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21. 发明授权

US5944701A Self coiling catheter 失效
标题翻译：自卷盘导管
公开(公告)号：US5944701A
公开(公告)日：1999-08-31
申请号：US942588
申请日：1997-10-02
申请人： William R. Dubrul
发明人： William R. Dubrul
IPC分类号： A61M25/00 , A61M25/09
CPC分类号： A61M25/0021 , A61M25/09 , A61M2025/09066 , A61M2025/09083
摘要： Medical guidewires have coiled proximal ends which allow and facilitate management of guidewires during use in an operating room.
摘要翻译：医疗导丝线具有卷绕的近端，其允许并便于在手术室中使用期间引导线的管理。

22. 发明授权

US5540658A Transcervical uterine access and sealing device 失效
标题翻译：子宫颈进入和密封装置
公开(公告)号：US5540658A
公开(公告)日：1996-07-30
申请号：US266036
申请日：1994-06-27
申请人： Michael A. Evans , William R. Dubrul , Hen Lao
发明人： Michael A. Evans , William R. Dubrul , Hen Lao
IPC分类号： A61B18/12 , A61B17/34 , A61B17/42 , A61B18/00 , A61F7/12 , A61M29/00
CPC分类号： A61B17/42 , A61B18/00 , A61B2017/3486 , A61B2017/3492 , A61B2018/00101 , A61B2018/00166
摘要： A cervical access device includes a tubular body having a proximal end, a distal end, and a lumen extending therebetween. A first expansible occlusion member is disposed near the distal end of the tubular body, and a second occlusion member is proximally spaced apart from the first occlusion member. Together, the first and second occlusion members define a reduced diameter neck for receiving the cervical os. In an exemplary aspect, the first occlusion member includes an evertible cylindrical surface which assumes a conical configuration which diverges in the distal direction when actually compressed. The second occlusion member can also be provided with a conical configuration which diverges in the proximal direction so that the first and second occlusion members when brought together define a neck having opposed tapered walls. A catheter for providing thermal treatment to the uterus can be introduced through the cervical access device to perform thermal treatment on the uterus. The cervical access device provides a seal with the cervical os to help prevent heated thermally conductive medium introduced by the catheter from leaking around the cervical access device outwardly into the vagina.
摘要翻译：子宫颈进入装置包括具有近端，远端和在其间延伸的内腔的管状体。第一可膨胀闭塞构件设置在管状体的远端附近，并且第二闭塞构件与第一闭塞构件向近侧间隔开。一起，第一和第二闭塞构件限定用于接收宫颈口的缩径的颈部。在一个示例性方面，第一遮挡构件包括可翻转的圆柱形表面，其呈现出当实际压缩时在远端方向上分叉的锥形构造。第二遮挡构件还可以设置有在近端方向上分叉的锥形构造，使得第一和第二遮挡构件一起形成具有相对的锥形壁的颈部。可以通过子宫颈进入装置引入用于向子宫提供热治疗的导管，以对子宫进行热处理。子宫颈进入装置提供与子宫颈口的密封，以帮助防止由导管引入的加热的导热介质从颈部进入装置向外渗入阴道。

23. 发明授权

US5454790A Method and apparatus for catheterization access 失效
标题翻译：用于导管插入的方法和装置
公开(公告)号：US5454790A
公开(公告)日：1995-10-03
申请号：US240059
申请日：1994-05-09
申请人： William R. Dubrul
发明人： William R. Dubrul
IPC分类号： A61M25/00 , A61B17/34 , A61M25/01 , A61M25/04 , A61M25/06 , A61M29/00
CPC分类号： A61M25/0102 , A61M25/04 , A61M25/0668 , A61B17/3474
摘要： An apparatus and method for percutaneous placement of access tubes, such as feeding and drainage tubes, vascular catheters, and the like, comprises an elastic access tube in an internal stylet. The stylet is received within a central lumen of the access tube and is used to axially elongate the tube, resulting in a reduced diameter. In a first embodiment, the diameter of the access tube is reduced sufficiently so that it can be placed through a relatively narrow penetration and so that it will radially expand by an amount sufficient to cause a tight anchor and seal against the penetration when the stylet is removed. In a second embodiment, the stylet has a sharpened distal tip which extends beyond the distal end of the access tube when in its axially extended configuration. The sharpened tip allows self-introduction of the assembly of access tube and stylet. In a third embodiment, a distal portion of the access tube is covered with a lubricous sheath. The lubricous sheath facilitates use of the assembly in combination with a dilation member which is radially expanded when the assembly of access tube and stylet is introduced therethrough.
摘要翻译：用于经皮放置入口管（例如进食管和引流管，血管导管等）的装置和方法包括在内部探针中的弹性进入管。探针被容纳在入口管的中央管腔中，并且用于轴向地延长管，导致直径减小。在第一实施例中，进入管的直径被充分地减小，使得其可以通过相对窄的穿透被放置，并且使得其将径向扩张足够的量，以便当探针为删除。在第二实施例中，探针具有尖锐的远侧末端，其在其轴向延伸构造中延伸超过进入管的远端。锋利的尖端允许自引导入口管和探针的组件。在第三实施例中，入口管的远端部分被润滑护套覆盖。润滑护套有助于将组件与膨胀构件组合使用，当扩大构件通过其进入入口管和通路管的组件时，其膨胀。

