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21. 发明授权

US07273939B1 Methods of making tris(N-aryl benzimidazoles)benzenes and their use in electronic devices 失效
标题翻译：制备三（N-芳基苯并咪唑）苯的方法及其在电子器件中的应用
公开(公告)号：US07273939B1
公开(公告)日：2007-09-25
申请号：US11305480
申请日：2005-12-15
申请人： Mark A. Guidry , Steven W. Shuey , William J. Delaney
发明人： Mark A. Guidry , Steven W. Shuey , William J. Delaney
IPC分类号： C07D403/10
CPC分类号： C07D401/14 , C07D235/14 , C07D405/14
摘要： Provided are methods for preparing a compound of Formula I: where the method comprises the steps of: contacting a compound of Formula II: with 1,3,5-benzene-tricarbonyl chloride in the presence of a polar aprotic solvent to form an amide adduct; and subsequently condensing the amide with a proximate anilino group present in the adduct in the presence of a condensing agent to form a compound of Formula I wherein R1, R2, Ar, m, p, and t are as defined in the specification.
摘要翻译：提供制备式I化合物的方法：其中该方法包括以下步骤：在极性非质子溶剂存在下使式II化合物与1,3,5-苯三羰基氯接触以形成酰胺加合物 ; 并随后在存在缩合剂的情况下将酰胺与存在于加合物中的邻近苯胺基缩合，以形成式I化合物，其中R 1，R 2，Ar ，m，p和t如说明书中所定义。

22. 发明授权

US5908926A 5'to 3' nucleic acid synthesis using 3'-photoremovable protecting group 失效
标题翻译： 5'-3'核酸合成，使用3'-可光去保护基团
公开(公告)号：US5908926A
公开(公告)日：1999-06-01
申请号：US406327
申请日：1995-03-16
申请人： Michael C. Pirrung , Steven W. Shuey , Jean-Claude Bradley
发明人： Michael C. Pirrung , Steven W. Shuey , Jean-Claude Bradley
IPC分类号： C12N15/09 , C07H19/10 , C07H19/20 , C07H21/00 , C07H21/02 , C07H21/04 , C07H1/02 , C07H1/00
CPC分类号： C07H19/10 , C07H19/20 , C07H21/00 , Y02P20/55
摘要： The present invention relates, in general, to a method of synthesizing a nucleic acid, and, in particular, to a method of effecting 5' to 3' nucleic acid synthesis. The method can be used to prepare arrays of oligomers bound to a support via their 5' end. The invention also relates to a method of effecting mutation analysis using such arrays. The invention further relates to compounds and compositions suitable for use in such methods.
摘要翻译：本发明一般涉及一种合成核酸的方法，特别涉及一种进行5'至3'核酸合成的方法。该方法可用于通过其5'末端制备与载体结合的低聚物阵列。本发明还涉及使用这种阵列进行突变分析的方法。本发明还涉及适用于这些方法的化合物和组合物。

