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21. 发明公开

EP3273839A1 MULTIPLE DEPTH OPTICAL COHERENCE TOMOGRAPHY SYSTEM AND METHOD AND LASER EYE SURGERY SYSTEM INCORPORATING THE SAME 有权转让
标题翻译：多层深度光学相干层析摄影系统和包含该层的方法和激光眼外科手术系统
公开(公告)号：EP3273839A1
公开(公告)日：2018-01-31
申请号：EP15821214.2
申请日：2015-12-16
申请人： Optimedica Corporation
发明人： SCHUELE, Georg
IPC分类号： A61B3/10
CPC分类号： A61B3/102 , A61B3/1005 , A61B3/117 , A61B3/1225 , A61F9/008 , A61F2009/00851 , A61F2009/00863 , A61F2009/0087
摘要： An OCT system for imaging multiple depth positions includes a light source, a sample arm and two or more reference arms. The sample arm propagates light to the object and directs object return light having a first return light beam from a first position and a second return light beam from a second position, the second return light having a dispersion level higher than the first return light beam by a dispersion difference amount. The first and second reference arms produce light beams having substantially the same dispersion as the first and second return light beams, respectively. The optical pathway combines all of the object return light and the reference light beams. An OCT detector measures the resulting interferogram. Imaging information is obtained for both the first position and the second position based on the dispersion difference amount.

22. 发明公开

EP3206644A1 CORNEAL TOPOGRAPHY MEASUREMENTS AND FIDUCIAL MARK INCISIONS IN LASER SURGICAL PROCEDURES 审中-公开
标题翻译：激光手术中的角膜地形图测量和假体标记
公开(公告)号：EP3206644A1
公开(公告)日：2017-08-23
申请号：EP15788279.6
申请日：2015-10-16
申请人： Optimedica Corporation
发明人： SRINIVASAN, Rajeshwari , GOLDA, Jeffrey A. , GONZALEZ, Javier G. , SCOTT, David D. , DEWEY, David A. , BAREKET, Noah , SCHUELE, Georg
IPC分类号： A61F9/008
CPC分类号： A61F9/00825 , A61F2009/00865 , A61F2009/0087 , A61F2009/00872 , A61F2009/00882
摘要： A method of cataract surgery in an eye of a patient includes identifying a feature selected from the group consisting of an axis, a meridian, and a structure of an eye by corneal topography and forming fiducial mark incisions with a laser beam along the axis, meridian or structure in the cornea outside the optical zone of the eye. A laser cataract surgery system a laser source, a topography measurement system, an integrated optical subsystem, and a processor in operable communication with the laser source, corneal topography subsystem and the integrated optical system. The processor includes a tangible non- volatile computer readable medium comprising instructions to determine one of an axis, meridian and structure of an eye of the patient based on the measurements received from topography measurement system, and direct the treatment beam so as to incise radial fiducial mark incisions.
摘要翻译：一种在患者眼睛中进行白内障手术的方法包括通过角膜地形图识别从由轴，子午线和眼睛结构组成的组中选择的特征，并且利用沿轴的激光束形成基准标记切口，子午线或眼睛光学区域外角膜中的结构。激光白内障手术系统包括激光源，地形测量系统，集成光学子系统以及与激光源，角膜地形子系统和集成光学系统可操作通信的处理器。该处理器包括有形的非易失性计算机可读介质，该介质包括用于基于从地形测量系统接收到的测量结果来确定患者的眼睛的轴线，子午线和结构中的一个的指令，并且指导治疗梁以切割径向基准点标记切口。

23. 发明公开

EP3122298A1 AUTOMATED CALIBRATION OF LASER SYSTEM AND TOMOGRAPHY SYSTEM WITH FLUORESCENT IMAGING OF SCAN PATTERN 有权转让
标题翻译：自动化KALIBRIUNG EINES LASERSYSTEMS UND TOMOGRAFIESYSTEM MIT FLUORESZIERENDER ABBILDUNG VON ABTASTMUSTERN
公开(公告)号：EP3122298A1
公开(公告)日：2017-02-01
申请号：EP15717703.1
申请日：2015-03-24
申请人： Optimedica Corporation
发明人： SIMONEAU, Michael , HART, John Scot , SCHUELE, Georg
IPC分类号： A61F9/008 , B23K26/08
CPC分类号： A61F9/00814 , A61B90/361 , A61F9/008 , A61F9/00823 , A61F9/0084 , A61F2009/00846 , A61F2009/00851 , A61F2009/00855 , A61F2009/00857 , A61F2009/00897 , B23K26/082
摘要： A laser system calibration method and system are provided. In some methods, a calibration plate may be used to calibrate a video camera of the laser system. The video camera pixel locations may be mapped to the physical space. A xy-scan device of the laser system may be calibrated by defining control parameters for actuating components of the xy-scan device to scan a beam to a series of locations. Optionally, the beam may be scanned to a series of locations on a fluorescent plate. The video camera may be used to capture reflected light from the fluorescent plate. The xy-scan device may then be calibrated by mapping the xy-scan device control parameters to physical locations. A desired z-depth focus may be determined by defining control parameters for focusing a beam to different depths. The video camera or a confocal detector may be used to detect the scanned depths.
摘要翻译：提供了一种激光系统校准方法和系统。在某些方法中，校准板可用于校准激光系统的摄像机。摄像机像素位置可以映射到物理空间。激光系统的xy扫描装置可以通过定义用于启动xy扫描装置的部件的控制参数来校准，以将光束扫描到一系列位置。可选地，光束可以被扫描到荧光板上的一系列位置。摄像机可用于捕获来自荧光板的反射光。然后可以通过将xy扫描装置控制参数映射到物理位置来校准xy扫描装置。可以通过定义用于将光束聚焦到不同深度的控制参数来确定期望的z深度焦点。摄像机或共焦检测器可用于检测扫描深度。