24. 发明授权

US4798584A Self-sealing injection reservoir 失效
标题翻译：自密封注水池
公开(公告)号：US4798584A
公开(公告)日：1989-01-17
申请号：US167394
申请日：1988-03-14
申请人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
发明人： John C. Hancock , William R. Dubrul , Charles J. Heyler, III
IPC分类号： C08G73/10 , C08G73/12 , A61M25/00 , A61B19/00
CPC分类号： C08G73/1071 , C08G73/10 , C08G73/1014 , C08G73/1039 , C08G73/1064 , C08G73/1067 , C08G73/1075 , C08G73/122
摘要： An injection reservoir or button is disclosed which is adapted for implantation beneath the skin of human and animal patients in conjunction with tissue expanders and drug delivery devices. The injection reservoir includes a base and an exterior wall which define a chamber or liquid reservoir. A suitable duct connects the chamber with an expandable bag of the tissue expander. An elastic rubber member is affixed within the interior of the chamber in a configuration wherein its side abutting the chamber is in compression, thereby rendering the member self-sealing to punctures by a hypodermic needle. A metal guard plate is included within the interior of the chamber to guard the base against accidental puncture by an over-extended hypodermic needle.
摘要翻译：公开了一种注射储器或按钮，其适于与组织扩张器和药物递送装置一起在人和动物患者的皮肤下植入。注入储存器包括限定腔室或液体储存器的底座和外壁。合适的管道将腔室与组织扩张器的可膨胀袋连接。弹性橡胶构件以这样的构造固定在腔室内部，其中其邻接室的侧面处于压缩状态，从而使构件自密封地被皮下注射针穿刺。在室内部包括一个金属防护板，用于防止基座由一个过度延伸的皮下注射针引起的意外穿刺。

25. 发明授权

US07981132B2 Self-conforming surgical seal 失效
标题翻译：自我符合的手术密封
公开(公告)号：US07981132B2
公开(公告)日：2011-07-19
申请号：US11936893
申请日：2007-11-08
申请人： William R. Dubrul , Craig K. Tsuji , John E. Carlson
发明人： William R. Dubrul , Craig K. Tsuji , John E. Carlson
IPC分类号： A61B17/34 , A61B17/00
CPC分类号： A61B17/3439 , A61B17/00234 , A61B17/3431 , A61B17/3474 , A61B2017/00986 , A61B2017/3484 , A61B2090/0815 , A61F2/0063 , A61M25/0662 , A61M2025/0025
摘要： The present disclosure relates to surgical seal, or valve, of the type adapted to releasably receive a surgical object. The seal disclosed herein defines an aperture that is configured to maintain a substantially fluid-tight seal with the surgical object upon its insertion, and includes at least one cable member connected to the seal that facilitates maintenance of the substantially fluid-tight seal during subsequent lateral manipulation of the surgical object.
摘要翻译：本公开涉及适于可释放地接收手术对象的类型的手术密封件或阀。本文公开的密封件限定了孔，其构造成在其插入时保持与外科物体基本上不流体密封的密封，并且包括连接到密封件的至少一个缆索构件，其有助于在随后的侧面中维持基本上不透气的密封操纵手术对象。

26. 发明授权

US07524319B2 Particle-removing medical device and method 有权
公开(公告)号：US07524319B2
公开(公告)日：2009-04-28
申请号：US10866980
申请日：2004-06-14
申请人： William R. Dubrul
发明人： William R. Dubrul
IPC分类号： A61B17/24
CPC分类号： A61M25/104 , A61F2/90 , A61F2/958 , A61F2250/0067 , A61L29/16 , A61L2300/416 , A61M25/10 , A61M25/1011 , A61M2025/0057 , A61M2025/1052 , A61M2025/1081 , A61N1/306 , A61N1/327
摘要： A particle-removing medical device includes an outer, hollow tube having a tube distal end and a porous braided structure having a distal part and a proximal part. Structure, housed within the tube and having a distal end positioned distally of the tube distal end, is used to move the braided structure from a contracted condition to an expanded condition by moving the distal ends of the tube and the structure towards one another. The braided structure is constructed to inhibit particles from moving completely through the braided structure when in the expanded condition.

