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21. 发明申请

US20070203448A1 System and method for monitoring health using exhaled breath 有权
标题翻译：使用呼气监测健康的系统和方法
公开(公告)号：US20070203448A1
公开(公告)日：2007-08-30
申请号：US11512856
申请日：2006-08-29
申请人： Richard Melker , David Bjoraker , Samsun Lampotang
发明人： Richard Melker , David Bjoraker , Samsun Lampotang
IPC分类号： A61M16/01
CPC分类号： A61M16/01 , A61B5/082 , A61B5/14532 , A61B5/14546 , A61B5/411 , A61B5/4821 , A61B5/7267 , A61M16/0051 , A61M16/026 , A61M16/0808 , A61M16/0841 , A61M16/1045 , A61M16/18 , A61M16/22 , A61M2016/0036 , A61M2016/1035 , A61M2202/0275 , A61M2202/0486 , A61M2205/18 , A61M2205/3553 , A61M2205/3561 , A61M2205/3584 , A61M2205/52 , A61M2205/80 , A61M2230/43 , A61M2230/432 , A61M2230/435 , A61M2230/437 , G01N33/497
摘要： The present invention includes systems and methods for monitoring endogenous compound concentration in blood by detecting markers, such as odors, upon exhalation by a patient, wherein such markers are the endogenous compound itself or result from the endogenous compound. In the case of olfactory markers, the invention preferably utilizes electronic sensor technology, such as the commercial devices referred to as “artificial” or “electronic” noses or tongues, to non-invasively monitor endogenous compound levels in blood. The invention further includes a reporting system capable of tracking endogenous compound concentrations in blood (remote or proximate locations) and providing the necessary alerts with regard to emergent or harmful conditions in a patient.
摘要翻译：本发明包括通过在患者呼出时检测诸如气味等标记物的血液中的内源性化合物浓度的系统和方法，其中所述标志物是内源性化合物本身或由内源化合物产生。在嗅觉标记的情况下，本发明优选利用诸如称为“人造”或“电子”鼻子或舌头的商业装置的电子传感器技术非侵入性地监测血液中的内源性化合物水平。本发明还包括能够跟踪血液中的内源性化合物浓度（偏远或近处）并提供关于患者的紧急或有害状况的必要警报的报告系统。

22. 发明申请

US20050191326A1 Materials and methods for creating customized compositions having a temporary visual indicator 审中-公开
标题翻译：用于创建具有临时视觉指示符的定制组合物的材料和方法
公开(公告)号：US20050191326A1
公开(公告)日：2005-09-01
申请号：US10788541
申请日：2004-02-27
申请人： Richard Melker
发明人： Richard Melker
IPC分类号： A01N25/00 , A01N61/00 , G06F17/30 , G06Q50/00 , A61K7/42 , C08K5/48
CPC分类号： A01N25/00 , A01N61/00 , A01N2300/00
摘要： The present invention relates to novel compositions, which provide an indicator for location and/or concentration of the composition during application. In a preferred embodiment, the indicator is a compound that is visible at a first pH and invisible at a second pH. The composition includes the indicator and a volatile base or acid. The volatile base or acid enables the composition to be at a first pH so that the indicator is visible when first applied to a desired surface. However, upon evaporation or degradation of the volatile acid or base, the composition will be at a second pH, causing the indicator to disappear.
摘要翻译：本发明涉及新的组合物，其提供了施用期间组合物的位置和/或浓度的指示剂。在优选的实施方案中，指示剂是在第一pH下可见并且在第二pH下不可见的化合物。组合物包括指示剂和挥发性碱或酸。挥发性碱或酸使得组合物处于第一pH，使得当首次施加到所需表面时，指示剂是可见的。然而，当挥发性酸或碱的蒸发或降解时，组合物将处于第二pH，导致指示剂消失。