24. 发明公开

EP2986259A2 CORNEAL TOPOGRAPHY MEASUREMENT AND ALIGNMENT OF CORNEAL SURGICAL PROCEDURES 有权转让
标题翻译：角膜地形图测量和外科手术对于方向角膜
公开(公告)号：EP2986259A2
公开(公告)日：2016-02-24
申请号：EP14725338.9
申请日：2014-04-18
申请人： Optimedica Corporation
发明人： SCOTT, David, D. , GONZALEZ, Javier , DEWEY, David , BAREKET, Noah , SCHUELE, Georg
IPC分类号： A61F9/009
CPC分类号： A61F9/00825 , A61B3/10 , A61B3/107 , A61B5/0073 , A61F9/00827 , A61F9/00829 , A61F2009/00846 , A61F2009/00853 , A61F2009/0087 , A61F2009/00872 , A61F2009/0088 , A61F2009/00882 , A61F2009/00887 , A61F2009/00889
摘要： Methods and apparatus are configures to measure an eye without contacting the eye with a patient interface, and these measurements are used to determine alignment and placement of the incisions when the patient interface contacts the eye. The pre-contact locations of one or more structures of the eye can be used to determine corresponding post-contact locations of the one or more optical structures of the eye when the patient interface has contacted the eye, such that the laser incisions are placed at locations that promote normal vision of the eye. The incisions are positioned in relation to the pre-contact optical structures of the eye, such as an astigmatic treatment axis, nodal points of the eye, and visual axis of the eye.

25. 发明公开

EP3434235A1 LASER EYE SURGERY SYSTEM 有权转让
公开(公告)号：EP3434235A1
公开(公告)日：2019-01-30
申请号：EP18180964.1
申请日：2014-02-26
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , GOODING, Phillip
IPC分类号： A61F9/008 , A61B3/10
摘要： An imaging system includes an eye interface device, a scanning assembly, a beam source, a free-floating mechanism, and a detection assembly. The eye interface device interfaces with an eye. The scanning assembly supports the eye interface device and scans a focal point of an electromagnetic radiation beam within the eye. The beam source generates the electromagnetic radiation beam. The free-floating mechanism supports the scanning assembly and accommodates movement of the eye and provides a variable optical path for the electronic radiation beam and a portion of the electronic radiation beam reflected from the focal point location. The variable optical path is disposed between the beam source and the scanner and has an optical path length that varies to accommodate movement of the eye. The detection assembly generates a signal indicative of intensity of a portion of the electromagnetic radiation beam reflected from the focal point location.

26. 发明公开

EP3316833A1 SUB-NANOSECOND LASER SURGERY SYSTEM UTILIZING MULTIPLE PULSED LASER BEAMS 有权转让
标题翻译：利用多脉冲激光束的亚纳秒激光手术系统
公开(公告)号：EP3316833A1
公开(公告)日：2018-05-09
申请号：EP16733264.2
申请日：2016-06-15
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , ANDERSEN, Daniel J. , VANKOV, Alexander , GOODING, Phillip H.
IPC分类号： A61F9/007 , A61F9/008
CPC分类号： A61F9/00825 , A61F9/00736 , A61F9/00754 , A61F9/00814 , A61F9/009 , A61F2009/00844 , A61F2009/00851 , A61F2009/0087 , A61F2009/00872 , A61F2009/00887 , A61F2009/00889 , A61F2009/00897
摘要： Systems and methods for fragmenting a lens by a laser cataract surgery system includes a sub-nanosecond laser source generating a treatment beam that includes a plurality of laser beam pulses. An optical delivery system is coupled to the sub-nanosecond laser source to receive and direct the treatment beam. A processor is coupled to the sub-nanosecond laser source and the optical delivery system. The processor includes a tangible non-volatile computer readable medium comprising instructions to determine a lens cut pattern for lens fragmentation and determine a plurality of energies of the treatment beam as a linear function of a depth of the lens cut pattern. The treatment beam is output according to the lens cut pattern and the determined energies.

