakai , Koutoku Aihara , Hitomi Mori , Michiaki Tominaga , Masakazu Adachi , Hiroyuki Ichikawa , Seiji Akamatsu , Fumio Saito
IPC分类号： A61K31/495 , A61K31/496 , A61K31/50
CPC分类号： A61K31/495 , A61K31/496
摘要： An object of the invention is to provide an apoptosis regulating composition. According to the invention, an apoptosis regulating composition is provided which comprises, as an active ingredient, at least one carbostyril derivatives of general formula (1) ##STR1## and salts thereof.
摘要翻译：本发明的目的是提供凋亡调节组合物。根据本发明，提供了一种凋亡调节组合物，其包含至少一种通式（1）的喹诺酮衍生物及其盐作为活性成分。

23. 发明授权

US5132413A Sugar chain 失效
标题翻译：糖链
公开(公告)号：US5132413A
公开(公告)日：1992-07-21
申请号：US588060
申请日：1990-09-25
申请人： Akihiro Aizawa , Nobuo Shimoda , Masakazu Adachi , Katsunari Tezuka , Hideko Ishihara , Hiroyuki Hanzawa , Yoji Arata , Noriko Takahashi
发明人： Akihiro Aizawa , Nobuo Shimoda , Masakazu Adachi , Katsunari Tezuka , Hideko Ishihara , Hiroyuki Hanzawa , Yoji Arata , Noriko Takahashi
IPC分类号： G01N33/50 , A61K31/715 , A61K39/00 , A61P29/00 , A61P35/00 , A61P43/00 , C07H3/06 , C08B37/00 , C12N5/06 , G01N33/574
CPC分类号： C07H3/06
摘要： A sugar chain of the following formula is disclosed. ##STR1## It can be prepared by separating glycoproteins from cell membrane components by using lectins which recognize the sugar chain, releasing the sugar chain structure from the glycoproteins, and purifying the released sugar chain. The sugar chain is useful for the diagnosis and treatment of cancer.
摘要翻译：公开了下式的糖链。通过使用识别糖链的凝集素，从糖蛋白释放糖链结构和纯化释放的糖链，可以通过从细胞膜组分中分离糖蛋白来制备。糖链可用于诊断和治疗癌症。

24. 发明授权

US4571382A Process for determining tumor-associated glycolinkage and method for diagnosis of cancer 失效
标题翻译：用于确定肿瘤相关的羟化蛋白沉淀的方法和用于诊断癌症的方法
公开(公告)号：US4571382A
公开(公告)日：1986-02-18
申请号：US288445
申请日：1981-07-30
申请人： Masakazu Adachi
发明人： Masakazu Adachi
IPC分类号： G01N33/574 , A61K35/38 , G01N33/58 , G01N33/66
CPC分类号： G01N33/58 , Y10S436/813 , Y10S436/827
摘要： Determination of tumor-associated glycolinkage (TAG) by:(1) competitively reacting body fluid TAG to be measured and a definite quantity of insolubilized TAG or TAG-like material with a definite quantity of lectin labelled with a labelling agent, separating the insolubilized TAG or insolubilized TAG-like material bound to the labelled lectin and unbound labelled lectin from each other, and measuring the labelling agent activity of either of them;(2) competitively reacting the material to be measured and a definite quantity of TAG or TAG-like material labelled with a labelling agent with a definite quantity of lectin or insolubilized lectin, separating the labelled TAG or labelled TAG-like material bound to lectin or insolubilized lectin and unbound labelled TAG or TAG-like material from each other, and measuring the labelling agent activity of either or them; or(3) reacting the material to be measured with the insolubilized lectin to form a TAG-insolubilized lectin complex, reacting this complex with a definite quantity of the labelled lectin, separating the complex bound to the labelled lectin and unbound labelled lectin from each other, and measuring the labelling agent activity of either of them.
摘要翻译：通过以下方法测定肿瘤相关的聚乙二醇化（TAG）：（1）将待测量的体液TAG与确定量的凝胶素与标记试剂标记的一定量的不溶TAG或TAG样物质进行竞争性反应，分离不溶TAG 或与标记的凝集素结合的不溶TAG样物质和未结合的标记的凝集素，并测量其中任一种的标记试剂活性; （2）使待测物质与确定量的凝胶素或不溶性凝集素标记的标签试剂TAG或TAG样材料竞争性地反应，分离与凝集素结合的标记的TAG或标记的TAG样物质，不溶性凝集素和未结合的标记TAG或TAG样物质，并测定其中任一种或它们的标记试剂活性; 或者（3）将待测量的物质与不溶性凝集素反应以形成TAG不溶性凝集素复合物，使该配合物与一定量的标记的凝集素反应，将与标记的凝集素结合的复合物和未结合的标记凝集素相互分离，并测量其中任一者的标记试剂活性。

