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21. 发明申请

US20110245715A1 BIOPSY PROBE HAVING A TISSUE SPECIMEN COLLECTOR 审中-公开
标题翻译：具有组织样本收集器的生物探测器
公开(公告)号：US20110245715A1
公开(公告)日：2011-10-06
申请号：US13159675
申请日：2011-06-14
申请人： Richard L. Quick , Martin V. Shabaz , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Richard L. Quick , Martin V. Shabaz , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/02
CPC分类号： A61B17/32002 , A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473
摘要： A tissue specimen collector includes a collector housing defining an interior, and has a proximal opening and a distal port opposite the proximal opening. The distal port is configured to receive a proximal end of a tubular elongated member of a biopsy probe such that the proximal end can extend into the interior. A tray is releasably attached to the collector housing at the proximal opening. The tray includes a grated portion configured to extend through the proximal opening of the collector housing toward the distal port and into the interior to separate the collector housing to define a tissue chamber and a vacuum chamber, such that a tissue discharge port of the tubular elongated member is able to be positioned in the tissue chamber above the grated portion. The grated portion has a plurality of holes to facilitate fluid communication between the tissue chamber and the vacuum chamber.
摘要翻译：组织样本收集器包括限定内部的收集器壳体，并且具有近端开口和与近端开口相对的远端端口。远侧端口构造成容纳活检探针的管状细长构件的近端，使得近端可以延伸到内部。托盘在近端开口处可拆卸地附接到收集器壳体。托盘包括被配置成延伸穿过收集器壳体的近侧开口朝向远端端口并进入内部的碎屑部分，以分离收集器壳体以限定组织室和真空室，使得管状伸长的组织排出口构件能够被定位在磨碎部分上方的组织室中。磨碎部分具有多个孔，以促进组织室和真空室之间的流体连通。

22. 发明授权

US07819819B2 Biopsy device with inner cutting member 有权
标题翻译：内切割活检装置
公开(公告)号：US07819819B2
公开(公告)日：2010-10-26
申请号：US10642406
申请日：2003-08-15
申请人： Richard L. Quick , Frank R. Louw , Paul Lubock , Martin V. Shabaz
发明人： Richard L. Quick , Frank R. Louw , Paul Lubock , Martin V. Shabaz
IPC分类号： A61B10/00
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B90/39 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811 , A61B2090/309 , B23Q17/2404 , F21V33/0068
摘要： The invention is directed to devices and methods for separating and collecting a tissue specimen from a patient's target site. The device includes a probe member with a penetrating distal tip and a tissue receiving aperture, and a tissue cutting member which is rotatable disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture. The longitudinal edges of the aperture are preferably sharpened to engage the cutting edges of the tissue cutting member. Vacuum may be provided in the inner lumen of the cutting member to transport tissue therethrough. Rotation, rotational oscillation and/or longitudinal reciprocation of the tissue cutting member is effective to separate a tissue specimen from surrounding tissue. An accessing cannula having an tissue receiving aperture may be concentrically disposed within the probe member and about the tissue cutting member. The tissue cutting edge of the tissue cutting member preferably is longitudinally oriented and may have a cutting angle less than 90° with respect to the longitudinal axis of the tissue cutting member.
摘要翻译：本发明涉及用于从患者的目标部位分离和收集组织标本的装置和方法。该装置包括具有穿透性远侧末端和组织接收孔的探针构件，以及组织切割构件，该组织切割构件可旋转地设置在探针构件内，以通过孔切割被拉入装置内部的组织样本。孔的纵向边缘优选地被锐化以接合组织切割构件的切割边缘。可以在切割构件的内腔中设置真空以将组织输送通过其中。组织切割构件的旋转，旋转振动和/或纵向往复运动有效地将组织标本与周围组织分开。具有组织接收孔的进入套管可以同心地设置在探针构件内并且围绕组织切割构件。组织切割构件的组织切割边缘优选地纵向定向并且可以具有相对于组织切割构件的纵向轴线小于90°的切割角度。