23. 发明授权

US08580951B2 Aldehyde-functionalized polysaccharides 有权
标题翻译：醛官能化多糖
公开(公告)号：US08580951B2
公开(公告)日：2013-11-12
申请号：US12996477
申请日：2010-07-01
申请人： Helen S. M. Lu , Steven W. Shuey
发明人： Helen S. M. Lu , Steven W. Shuey
IPC分类号： C08B1/00 , C08B11/02 , C08B11/04 , C08B11/08 , C08B11/12 , C08B31/18 , C08B37/02 , C08B37/12 , C08B37/18 , C08L1/02 , C08L1/28 , C08L5/02 , C08L5/08 , C08L5/12
CPC分类号： C08B37/00 , C08B15/02 , C08B31/18 , C08B37/0021 , C08B37/0054 , C08L1/04 , C08L3/10 , C08L5/00 , C08L5/02
摘要： Novel aldehyde-functionalized polysaccharide compositions are described that are more stable in aqueous solution than oxidized polysaccharides or other types of polysaccharides containing pendant aldehyde groups. The aldehyde-functionalized polysaccharides may be reacted with various amine-containing polymers to form hydrogel tissue adhesives and sealants that may be useful for medical applications such as wound closure, supplementing or replacing sutures or staples in internal surgical procedures such as intestinal anastomosis and vascular anastomosis, tissue repair, preventing leakage of fluids such as blood, bile, gastrointestinal fluid and cerebrospinal fluid, ophthalmic procedures, drug delivery, and preventing post-surgical adhesions.
摘要翻译：描述了新型醛官能化多糖组合物，其在水溶液中比氧化多糖或其它类型的含醛侧基的多糖更稳定。醛官能化多糖可以与各种含胺聚合物反应以形成可用于医学应用的水凝胶组织粘合剂和密封剂，例如伤口闭合，补充或替换缝合或缝合在内部外科手术如肠吻合和血管吻合中，组织修复，防止流体如血液，胆汁，胃肠道液体和脑脊液的渗漏，眼科手术，药物递送和预防手术后粘连。

24. 发明授权

US08470208B2 Organometallic complexes 失效
标题翻译：有机金属配合物
公开(公告)号：US08470208B2
公开(公告)日：2013-06-25
申请号：US11654773
申请日：2007-01-18
申请人： Norman Herron , Steven W. Shuey , Jeffrey A. Merlo
发明人： Norman Herron , Steven W. Shuey , Jeffrey A. Merlo
IPC分类号： H01B1/12 , H01L29/08 , H01J1/62 , C09K11/06 , C07D215/30
CPC分类号： H01L51/5016 , C09K11/06 , C09K2211/186 , H01L51/0081 , H01L51/0084 , H01L51/5048 , H05B33/20
摘要： The present disclosure relates to organometallic complexes and electronic devices containing the complexes. The complexes have the formula MYnZ, where n is 1, 2, or 3; M is a metal in a +2, +3, or +4 oxidation state, Y is selected from an 8-hydroxyquinolate and a substituted 8-hydroxyquinolate, and Z is a phenolate. At least one Y is a substituted 8-hydroxyquinolate having the formula where: R1 and R2 are the same or different at each occurrence and each represents one or more of a substituent selected from the group consisting of H, alkyl, fluoroalkyl, aryl, fluoroaryl, alkylaryl, alkoxy, aryloxy, fluoroalkoxy, fluoroaryloxy, heteroalkyl, fluoroheteroalkyl, heteroaryl, fluoroheteroaryl, heteroalkylaryl, heteroalkoxy, heteroaryloxy, fluoroheteroalkoxy, fluoroheteroaryloxy, a solvent-solubilizing group, and a Tg enhancing group, wherein at least one of R1 and R2 is a solvent-solubilizing or Tg enhancing group; and R3 is selected from the group consisting of H, an alkyl group, and a substituted alkyl group.
摘要翻译：本公开涉及含有该配合物的有机金属配合物和电子装置。络合物具有式MYnZ，其中n为1,2或3; M是+2，+3或+4氧化态的金属，Y选自8-羟基喹啉酸盐和取代的8-羟基喹喔啉，Z是酚盐。至少一个Y是具有下式的取代的8-羟基喹诺酸盐：其中：R1和R2在每次出现时相同或不同，并且各自表示一个或多个选自H，烷基，氟代烷基，芳基，氟代芳基烷基芳基，烷氧基，芳氧基，氟代烷氧基，氟芳氧基，杂烷基，氟杂芳基，杂芳基，氟杂芳基，杂烷基芳基，杂烷氧基，杂芳氧基，氟代杂环氧基，氟代杂芳基氧基，溶剂增溶基团和Tg增强基团，其中R1和R2中的至少一个是溶剂增溶或Tg增强基团; 并且R 3选自H，烷基和取代的烷基。

