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21. 发明专利

AU2007349806A1 Ocular radiosurgery 未知
公开(公告)号：AU2007349806A1
公开(公告)日：2008-10-02
申请号：AU2007349806
申请日：2007-10-16
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL
IPC分类号： A61N5/10 , A61B5/00
摘要： A radiosurgery system describes a therapeutic radiation delivery to a target structure in a patient. The radiosurgery system treats inflammatory ocular disorders; places ocular structures in a global coordinate system based on ocular imaging; automates ocular structures inside the global coordinate system to direction of a positioning system that is directed based on ocular structures within the coordinate system; tracks and relates the position of ocular structures to the status of the radiosurgery system; determines beam energy and direction and duration of time for treatment for a specific disease to be treated and/or structures to be avoided; tracks structure of an eye; holds and fixes the eye is in place; places a fiducial is on the eye to aid in positioning; positions the eye off the refelction; and combines with other treatments and can be delivered concomitant with, prior to, or following other treatments.

22. 发明专利

HK1219913A1 眼放射外科未知
公开(公告)号：HK1219913A1
公开(公告)日：2017-04-21
申请号：HK16108019
申请日：2016-07-08
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , CHELL ERIK , HANSEN STEVEN , ARNOLDUSSEN MARK , HERRON MATT , PAN KUANG-HUNG
IPC分类号： A61N20060101

23. 发明专利

ES2600146T3 Conjunto para posicionar, estabilizar y tratar un ojo 未知
公开(公告)号：ES2600146T3
公开(公告)日：2017-02-07
申请号：ES13160734
申请日：2008-04-17
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , ARNOLDUSSEN MARK , HERRON MATT
IPC分类号： A61F9/009 , A61B3/00
摘要： Un conjunto (110) de contacto con ojo para estabilizar el ojo de un paciente en una posición seleccionada en un sistema de coordenadas externo, que comprende: un miembro (120) de contacto con ojo que comprende una superficie de contacto interior para contactar en una superficie delantera del ojo de un paciente (130), una superficie exterior y una lumbrera de vacío (210) formada dentro del miembro (120) de contacto con ojo por la que se puede aplicar una presión negativa entre el ojo (130) de un paciente y la superficie de contacto, para estabilizar la posición del ojo con respecto al miembro de contacto (120), un brazo de posicionamiento (180) para posicionar el miembro (120) de contacto con ojo en una posición seleccionada, con el ojo (130) de un paciente estabilizado en el mismo, miembros de acoplamiento liberables (410, 415; 412, 417) llevados en el miembro de contacto (120) y brazo de posicionamiento (180), los miembros de acoplamiento liberables (410, 415; 412, 417) se acoplan de manera liberable entre sí con una fuerza de liberación suficiente para permitir al miembro de contacto (120) y al ojo (130) de un paciente estabilizado en el mismo ser movidos por el brazo (180), y los miembros de acoplamiento liberables (410, 415; 412, 417) se configuran para liberarse uno de otro cuando una fuerza por encima de umbral superior a la fuerza de liberación es aplicada por el ojo o se aplica a este; en donde uno o más sensores de presión (450, 452, 454) se colocan en un miembro de acoplamiento (410, 415; 412, 417) y una unidad de control (115), configurada para controlar el brazo de posicionamiento (180), en donde, cuando se alcanza una fuerza umbral sobre y hacia el ojo (130) del paciente por el miembro (120) de contacto con ojo, la unidad de control (115) restringe el movimiento adicional del brazo de posicionamiento (180) y el miembro (120) de contacto con ojo hacia el ojo (130) mientras el ojo (130) del paciente permanece estabilizado en el miembro de contacto (120), en donde la fuerza es monitorizada por los sensores de presión.

24. 发明专利

AU2016201833A1 OCULAR RADIOSURGERY 未知
公开(公告)号：AU2016201833A1
公开(公告)日：2016-04-14
申请号：AU2016201833
申请日：2016-03-23
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , ARNOLDUSSEN MARK , HERRON MATT , CHELL ERIK , KUANG-HUNG PAN , HANSEN STEVEN D
IPC分类号： A61N5/10 , A61B5/00
摘要： A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the 5 ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system, hi some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In 10 some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system, hi some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial 15 is placed on the eye to aid in positioning, hi some embodiments, a reflection off the eye is used to aid in positioning, hi some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments. Page 1 of 35 --- - - - 210--- ' 3 u140

25. 发明专利

AU2012261645A1 OCULAR RADIOSURGERY 未知
公开(公告)号：AU2012261645A1
公开(公告)日：2013-01-10
申请号：AU2012261645
申请日：2012-12-06
申请人： ORAYA THERAPEUTICS INC
发明人： ERIK CHELL , PAN KUANG-HUNG , ARNOLDUSSEN MARK , HERRON MATT , GERTNER MICHAEL , HANSEN STEVEN D
IPC分类号： A61N5/10 , A61B5/00
摘要： A radiosurgery system is described that is configured to deliver a therapeutic dose of radiation to a target structure in a patient. In some embodiments, inflammatory ocular disorders are treated, specifically macular degeneration. In some embodiments, the 5 ocular structures are placed in a global coordinate system based on ocular imaging. In some embodiments, the ocular structures inside the global coordinate system lead to direction of an automated positioning system that is directed based on the ocular structures within the coordinate system, hi some embodiments, the position of the ocular structure is tracked and related to the status of the radiosurgery system. In 10 some embodiments, a treatment plan is utilized in which beam energy and direction and duration of time for treatment is determined for a specific disease to be treated and/or structures to be avoided. In some embodiments, the structure is an eye and the eye is tracked by the system, hi some embodiments, the eye is held in place and in some embodiments, the eye is fixed by the patient. In some embodiments, a fiducial 15 is placed on the eye to aid in positioning, hi some embodiments, a reflection off the eye is used to aid in positioning, hi some embodiments, radiodynamic therapy is described in which radiosurgery is used in combination with other treatments and can be delivered concomitant with, prior to, or following other treatments. Page 1 of 35 - -- -400

