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21. 发明申请

US20120265203A1 Spine Stabilization 有权
标题翻译：脊柱稳定
公开(公告)号：US20120265203A1
公开(公告)日：2012-10-18
申请号：US13086122
申请日：2011-04-13
申请人： Christopher Angelucci , Michael Black , Brian Garvey , James Himmelberger , Colm McLaughlin , Robert W. Trout
发明人： Christopher Angelucci , Michael Black , Brian Garvey , James Himmelberger , Colm McLaughlin , Robert W. Trout
IPC分类号： A61B17/80 , A61B17/66
CPC分类号： A61B17/8004 , A61B17/7059 , A61B17/8009 , A61B17/8023
摘要： A bone stabilizing plate includes two plate portions, each affixable to bones of a patient, the plate portions telescoping together with mating rails and grooves. A limiter associated with one of the plate portions sliding engages one a catch associated with the other of the plate portions, when the plate portions are telescoped together, and resists stops telescoping when the plate portions are telescoped a predetermined distance apart. Once the limiter and catch are engaged, the plate portions enable imposition of a minimum compressive force between bones connected to the plates. The limiter is resiliently positioned to deflect into a relief formed in its respective plate portion. A groove positioned proximate the catch enables free telescoping motion limited by the engagement of the catch and limiter, whereby the minimum compressive force between bones is maintained, and Wolfe's Law may apply.
摘要翻译：骨稳定板包括两个板部分，每个板部分可固定于患者的骨头，板部分与配合的轨道和凹槽一起伸缩。当板部分被伸缩在一起时，与滑板中的一个相关联的限制器与一个与另一个板部分相关联的卡扣接合，并且当板部分伸缩预定距离时，抵抗停止伸缩。一旦限制器和卡扣被接合，板部分就能够在连接到板的骨头之间施加最小的压缩力。限位器被弹性地定位成偏转成形成在其各自的板部分中的凸起。靠近捕捉器定位的凹槽能够通过捕获和限制器的啮合来限制自由伸缩运动，由此保持骨骼之间的最小压缩力，并且可以应用沃尔夫定律。

22. 发明申请

US20120065686A1 Spine Stabilization System 有权
标题翻译：脊柱稳定系统
公开(公告)号：US20120065686A1
公开(公告)日：2012-03-15
申请号：US12874845
申请日：2010-09-02
申请人： Michael Black , Michal Zentko , Jason Pastor
发明人： Michael Black , Michal Zentko , Jason Pastor
IPC分类号： A61B17/70 , A61B17/88 , A61B17/80
CPC分类号： A61B17/7044 , A61B17/7055
摘要： The present invention is directed to a spine stabilization system and method for stabilizing the spine. In particular, the present invention is directed to a spinal stabilization system having an occipital plate configured with a central portion and at least two extension portions extending from the central portion. At least two rod receivers are positioned on each one of the at least two extension portions and the at least two rod receivers are adapted and configured to receive at least two elongated rods. At least two locking assemblies are adapted and configured to retain the at least two elongated rods within the at least two rod receivers. The occipital plate further includes a plurality of holes for receiving bone fasteners and includes a slot for receiving each one of the at least two rod receivers, and the rod receivers being capable of translating and rotating within the slots.
摘要翻译：本发明涉及一种用于稳定脊柱的脊柱稳定系统和方法。特别地，本发明涉及一种脊柱稳定系统，其具有构造为具有中心部分的枕骨板和至少两个从中心部分延伸的延伸部分。至少两个杆接收器定位在所述至少两个延伸部分中的每一个上，并且所述至少两个杆接收器适于并构造成容纳至少两个细长杆。至少两个锁定组件被适配和构造成将至少两个细长杆保持在至少两个杆接收器内。枕骨板还包括用于接收骨固定件的多个孔，并且包括用于容纳所述至少两个杆接收器中的每一个的槽，并且所述杆接收器能够在槽内平移和旋转。

23. 发明申请

US20070009546A1 Purified polypeptides from streptococcus pneumoniae 失效
标题翻译：来自肺炎链球菌的纯化多肽
公开(公告)号：US20070009546A1
公开(公告)日：2007-01-11
申请号：US11403784
申请日：2006-04-13
申请人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
发明人： Michael Black , John Hodgson , David Knowles , Michael Lonetto , Richard Nicholas , Robert Stodola , Martin Burnham
IPC分类号： A61K39/02 , C07H21/04 , C12P21/06 , C12N1/21 , C07K14/315
CPC分类号： C12N9/1077 , A61K38/00 , A61K39/00 , C07K14/3156 , C07K2319/00 , C12N9/1205 , C12N9/78 , C12N9/80 , C12Y207/01002
摘要： The invention provides novel polypeptides and polynucleotides encoding such polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing such polypeptides to screen for antibacterial compounds.
摘要翻译：本发明提供了编码这种多肽的新型多肽和多核苷酸以及通过重组技术产生这种多肽的方法。还提供了利用这些多肽筛选抗菌化合物的方法。