25. 发明授权

US4455380A Process for determining tumor-associated glycolinkage 失效
标题翻译：确定肿瘤相关的乙二醇化的方法
公开(公告)号：US4455380A
公开(公告)日：1984-06-19
申请号：US344151
申请日：1982-01-29
申请人： Masakazu Adachi
发明人： Masakazu Adachi
IPC分类号： G01N33/574 , G01N33/58 , G01N33/56 , G01N33/60 , G01N33/68
CPC分类号： G01N33/57469 , G01N33/58 , Y10S436/808 , Y10S436/813 , Y10T436/143333
摘要： A process for determining the level of TAG in a sample of body fluid which comprises reacting the TAG in a sample of body fluid with an AG-binding lectin or L-fucose-binding lectin to form a TAG-lectin complex and measuring the amount of the TAG-lectin complex or an unreacted lectin is disclosed. The process shows low cross-reactivity with hepatic diseases and is useful for diagnosis of cancers.
摘要翻译：一种用于确定体液样品中TAG水平的方法，其包括使体液样品中的TAG与AG结合凝集素或L-岩藻糖结合凝集素反应以形成TAG-凝集素复合物并测量 TAG凝集素复合物或未反应的凝集素被公开。该过程显示与肝脏疾病的交叉反应性低，可用于诊断癌症。

26. 发明授权

US07677382B2 Method and apparatus for assembling and manufacturing 有权
标题翻译：装配和制造方法和装置
公开(公告)号：US07677382B2
公开(公告)日：2010-03-16
申请号：US11817600
申请日：2006-03-02
申请人： Sumio Noguchi , Masakazu Adachi
发明人： Sumio Noguchi , Masakazu Adachi
IPC分类号： B65G37/00
CPC分类号： B23P21/008 , B23P21/00 , B23P2700/50 , B25J9/0093
摘要： An assembling apparatus and method easily applicable to an existing production line and capable of improving assembling quality and reducing equipment cost. The assembling apparatus performs processing such as part assembling or the like to a processed part which is free-flow conveyed by a processed part conveyor. The processing is performed by a robot which is conveyed in the same direction as the processed part by a robot conveyor having its own motor. The processed part conveyor is provided with a removable pallet for supporting the processed part. The robot conveyor comprises a turntable which mounts and rotationally positions the robot thereon, a pallet support provided on the turntable so that the removed pallet from the processed part conveyor is supported thereon, and a connector for connecting with the processed part conveyor to synchronously convey the same.
摘要翻译：一种易于适用于现有生产线并能提高装配质量并降低设备成本的组装设备和方法。组装装置对由加工部输送机输送的自由流动的加工部进行部件组装等的处理。该处理由具有自己的马达的机器人输送机以与处理部相同的方向输送的机器人进行。经处理的部件输送机设置有用于支撑处理部件的可拆卸托盘。机器人输送机包括一个将机器人安装并旋转地定位在其上的转台，设置在转台上的托盘支架，使得从处理的部件输送机上卸下的托盘被支撑在其上，连接器用于与加工的部件输送机连接以同步地传送相同。