23. 发明申请

US20090204021A1 Apparatus and method for accessing a body site 审中-公开
标题翻译：用于访问身体部位的装置和方法
公开(公告)号：US20090204021A1
公开(公告)日：2009-08-13
申请号：US12322749
申请日：2009-02-06
申请人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason Safabash
发明人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason Safabash
IPC分类号： A61B10/02 , A61B17/32
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/32053 , A61B17/3417 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473 , A61B2017/3405
摘要： A device to access a desired tissue site within a patient's body and separate a tissue specimen from the tissue site. The device includes a probe member having a tissue penetrating distal tip having a plurality of concaved surfaces which form curved cutting edges at the intersection of adjacent concave surfaces. The probe member has an inner lumen which when subjected to a vacuum, secures tissue for the specimen to the surface of a distal tubular section of the probe which may be off-set from a central longitudinal axis. A circular tissue-cutting blade is configured to move longitudinally to sever a tissue specimen from tissue secured to the surface of the distal tubular section by the application of a vacuum to the inner lumen of the probe.
摘要翻译：一种用于访问患者体内所需组织部位并从组织部位分离组织标本的装置。该装置包括具有组织穿透远侧末端的探针构件，该组织穿透远侧末端具有多个凹面，其在相邻凹面的交叉处形成弯曲的切割边缘。探针构件具有内腔，当经受真空时，将内窥镜的组织固定在探针的远侧管状部分的表面上，该表面可以从中心纵向轴线偏离。圆形组织切割刀片构造成纵向移动以通过向探针的内腔施加真空而将组织标本从组织固定到远端管状部分的表面。

24. 发明申请

US20090137928A1 Biopsy device with fluid delivery to tissue specimens 有权
标题翻译：活组织检查装置，液体输送到组织标本
公开(公告)号：US20090137928A1
公开(公告)日：2009-05-28
申请号：US12290961
申请日：2008-11-05
申请人： Richard L. Quick , Martin V. Shabaz , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Richard L. Quick , Martin V. Shabaz , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/00
CPC分类号： A61B17/32002 , A61B10/0275 , A61B10/0283 , A61B2010/0208 , A61B2010/0225 , A61B2017/00473
摘要： The invention is directed to a system and method for separating and collecting one or more tissue specimens from a target site within a patient and flushing the specimen to remove blood, debris and the like before the specimen is removed from the biopsy device. The flow of flushing fluid to the tissue collector is preferably controlled to coincide with delivery of one or more specimens to the collecting tray or basket of the device or after the receipt of the specimen within the tissue collector to ensure that the fluid is applied to a fresh specimen. The tissue tray or basket within the tissue collector has an open or foraminous portion to facilitate removal of fluid, such as the applied fluid and blood, and other debris from the tissue specimens on the tray. Vacuum is provided within the tissue collector, preferably under the tray to remove fluid and debris from the collector interior.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集一个或多个组织样本的系统和方法，并且在从活检装置移除样本之前冲洗样本以除去血液，碎屑等。冲洗流体到组织收集器的流动优选地被控制以与一个或多个样品递送到装置的收集盘或篮子之间或者在组织收集器内接收到样本之后确保将流体施加到新鲜标本。组织收集器内的纸巾托盘或篮子具有开放或有孔的部分，以有助于从托盘上的组织标本中去除流体，例如所施加的流体和血液以及其它碎屑。在组织收集器内提供真空，优选在托盘下面，以从收集器内部去除流体和碎屑。

25. 发明申请

US20080319342A1 Biopsy device with selectable tissue receiving aperture orientation and site illumination 审中-公开
标题翻译：活组织检查装置，可选择组织接收孔径取向和局部照明
公开(公告)号：US20080319342A1
公开(公告)日：2008-12-25
申请号：US12229553
申请日：2008-08-25
申请人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
发明人： Martin V. Shabaz , Richard L. Quick , Frank R. Louw , Paul Lubock , Jason H. Safabash
IPC分类号： A61B10/02
CPC分类号： A61B10/0266 , A61B10/02 , A61B10/0233 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B90/39 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811 , A61B2090/309 , A61M1/0058 , B23Q17/2404 , F21V33/0068
摘要： The invention is directed to a system and device for separating and collecting a tissue specimen from a target site within a patient. The device includes a probe component with an elongated tubular section, a penetrating distal tip and a tissue receiving aperture in the distal end of the tubular section proximal to the distal tip, and a tissue cutting member which is slidably disposed within the probe member to cut a tissue specimen drawn into the interior of the device through the aperture by applying a vacuum to the inner lumen of the tissue cutting member. The device also has a driver component to which the probe component is releasably secured. The driver has a drive member for adjusting the orientation of the tubular section and thus the aperture therein and one or more drive members for moving the tissue cutting member within the tubular section to sever a tissue specimen from tissue extending into the interior of the tubular section through the aperture. The motion imparted to the tissue cutter is at least longitudinal and preferably is also oscillation and/or rotational to effectively separate a tissue specimen from tissue extending through the aperture in the tubular section.
摘要翻译：本发明涉及一种用于从患者内的目标部位分离和收集组织标本的系统和装置。该装置包括具有细长管状部分的探针部件，穿透远侧末端和在远端顶端的管状部分的远端中的组织接收孔，以及组织切割构件，其可滑动地设置在探针构件内以切割组织样本通过向组织切割构件的内腔施加真空而通过孔被拉入装置的内部。该装置还具有驱动器部件，探针组件可释放地固定到该部件上。驱动器具有用于调节管状部分的方向并因此调节其中的孔的驱动构件和一个或多个驱动构件，用于移动管状区段内的组织切割构件以将组织样本从延伸到管状部分内部的组织切断通过光圈。赋予组织切割器的运动至少是纵向的，并且优选也是振动和/或旋转以有效地将组织样本与延伸穿过管状部分中的孔的组织分离。

