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21. 发明授权

US07939100B2 Tulobuterol adhesive patch 有权
标题翻译：杜洛替罗胶贴
公开(公告)号：US07939100B2
公开(公告)日：2011-05-10
申请号：US10585168
申请日：2004-12-21
申请人： Naohisa Kawamura , Hidenori Sawada , Yoshiki Sugizaki , Takashi Saitoh
发明人： Naohisa Kawamura , Hidenori Sawada , Yoshiki Sugizaki , Takashi Saitoh
IPC分类号： A61F13/02 , A61L15/16 , A61F13/00 , A61K9/70 , A61K31/15 , A01N33/26
CPC分类号： A61K9/7061 , A61K31/137
摘要： The present invention provides a tulobuterol adhesive patch comprising (a) a support, (b) an acrylic pressure-sensitive adhesive layer containing the percutaneously absorbing drug tulobuterol and if necessary a lipophilic oily plasticizer, and (c) a release liner, laminated in that order, wherein the acrylic pressure-sensitive adhesive is a copolymer obtained by copolymerizing an acrylic monomer which is acetoacetoxyalkyl (meth) acrylate with one or more other vinyl monomers, to yield a tulobuterol adhesive patch with excellent release and skin permeability of tulobuterol from the pressure-sensitive adhesive layer, low skin irritation and excellent safety.
摘要翻译：本发明提供了一种吐洛罗酸粘合贴片，其包含（a）载体，（b）含有经皮吸收药物十四内罗酮和必要时的亲脂性油性增塑剂的丙烯酸类压敏粘合剂层，和（c）层压的剥离衬垫其中丙烯酸类压敏粘合剂是通过使（甲基）丙烯酸乙酰乙酰氧基烷基酯与一种或多种其它乙烯基单体共聚的丙烯酸单体而获得的共聚物，以产生具有良好的脱氢和皮肤渗透性的十四指醇粘合剂贴剂，敏感性粘合剂层，皮肤刺激性低，安全性好。

22. 发明授权

US07529430B2 System and method for displaying an image indicating a positional relation between partially overlapping images 失效
标题翻译：用于显示指示部分重叠图像之间的位置关系的图像的系统和方法
公开(公告)号：US07529430B2
公开(公告)日：2009-05-05
申请号：US11668511
申请日：2007-01-30
申请人： Koichi Ejiri , Shin Aoki , Takashi Saitoh , Guan Haike , Takuji Sakamoto
发明人： Koichi Ejiri , Shin Aoki , Takashi Saitoh , Guan Haike , Takuji Sakamoto
IPC分类号： G06K9/36
CPC分类号： H04N5/772 , G06T7/223 , G06T7/30 , G06T7/73 , G06T2200/24 , G06T2200/32 , G06T2207/10016 , G06T2207/20021 , H04N5/23238 , H04N5/23293 , H04N5/907
摘要： A device includes a display monitor configured to display on a screen of the display monitor at least one of a current image and a preceding image taken by an optical unit, a storage unit configured to store the preceding image, and a control unit configured to display a part of the preceding image on the screen when the current image is displayed on the screen, the displayed part of the preceding image indicating a positional relationship between the current image and the preceding image. The current image is taken when the displayed part of the preceding image substantially overlaps a corresponding portion of the current image such that the current image and the preceding image can be processed to form a panoramic image.
摘要翻译：一种设备包括显示监视器，被配置为在显示监视器的屏幕上显示由光学单元拍摄的当前图像和先前图像中的至少一个，被配置为存储前一图像的存储单元和被配置为显示的控制单元在当前图像显示在屏幕上时屏幕上的前一图像的一部分，前一图像的显示部分指示当前图像和前一图像之间的位置关系。当前一图像的显示部分基本上与当前图像的对应部分重叠时，拍摄当前图像，使得可以处理当前图像和前一图像以形成全景图像。

