专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

21. 发明申请

US20090239824A1 HYDROLYTICALLY-RESISTANT BORON-CONTAINING THERAPEUTICS AND METHODS OF USE 有权
标题翻译：含抗水解硼含量的治疗方法及使用方法
公开(公告)号：US20090239824A1
公开(公告)日：2009-09-24
申请号：US12270636
申请日：2008-11-13
申请人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
发明人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
IPC分类号： A61K31/69 , C07F5/02 , A61P31/04
CPC分类号： C07F5/025
摘要： Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
摘要翻译：公开了用于治疗由细菌或病毒引起的疾病的治疗剂的硼烷衍生物，包括苯并恶唑，苯并唑并苯并噻唑的组合物和方法，以及合成所述试剂及其组合物的方法。

22. 发明授权

US07968752B2 Hydrolytically-resistant boron-containing therapeutics and methods of use 有权
标题翻译：耐水解硼含量治疗剂及使用方法
公开(公告)号：US07968752B2
公开(公告)日：2011-06-28
申请号：US12270636
申请日：2008-11-13
申请人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
发明人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
IPC分类号： C07F9/02
CPC分类号： C07F5/025
摘要： Compositions and methods of use of borole derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
摘要翻译：公开了用于治疗由细菌或病毒引起的疾病的治疗剂的硼烷衍生物，包括苯并恶唑，苯并唑并苯并噻唑的组合物和方法，以及合成所述试剂及其组合物的方法。

23. 发明授权

US08106031B2 Hydrolytically-resistant boron-containing therapeutics and methods of use 有权
标题翻译：耐水解硼含量治疗剂及使用方法
公开(公告)号：US08106031B2
公开(公告)日：2012-01-31
申请号：US11743665
申请日：2007-05-02
申请人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
发明人： Ving Lee , Jacob J. Plattner , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Carolyn Bellinger-Kawahara , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro
IPC分类号： C07F5/02 , A61K31/69 , A61P31/00
CPC分类号： C07F5/025
摘要： Compositions and methods of use of boron derivatives, including benzoxaboroles, benzazaboroles and benzthiaboroles, as therapeutic agents for treatment of diseases caused by fungi, yeast, bacteria or viruses are disclosed, as well as methods for synthesis of said agents and compositions thereof.
摘要翻译：公开了用于治疗由真菌，酵母，细菌或病毒引起的疾病的治疗剂的硼衍生物，包括苯并恶唑，苯并唑并苯并噻唑的组合物和方法，以及合成所述试剂及其组合物的方法。

24. 发明授权

US08895534B2 Boron containing small molecules 有权
标题翻译：硼含有小分子
公开(公告)号：US08895534B2
公开(公告)日：2014-11-25
申请号：US12848051
申请日：2010-07-30
申请人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
发明人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
IPC分类号： C07F5/02
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/387
摘要： Novel monosubstituted and disubstutituted oxaboroles and pharmaceutical compositions containing such oxaboroles are provided, which are useful for treating bacterial infections, as well as combinations of these oxaboroles with at least one additional therapeutically effective agent.
摘要翻译：提供了新的单取代和二取代的奥沙伏醇和含有这种恶唑烷的药物组合物，其可用于治疗细菌感染，以及这些恶唑烷与至少一种另外的治疗有效药剂的组合。

25. 发明申请

US20090227541A1 BORON-CONTAINING SMALL MOLECULES 有权
标题翻译：含硼的小分子
公开(公告)号：US20090227541A1
公开(公告)日：2009-09-10
申请号：US12142692
申请日：2008-06-19
申请人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
发明人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
IPC分类号： A61K31/69 , C07F5/02 , C12N9/99 , C12N1/36 , A61P31/04
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/387
摘要： This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗细菌感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

26. 发明申请

US20100292504A1 BORON-CONTAINING SMALL MOLECULES 有权
标题翻译：含硼的小分子
公开(公告)号：US20100292504A1
公开(公告)日：2010-11-18
申请号：US12848051
申请日：2010-07-30
申请人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
发明人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
IPC分类号： C07F5/02
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/387
摘要： This invention provides, among other things, novel compounds useful for treating bacterial infections, pharmaceutical compositions containing such compounds, as well as combinations of these compounds with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了可用于治疗细菌感染的新化合物，含有这些化合物的药物组合物，以及这些化合物与至少一种另外的治疗有效药物的组合。

27. 发明授权

US07816344B2 Boron-containing small molecules 有权
标题翻译：含硼的小分子
公开(公告)号：US07816344B2
公开(公告)日：2010-10-19
申请号：US12142692
申请日：2008-06-19
申请人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
发明人： Stephen J. Baker , Vincent S. Hernandez , Rashmi Sharma , James A. Nieman , Tsutomu Akama , Yong-Kang Zhang , Jacob J. Plattner , Michael Richard Kevin Alley , Rajeshwar Singh , Fernando Rock
IPC分类号： A61K31/69 , C07D493/00
CPC分类号： C07F5/025 , A61K31/69 , Y02A50/387
摘要： This invention provides, among other things, novel oxaboroles which are monosubstituted at the 3-, 6-, or 7-position, or disubstituted at the 3-/6- or 3-/7- positions, which are useful for treating bacterial infections, pharmaceutical compositions containing such oxaboroles, as well as combinations of these oxaboroles with at least one additional therapeutically effective agent.
摘要翻译：本发明尤其提供了在3-，6-或7-位单取代的或在3- / 6-或3- / 7-位二取代的新的恶唑烷，其可用于治疗细菌感染，含有这种恶唑烷的药物组合物，以及这些恶唑烷与至少一种另外的治疗有效药剂的组合。