26. 发明申请

US20080287828A1 Biopsy anchor device with cutter 审中-公开
标题翻译：带切割器的活检锚固装置
公开(公告)号：US20080287828A1
公开(公告)日：2008-11-20
申请号：US12148818
申请日：2008-04-23
申请人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
发明人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
IPC分类号： A61B10/02 , A61B18/18
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1246 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： A device for accessing and for isolating a desired site within a patient's body, and for obtaining a body of tissue from a patient at the site that includes an electrosurgical cutting electrode near the distal tip of a shaft, an anchoring mechanism and an electrosurgical side-cutting device. Methods are provided for accessing a target site within a patient's body, anchoring a body of tissue at the site, and isolating the body of tissue, at the site. The method may be performed for a surgical biopsy or lumpectomy at the target site within a patient's body.
摘要翻译：一种用于访问和隔离患者体内所需位置的装置，并且用于从包括在轴的远侧末端附近的电外科切割电极的位置处获得来自患者的组织体，锚定机构和电外科侧面装置，切割装置。提供了用于访问患者身体内的目标部位，将身体的身体固定在现场，以及在现场隔离组织体的方法。该方法可以在患者体内的目标部位进行外科活检或乳房切除术。

27. 发明授权

US07377902B2 Biopsy anchor device with cutter 有权
标题翻译：带切割器的活检锚固装置
公开(公告)号：US07377902B2
公开(公告)日：2008-05-27
申请号：US10056453
申请日：2002-01-23
申请人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
发明人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
IPC分类号： A61B10/00 , A61B18/18 , A61B17/32 , A61B17/14
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1246 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： A device for accessing and for isolating a desired site within a patient's body, and for obtaining a body of tissue from a patient at the site that includes an electrosurgical cutting electrode near the distal tip of a shaft, an anchoring mechanism and an electrosurgical side-cutting device. Methods are provided for accessing a target site within a patient's body, anchoring a body of tissue at the site, and isolating the body of tissue at the site. The method may be performed for a surgical biopsy or lumpectomy at the target site within a patient's body.
摘要翻译：一种用于访问和隔离患者体内所需位置的装置，并且用于从包括在轴的远侧末端附近的电外科切割电极的位置处获得来自患者的组织体，锚定机构和电外科侧面装置，切割装置。提供了用于访问患者身体内的目标部位的方法，将身体的身体固定在部位，以及分离现场的组织体。该方法可以在患者体内的目标部位进行外科活检或乳房切除术。