23. 发明授权

US06909912B2 Non-invasive perfusion monitor and system, specially configured oximeter probes, methods of using same, and covers for probes 有权
标题翻译：非侵入性灌注监测仪和系统，专门配置的血氧计探头，使用方法和探头盖
公开(公告)号：US06909912B2
公开(公告)日：2005-06-21
申请号：US10176310
申请日：2002-06-20
申请人： Richard Melker
发明人： Richard Melker
IPC分类号： A61B5/145 , A61B5/00 , A61B5/083 , A61B5/087 , A61B5/1455 , A61M16/00
CPC分类号： A61B5/0295 , A61B5/0205 , A61B5/02416 , A61B5/02427 , A61B5/0261 , A61B5/036 , A61B5/087 , A61B5/0873 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/4836 , A61B5/6819 , A61B5/682 , A61B5/6826 , A61B5/6829 , A61B5/7278 , A61B5/7282 , A61B2560/0276 , A61B2562/247 , A61M16/0003 , A61M16/0051 , A61M16/0057 , A61M16/021 , A61M16/0666 , A61M16/0672 , A61M16/08 , A61M16/20 , A61M2202/0208 , A61M2202/03 , A61M2205/3561 , A61M2205/3569 , A61M2210/0618 , A61M2210/0625 , A61M2210/0662 , A61M2230/06 , A61M2230/205 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/005 , A61M2202/0007
摘要： The present invention relates to a novel non-invasive perfusion/resistance status monitor system and methods of using the same, and more specifically, a vascular perfusion status monitor system receiving and processing signals from at least two pulse oximeter probes, where each of the at least two pulse oximeter probes are situated at advantageously different locations in a patient. Novel pulse oximeter probes are configured to be placed, respectively, across the lip or cheek, across the septum or nares of the nose, and on the tongue. These probes are fabricated to provide signals to estimate arterial oxygen saturation. Conventional oximeter probes also can be configured to function according to the novel methods of determining differences in peripheral blood flow and/or resistance described herein.
摘要翻译：本发明涉及一种新颖的非侵入性灌注/阻力状态监测系统及其使用方法，更具体地说，涉及一种血管灌注状态监测系统，其接收和处理来自至少两个脉搏血氧计探针的信号，其中每个至少两个脉搏血氧计探针位于病人有利的不同位置。新型脉搏血氧计探针被配置成分别穿过唇部或脸颊，穿过鼻子的隔膜或鼻孔以及舌头。制造这些探针以提供信号以估计动脉血氧饱和度。传统的血氧计探针也可以被配置为根据确定本文所述的外周血流量和/或电阻差异的新颖方法起作用。

24. 发明授权

US5599303A IV administration apparatus 失效
标题翻译： IV管理装置
公开(公告)号：US5599303A
公开(公告)日：1997-02-04
申请号：US344829
申请日：1994-11-21
申请人： Richard Melker , Eric J. Hulsman , Brad D. Wellington
发明人： Richard Melker , Eric J. Hulsman , Brad D. Wellington
IPC分类号： A61M5/168 , A61M5/14
CPC分类号： A61M5/16886
摘要： The subject invention is a novel apparatus for the administration of intravenous fluids. The invention is particularly well suited for accurately and efficiently administering intravenous fluids over a wide range of flow rates. Disclosed is an intravenous fluid administration apparatus having at lease one flow line capable of administering fluid at high flow rates and comprising an airless, dripless, fluid monitoring chamber. A preferred embodiment comprises a main flow line which diverges into at least two flow limbs, where one flow limb is a low-flow limb and another flow limb is a high-flow limb, each having separate flow indicators, and with the flow limbs typically converging into a common tube for fluid delivery to the patient. The subject invention also discloses a novel flow meter, which is particularly well suited for measuring and indicating flow rates over a wide range, without the introduction of air bubbles into the fluid flow being measured. The novel flow meter of the subject invention comprises an elastic displaceable member in a housing, whereby the relative position of the displaceable member, as effected by the amount of force exerted on the displaceable member by the fluid being measured, indicates the flow rate of the fluid.
摘要翻译：本发明是用于给予静脉注射液的新型装置。本发明特别适用于在宽范围的流速下准确和有效地施用静脉内流体。公开了一种具有至少一个能够以高流速施用流体并且包括无空气，无渗透的流体监测室的流动管线的静脉内流体给药装置。优选实施例包括主流线，其分叉成至少两个流动臂，其中一个流动臂是低流量肢体，另一个流动肢体是高流动肢体，每个流动肢体具有单独的流动指示器，并且通常具有流动肢体会聚到用于流体递送到患者的普通管中。本发明还公开了一种新颖的流量计，其特别适用于在宽范围内测量和指示流量，而不将气泡引入被测量的流体流中。本发明的新型流量计包括在壳体中的弹性可移动构件，由可动构件的相对位置，由所测量的流体施加在可移动构件上的力的影响，表示流量流体。

