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21. 发明授权

US08900866B2 Method for forming nerve graft 有权
标题翻译：形成神经移植物的方法
公开(公告)号：US08900866B2
公开(公告)日：2014-12-02
申请号：US13349577
申请日：2012-01-13
申请人： Chen Feng , Li Fan , Wen-Mei Zhao
发明人： Chen Feng , Li Fan , Wen-Mei Zhao
IPC分类号： C12N5/00 , C12N5/02 , A61L27/08 , A61L27/34
CPC分类号： A61L27/34 , A61L27/08 , A61L2400/12 , A61L2430/32
摘要： A method for forming a nerve graft includes the following steps. A carbon nanotube structure is provided. A hydrophilic layer is formed on a surface of the carbon nanotube structure. The hydrophilic layer is polarized to form a polar surface on the hydrophilic layer. A number of neurons are formed on the polar surface of the hydrophilic layer to form a nerve network. The neurons connect with each other.
摘要翻译：形成神经移植物的方法包括以下步骤。提供碳纳米管结构。在碳纳米管结构的表面上形成亲水层。亲水层被极化以在亲水层上形成极性表面。在亲水层的极性表面上形成许多神经元以形成神经网络。神经元相互连接。

22. 发明授权

US09370607B2 Nerve graft 有权
标题翻译：神经移植
公开(公告)号：US09370607B2
公开(公告)日：2016-06-21
申请号：US13349582
申请日：2012-01-13
申请人： Chen Feng , Li Fan , Wen-Mei Zhao
发明人： Chen Feng , Li Fan , Wen-Mei Zhao
IPC分类号： A61F2/02 , A61L27/38 , A61L27/42
CPC分类号： A61L27/383 , A61L27/422 , A61L2400/12 , A61L2430/32
摘要： A nerve graft includes a carbon nanotube structure, a hydrophilic layer, and a nerve network. The hydrophilic layer having a polar surface is located on a surface of the carbon nanotube structure. The nerve network positioned on the polar surface of the hydrophilic layer includes a number of neurons connecting with each other. The nerve network has a polarity. The polar surface of the hydrophilic layer has a polarity attracted to the polarity of the nerve network.
摘要翻译：神经移植物包括碳纳米管结构，亲水层和神经网络。具有极性表面的亲水层位于碳纳米管结构的表面上。位于亲水层的极性表面上的神经网络包括彼此连接的多个神经元。神经网络具有极性。亲水层的极性表面具有吸引到神经网络极性的极性。

23. 发明授权

US09334474B2 Method for manufacturing culture medium comprising carbon nanotubes and growing cells thereon 有权
标题翻译：用于制造包含碳纳米管和生长细胞的培养基的方法
公开(公告)号：US09334474B2
公开(公告)日：2016-05-10
申请号：US13450648
申请日：2012-04-19
申请人： Li Fan , Chen Feng , Wen-Mei Zhao
发明人： Li Fan , Chen Feng , Wen-Mei Zhao
IPC分类号： C12N5/071 , C12N5/00 , B82Y5/00
CPC分类号： C12N5/0068 , B82Y5/00 , C12N2533/10
摘要： A culture medium for growing at least one kind of cells is provided. The culture medium includes a carbon nanotube structure and a cell adhesion layer. The cell adhesion layer covers one surface of the carbon nanotube structure. The at least one kind of cells grows on the cell adhesion layer. In addition, a method for manufacturing a culture medium for growing at least one kind of cells is also provided.
摘要翻译：提供了用于生长至少一种细胞的培养基。培养基包括碳纳米管结构和细胞粘附层。细胞粘附层覆盖碳纳米管结构的一个表面。至少一种细胞在细胞粘附层上生长。此外，还提供了用于生长至少一种细胞的培养基的制造方法。

24. 发明授权

US09295759B2 Nerve graft 有权
标题翻译：神经移植
公开(公告)号：US09295759B2
公开(公告)日：2016-03-29
申请号：US12981573
申请日：2010-12-30
申请人： Li Fan , Chen Feng , Wen-Mei Zhao
发明人： Li Fan , Chen Feng , Wen-Mei Zhao
IPC分类号： A61F2/02 , A61L27/36 , A61L27/34
CPC分类号： A61L27/3675 , A61L27/34 , A61L2400/12 , A61L2430/32
摘要： A nerve graft includes a carbon nanotube film structure, a protein layer, and a nerve network. The protein layer is located on a surface of the carbon nanotube film structure. The nerve network is positioned on a surface of the protein layer and far away from the carbon nanotube film structure.
摘要翻译：神经移植物包括碳纳米管膜结构，蛋白质层和神经网络。蛋白质层位于碳纳米管膜结构的表面上。神经网络位于蛋白质层的表面并且远离碳纳米管膜结构。