28. 发明授权

US06540695B1 Biopsy anchor device with cutter 有权
标题翻译：带切割器的活检锚固装置
公开(公告)号：US06540695B1
公开(公告)日：2003-04-01
申请号：US09753529
申请日：2000-12-28
申请人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
发明人： Fred Burbank , Richard L. Quick , Martin V. Shabaz , Paul Lubock , Michael L. Jones
IPC分类号： A61B500
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/0218 , A61B17/282 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B17/3439 , A61B18/14 , A61B18/1477 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/02 , A61B90/37 , A61B90/39 , A61B2010/0208 , A61B2017/320064 , A61B2017/320733 , A61B2017/3484 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00273 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1246 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908
摘要： A device for accessing and for isolating a desired site within a patient's body, and for obtaining a body of tissue from a patient at the site that includes an electrosurgical cutting electrode near the distal tip of a shaft, an anchoring mechanism and an electrosurgical side-cutting device. Methods are provided for accessing a target site within a patient's body, anchoring a body of tissue at the site, and isolating the body of tissue at the site. The method may be performed for a surgical biopsy or lumpectomy at the target site within a patient's body.
摘要翻译：一种用于访问和隔离患者体内所需位置的装置，并且用于从包括在轴的远侧末端附近的电外科切割电极的位置处获得来自患者的组织体，锚定机构和电外科侧面装置，切割装置。提供了用于访问患者身体内的目标部位的方法，将身体的身体固定在部位，以及分离现场的组织体。该方法可以在患者体内的目标部位进行外科活检或乳房切除术。

29. 发明授权

US07189206B2 Biopsy device with inner cutter 有权
标题翻译：内切刀活检装置
公开(公告)号：US07189206B2
公开(公告)日：2007-03-13
申请号：US10374915
申请日：2003-02-24
申请人： Richard L. Quick , Frank Louw , Paul Lubock , Martin V. Shabaz
发明人： Richard L. Quick , Frank Louw , Paul Lubock , Martin V. Shabaz
IPC分类号： A61B10/00
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32002 , A61B17/3417 , A61B90/30 , A61B90/39 , A61B2010/0208 , A61B2010/0225 , A61B2017/0046 , A61B2017/00473 , A61B2017/3405 , A61B2017/3454 , A61B2090/0811 , A61B2090/309 , B23Q17/2404 , F21V33/0068
摘要： The invention is directed to devices and methods for accessing a desired target site within a patient's body and for separating and collecting a tissue specimen from the target site. The device includes a probe member or cannula with a penetrating distal tip, and a tissue cutting member which is disposed within the probe member to cut a tissue specimen from supporting tissue at the biopsy site. This probe is releasably secured to a housing to provide a plurality of discrete orientations of the probe about its longitudinal axis. Vacuum may be provided to the inner lumen of the cutting member to transport tissue through the inner lumen thereof. Rotation (and optionally longitudinal reciprocation) of the tissue cutter is effective to separate a tissue specimen from surrounding tissue at the target site. Vacuum or fluid pressure may be used to move the specimen cut from the target site proximally within the inner lumen defined at least in part by the culling member for collection.
摘要翻译：本发明涉及用于访问患者体内期望的目标部位并用于从目标部位分离和收集组织标本的装置和方法。该装置包括具有穿透性远侧末端的探针构件或套管，以及组织切割构件，其设置在探针构件内以从活组织检查部位的支撑组织切割组织样本。该探针可释放地固定到壳体以提供探针围绕其纵向轴线的多个离散定向。可以向切割构件的内腔提供真空以将组织输送通过其内腔。组织切割器的旋转（和任选的纵向往复运动）有效地将组织标本与目标部位的周围组织分离。可以使用真空或流体压力将从目标位置切割的样本移动到内部腔内的至少一部分由剔除构件限定以用于收集的内腔。

30. 发明授权

US06712775B2 Tissue acquisition system and method of use 失效
标题翻译：组织采集系统及使用方法
公开(公告)号：US06712775B2
公开(公告)日：2004-03-30
申请号：US10202547
申请日：2002-07-23
申请人： Fred Burbank , Paul Lubock , Michael L. Jones , Martin V. Shabaz
发明人： Fred Burbank , Paul Lubock , Michael L. Jones , Martin V. Shabaz
IPC分类号： A61B1000
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2010/0225 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A tissue acquisition system includes radio frequency (RF) cutter loops which are extendable out a cannula to cut cylindrical tissue samples from a tissue of interest in a patient. The cannula includes inner and outer cannulae which are mutually rotatable and include cutouts through which the cutting loop can be rotated and longitudinally extended to perform the cuts. The tissue samples are then aspirated proximally through the cannula for collection.
摘要翻译：组织采集系统包括射频（RF）切割器回路，其可伸出套管以从病人的感兴趣的组织切割圆柱形组织样本。套管包括内部和外部套管，其可相互旋转并且包括切口，切割环可以通过切口旋转并纵向延伸以执行切割。然后将组织样品通过套管向近侧吸出以进行收集。

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