24. 发明申请

US20050267451A1 Device for application of multiple hygienic effects 审中-公开
标题翻译：应用多种卫生效果的设备
公开(公告)号：US20050267451A1
公开(公告)日：2005-12-01
申请号：US11179445
申请日：2005-07-12
申请人： Michael Black
发明人： Michael Black
IPC分类号： A61C15/02 , A61N5/06 , A61N5/067 , A61B18/18
CPC分类号： A61N5/0603 , A61C15/02 , A61N2005/0606 , A61N2005/0609 , A61N2005/063 , A61N2005/0644 , A61N2005/0651 , A61N2005/067
摘要： A device for the application of two or more hygienic effects is provided. The device could have one element on a support (e.g. a pick or a toothpick) or multiple elements distributed on a support (a brush, a comb, a toothbrush, a glove or a facemask). In case of multiple elements, a pattern of elements could be created into a topographical surface of elements. Two or more light sources are used for each element whereby each of the light sources is capable of producing a unique light treatment. The two or more light sources could be within the element, i.e., inside or integrated in the element, or could be inside the support and then optically connected to the element.
摘要翻译：提供了一种应用两种或多种卫生效果的装置。该装置可以在支撑件（例如，拾取器或牙签）上具有一个元件或分布在支撑件（刷子，梳子，牙刷，手套或面罩）上的多个元件。在多个元素的情况下，元素的图案可以被创建到元素的地形表面中。每个元件使用两个或更多个光源，由此每个光源能够产生独特的光处理。两个或多个光源可以在元件内，即内部或集成在元件中，或者可以在支撑体内，然后光学连接到元件。

25. 发明授权

US5546214A Method and apparatus for treating a surface with a scanning laser beam having an improved intensity cross-section 失效
公开(公告)号：US5546214A
公开(公告)日：1996-08-13
申请号：US527576
申请日：1995-09-13
申请人： Michael Black , Vladimir Lemberg
发明人： Michael Black , Vladimir Lemberg
IPC分类号： A61B17/00 , A61B18/20 , G02B26/10 , G02B26/08
CPC分类号： G02B26/10 , A61B18/203 , G02B26/101 , A61B18/20 , A61B2017/00747 , A61B2018/00452 , A61B2018/2025 , A61B2018/2095 , Y10S359/90
摘要： A method and apparatus are disclosed for laser treatment of surfaces, such as tissue. In a preferred embodiment, the invention employs a unique reflective optical delivery system which produces an improved beam intensity cross-section which reduces thermal injury, increases the precision of the tissue interaction and allows the creation of craters with decreased sizes. Reflective optics provide precise, single-layer vaporization at low power levels without thermal injury to the underlying papillary dermis. Movable optical elements focus and direct the laser beam in a scanning pattern to treat a large area of the surface.

26. 发明授权

US5382986A Liquid-crystal sunglasses indicating overexposure to UV-radiation 失效
标题翻译：指示过度暴露于紫外线辐射的液晶太阳镜
公开(公告)号：US5382986A
公开(公告)日：1995-01-17
申请号：US971892
申请日：1992-11-04
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： G01J1/02 , A61N5/00 , G01J1/42 , G01J5/26 , G02C7/10
CPC分类号： G02C7/101 , G01J1/429
摘要： Liquid crystal sunglasses indicating overexposure to UV-radiation comprising a pair of liquid-crystal lenses (12 and 14) a rim (10), a bridge portion (14) which support the lenses, and a pair of temples (18 and 20) which supported by the rim. The rim (10) supports a pair of solar cells (28 and 30) and a dual-photodetector sensor (26) which can separately measure an incident UV-A radiation and a UV-B radiation and convert these radiations into electric signals. The sunglasses's rim also incorporates a microcontroller (36). The lenses have a laminated structure composed of a color mask (43), an input polarizing plate (44), a liquid crystal cell (50) sandwiched between a pair of voltage-controlled active matrices, and an output polarizing plate (46). Each active matrix consists of a plurality of sets of pixels which control the transmission of light through the respective color cells of a mosaic mask. The microcontroller also incorporates a frequency generator (104) and a memory unit. The memory stores an algorithm for calculating thresholds of UV radiation. When these thresholds are exceeded the lenses give to the wearer a warning signal either changing the color of the lenses or causing blinking.
摘要翻译：指示过度暴露于UV辐射的液晶太阳镜，包括一对液晶透镜（12和14），边缘（10），支撑透镜的桥接部分（14）和一对镜腿（18和20），其中由边缘支撑。边缘（10）支撑一对太阳能电池（28和30）和双光电检测器传感器（26），其可分别测量入射的UV-A辐射和UV-B辐射，并将这些辐射转换成电信号。太阳眼镜的边缘还包含一个微控制器（36）。透镜具有由彩色掩模（43），输入偏振片（44），夹在一对压控有源矩阵之间的液晶单元（50）和输出偏振片（46）组成的层叠结构。每个有源矩阵由多个像素集合组成，这些像素组控制通过镶嵌掩模的相应颜色单元的光的透射。微控制器还包括频率发生器（104）和存储器单元。存储器存储用于计算UV辐射阈值的算法。当超过这些阈值时，镜片给佩戴者带来改变镜片颜色或引起眨眼的警告信号。