25. 发明授权

US08796024B2 Method for culturing neural cells using culture medium comprising carbon nanotube wires 有权
标题翻译：使用包含碳纳米管线的培养基培养神经细胞的方法
公开(公告)号：US08796024B2
公开(公告)日：2014-08-05
申请号：US13563953
申请日：2012-08-01
申请人： Li Fan , Chen Feng , Wen-Mei Zhao
发明人： Li Fan , Chen Feng , Wen-Mei Zhao
IPC分类号： C12N5/079
CPC分类号： C12N5/0619 , C12N2533/10
摘要： A method for culturing neural cells using a culture medium is provided. Each neural cell includes a neural cell body and at least one neurite branched from the neural cell body. The culture medium includes a substrate and a carbon nanotube structure located on the substrate. A surface of the carbon nanotube structure is polarized to form a polar surface. The neural cells are cultured on the polar surface to grow neurites along the carbon nanotube wires. The carbon nanotube structure includes a number of carbon nanotube wires spaced apart from each other. A distance between adjacent carbon nanotube wires is greater than or equal to a diameter of the neural cell body.
摘要翻译：提供了使用培养基培养神经细胞的方法。每个神经细胞包括神经细胞体和从神经细胞体分支的至少一个神经突。培养基包括基材和位于基材上的碳纳米管结构。碳纳米管结构的表面被极化以形成极性表面。将神经细胞在极性表面培养，沿着碳纳米管线生长神经突。碳纳米管结构包括彼此间隔开的多个碳纳米管线。相邻碳纳米管线之间的距离大于或等于神经细胞体的直径。

26. 发明授权

US09867901B2 Method for making nerve graft 有权
公开(公告)号：US09867901B2
公开(公告)日：2018-01-16
申请号：US12981572
申请日：2010-12-30
申请人： Chen Feng , Li Fan , Wen-Mei Zhao
发明人： Chen Feng , Li Fan , Wen-Mei Zhao
IPC分类号： C12N5/079 , A61L27/08 , A61L27/30 , A61L27/34 , A61L27/38
CPC分类号： A61L27/08 , A61L27/303 , A61L27/34 , A61L27/383 , A61L27/3878 , A61L2400/12 , A61L2420/04 , A61L2430/32
摘要： A method for making a nerve graft includes the following steps. A culture layer including a lyophobic substrate, a carbon nanotube film structure, and a protein layer is provided. The carbon nanotube film structure is sandwiched between the lyophobic substrate and the protein layer. A number of nerve cells are seeded on a surface of the protein layer away from the lyophobic substrate. The nerve cells are cultured until a number of neurites branch from the nerve cells and are connected between the nerve cells.

27. 发明授权

US09433703B2 Neural graft 有权
标题翻译：神经移植
公开(公告)号：US09433703B2
公开(公告)日：2016-09-06
申请号：US13563980
申请日：2012-08-01
申请人： Li Fan , Chen Feng , Wen-Mei Zhao
发明人： Li Fan , Chen Feng , Wen-Mei Zhao
IPC分类号： A61F2/02 , A61L27/38 , A61L27/56 , C12N5/00 , C12M1/12 , C12M1/22
CPC分类号： C12N5/0068 , A61L27/08 , A61L27/383 , A61L27/3878 , A61L27/56 , A61L2400/12 , A61L2430/32 , B05D1/02 , B05D3/007 , C12M23/10 , C12M25/10 , C12N2533/10
摘要： A neural graft includes a biological substrate, a carbon nanotube structure and a neural network. The carbon nanotube structure is located on the biological substrate. The carbon nanotube structure includes a number of carbon nanotube wires crossed with each other to define a number of pores. The neural network includes a number of neural cell bodies and a number of neurites branched from the neural cell bodies. An effective diameter of each pore is larger than or equal to a diameter of the neural cell body, the neurites substantially extend along the carbon nanotube wires such that the neurites are patterned.
摘要翻译：神经移植物包括生物底物，碳纳米管结构和神经网络。碳纳米管结构位于生物基底上。碳纳米管结构包括多个彼此交叉以形成多个孔的碳纳米管线。神经网络包括许多神经细胞体和从神经细胞体分支的许多神经突。每个孔的有效直径大于或等于神经细胞体的直径，神经突基本上沿着碳纳米管线延伸，使得神经突被图案化。