25. 发明授权

US07178519B2 Intubation tube placement assessment device 失效
标题翻译：插管管置放评估装置
公开(公告)号：US07178519B2
公开(公告)日：2007-02-20
申请号：US10301501
申请日：2002-11-21
申请人： Richard Melker , Dietrich Gravenstein , Andrea Gabrielli
发明人： Richard Melker , Dietrich Gravenstein , Andrea Gabrielli
IPC分类号： A61M16/00
CPC分类号： A61M16/0488 , A61M2016/0413 , A61M2230/432
摘要： A novel connection device, and method for its use, for connecting a volume displacement detection device and a gas composition detection device in line with an intubation tube is disclosed. The connection device allows a user to combine two systems commonly employed by medical personnel to assess the location of an intubation tube placed into a patient. The two systems have alternate means of assessing the location of an intubation tube in a patient and therefore, when combined into a single unit via the connection device, improve the accuracy of placing a tube in a desired location while reducing or eliminating complications associated with misplacement. A kit comprising components that may be assembled to provide a device for assessing the proper placement of an intubation tube in a patient is also disclosed. The kit may be used in any environment, but is particularly well suited for emergency, pre-hospital settings requiring intubation where quick assembly of the components is essential.
摘要翻译：公开了一种新颖的连接装置及其使用方法，用于连接体积位移检测装置和气体成分检测装置与插管一致。连接装置允许用户组合医疗人员通常使用的两个系统来评估放置在患者体内的插管的位置。两个系统具有评估插管在患者中的位置的替代方式，因此当通过连接装置组合成单个单元时，提高将管放置在所需位置的精度，同时减少或消除与错位相关的并发症。还公开了一种试剂盒，其包括可以组装以提供用于评估插管在患者体内的正确放置的装置的组件。该套件可以在任何环境中使用，但特别适用于紧急情况下，需要插管的紧急情况，需要快速组装组件是必需的。

26. 发明授权

US6115523A Plastic optical fiber airway imaging system 失效
标题翻译：塑料光纤气道成像系统
公开(公告)号：US6115523A
公开(公告)日：2000-09-05
申请号：US725779
申请日：1996-10-04
申请人： Won Young Choi , Dietrich Gravenstein , Samsun Lampotang , Richard Melker , James K. Walker
发明人： Won Young Choi , Dietrich Gravenstein , Samsun Lampotang , Richard Melker , James K. Walker
IPC分类号： A61B1/04 , A61B1/267 , A61B1/273 , G02B6/06
CPC分类号： A61B1/2676 , A61B1/0017 , A61B1/07 , A61B1/042
摘要： The subject invention pertains to a system for imaging the human airway having highly advantageous optical and physical characteristics. In a specific embodiment, the human airway can be imaged during the intubation procedure. The excellent characteristics of the imaging system of the subject invention result, in part, from the use of plastic optic fibers. Plastic fibers are more robust than the glass optical fibers used in currently available imaging systems, and are therefore capable of being bent and/or twisted with less concern of breakage. In addition, the lower costs of plastic fibers enables scopes of the subject invention, in a specific embodiment, to be manufactured for single patient use thereby eliminating the requirement for cleaning, special care, the maintenance of expensive inventory, and most importantly eliminating the opportunity for cross contamination between patients. A further aspect of the subject invention concerns a novel sheath which covers the portion of the imaging system which enters the patient. In this case, the sheath and its optional associated fiber optic illumination is disposable after each use.
摘要翻译：本发明涉及一种用于对具有非常有利的光学和物理特性的人气道成像的系统。在一个具体实施例中，人气道可以在插管过程中成像。本发明的成像系统的优异特征部分地导致使用塑料光纤。塑料纤维比当前可用的成像系统中使用的玻璃光纤更坚固，因此能够在较少的断裂的情况下弯曲和/或扭曲。此外，由于塑料纤维的成本较低，在一个具体实施例中，本发明的范围能够为单个患者使用而制造，从而消除了对清洁，特别护理，维护昂贵库存的要求，最重要的是消除了机会用于患者之间的交叉污染。本发明的另一方面涉及一种新颖的护套，其覆盖进入患者的成像系统的部分。在这种情况下，护套和其可选的相关联的光纤照明在每次使用之后是一次性的。

27. 发明授权

US5997891A Materials and methods utilizing a temporary visual indicator 失效
公开(公告)号：US5997891A
公开(公告)日：1999-12-07
申请号：US135768
申请日：1998-08-18
申请人： Ronnie S. Fuerst , Richard Melker , Christopher D. Batich
发明人： Ronnie S. Fuerst , Richard Melker , Christopher D. Batich
IPC分类号： A61K6/00 , A61K8/04 , A61K8/49 , A61K31/34 , A61Q17/04 , C09D7/00 , C11D3/40 , G01N31/22 , A61K7/00 , A61K7/42
CPC分类号： G01N31/221 , A61K6/0017 , A61K6/0058 , A61K8/046 , A61K8/4973 , A61Q17/04 , C09D7/00 , C11D3/40 , A61K2800/45 , Y10T428/13 , Y10T428/1352 , Y10T428/1397 , Y10T428/249995 , Y10T428/249997
摘要： This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.