27. 发明申请

US20080302636A1 Method and Apparatus for Assembling and Manufacturing 有权
标题翻译：组装和制造的方法和装置
公开(公告)号：US20080302636A1
公开(公告)日：2008-12-11
申请号：US11817600
申请日：2006-03-02
申请人： Sumio Noguchi , Masakazu Adachi
发明人： Sumio Noguchi , Masakazu Adachi
IPC分类号： B65G47/24 , B65G47/00
CPC分类号： B23P21/008 , B23P21/00 , B23P2700/50 , B25J9/0093
摘要： An assembling apparatus and method easily applicable to an existing production line and capable of improving assembling quality and reducing equipment cost. The assembling apparatus performs processing such as part assembling or the like to a processed part which is free-flow conveyed by a processed part conveyor. The processing is performed by a robot which is conveyed in the same direction as the processed part by a robot conveyor having its own motor. The processed part conveyor is provided with a removable pallet for supporting the processed part. The robot conveyor comprises a turntable which mounts and rotationally positions the robots thereon, a pallet support provided on the turntable so that the removed pallet from the processed part conveyor is supported thereon, and a connector for connecting with the processed part conveyor to synchronously convey the same.
摘要翻译：一种易于适用于现有生产线并能提高装配质量并降低设备成本的组装设备和方法。组装装置对由加工部输送机输送的自由流动的加工部进行部件组装等的处理。该处理由具有自己的马达的机器人输送机以与处理部相同的方向输送的机器人进行。经处理的部件输送机设置有用于支撑处理部件的可拆卸托盘。机器人输送机包括一个转盘，其上安装和旋转地定位机器人，设置在转盘上的托盘支架，使得从处理的部件输送机上卸下的托盘被支撑在其上，连接器用于与加工的部件输送机连接以同步地传送相同。

28. 发明申请

US20080023295A1 CONVEYING OPERATION METHOD AND CONVEYING OPERATION DEVICE 有权
标题翻译：输送操作方法和输送操作装置
公开(公告)号：US20080023295A1
公开(公告)日：2008-01-31
申请号：US11782276
申请日：2007-07-24
申请人： Sumio Noguchi , Hideya Yamamuro , Mitsugu Takahashi , Masakazu Adachi
发明人： Sumio Noguchi , Hideya Yamamuro , Mitsugu Takahashi , Masakazu Adachi
IPC分类号： B65G47/29
CPC分类号： B25J9/0093 , B23P21/004 , B23P21/008 , B23P2700/50 , B23Q7/007 , G05B2219/39102
摘要： A conveying operation method and device that can continue an operation on a workpiece to prevent reduction in production efficiency in conveying a workpiece and performing a an operation on the workpiece even if conveyance of the workpiece is stopped during the operation on the workpiece. The workpiece is conveyed by a workpiece conveying device, a movable stand is moved in synchronization with the workpiece conveying device in operation areas along a conveying path, and an operation is performed on the workpiece by an operation device provided on the movable stand. When movement of the workpiece conveying device is stopped, the movable stand stops in synchronization with the workpiece conveying device to continue the operation on the workpiece and complete one cycle operation. When non-normal operation is performed on the workpiece, the workpiece is retracted to a position different from the conveying path while being supported by the movable stand.
摘要翻译：一种输送操作方法和装置，其可以在对工件的操作期间停止对工件的输送停止时，继续对工件进行操作，以防止工件输送时的生产效率降低并对工件进行操作。通过工件输送装置输送工件，沿着输送路径在工作区域中与工件输送装置同步地移动可动支架，通过设置在可动支架上的操作装置对工件进行动作。当工件输送装置的移动停止时，可动支架与工件输送装置同步地停止，以继续对工件进行操作并完成一个循环操作。当对工件进行非正常操作时，工件在被可动支架支撑的同时被缩回到与输送路径不同的位置。