28. 发明授权

US09073753B2 Method for making hydrophilic carbon nanotube film 有权
标题翻译：制造亲水性碳纳米管膜的方法
公开(公告)号：US09073753B2
公开(公告)日：2015-07-07
申请号：US12978549
申请日：2010-12-25
申请人： Zhi-Min Tao , Li Fan , Wen-Mei Zhao
发明人： Zhi-Min Tao , Li Fan , Wen-Mei Zhao
IPC分类号： C09C1/56 , D01F9/12 , B82Y40/00 , C01B31/02 , B82Y30/00
CPC分类号： B82Y40/00 , B82Y30/00 , C01B32/174
摘要： A method for making a hydrophilic carbon nanotube film is provided. A reactor, an oxidative acid solution disposed in the reactor, and at least one primary carbon nanotube film are provided. The primary carbon nanotube film is set in the reactor disposed apart from the oxidative acid solution. The oxidative acid solution is then volatilized to form oxidative acid gas and the reactor is filled with the oxidative acid gas.
摘要翻译：提供一种制造亲水性碳纳米管膜的方法。提供反应器，设置在反应器中的氧化酸溶液和至少一个初级碳纳米管膜。将初级碳纳米管薄膜放置在离开氧化酸溶液的反应器中。然后将氧化酸溶液挥发以形成氧化性酸性气体，反应器充满氧化性气体。

29. 发明授权

US08626315B2 Electronic pacemaker and pacemaker electrode 有权
标题翻译：电子起搏器和起搏器电极
公开(公告)号：US08626315B2
公开(公告)日：2014-01-07
申请号：US13096200
申请日：2011-04-28
申请人： Kai Liu , Li Fan , Wen-Mei Zhao , Ying-Hui Sun
发明人： Kai Liu , Li Fan , Wen-Mei Zhao , Ying-Hui Sun
IPC分类号： A61N1/00
CPC分类号： A61N1/0529 , A61N1/057
摘要： A pacemaker includes a pulse generator, a conduction line, and a pacemaker electrode. The pacemaker electrode includes a body and an insulation layer. The body includes at least one carbon nanotube yarn. The carbon nanotube yarn includes a number of carbon nanotubes. The carbon nanotubes are interconnected along one axis of the body by van der Waals force. The insulation layer covers an outer surface of the body.
摘要翻译：起搏器包括脉冲发生器，导线和起搏器电极。起搏器电极包括主体和绝缘层。身体包括至少一个碳纳米管纱线。碳纳米管纱线包括多个碳纳米管。碳纳米管通过范德华力与身体的一个轴线相互连接。绝缘层覆盖主体的外表面。

30. 发明授权

US09309494B2 Method for making nerve graft 有权
标题翻译：神经移植方法
公开(公告)号：US09309494B2
公开(公告)日：2016-04-12
申请号：US12981581
申请日：2010-12-30
申请人： Li Fan , Chen Feng , Wen-Mei Zhao
发明人： Li Fan , Chen Feng , Wen-Mei Zhao
IPC分类号： C12N5/079 , C12N5/0793 , A61L27/34 , A61L27/38
CPC分类号： C12N5/0619 , A61L27/34 , A61L27/383 , A61L27/3878 , A61L2400/12 , A61L2430/32 , C12N2533/20 , C12N2533/32 , C12N2533/50 , C12N2535/00 , C08L89/00
摘要： A method for making a nerve graft includes the following steps. A culture layer including a carbon nanotube film structure and a protein layer is provided. The protein layer is located on a surface of the carbon nanotube film structure. A number of nerve cells are seeded on a surface of the protein layer away from the carbon nanotube film structure. The nerve cells are cultured until a number of neurites branch from the nerve cells and are connected between the nerve cells.
摘要翻译：制造神经移植物的方法包括以下步骤。提供了包括碳纳米管膜结构和蛋白质层的培养层。蛋白质层位于碳纳米管膜结构的表面上。将多个神经细胞接种在远离碳纳米管膜结构的蛋白质层的表面上。将神经细胞培养直到许多神经突从神经细胞分支并连接在神经细胞之间。

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