23. 发明申请

US20080220517A1 SITE-SPECIFIC CELL PERFORATION TECHNIQUE 审中-公开
标题翻译：网站特定细胞执行技术
公开(公告)号：US20080220517A1
公开(公告)日：2008-09-11
申请号：US11846378
申请日：2007-08-28
申请人： Isao Karube , Takashi Saitoh
发明人： Isao Karube , Takashi Saitoh
IPC分类号： C12N1/00
CPC分类号： C12N15/89 , C12M35/00 , C12N13/00
摘要： A technique for controlling membrane denaturation reactions other than physical shear force was developed. For example, the present invention provides, a method for causing membrane disruption at a specific site by reacting a stimulus such as light with a compound that is activated by the stimulus, where the reaction occurs on a membrane such as a biomembrane. It also provides a membrane structure such as cells in which a specific site has been disrupted, which are obtained by the present method. Introduction of substances such as genes also became possible by using this membrane structure. Further provided is a membrane-destroying member for disrupting a membrane at a specific site. Thus, the present invention enabled, for example, easy membrane penetration using components constituting microelectrodes, micromanipulators, and microinjectors, which were conventionally hardly usable in penetrating cell membranes.
摘要翻译：开发了除物理剪切力之外控制膜变性反应的技术。例如，本发明提供了通过使诸如光的刺激与由刺激激活的化合物反应而使特定部位的膜破裂的方法，其中反应发生在诸如生物膜的膜上。还提供了通过本方法获得的膜结构，例如其中特异性位点已被破坏的细胞。使用这种膜结构也可以引入基因等物质。还提供了用于破坏特定部位的膜的破坏薄膜的部件。因此，本发明能够例如使用通常几乎不能用于穿透细胞膜的微电极，显微操纵器和微注射器的构成的薄膜穿透。

24. 发明申请

US20070260194A1 Chemical Liquid Injection System 有权
标题翻译：化学液体注射系统
公开(公告)号：US20070260194A1
公开(公告)日：2007-11-08
申请号：US11720189
申请日：2005-06-09
申请人： Shigeru Nemoto , Takashi Saitoh
发明人： Shigeru Nemoto , Takashi Saitoh
IPC分类号： A61M5/315
CPC分类号： A61M5/1458 , A61M5/14546 , A61M5/1456
摘要： A piston adapter, which can be easily removed even when it is mounted on a piston member of a rodless syringe and pressed in a cylinder member, is provided. In piston adapter 200, when manual operation member 230 is manually rotated relative to adapter rod 210, adapter shaft 220 is also rotated to turn the trailing end of flange engagement member 240 engaging with an engagement open/close mechanism near leading end of the flange engagement member, thereby piston adapter 200 can be easily put on and removed from the piston member of the rodless syringe its leading end by manually operating the trailing end of piston adapter 200.
摘要翻译：提供一种活塞适配器，其即使在安装在无杆式注射器的活塞构件上并被压在气缸构件中时也能够容易地移除。在活塞适配器200中，当手动操作构件230相对于接头杆210手动旋转时，适配器轴220也旋转以使凸缘接合构件240的后端与接合开/闭机构接合，使其接近凸缘接合的前端因此活塞适配器200可以通过手动操作活塞适配器200的尾端而容易地从无杆注射器的活塞件前端引出和移除。

25. 发明申请

US20060256362A1 Embedding data into document and extracting embedded data from document 有权
公开(公告)号：US20060256362A1
公开(公告)日：2006-11-16
申请号：US11369964
申请日：2006-03-08
申请人： Haike Guan , Masaaki Ishikawa , Hiroshi Shimura , Takashi Saitoh , Hiroyuki Yoshida
发明人： Haike Guan , Masaaki Ishikawa , Hiroshi Shimura , Takashi Saitoh , Hiroyuki Yoshida
IPC分类号： G06K9/00 , G06K15/00
CPC分类号： H04N1/32203 , G06T1/0021 , G06T2201/0051 , H04N1/32224 , H04N1/32251 , H04N1/32309 , H04N1/32341 , H04N1/38
摘要： An apparatus, method, system, computer program and product, each capable of embedding data into a document or extracting embedded data from document. The data to be embedded may be embedded in the form of a plurality of patterns having a relative relationship.

26. 发明申请

US20060164693A1 Generating a protected document image having a visible verification image 审中-公开
标题翻译：生成具有可见验证图像的受保护文档图像
公开(公告)号：US20060164693A1
公开(公告)日：2006-07-27
申请号：US11288172
申请日：2005-11-29
申请人： Tsutomu Matsumoto , Takashi Saitoh , Yasushi Abe , Masaki Ishii , Takayuki Hara
发明人： Tsutomu Matsumoto , Takashi Saitoh , Yasushi Abe , Masaki Ishii , Takayuki Hara
IPC分类号： H04N1/40
CPC分类号： H04N1/32144 , H04N2201/3236 , H04N2201/325 , H04N2201/3271 , H04N2201/3281
摘要： An apparatus, method, system, computer program and product for generating a protected document image having a visible verification image. Using the visible verification image, the integrity of the protected document image can be visually checked without requiring machine intervention.
摘要翻译：一种用于生成具有可见验证图像的受保护文档图像的装置，方法，系统，计算机程序和产品。使用可见的验证图像，可以直观地检查受保护的文档图像的完整性，而不需要机器干预。