28. 发明授权

US5837645A Materials and methods utilizing a temporary visual indicator 失效
公开(公告)号：US5837645A
公开(公告)日：1998-11-17
申请号：US674069
申请日：1996-07-01
申请人： Ronnie S. Fuerst , Richard Melker , Christopher D. Batich
发明人： Ronnie S. Fuerst , Richard Melker , Christopher D. Batich
IPC分类号： A61K6/00 , A61K8/04 , A61K8/49 , A61K31/34 , A61Q17/04 , C09D7/00 , C11D3/40 , G01N31/22 , B41M5/00 , A61K7/42 , B32B1/06
CPC分类号： G01N31/221 , A61K6/0017 , A61K6/0058 , A61K8/046 , A61K8/4973 , A61Q17/04 , C09D7/00 , C11D3/40 , A61K2800/45 , Y10T428/13 , Y10T428/1352 , Y10T428/1397 , Y10T428/249995 , Y10T428/249997
摘要： This invention relates to novel compositions containing temporary visual indicators and methods for using these compositions. Specifically, this invention relates to a sunscreen composition containing an indicator that is visible when the substance is applied to the skin, but becomes invisible shortly after application. The continued presence of the indicator allows the indicator to be reactivated temporarily to the visible form so that a user can verify the presence of the sunscreen. The visible indicator ensures that the sunscreen is applied evenly and completely to the area to be protected, but becomes invisible so as not to interfere with the action of the sunscreen or discolor the skin.

29. 发明申请

US20150048940A1 HAND HYGIENE COMPLICANCE CONFIRMATION SYSTEM 有权
标题翻译：手卫生合约确认系统
公开(公告)号：US20150048940A1
公开(公告)日：2015-02-19
申请号：US14234164
申请日：2012-08-17
申请人： Sam Keown , Mark Klusty , Eric Laster , Richard Melker , Henry Wohltjen , Ronald Youngblood
发明人： Sam Keown , Mark Klusty , Eric Laster , Richard Melker , Henry Wohltjen , Ronald Youngblood
IPC分类号： G08B21/24
CPC分类号： G08B21/245 , G06F19/00 , G09B19/0076 , G16H10/40 , G16H40/20
摘要： A Hand Hygiene Compliance Confirmation System (HHCCS) is disclosed for confirmation of compliance with Hand Hygiene Compliance Procedures (HHCPs) with minimized Response Time (RT) delay.
摘要翻译：公开了手卫生合规确认系统（HHCCS），以确保符合手卫生合规程序（HHCP），并以最小的响应时间（RT）延迟。

30. 发明申请

US20070027375A1 OPTIMIZED GAS SUPPLY USING PHOTOPLETHYSMOGRAPHY 有权
标题翻译：优化的气体供应使用光电子学
公开(公告)号：US20070027375A1
公开(公告)日：2007-02-01
申请号：US11535295
申请日：2006-09-26
申请人： Richard Melker , Brian Fuehrlein
发明人： Richard Melker , Brian Fuehrlein
IPC分类号： A61B5/00 , A61M16/00
CPC分类号： A61B5/0295 , A61B5/0205 , A61B5/02416 , A61B5/02427 , A61B5/0261 , A61B5/036 , A61B5/087 , A61B5/0873 , A61B5/14551 , A61B5/14552 , A61B5/4818 , A61B5/4836 , A61B5/6819 , A61B5/682 , A61B5/6826 , A61B5/6829 , A61B5/7278 , A61B5/7282 , A61B2560/0276 , A61B2562/247 , A61M16/0003 , A61M16/0051 , A61M16/0057 , A61M16/021 , A61M16/0666 , A61M16/0672 , A61M16/08 , A61M16/20 , A61M2202/0208 , A61M2202/03 , A61M2205/3561 , A61M2205/3569 , A61M2210/0618 , A61M2210/0625 , A61M2210/0662 , A61M2230/06 , A61M2230/205 , A61M2230/30 , A61M2230/42 , A61M2230/432 , A61M2230/005 , A61M2202/0007
摘要： The present invention relates to optimized gas supply utilizing photoplethysmography. Flow rate, pressure or amount of gas is adjusted as a function of blood oxygen saturation data, photoplethysmography signals, or both, obtained from the pulse oximeter probe.
摘要翻译：本发明涉及利用光电容积描记术优化的气体供应。流量，压力或气体量根据从脉搏血氧计探头得到的血氧饱和度数据，光谱体积描记信号或二者的函数进行调节。

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