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21. 发明申请

US20060142750A1 Devices and methods for treatment of skin conditions 有权
标题翻译：用于治疗皮肤病症的装置和方法
公开(公告)号：US20060142750A1
公开(公告)日：2006-06-29
申请号：US11299284
申请日：2005-12-09
申请人： Luiz Da Silva , George Choi
发明人： Luiz Da Silva , George Choi
IPC分类号： A61B18/04
CPC分类号： A61B18/082 , A61B2017/00734 , A61B2017/00761 , A61B2018/00005 , A61B2018/0047 , A61B2018/00714 , A61B2018/00761 , A61B2018/00791
摘要： Devices and methods for the treatment of skin conditions and lesions are disclosed herein. One aspect of the invention is a compact hand held device that can be safely used by those suffering from skin conditions, such as acne, warts, cold blisters, blemished skin, or fine wrinkles. The devices described herein employ the application of heat for the treatment of skin conditions and lesions. Typically, the peak temperatures employed are about 70° C. to about 400° C. by the devices, are achieved in less than about 1 second, and maintained for less than about 1 second. In some embodiments, the skin surface is heated with heat pulses. Thermal conduction transfers heat from the device to the skin and causes a biological response that accelerates acne clearing, treats blemished skin, itching, or fine wrinkles. The total heat transferred is low enough to prevent burns.
摘要翻译：本文公开了用于治疗皮肤病况和损伤的装置和方法。本发明的一个方面是紧凑的手持装置，其可以被患有皮肤状况的人安全地使用，例如痤疮，疣，冷水泡，瑕疵的皮肤或细皱纹。本文描述的装置使用热量来治疗皮肤病症和损伤。通常，所用装置的峰值温度为约70℃至约400℃，在小于约1秒钟内实现，并保持少于约1秒。在一些实施方案中，用热脉冲加热皮肤表面。热传导将热量从设备传递到皮肤，并引起加速痤疮清除，治疗瑕疵皮肤，瘙痒或细皱纹的生物反应。传热的总热量足够低以防止灼伤。

22. 发明申请

US20060129214A1 Skin treatment device 有权
公开(公告)号：US20060129214A1
公开(公告)日：2006-06-15
申请号：US11216595
申请日：2005-08-30
申请人： Luiz Da Silva , George Choi
发明人： Luiz Da Silva , George Choi
IPC分类号： A61F7/00
CPC分类号： A61B18/082 , A61B2017/00734 , A61B2017/00761
摘要： A compact hand held device is provided that can be safely used by those suffering from acne, blemished skin or fine wrinkles. The hand held device includes an on/off switch and a button that pulses the device when it is placed on the target site. A battery within the device powers a circuit board and drives a short pulse of current through a heating element, which heats up to approximately 300° C. in less than 0.1 sec. Thermal conduction transfers the heat to the skin and causes a biological response that accelerates acne clearing, treats blemished skin or fine wrinkles. The total heat transferred is low enough to prevent burns. Application of acne treatment creams and gels further accelerates treatment

23. 发明授权

US6059815A Microfabricated therapeutic actuators and release mechanisms therefor 失效
标题翻译：微型治疗执行器及其释放机制
公开(公告)号：US6059815A
公开(公告)日：2000-05-09
申请号：US67824
申请日：1998-04-28
申请人： Abraham P. Lee , Joseph P. Fitch , Daniel L. Schumann , Luiz Da Silva , William J. Benett , Peter A. Krulevitch
发明人： Abraham P. Lee , Joseph P. Fitch , Daniel L. Schumann , Luiz Da Silva , William J. Benett , Peter A. Krulevitch
IPC分类号： A61B17/00 , A61B17/12 , A61M25/16 , A61B17/28
CPC分类号： A61B17/1214 , A61B17/12022 , A61B2017/00867 , A61B2017/00871 , A61B2017/12068 , A61B2017/12077
摘要： Microfabricated therapeutic actuators are fabricated using a shape memory polymer (SMP), a polyurethane-based material that undergoes a phase transformation at a specified temperature (Tg). At a temperature above temperature Tg material is soft and can be easily reshaped into another configuration. As the temperature is lowered below temperature Tg the new shape is fixed and locked in as long as the material stays below temperature Tg. Upon reheating the material to a temperature above Tg, the material will return to its original shape. By the use of such SMP material, SMP microtubing can be used as a retaining/release actuator for the delivery of material, such as embolic coils, for example, through catheters into aneurysms, for example. The microtubing can be manufactured in various sizes and the phase change temperature Tg is determinate for an intended temperature target and intended use. The SMP microtubing can be positioned around or within an end of a deposit material. Various heating arrangements can be utilized with the SMP release mechanism, and the SMP microtubing can include a metallic coating for enhanced light absorption.
摘要翻译：使用形状记忆聚合物（SMP），在特定温度（Tg）下经历相变的基于聚氨酯的材料制造微制剂治疗致动器。在高于温度的温度下，Tg材料是柔软的并且可以容易地重塑成另一种构型。当温度降低到温度Tg以下时，只要材料保持低于温度Tg，新形状就会被固定和锁定。将材料重新加热至高于Tg的温度时，材料将恢复到原来的形状。通过使用这种SMP材料，SMP微管可用作用于例如通过导管穿入动脉瘤等物质输送的保持/释放致动器。微管可以以各种尺寸制造，相变温度Tg对于预期的温度目标和预期用途是确定的。 SMP微管可以定位在沉积材料的周围或内部。 SMP释放机构可以使用各种加热装置，并且SMP微管可以包括用于增强光吸收的金属涂层。

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