27. 发明申请

US20050198903A1 Window regulator apparatus 审中-公开
标题翻译：窗户调节装置
公开(公告)号：US20050198903A1
公开(公告)日：2005-09-15
申请号：US11075814
申请日：2005-03-09
申请人： Yukio Isomura , Shigeyuki Suzuki , Takashi Saitoh
发明人： Yukio Isomura , Shigeyuki Suzuki , Takashi Saitoh
IPC分类号： B60J1/17 , E05F11/44 , E05F15/08 , E05F15/16 , H02K5/22 , H02K7/00 , H02K7/116
CPC分类号： E05F11/445 , E05F15/697 , E05Y2900/55 , H02K5/225 , H02K7/1166
摘要： A window regulator apparatus includes a housing supporting an electrically driving source, accommodating therein a speed reduction gear mechanism, and secured to an inner panel of a vehicle door; a case formed integrally with the housing and within which installing a driving circuit substrate, the case having a first surface facing the inner panel of the vehicle door and further having an opening defined at a portion of the case being different from the first surface, the opening employed as a means of inserting the driving circuit substrate into the case; a connector connected to the driving circuit substrate, exposed to an area outside the case through the first surface, and facing the inner panel of the vehicle door; and a sealing member supported at the case so as to protect and make fluid-tight a periphery of the connector.
摘要翻译：一种窗口调节装置，包括：支撑电动驱动源的壳体，容纳减速齿轮机构，并固定在车门的内板上; 与所述壳体一体形成的壳体，其中安装驱动电路基板，所述壳体具有面向所述车门的内板的第一表面，并且还具有限定在所述壳体的与所述第一表面不同的部分的开口，作为将驱动电路基板插入壳体中的装置; 连接到所述驱动电路基板的连接器，通过所述第一表面暴露于所述壳体外部的区域，并且面向所述车门的内板; 以及密封构件，其被支撑在所述壳体处以便保护并使所述连接器的周边不流体密封。

28. 发明申请

US20050151990A1 Method, computer program, and apparatus for detecting specific information included in image data of original image with accuracy, and computer readable storing medium storing the program 有权
标题翻译：用于准确地检测原始图像的图像数据中包含的特定信息的方法，计算机程序和装置，以及存储程序的计算机可读存储介质
公开(公告)号：US20050151990A1
公开(公告)日：2005-07-14
申请号：US10982976
申请日：2004-11-08
申请人： Masaaki Ishikawa , Takashi Saitoh , Hiroshi Shimura , Haike Guan
发明人： Masaaki Ishikawa , Takashi Saitoh , Hiroshi Shimura , Haike Guan
IPC分类号： G03C5/08 , G03G21/04 , H04N1/00 , G06F3/12 , B42D15/00 , G06K9/46 , G06K9/80
CPC分类号： H04N1/00846 , G03C5/08 , G03G21/043 , H04N1/00875 , H04N1/00883
摘要： An image processing apparatus includes an image input device that reads an original image and obtains image data from the original image by selecting one of plural types of image reading modes of the image input device, an image pre-processing mechanism that performs at least one pre-processing relative to the image data obtained by the image input device, an image pre-processing selecting mechanism that selects at least one pre-processing according to the image reading mode selected by the image input device and causes the image pre-processing mechanism to perform the selected at least one pre-processing, and an information extracting mechanism that extracts specific information included in the image data subjected to the at least one pre-processing performed by the image pre-processing mechanism.
摘要翻译：图像处理装置包括：图像输入装置，其通过选择图像输入装置的多种图像读取模式中的一种来读取原始图像并从原始图像获得图像数据;图像预处理机构，其执行至少一个预处理处理相对于由图像输入装置获得的图像数据的处理;图像预处理选择机构，其根据由图像输入装置选择的图像读取模式选择至少一个预处理，并使图像预处理机构执行所选择的至少一个预处理，以及信息提取机制，其提取经过由图像预处理机构执行的至少一个预处理的图像数据中包括的特定信息。

