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21. 发明专利

BRPI0715639A2 未知
公开(公告)号：BRPI0715639A2
公开(公告)日：2013-07-02
申请号：BRPI0715639
申请日：2007-07-30
申请人： SMITHKLINE BEECHAM CORP
发明人： ADUSUMILLI PRASAD , LECH STANLEY J , DENG FANG
IPC分类号： A61C13/23 , A61K6/884

22. 发明专利

MX2009000294A SISTEMA Y METODO PARA FABRICAR DENTADURAS COMPLETAS Y PARCIALES. 未知
公开(公告)号：MX2009000294A
公开(公告)日：2009-02-25
申请号：MX2009000294
申请日：2007-07-02
申请人： SMITHKLINE BEECHAM CORP
发明人： LECH STANLEY J , ADUSUMILLI PRASAD
IPC分类号： A61C13/08
摘要： Se proporciona un sistema para fabricar al menos una porción de una dentadura; el sistema incluye un dispositivo de escaneo tridimensional para escanear una superficie de una plantilla de dentadura y un medio legible para computadora que incluye un programa de computadora para recibir datos del dispositivo de escaneo, creando un modelo tridimensional de la superficie y opcionalmente modificando el modelo tridimensional y/o añadir características al modelo tridimensional; el sistema también incluye un fabricador para crear la al menos una porción de la dentadura a partir de un material seleccionado, con base en el modelo tridimensional; el fabricador puede ser un dispositivo que incluye un torno o una máquina de prototipo rápido; también se proporciona un método para fabricar al menos una porción de una dentadura.

23. 发明专利

AU2002252470B2 Nicotine containing oral dosage form 未知
公开(公告)号：AU2002252470B2
公开(公告)日：2008-05-22
申请号：AU2002252470
申请日：2002-03-22
申请人： SMITHKLINE BEECHAM CORP
发明人： LECH STANLEY J , LIU JOHN , PLATCOW STUART
IPC分类号： A61K9/20 , A61K9/00 , A61K31/465 , A61K47/02 , A61K47/10 , A61K47/26 , A61P25/34

24. 发明专利

CA2655738A1 SYSTEM AND METHOD FOR MANUFACTURING FULL AND PARTIAL DENTURES 未知
公开(公告)号：CA2655738A1
公开(公告)日：2008-01-10
申请号：CA2655738
申请日：2007-07-02
申请人： SMITHKLINE BEECHAM CORP
发明人： LECH STANLEY J , ADUSUMILLI PRASAD
IPC分类号： G06F19/00 , A61C3/00 , A61C8/00
摘要： There is provided a system for fabricating 100 at least a portion of a de nture. The system includes a three-dimensional scanning device 105 for scann ing a surface of a denture template, and a computer-readable medium 110 incl uding a computer program for receiving data from the scanning device, creati ng a 3-dimensional model 315 of the surface, and optionally modifying the 3- dimensional model 315 and/or adding features to the 3- dimensional model 315 . The system also includes a fabricator 115 for creating the at least the po rtion of the denture, from a selected material, based on the 3- dimensional model. The fabricator 115 may be a device including a lathe 805, or a rapid prototyping machine. There is also provided a method for fabricating at leas t a portion of a denture 810.

25. 发明专利

AU2006318251A1 Adhesive liner 未知
公开(公告)号：AU2006318251A1
公开(公告)日：2007-05-31
申请号：AU2006318251
申请日：2006-11-20
申请人： SMITHKLINE BEECHAM CORP
发明人： LECH STANLEY J , WILENSKY STUART B , WONG EDDIE , BIDDESCOMB JOHN R
IPC分类号： A61C13/12 , A61K6/884
摘要： The present invention provides a denture adhesive liner in the form of an extruded film or sheet, comprising a denture adhesive effective amount of alginate; thermoplastic polymer; and plasticizer, wherein said composition is extrudable into a film that is capable of adhering to a wet mucous surface. The present invention also provides a method for preparing a denture adhesive liner comprising the steps of: preparing a composition of a denture adhesive effective amount of alginate; thermoplastic polymer; and plasticizer; and forming a denture adhesive liner from the composition.