29. 发明授权

US07241861B2 High density lipoprotein-reactive peptides 有权
标题翻译：高密度脂蛋白反应肽
公开(公告)号：US07241861B2
公开(公告)日：2007-07-10
申请号：US10476872
申请日：2002-05-15
申请人： Manabu Niimi , Kazushi Kanatani , Masakazu Adachi
发明人： Manabu Niimi , Kazushi Kanatani , Masakazu Adachi
IPC分类号： C07K14/775 , C07K14/47 , A61K38/17
CPC分类号： C07K14/775 , A61K38/00 , C07K14/47 , C07K14/705
摘要： A high-density lipoprotein-reactive peptide or a foam cell-reactive peptide as set forth in the following (a) or (b): (a) a peptide comprising the amino acid sequence represented by SEQ ID NO: 1; and (b) a peptide comprising an amino acid sequence derived from the amino acid sequence as specified in the above (a) by substitution, deletion, addition, or insertion of one or more amino acid residues and being capable of specifically binding to high-density lipoprotein cholesterol or withdrawing cholesterol from foam cells. Thus, peptides having novel amino acid sequences and being capable of specifically binding to HDL cholesterol or withdrawing cholesterol from foam cells are provided. These peptides are useful as drugs for various diseases caused by arteriosclerosis, lipid metabolic errors, and peripheral cholesterosis.
摘要翻译：如下（a）或（b）所示的高密度脂蛋白反应性肽或泡沫细胞反应性肽：（a）包含SEQ ID NO：1所示的氨基酸序列的肽; 和（b）通过取代，缺失，添加或插入一个或多个氨基酸残基并且能够特异性结合于上述（a）中的氨基酸序列的氨基酸序列，密度脂蛋白胆固醇或从泡沫细胞中提取胆固醇。因此，提供了具有新氨基酸序列并且能够特异性结合HDL胆固醇或从泡沫细胞中提取胆固醇的肽。这些肽可用作由动脉硬化，脂质代谢异常和外周胆固醇过多引起的各种疾病的药物。

30. 发明申请

US20070103252A1 Radio-frequency switching circuit and semiconductor device 失效
标题翻译：射频切换电路和半导体器件
公开(公告)号：US20070103252A1
公开(公告)日：2007-05-10
申请号：US11591462
申请日：2006-11-02
申请人： Tadayoshi Nakatsuka , Atsushi Suwa , Motoo Nakagawa , Masakazu Adachi
发明人： Tadayoshi Nakatsuka , Atsushi Suwa , Motoo Nakagawa , Masakazu Adachi
IPC分类号： H01P1/15
CPC分类号： H01P1/15 , H03K17/002 , H03K17/063 , H03K17/102 , H03K17/693
摘要： A common terminal 500 is connected to drains of FETs 101 and 102 via a capacitor 400. FETs 111 to 114 are serially connected, and inserted between a source of the FET 101 and a terminal 501 via a capacitor 401. Similarly, each of: FETs 121 to 124; FETs 131 to 133; FETs 141 to 143; FETs 151 to 153; and FETs 161 to 163 is inserted between the source of the FET 101 or an FET 102 and a corresponding one of terminals 502 to 506. This configuration allows a stray capacitance value of a transmission/reception path to be reduced at the time of transmission/reception, thereby obtaining a favorable radio-frequency characteristic.
摘要翻译：公共端子500经由电容器400连接到FET 101和102的漏极.FET 111至114串联连接，并且经由电容器401插入FET 101的源极和端子501之间。类似地，每个FET 121至124; FET 131〜133; FET 141〜143; FET 151〜153; 并且FET161〜163插入在FET101的源极或FET102与端子502〜506中的对应的一个之间。这种结构允许发送/接收路径的杂散电容值减小，接收，从而获得有利的射频特性。

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