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21. 发明授权

US07691577B2 Protein having an EGF-like repeat sequence 失效
标题翻译：具有EGF样重复序列的蛋白质
公开(公告)号：US07691577B2
公开(公告)日：2010-04-06
申请号：US11475860
申请日：2006-06-28
申请人： Noriko Nakamura , Tetsuo Sudo , Takatoshi Yamada
发明人： Noriko Nakamura , Tetsuo Sudo , Takatoshi Yamada
IPC分类号： C12N15/11 , C12N15/63 , C12N5/10 , C12Q1/68
CPC分类号： C07K14/475 , C07K14/485 , C07K2319/30 , C07K2319/43
摘要： The present invention provides SELF protein having controlling effects on growth and differentiation of undifferentiated cells, wherein the protein contains a novel EGF-like repeat sequence, SELF gene encoding the same, a recombinant vector and a transformed cell containing the SELF gene, a method for treatment or prophylaxis with SELF protein or a recombinant expression vector containing SELF gene, SELF promoter, a recombinant vector and a transformed cell containing SELF promoter, and a screening method using the transformed cell containing SELF promoter.
摘要翻译：本发明提供具有对未分化细胞的生长和分化具有控制作用的SELF蛋白质，其中所述蛋白质含有新的EGF样重复序列，编码其的SELF基因，重组载体和含有SELF基因的转化细胞， SELF蛋白或包含SELF基因，SELF启动子，重组载体和含有SELF启动子的转化细胞的重组表达载体的治疗或预防以及使用含有SELF启动子的转化细胞的筛选方法。

22. 发明申请

US20120220758A1 ANTIBODY HAVING ACTIVITY OF INHIBITING HEPATITIS C VIRUS (HCV) INFECTION AND USE THEREOF 失效
标题翻译：具有抑制性乙型肝炎病毒（HCV）感染的活性的抗体及其用途
公开(公告)号：US20120220758A1
公开(公告)日：2012-08-30
申请号：US13504765
申请日：2010-10-29
申请人： Takaji Wakita , Kazumi Nishimura , Noriko Nakamura , Daisuke Akazawa
发明人： Takaji Wakita , Kazumi Nishimura , Noriko Nakamura , Daisuke Akazawa
IPC分类号： C07K16/08 , C12N5/16
CPC分类号： C07K16/109 , A61K2039/505 , C07K2317/30 , C07K2317/76
摘要： An object of the present invention is to provide an antibody inhibiting infection with hepatitis C virus (HCV). The present invention provides an anti-hepatitis C virus antibody that recognizes a whole or a part of the conformation of a hepatitis C virus particle as an epitope and binds thereto, so as to be able to inhibit the binding of hepatitis C virus to the surface of a host cell and to inhibit HCV infection, a humanized antibody thereof, and an inhibitory agent for infection with hepatitis C virus.
摘要翻译：本发明的目的是提供抗丙型肝炎病毒（HCV）的抗体抑制感染。本发明提供一种抗丙型肝炎病毒抗体，其识别丙型肝炎病毒颗粒的构象的全部或一部分作为表位并与其结合，从而能够抑制丙型肝炎病毒与表面的结合的宿主细胞并抑制HCV感染，其人源化抗体和用于感染丙型肝炎病毒的抑制剂。

23. 发明授权

US5705234A Method for manufacturing magnetic hard disk 失效
标题翻译：制造磁性硬盘的方法
公开(公告)号：US5705234A
公开(公告)日：1998-01-06
申请号：US779630
申请日：1997-01-07
申请人： Motokazu Yamamoto , Noriko Nakamura
发明人： Motokazu Yamamoto , Noriko Nakamura
IPC分类号： C23C14/14 , G11B5/84 , H05H1/48 , H05H1/32
CPC分类号： G11B5/8404 , H05H1/48
摘要： An object of the present invention is to provide a method for manufacturing a magnetic hard disk wherein a magnetic material layer adhered on a surface of a substrate of the magnetic hard disk has a flat surface. A method for manufacturing a magnetic hard disk comprising steps of: structurally transforming a surface of an amorphous Ni--P alloy film layer formed a substrate (10) of the magnetic hard disk; and adhering a magnetic material layer on the surface of a substrate (10), wherein the step of structurally transforming the a-Ni--P alloy film layer is a step of heating only a desired portion of the surface of the substrate (10) by an electric discharge to generate Ni and crystallized compounds of Ni and P only at the desired portion (T) of the surface thereof. The electric discharge in the step of structurally transforming the a-Ni--P alloy film layer is carried out by applying a discharge potential between at least one electric discharger (11) and a metallic table (12) as an electrode which carries the substrate (10) thereon, the electric discharger (11) being positioned in opposite to the surface of the substrate (10).
摘要翻译：本发明的目的是提供一种磁性硬盘的制造方法，其中粘附在磁性硬盘的基板的表面上的磁性材料层具有平坦的表面。一种制造磁性硬盘的方法，包括以下步骤：对形成所述磁性硬盘的基板（10）的非晶Ni-P合金膜层的表面进行结构转化; 在所述基板（10）的表面上附着磁性材料层，其中，所述a-Ni-P合金膜层的结构变形步骤是仅将基板（10）的表面的期望部分加热的工序为：在其表面的期望部分（T）仅产生Ni和Ni和P的结晶化合物的放电。在a-Ni-P合金膜层的结构转化步骤中的放电是通过在至少一个放电器（11）和金属台（12）之间施加放电电位，作为承载衬底的电极 10），放电器（11）位于与基板（10）的表面相对的位置。

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