27. 发明授权

EP2967999B1 LASER CAPSULOVITREOTOMY 有权
标题翻译： LASER-KAPSULOVITREKTOMIE
公开(公告)号：EP2967999B1
公开(公告)日：2017-04-19
申请号：EP14709516.0
申请日：2014-02-26
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , STEVENS, Julian , ANDERSEN, Dan, E.
IPC分类号： A61F9/008
CPC分类号： A61F9/00834 , A61F9/008 , A61F9/00836 , A61F2009/0087 , A61F2009/00889
摘要： Methods and systems for performing laser-assisted surgery on an eye form a layer of bubbles in the Berger's space of the eye to increase separation between the posterior portion of the lens capsule of the eye and the anterior hyaloid surface of the eye. A laser is used to form the layer of bubbles in the Berger's space. The increased separation between the posterior portion of the lens capsule and the anterior hyaloid surface can be used to facilitate subsequent incision of the posterior portion of the lens capsule with decreased risk of compromising the anterior hyaloid surface. For example, the layer of bubbles can be formed prior to performing a capsulotomy on the posterior portion of the lens capsule.
摘要翻译：用于在眼睛上进行激光辅助手术的方法和系统在Berger的眼睛空间中形成一层气泡，以增加眼睛的晶状体囊的后部与眼睛的前眼球表面之间的分离。在伯格的空间中，激光用于形成气泡层。透镜胶囊的后部与前面的玻璃体表面之间的增加的间隔可以用于促进透镜胶囊的后部部分的后续切口，同时降低了前面的玻璃体表面的风险。例如，可以在透镜胶囊的后部进行囊切术之前形成气泡层。

28. 发明公开

EP2967999A1 LASER CAPSULOVITREOTOMY 有权
标题翻译：激光胶囊手术
公开(公告)号：EP2967999A1
公开(公告)日：2016-01-20
申请号：EP14709516.0
申请日：2014-02-26
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , STEVENS, Julian , ANDERSEN, Dan, E.
IPC分类号： A61F9/008
CPC分类号： A61F9/00834 , A61F9/008 , A61F9/00836 , A61F2009/0087 , A61F2009/00889
摘要： Methods and systems for performing laser-assisted surgery on an eye form a layer of bubbles in the Berger's space of the eye to increase separation between the posterior portion of the lens capsule of the eye and the anterior hyaloid surface of the eye. A laser is used to form the layer of bubbles in the Berger's space. The increased separation between the posterior portion of the lens capsule and the anterior hyaloid surface can be used to facilitate subsequent incision of the posterior portion of the lens capsule with decreased risk of compromising the anterior hyaloid surface. For example, the layer of bubbles can be formed prior to performing a capsulotomy on the posterior portion of the lens capsule.
摘要翻译：用于在眼睛上执行激光辅助手术的方法和系统在眼睛的伯格空间中形成一层气泡，以增加眼睛晶状体囊的后部与眼睛的前玻璃体表面之间的分离。激光用于在伯杰空间形成气泡层。晶状体囊后部与前玻璃体表面之间的增加的分离可以用于促进随后切开晶状体囊的后部，同时降低损害前部玻璃体表面的风险。例如，可以在对晶状体囊的后部进行囊切开之前形成气泡层。

29. 发明公开

EP3628282A1 FREE FLOATING PATIENT INTERFACE FOR LASER SURGERY SYSTEM 有权转让
公开(公告)号：EP3628282A1
公开(公告)日：2020-04-01
申请号：EP19210087.3
申请日：2016-09-14
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , GOODING, Phillip H. , ANGELEY, David , WANG, Zhao
IPC分类号： A61F9/009 , A61F9/008
摘要： Systems and methods here may be used to support a femtosecond laser eye surgery system including utilizing a floating head and/or patient support to maintain alignment of the system with a patient using feedback loops of force sensors in a patient interface. In some examples, the floating head and/or patient support may counteract movements detected in the force sensors. In some example embodiments, a ranging subsystem may detect and compensate for different arrangements of the floating head assembly using a ranging sample beam.

30. 发明公开

EP3195838A1 LASER CAPSULOVITREOTOMY 有权
公开(公告)号：EP3195838A1
公开(公告)日：2017-07-26
申请号：EP17152041.4
申请日：2014-02-26
申请人： Optimedica Corporation
发明人： SCHUELE, Georg , STEVENS, Julian , ANDERSEN, Dan, E.
IPC分类号： A61F9/008
CPC分类号： A61F9/00834 , A61F9/008 , A61F9/00836 , A61F2009/0087 , A61F2009/00889
摘要： Methods and systems for performing laser-assisted surgery on an eye form a layer of bubbles in the Berger's space of the eye to increase separation between the posterior portion of the lens capsule of the eye and the anterior hyaloid surface of the eye. A laser is used to form the layer of bubbles in the Berger's space. The increased separation between the posterior portion of the lens capsule and the anterior hyaloid surface can be used to facilitate subsequent incision of the posterior portion of the lens capsule with decreased risk of compromising the anterior hyaloid surface. For example, the layer of bubbles can be formed prior to performing a capsulotomy on the posterior portion of the lens capsule.

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