28. 发明授权

US07888356B2 Antibiotics containing borinic acid complexes and methods of use 有权
标题翻译：含有硼酸配合物的抗生素及其使用方法
公开(公告)号：US07888356B2
公开(公告)日：2011-02-15
申请号：US11971693
申请日：2008-01-09
申请人： Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajesjwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
发明人： Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajesjwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
IPC分类号： A61K31/47 , A61P31/04 , A61P31/10 , C07D487/04 , C07D215/02 , C07D239/70 , C07D253/08
CPC分类号： C07F5/025
摘要： The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
摘要翻译：公开了包含硼酸络合物的抗生素的结构和制备，特别是羟基喹啉，咪唑和吡啶甲酸衍生物，以及这些抗生素的组合物以及使用抗生素和组合物作为杀菌和杀真菌剂的方法以及用于治疗细菌和真菌引起的疾病。

29. 发明授权

US07390806B2 Antibiotics containing borinic acid complexes and methods of use 有权
标题翻译：含有硼酸配合物的抗生素及其使用方法
公开(公告)号：US07390806B2
公开(公告)日：2008-06-24
申请号：US10867465
申请日：2004-06-14
申请人： Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
发明人： Ving Lee , Stephen J. Benkovic , Stephen J. Baker , Kirk R. Maples , Tsutomu Akama , Yong-Kang Zhang , Rajeshwar Singh , Vittorio A. Sauro , Chetan Pandit , Zhuoyi Su , Zhixiang Yang
IPC分类号： C07D484/04 , C07D215/02 , C07D215/20 , C07D239/70 , C07D253/08 , A61K31/47 , A61P31/04 , A61P31/10
CPC分类号： C07F5/025
摘要： The structure and preparation of antibiotics incorporating borinic acid complexes are disclosed, especially hydroxyquinoline, imidazole and picolinic acid derivatives, along with compositions of these antibiotics and methods of using the antibiotics and compositions as bactericidal and fungicidal agents as well as therapeutic agents for the treatment of diseases caused by bacteria and fungi.
摘要翻译：公开了包含硼酸络合物的抗生素的结构和制备，特别是羟基喹啉，咪唑和吡啶甲酸衍生物，以及这些抗生素的组合物以及使用抗生素和组合物作为杀菌和杀真菌剂的方法以及用于治疗细菌和真菌引起的疾病。

30. 发明授权

US5384719A Image generator for simulating the illumination effects of a vehicle-mounted light source on an image displayed on a screen 失效
标题翻译：用于模拟车载光源对屏幕上显示的图像的照明效果的图像发生器
公开(公告)号：US5384719A
公开(公告)日：1995-01-24
申请号：US960402
申请日：1993-01-15
申请人： Stephen J. Baker , Karl J. Wood , Graham J. Olive , Jeffrey N. Smith
发明人： Stephen J. Baker , Karl J. Wood , Graham J. Olive , Jeffrey N. Smith
IPC分类号： G09B9/32 , G06T15/50 , G09B9/30 , G06F15/60
CPC分类号： G06T15/506 , G09B9/301
摘要： A method and apparatus for simulating the illumination effects of a vehicle-mounted light source in an image displayed on a screen. The image is intended to represent the appearance of a model defined in a database in world space coordinates from and eyepoint position in world space, the model being defined in terms of a plurality of features each having predetermined attributes. The vehicle-mounted light source is defined in terms of an origin and a direction in eyepoint space. For each feature potentially contributing to the image, the angular position of a point on that feature relative to the light source is calculated as the angle between the light source direction and a line drawn to that point from the light source. An illumination intensity for that point is determined by reference to the calculated angle, and the illumination intensity is reduced as a function of the distance from the eyepoint to the said point to provide a resultant intensity. The attributes of the feature at the said point are modulated as a function of the resultant intensity.
摘要翻译： PCT No.PCT / GB91 / 00884 Sec。 371日期：1993年1月15日 102（e）日期1993年1月15日PCT Filed Jun。3，1991 PCT Pub。公开号WO91 / 19280 日期1991年12月12日。一种用于模拟车载光源在屏幕上显示的图像中的照明效果的方法和装置。该图像旨在表示在世界空间中的世界空间坐标和眼点位置的数据库中定义的模型的外观，该模型根据具有预定属性的多个特征来定义。车载光源根据眼点空间中的原点和方向来定义。对于潜在地对图像有贡献的每个特征，该特征相对于光源的点的角位置被计算为光源方向与从光源绘制到该点的线之间的角度。通过参照计算出的角度确定该点的照明强度，并且照射强度作为从眼点到所述点的距离的函数减小以提供合成的强度。所述点处的特征的属性作为合成强度的函数被调制。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式