29. 发明授权

US06901236B2 Method, program, and apparatus for preventing a reproduction of an anti-copy document, and a medium storing the program 有权
标题翻译：用于防止复制文件的再现的方法，程序和装置，以及存储程序的介质
公开(公告)号：US06901236B2
公开(公告)日：2005-05-31
申请号：US10663743
申请日：2003-09-17
申请人： Takashi Saitoh , Haike Guan , Yasushi Abe
发明人： Takashi Saitoh , Haike Guan , Yasushi Abe
IPC分类号： G06T1/00 , G06F21/00 , H04N1/00 , H04N1/40 , G03G21/00
CPC分类号： H04N1/00843 , G06F21/10 , G06F2221/0737 , H04N1/00859
摘要： An image processing apparatus includes a scanning mechanism, first and second memories, an image accumulating mechanism, a detecting mechanism, a determining mechanism, and a code assigning mechanism. The first memory stores a reference dot pattern indicating an anti-copy background dot pattern. The second memory stores image data. The image accumulating mechanism accumulates image data of an original image into the second memory. The detecting mechanism detects a background dot pattern embedded in a background image included in the image data of the accumulated original image. The determining mechanism compares the detected background dot pattern with the reference dot pattern and determines whether the detected background dot pattern is substantially identical to the reference dot pattern. The code assigning mechanism assigns an identification code to the image data having the detected background dot pattern when the detected background dot pattern is determined as substantially identical to the reference dot pattern.
摘要翻译：图像处理装置包括扫描机构，第一和第二存储器，图像存储机构，检测机构，确定机构和代码分配机构。第一存储器存储指示防复制背景点图案的参考点图案。第二存储器存储图像数据。图像累积机构将原始图像的图像数据累积到第二存储器中。检测机构检测嵌入在累积的原始图像的图像数据中的背景图像中的背景点图案。确定机构将检测到的背景点图案与参考点图案进行比较，并且确定检测到的背景点图案是否与参考点图案基本相同。当检测到的背景点图案被确定为与参考点图案基本相同时，代码分配机构向具有检测到的背景点图案的图像数据分配识别码。

30. 发明授权

US06884433B2 Sustained release formulation containing tacrolimus 有权
标题翻译：含有他克莫司的缓释制剂
公开(公告)号：US06884433B2
公开(公告)日：2005-04-26
申请号：US10412281
申请日：2003-04-14
申请人： Kazunari Yamashita , Eiji Hashimoto , Yukihiro Nomura , Fumio Shimojo , Shigeki Tamura , Takeo Hirose , Satoshi Ueda , Takashi Saitoh , Rinta Ibuki , Toshio Ideno
发明人： Kazunari Yamashita , Eiji Hashimoto , Yukihiro Nomura , Fumio Shimojo , Shigeki Tamura , Takeo Hirose , Satoshi Ueda , Takashi Saitoh , Rinta Ibuki , Toshio Ideno
IPC分类号： C07H15/04 , A61K20060101 , A61K9/10 , A61K9/14 , A61K9/16 , A61K9/20 , A61K9/22 , A61K9/48 , A61K9/52 , A61K31/40 , A61K31/405 , A61K31/407 , A61K31/4353 , A61K31/436 , A61K31/453 , A61K31/706 , A61K47/04 , A61K47/12 , A61K47/14 , A61K47/26 , A61K47/32 , A61K47/36 , A61K47/38 , A61K47/40 , A61P31/00 , A61P37/06 , C07D498/18 , G01N33/15 , A61K9/00 , A61K31/44
CPC分类号： A61K31/453 , A61K9/141 , A61K9/143 , A61K9/145 , A61K9/146 , A61K9/1617 , A61K9/1623 , A61K9/1635 , A61K9/1641 , A61K9/1647 , A61K9/1652 , A61K9/4858 , A61K31/407 , A61K31/436
摘要： Sustained release formulation containing tacrolimus or its hydrate is provided. The time (T63.2%) required for 63.2% of the maximum amount of tacrolimus or its hydrate to be dissolved is 0.7 to 15 hours. The time is measured in accordance to the Japanes Pharmacopocia, the 13-th edition, Dissolution Test, No. 2 (Puddles method, 50 rpm) using an aqueous 0.005% hydroxypropyl cellulose solution. This aqueous test solution is adjusted to pH 4.5, accordingly. The formulation further comprises a solid base which is a water-soluble or water-insoluble polymer. The formulation is in the form of a powder, fine powder, granule, tablet or capsule. The formulation is administered to a patient once a day for preventing organ or tissue rejection by transplantation or autoimmune disease. In addition, a solid dispersion composition is provided. The solid dispersion comprises tacrolimus or its hydrate in a mixture containing water-soluble or water-insoluble polymer and an excipient.
摘要翻译：提供含他克莫司或其水合物的缓释制剂。最高量的他克莫司或其水合物溶解63.2％所需的时间（T63.2％）为0.7〜15小时。该时间根据Japanes Pharmacopocia，第13版，溶出度试验，2号（Puddles法，50rpm），使用0.005％羟丙基纤维素水溶液测量。相应地将该水性测试溶液调节至pH 4.5。该制剂还包含固体碱，其为水溶性或水不溶性聚合物。制剂为粉末，细粉，颗粒，片剂或胶囊的形式。该制剂每天一次施用于患者，以通过移植或自身免疫疾病预防器官或组织排斥反应。此外，提供了固体分散体组合物。固体分散体包含他克莫司或其水合物，其含有水溶性或水不溶性聚合物和赋形剂的混合物。

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