26. 发明专利

CA2925590A1 OCULAR RADIOSURGERY 未知
公开(公告)号：CA2925590A1
公开(公告)日：2008-10-02
申请号：CA2925590
申请日：2007-10-16
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , CHELL ERIK , HANSEN STEVEN D , ARNOLDUSSEN MARK , HERRON MATT , PAN KUANG-HUNG
IPC分类号： A61N5/00 , A61B6/00 , A61F9/007 , A61N5/10
摘要： A radiosurgery system describes a therapeutic radiation delivery to a target structure in a patient. The radiosurgery system treats inflammatory ocular disorders; places ocular structures in a global coordinate system based on ocular imaging; automates ocular structures inside the global coordinate system to direction of a positioning system that is directed based on ocular structures within the coordinate system; tracks and relates the position of ocular structures to the status of the radiosurgery system; determines beam energy and direction and duration of time for treatment for a specific disease to be treated and/or structures to be avoided; tracks structure of an eye; holds and fixes the eye is in place; places a fiducial is on the eye to aid in positioning; positions the eye off the reflection; and combines with other treatments and can be delivered concomitant with, prior to, or following other treatments.

27. 发明公开

EP2152142A4 DEVICE AND ASSEMBLY FOR POSITIONING, STABILIZING AND TREATING AN EYE 有权
标题翻译：设备和装置的定位，稳定与治疗眼睛
公开(公告)号：EP2152142A4
公开(公告)日：2011-06-29
申请号：EP08743035
申请日：2008-04-17
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , ARNOLDUSSEN MARK , HERRON MATT
IPC分类号： A61F9/008 , A61B3/00
CPC分类号： A61F9/008 , A61B3/113 , A61B3/12 , A61B3/152 , A61B17/0231 , A61F9/00804 , A61F9/00808 , A61F9/009 , A61F2009/00846 , A61F2009/00865 , A61N5/1017 , A61N5/1049 , A61N2005/1059 , A61N2005/1091

28. 发明公开

EP2231276A4 METHODS AND DEVICES FOR ORTHOVOLTAGE OCULAR RADIOTHERAPY AND TREATMENT PLANNING 审中-公开
标题翻译：方法和设备目镜ORTHO电压放射治疗和治疗计划
公开(公告)号：EP2231276A4
公开(公告)日：2011-04-06
申请号：EP08859241
申请日：2008-10-31
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , ARNOLDUSSEN MARK , CHELL ERIK , HANSEN STEVEN D , LIANG JUNZHONG
IPC分类号： A61N5/10
CPC分类号： A61N5/1037 , A61N5/1017 , A61N5/103 , A61N5/1064 , A61N2005/1091
摘要： A method, code and system for planning the treatment a lesion on or adjacent to the retina of an eye of a patient are disclosed. There is first established at least two beam paths along which x-radiation is to be directed at the retinal lesion. Based on the known spectral and intensity characteristics of the beam, a total treatment time for irradiation along each beam paths is determined. From the coordinates of the optic nerve in the aligned eye position, there is determined the extent and duration of eye movement away from the aligned patient-eye position in a direction that moves the patient's optic nerve toward the irradiation beam that will be allowed during treatment, while still maintaining the radiation dose at the patient optic nerve below a predetermined dose level.

29. 发明公开

EP2077901A4 OCULAR RADIOSURGERY 有权
标题翻译：目镜定向放射外科
公开(公告)号：EP2077901A4
公开(公告)日：2011-06-29
申请号：EP07873549
申请日：2007-10-16
申请人： ORAYA THERAPEUTICS INC
发明人： GERTNER MICHAEL , CHELL ERIK , HANSEN STEVEN D , ARNOLDUSSEN MARK , HERRON MATT , PAN KUANG-HUNG
IPC分类号： A61N5/10
CPC分类号： A61N5/1049 , A61B6/506 , A61B2017/306 , A61F9/009 , A61N5/1017 , A61N5/103 , A61N2005/105 , A61N2005/1056 , A61N2005/1091

30. 发明公开

EP2964086A4 TRANSDUCERS, SYSTEMS, AND MANUFACTURING TECHNIQUES FOR FOCUSED ULTRASOUND THERAPIES 审中-公开
标题翻译： WANDLER，SYSTEME UND VERFAHRENFÜRFOKUSSIERTE ULTRASCHALLTHERAPIEN
公开(公告)号：EP2964086A4
公开(公告)日：2017-02-15
申请号：EP14780306
申请日：2014-03-07
申请人： KONA MEDICAL INC , ZHANG JIMIN , GERTNER MICHAEL
发明人： ZHANG JIMIN , GERTNER MICHAEL
IPC分类号： A61B5/05 , A61N7/02
CPC分类号： A61B8/4494 , A61B6/12 , A61B6/487 , A61B8/0841 , A61B8/085 , A61B8/4209 , A61B8/4245 , A61B8/4254 , A61B8/4281 , A61B8/4416 , A61B2017/00725 , A61B2018/00023 , A61B2034/2063 , A61B2090/378 , A61B2090/3937 , A61B2090/395 , A61N7/02 , A61N2007/0065 , A61N2007/0082 , A61N2007/0091 , A61N2007/0095

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