25. 发明授权

US07999121B2 Derivatized 3,4-alkylenedioxythiophene monomers, methods of making them, and use thereof 失效
标题翻译：衍生的3,4-亚烷基二氧噻吩单体，制备方法及其用途
公开(公告)号：US07999121B2
公开(公告)日：2011-08-16
申请号：US12903356
申请日：2010-10-13
申请人： Shawn Yeisley , Charles J. Dubois , Che-Hsiung Hsu , Steven W. Shuey , Yulong Shen , Hjalti Skulason
发明人： Shawn Yeisley , Charles J. Dubois , Che-Hsiung Hsu , Steven W. Shuey , Yulong Shen , Hjalti Skulason
IPC分类号： C07D495/02 , C07D333/50 , C08G75/32
CPC分类号： C07D495/04 , H05K3/424
摘要： The present invention relates to methods of making derivatized 3,4-alkylenedioxythiophene monomers and methods of using the 3,4-alkylenedioxythiophene monomers.
摘要翻译：本发明涉及制备衍生化的3,4-亚烷基二氧噻吩单体的方法和使用3,4-亚烷基二氧噻吩单体的方法。

26. 发明申请

US20080167433A1 METHOD FOR PREPARING GLYCIDYLOXYSTYRENE MONOMERS AND POLYMERS THEREOF 失效
标题翻译：制备甘氨酰基苯乙烯单体及其聚合物的方法
公开(公告)号：US20080167433A1
公开(公告)日：2008-07-10
申请号：US11961093
申请日：2007-12-20
申请人： KEITH KUNITSKY , Mukesh C. Shah , Steven W. Shuey , Mark E. Wagman
发明人： KEITH KUNITSKY , Mukesh C. Shah , Steven W. Shuey , Mark E. Wagman
IPC分类号： C08F2/00 , C07D301/02 , C07D407/02
CPC分类号： C08F12/22 , C07D303/23
摘要： It was found that glycidyloxystyrenes, including glycidyloxystyrene and substituted glycidyloxystyrene, can be synthesized from hydroxycinnamic acid or substituted hydroxycinnamic acids in a one-pot, two-step process. The substrate can be thermally decarboxylated and then without purification, reacted in the presence of a halomethyl-oxirane and a base. The resulting product can be polymerized or coppolymerized to a fully substituted product.
摘要翻译：发现缩水甘油氧基苯乙烯，包括缩水甘油氧基苯乙烯和取代的缩水甘油氧基苯乙烯，可以一锅二步法从羟基肉桂酸或取代的羟基肉桂酸合成。底物可以热脱羧，然后不经纯化，在卤代甲基 - 环氧乙烷和碱的存在下反应。所得产物可以被聚合或共聚合成完全取代的产物。

27. 发明授权

US07307061B2 β-peptoids with antimicrobial activity 有权
标题翻译：具有抗菌活性的β-拟肽
公开(公告)号：US07307061B2
公开(公告)日：2007-12-11
申请号：US11311097
申请日：2005-12-19
申请人： Steven W. Shuey , William J. Delaney , Mukesh C. Shah , Mark A. Scialdone
发明人： Steven W. Shuey , William J. Delaney , Mukesh C. Shah , Mark A. Scialdone
IPC分类号： A61K38/04
CPC分类号： A61L2/23 , A23L3/3526 , A61K38/00 , A61L2/232 , A61L2/235 , C07K5/0202
摘要： The present invention relates to beta-peptoids with antimicrobial activity. The present invention also relates to methods of producing β-peptoids. The antimicrobial β-peptoids of the invention are useful in pharmaceutical, healthcare, medical device, industrial, food, agricultural, and personal care applications.
摘要翻译：本发明涉及具有抗微生物活性的β-拟肽。本发明还涉及生产β-拟肽的方法。本发明的抗微生物β-拟肽可用于制药，保健，医疗器械，工业，食品，农业和个人护理应用。

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