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21. 发明申请

US20070265490A1 LEFT VENTRICLE ASSIST DEVICE (LVAD) 有权
标题翻译：左侧通气辅助装置（LVAD）
公开(公告)号：US20070265490A1
公开(公告)日：2007-11-15
申请号：US11679487
申请日：2007-02-27
申请人： Robert Smith , Roger Snyder , Adrian Kantrowitz , Allen Kantrowitz
发明人： Robert Smith , Roger Snyder , Adrian Kantrowitz , Allen Kantrowitz
IPC分类号： A61M1/10
CPC分类号： A61M1/1072 , A61M1/1008 , A61M1/1037 , A61M1/106 , A61M1/122 , A61M1/125
摘要： A blood pump for placement in an incision in an aorta is provided that after placement contacts blood passing through the aorta. The pump inflates and deflates in order to provide left ventricular assistance. The pump has an elongated shell with a generally elliptical shape, an outer convex surface and an inner concave surface. A peripheral side edge located between the inner and outer surfaces terminates in a bead edge. A passage is provided through the shell to provide fluid communication between the outer surface and inner surface. A flexible airtight membrane has a membrane edge bonded to the outer shell surface adjacent to the bead edge to form an enclosed internal chamber in fluid communication with the passage. Preforming the membrane edge looped with a maximum linear span of curvature that is greater than a maximal transverse linear extent of the bead edge, membrane operational wear during inflation and deflation cycles is reduced in the region around the bead edge. A process of forming a blood pump with a membrane preform is provided that includes placing an airtight membrane around a platen having a platen edge bead with a curvature of maximal transverse linear extent and a platen footprint substantially identical to a footprint of the blood pump shell. By heat setting the membrane, a looped membrane edge is formed as complementary to the curvature of the platen edge bead to yield a membrane preform. The membrane preform is secured to the outer surface of the shell having a bead edge of maximum linear extent less than the curvature of the looped membrane edge.
摘要翻译：提供用于放置在主动脉切口中的血泵，其在放置后接触通过主动脉的血液。泵充气和放气以提供左心室辅助。泵具有大致椭圆形的细长壳体，外凸面和内凹面。位于内表面和外表面之间的周边侧边缘终止于边缘。通过壳体提供通道以在外表面和内表面之间提供流体连通。柔性密封膜具有与胎圈边缘相邻的外壳表面结合的膜边缘，以形成与通道流体连通的封闭内部室。预先形成最大线性曲率跨度的膜边缘，其大于胎圈边缘的最大横向线性范围，在充气和放气周期期间的膜操作磨损在珠边缘周围的区域减小。提供了一种形成具有膜预制件的血液泵的过程，其包括将气密膜放置在具有最大横向线性范围的曲率的台板边缘珠的压板上，和与血泵壳的占地面积基本相同的压板盖板。通过热定形膜，形成环形膜边缘，以与压板边缘珠的曲率互补以产生膜预制件。膜预制件被固定到外壳的外表面，其具有小于环形膜边缘的曲率的最大线性范围的边缘边缘。

22. 发明申请

US20060030747A1 Synchronization system between aortic valve and cardiac assist device 有权
公开(公告)号：US20060030747A1
公开(公告)日：2006-02-09
申请号：US11178969
申请日：2005-07-11
申请人： Allen Kantrowitz , Adrian Kantrowitz
发明人： Allen Kantrowitz , Adrian Kantrowitz
IPC分类号： A61N1/362
CPC分类号： A61M1/122 , A61M1/106 , A61M1/1067 , A61M1/1072 , A61M1/1086 , A61M1/12 , A61M1/127 , A61M2205/33 , A61M2205/3303
摘要： A cardiac assist device synchronization system includes a cardiac assist device and an acoustic or accelerometer sensor that provides a signal input to the cardiac assist device indicative of aortic valve closure. The cardiac assist device is coupled to a mammalian aorta and includes an inflatable chamber and a fluid pump. A fluid conduit is in communication between the chamber and the pump to provide for selective inflation of the chamber. A pump controller triggers the pump in counter-pulsation to a mammalian heart upstream from the aorta. A process for synchronizing a cardiac assist device in counter-pulsation with a left ventricle includes locating an acoustic or accelerometer sensor within a thoracic cavity of a mammal having the assist device coupled to the aorta of the mammal. Through the measurement of an acoustic or acceleration property of an aortic valve of the mammal, and the transmission of aortic valve closure measurement through a controller for the cardiac assist device, counter-pulsatile synchronization for the cardiac assist device is achieved.

23. 发明授权

US06503228B1 Protective assembly for a percutaneous access device 有权
标题翻译：用于经皮进入装置的保护组件
公开(公告)号：US06503228B1
公开(公告)日：2003-01-07
申请号：US09539938
申请日：2000-03-31
申请人： Jun Li , Adrian Kantrowitz , Paul Freed , George Taro
发明人： Jun Li , Adrian Kantrowitz , Paul Freed , George Taro
IPC分类号： A61M532
CPC分类号： A61M39/0247 , A61M2039/0288
摘要： A protective assembly for a protruding portal shields a neck portion of the portal. The protective assembly is well suited for shielding a percutaneous access device during surgical implantation. The protective assembly includes a lid seating pin configured to seat within the interior of the portal and a lid secured to the pin extending over exterior portions of the portal and gapped from the portal face and the neck. Optionally, the pin inserts within a temporary turret engaging the interior of the portal.
摘要翻译：用于突出入口的保护组件屏蔽门的颈部。保护组件非常适用于在手术植入期间屏蔽经皮进入装置。该保护组件包括盖座座钉，其配置成位于入口内部，以及固定到销上的盖，该盖延伸到门的外部部分并从入口面和颈部间隙。可选地，销插入临时转塔内，接合入口的内部。

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