26. 发明专利

PE05162005A1 COMPOSICIONES DISOLVENTES DE ADHESIVOS DE DENTADURA 未知
公开(公告)号：PE05162005A1
公开(公告)日：2005-07-22
申请号：PE0009672004
申请日：2004-10-04
申请人： SMITHKLINE BEECHAM CORP
发明人： CLARKE HAL C , LECH STANLEY J , MEHTA NARESH I
IPC分类号： A61K6/00 , A61K8/25 , A61K8/31 , A61K8/34 , A61K8/44 , A61K8/46 , A61K8/92 , A61Q11/00 , A61Q11/02 , C11D1/14 , C11D3/12 , C11D3/18 , C11D3/43 , C11D3/44 , A61K7/16
CPC分类号： A61K8/345 , A61K6/0017 , A61K6/0023 , A61K6/0067 , A61K6/0088 , A61K6/0091 , A61K8/25 , A61K8/31 , A61K8/463 , A61K8/922 , A61Q11/02 , C11D1/146 , C11D3/124 , C11D3/18 , C11D3/188 , C11D3/43
摘要： QUE COMPRENDE: 1)AL MENOS UN DISOLVENTE BASADO EN ACEITE, SELECCIONADO DE: ACEITE MINERAL, ACEITE VEGETAL, D-LIMOLENO, GLICERINA, ACEITE DE SEMILLA DE ALGODON, ACEITE DE SESAMO, PROPILENGLICOL Y MEZCLAS DE LOS MISMOS; 2)1% A 50%, EN PESO DE LA COMPOSICION, DE UN ESPESANTE, TAL COMO DIOXIDO DE SILICIO; 3)0,1% A 15%, EN PESO, DE UN AGENTE TENSIOACTIVO, TAL COMO LAURILSULFATO DE SODIO; 4)1% A 50% DE AGUAL; 5)0,1% A 10%, EN PESO DE LA COMPOSICION, DE UN AROMATIZANTE; Y, OPCIONALMENTE, 6)AGENTES ANTI-CALCULO, AGENTES ANTI-CARIES TALES COMO FUENTES DE ION FLUORURO, AGENTES BLANQUEANTES, REFRESCANTES DEL ALIENTO, AGENTES ANTI-MICROBIANOS, NUTRIENTES, ANTIOXIDANTES, AGENTES ANALGESICO, ANTIHISTAMINICOS, VASOCONSTRICTORES, HEMOSTATICOS, ANTIFUNGICOS, ANTIHIPERTENSIVOS, ANTIEMETICOS, ANTIARRITMICOS, HORMONAS, INHIBIDORES DE BOMBEO DE PROTONES, PIGMENTOS, TINTES, ENTRE OTROS, Y MEZCLAS DE LOS MISMOS. SE REFIERE TAMBIEN A UN SISTEMA DE ELIMINACION DEL ADHESIVO DE DENTADURA, QUE COMPRENDE UNA TOALLITA, QUE CONTIENE UN SUSTRATO FLEXIBLE QUE ESTA PREHUMEDECIDO CON LA COMPOSICION DISOLVENTE DESCRITA

27. 发明专利

NZ528167A Nicotine-containing oral dosage form 未知
公开(公告)号：NZ528167A
公开(公告)日：2005-04-29
申请号：NZ52816702
申请日：2002-03-22
申请人： SMITHKLINE BEECHAM CORP
发明人： LIU JOHN , LECH STANLEY J , PLATCOW STUART
IPC分类号： A61K9/20 , A61K9/00 , A61K31/465 , A61K47/02 , A61K47/10 , A61K47/26 , A61P25/34 , A61K31/715 , A61K9/14
摘要： Disclosed herein is a solid, oral dosage form useful for transmucosal oral administration of a nicotine active, comprising: (a) a glassy matrix base component comprising at least one substantially non-hygroscopic sugar alcohol capable of forming a glassy structure; and (b) a nicotine active from 0.5 mg to 5 mg per dosage unit, and wherein the dosage form is orally dissolvable; and wherein the amount of nicotine active is effective to reduce nicotine cravings.

28. 发明专利

CA2383405A1 PROCESS FOR MAKING AQUEOUS COATED BEADLETS 未知
公开(公告)号：CA2383405A1
公开(公告)日：2001-03-22
申请号：CA2383405
申请日：2000-09-14
申请人： SMITHKLINE BEECHAM CORP
发明人： ACHANTA ANAND , ADUSUMILLI PRASAD , LECH STANLEY J , OTHS PHIL , DESHPANDE GANESH , VINEN ARTHUR , WALSH BRENDAN
IPC分类号： A61K9/16 , A61K9/22 , A61K9/26 , A61K9/50 , A61K9/54 , A61K31/137 , A61K31/192 , A61K31/4402 , A61K31/485 , A61K47/32 , A61K47/38 , A61P11/04 , A61K9/14 , A61K9/20
摘要： The present invention is directed to application of novel process conditions for aqueous coating techniques of water soluble active agents, and its application to production of sustained release beadlets of said agents. The improvement lies in the determination and use of the glass transition point for the water swellable polymer used to produce the sustained release effect , and control of the moisture content of the air by dew point.

29. 发明专利

BRPI0714868A2 未知
公开(公告)号：BRPI0714868A2
公开(公告)日：2013-05-28
申请号：BRPI0714868
申请日：2007-08-30
申请人： SMITHKLINE BEECHAM CORP
发明人： DULLEA CHARLES V , LECH STANLEY J , DENG FANG
IPC分类号： C11D1/72
摘要： This invention relates to a new denture care composition and method of use. In particular, this invention relates to a film-forming denture care composition that kills odor causing bacteria, maintains prolonged fresh breath for two or more hours and is an effective guard against denture odor.

30. 发明专利

BRPI0618828A2 未知
公开(公告)号：BRPI0618828A2
公开(公告)日：2011-09-13
申请号：BRPI0618828
申请日：2006-11-20
申请人： SMITHKLINE BEECHAM CORP
发明人： DENG FANG , LECH STANLEY J
IPC分类号： A61C13/02 , A61F13/00
摘要： The present invention provides a foamed and/or aerated substrate for transmucosal and/or transdermal applications. The foamed and/or aerated substrate may be in the form of a film, sheet, strip or wafer. The foamed and/or aerated substrate is suitable for use in applications such as, for example, adhesive denture liners, tooth whitening, and smoking control/cessation. The foamed and/or aerated substrate is polymeric in nature and comprises one or more polymers and one or more foaming agents. Additionally, the foamed and/or aerated substrate may include, but not limited to, one or more plasticizers, hydrophobic barrier agents, tooth whitening agents, antioxidants, preservatives, super-disintegrants or absorbents, flavorants, deodorants, breath freshening agents, colorants, surfactants, film modifiers, cross-linking agents, antimicrobial agents, control release agents, other therapeutic agents, or any combinations thereof.

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