27. 发明授权

US06409742B1 Target tissue localization device and method 失效
标题翻译：靶组织定位装置及方法
公开(公告)号：US06409742B1
公开(公告)日：2002-06-25
申请号：US09678508
申请日：2000-10-02
申请人： Richard Eustis Fulton, III , William R. Dubrul
发明人： Richard Eustis Fulton, III , William R. Dubrul
IPC分类号： A61M2900
CPC分类号： A61M25/04 , A61B90/39 , A61B2090/3908
摘要： A target tissue localization device (28) has outer and inner members (30, 32) which are longitudinally movable relative to one another. An anchor (42) is secured to the outer and inner members and is movable from a radially-contracted configuration to a radially-expanded configuration. The anchor may be a tubular mesh anchor. The anchor may have a sufficiently large cross-sectional area when in the radially-expanded configuration to substantially eliminate inadvertent dislodgment of the anchor once radially-expanded. In use, the location of the target tissue (56) is determined and the distal end of the localization device is passed through the patient's skin (58) and to the target tissue to create a tissue track (60) between the patient's skin and the target tissue. The target tissue includes near and far sides (62, 64). The anchor element, located at the target tissue is expanded to an expanded configuration. The method the anchor element may be located on the far side of the target tissue. The localization device may be selected with an anchor which is palpable for relocation of the target tissue.
摘要翻译：目标组织定位装置（28）具有能够相对于彼此纵向移动的外部构件（30）和内部构件（32）。锚固件（42）固定到外部构件和内部构件，并且可以从径向缩小构型移动到径向扩张构型。锚可以是管状网锚。当处于径向展开的构型中时，锚具可以具有足够大的横截面面积，以基本上消除锚固件一旦径向膨胀的无意中的移动。在使用中，确定目标组织（56）的位置，并且定位装置的远端通过患者的皮肤（58）和目标组织，以在患者的皮肤和患者的皮肤之间产生组织轨迹（60）目标组织。目标组织包括近侧和远侧（62,64）。位于目标组织的锚定元件被扩展到扩展构型。锚定元件可以位于目标组织的远侧上的方法。定位装置可以用可触及目标组织重新定位的锚点来选择。

28. 发明授权

US06325812B1 Trocar system having expandable port 失效
标题翻译：具有可扩展端口的套管针系统
公开(公告)号：US06325812B1
公开(公告)日：2001-12-04
申请号：US09477227
申请日：2000-01-04
申请人： William R. Dubrul , Craig K. Tsuji , John E. Carlson
发明人： William R. Dubrul , Craig K. Tsuji , John E. Carlson
IPC分类号： A61B1734
CPC分类号： A61B17/3439 , A61B17/00234 , A61B17/3431 , A61B17/3474 , A61B2017/00986 , A61B2017/3484 , A61B2090/0815 , A61F2/0063 , A61M25/0662 , A61M2025/0025
摘要： An apparatus and method for forming and enlarging percutaneous penetrations comprises an elongate dilation member which receives an elongate expansion member in an axial lumen thereof. The dilation tube includes a tubular braid which usually comprises a mesh of non-elastic filaments which are radially expandable from a small diameter configuration to a large diameter configuration and which is optionally covered by a removable sheath. The dilation tube is percutaneously introduced to a target site within a patient's body, usually within the abdomen in a laparoscopic procedure. The sheath (if present) is then removed, and the tubular braid thereafter radially expanded by axial insertion of the expansion member through its lumen. The tubular braid is anchored by axial shortening of the mesh and remains in place to permit subsequent exchange of dilation members to provide for different diameter access lumens. Trocar valves may be removably attached to the proximal end of the expansion member to permit the apparatus to be used as a trocar system in laparoscopic procedures where the patient's abdomen has been insufflated. An anchoring means may optionally be provided at the distal end of the expansion member.
摘要翻译：用于形成和扩大经皮穿透的装置和方法包括在其轴向腔内容纳细长膨胀构件的细长扩张构件。膨胀管包括管状编织物，其通常包括非弹性细丝网，其可从小直径构型径向扩展为大直径构造，并且可选地被可移除护套覆盖。扩张管经腹腔镜手术经皮导入患者体内的目标部位，通常在腹部。然后去除护套（如果存在），然后管状编织物通过膨胀构件通过其内腔的轴向插入而径向膨胀。管状编织物通过网状物的轴向缩短而锚定并保持在适当位置，以允许随后更换膨胀构件以提供不同直径的入口腔。套管针阀可以可移除地附接到膨胀构件的近端，以允许该装置在腹腔镜手术中用作套管针系统，其中患者的腹部已被吹入。可以可选地在扩张构件的远端设置锚固装置。

29. 发明授权

US6080174A Trocar system having expandable port 失效
公开(公告)号：US6080174A
公开(公告)日：2000-06-27
申请号：US424696
申请日：1995-04-19
申请人： William R. Dubrul , Craig K. Tsuji
发明人： William R. Dubrul , Craig K. Tsuji
IPC分类号： A61B1/00 , A61B17/00 , A61B17/34 , A61B19/00 , A61F2/00 , A61M25/06
CPC分类号： A61B17/3439 , A61B17/00234 , A61B17/3431 , A61B17/3474 , A61B2017/00986 , A61B2017/3484 , A61B2090/0815 , A61F2/0063 , A61M2025/0025 , A61M25/0662
摘要： An apparatus and method for forming and enlarging percutaneous penetrations comprises an elongate dilation member which receives an elongate expansion member in an axial lumen thereof. The dilation tube includes a tubular braid which usually comprises a mesh of non-elastic filaments which are radially expandable from a small diameter configuration to a large diameter configuration and which is optionally covered by a removable sheath. The dilation tube is percutaneously introduced to a target site within a patient's body, usually within the abdomen in a laparoscopic procedure. The sheath (if present) is then removed, and the tubular braid thereafter radially expanded by axial insertion of the expansion member through its lumen. The tubular braid is anchored by axial shortening of the mesh and remains in place to permit subsequent exchange of dilation members to provide for different diameter access lumens. Trocar valves may be removably attached to the proximal end of the expansion member to permit the apparatus to be used as a trocar system in laparoscopic procedures where the patient's abdomen has been insufflated. An anchoring means may optionally be provided at the distal end of the expansion member.

30. 发明授权

US5836913A Device and method for accessing a body cavity 失效
标题翻译：用于访问体腔的装置和方法
公开(公告)号：US5836913A
公开(公告)日：1998-11-17
申请号：US850795
申请日：1997-05-02
申请人： Michael J. Orth , John E. Carlson , William R. Dubrul , Steven P. Masterson
发明人： Michael J. Orth , John E. Carlson , William R. Dubrul , Steven P. Masterson
IPC分类号： A61B17/34 , A61M37/00
CPC分类号： A61B17/3417 , A61B2017/3419 , A61B2017/3484 , A61B2017/3492
摘要： Devices and methods for providing access to a body cavity without substantial loss of inflation gas therein. The device comprises an access assembly 10 that may have a tubular member 12, at least one sleeve 16 coaxially disposed over the tubular member, a pneumostasis valve 13 attached to the tubular member, and an obturator 11 removably received in the tubular member. Sleeve 16 comprises expandable region 19 capable of forming an anchor 30 upon axial compression. A method to provide access using assembly 10 comprises insertion of the assembly 10 into the body cavity, expanding region 19, and insufflating the cavity with gas. Expandable region 19 on assembly 10 is axially compressed to form anchor 30 to seal against an interior wall of the body cavity. The method may further comprise either a second expanded anchor 50 or a non-expanding anchor 40 which clamps against an exterior wall of the body cavity to securely position and seal the access assembly 10.
摘要翻译：用于提供进入体腔的装置和方法，其中不会充分损失充气气体。该装置包括进入组件10，其可以具有管状构件12，同轴地设置在管状构件上的至少一个套筒16，附接到管状构件的止血阀13和可移除地容纳在管状构件中的闭塞件11。套筒16包括能够在轴向压缩时形成锚固件30的可扩张区域19。使用组件10提供接近的方法包括将组件10插入体腔，扩张区域19中，并用气体吹入空腔。组件10上的可膨胀区域19被轴向压缩以形成锚固件30以密封体腔的内壁。该方法可以进一步包括第二膨胀锚固件50或不扩展锚固件40，其夹紧在体腔的外壁上以牢固地定位和密封进入组件10。

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