27. 发明授权

US5382770A Mirror-based laser-processing system with visual tracking and position control of a moving laser spot 失效
标题翻译：基于镜像的激光加工系统，具有视觉跟踪和移动激光点的位置控制
公开(公告)号：US5382770A
公开(公告)日：1995-01-17
申请号：US4709
申请日：1993-01-14
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： B23K26/03 , B23K26/04 , B23K26/067 , B23K26/00
CPC分类号： B23K26/032 , B23K26/04 , B23K26/0643 , B23K26/0665 , B23K26/067
摘要： A mirror-based laser processing system, e.g., for laser welding, provided with manual control of movements of a laser welding spot W on an object O being treated. The system includes a laser source (10) which generates a laser beam capable of treating the object (O), a mirror-based micromanipulator (14) which consists of a concave mirror (18) and a convex mirror (16) facing each other, and a laser beam splitter (20) which is located on the path of the laser beam reflected from the concave mirror (18). The laser beam splitter (20) has a coating which reflects the laser beam onto the object (O), but is capable of passing visible and infrared light. Movements of the laser-beam splitter are manually controlled from an external terminal, which is made in the form of a joy stick (50). The joy stick is capable of moving the laser welding spot (W) in any direction over the object's surface in the X-Y coordinate system. Adjustment in the Z-axis direction is performed through a zoom system of the mirror-based micromanipulator (14). The infrared light which is generated by the heated area of the object passes through the laser-beam splitter which transmits visible light to the microscopic head for observation of the object and reflects the infrared light. The latter is processed by a processing unit (38) and is converted into visible thermal information presented on a display (46) in the form convenient for manual control of the position of the welding spot W.
摘要翻译：例如用于激光焊接的基于镜子的激光处理系统提供手动控制激光焊接点W在被处理物体O上的运动。该系统包括产生能够处理物体（O）的激光束的激光源（10），由面对的凹面镜（18）和凸面镜（16）构成的基于镜子的显微操纵器（14），以及位于从凹面镜（18）反射的激光束的路径上的激光分束器（20）。激光分束器（20）具有将激光束反射到物体（O）上但能够通过可见光和红外光的涂层。激光束分离器的移动由外部端子手动控制，外部端子以操纵杆（50）的形式制成。操纵杆能够在X-Y坐标系上的物体表面上以任何方向移动激光焊接点（W）。通过基于反射镜的显微操纵器（14）的变焦系统来进行Z轴方向的调整。由物体的加热区域产生的红外光通过激光束分离器，其将可见光透射到微观头以观察物体并反射红外光。后者由处理单元（38）处理，并且以便于手动控制焊接位置的位置的形式被转换成呈现在显示器（46）上的可见热信息。

28. 发明授权

US5306917A Electro-optical system for measuring and analyzing accumulated short-wave and long-wave ultraviolet radiation exposure 失效
标题翻译：用于测量和分析累积的短波和长波紫外线辐射暴露的电光系统
公开(公告)号：US5306917A
公开(公告)日：1994-04-26
申请号：US928918
申请日：1992-08-12
申请人： Michael Black , Vladimir Kupershmidt , Michael Spitkovsky
发明人： Michael Black , Vladimir Kupershmidt , Michael Spitkovsky
IPC分类号： A61B5/00 , A61B10/00 , A61N5/00 , A61N5/06 , G01J1/02 , G01J1/42 , G01W1/12 , G01J1/44
CPC分类号： G01J1/429 , A61N5/06
摘要： An electro-optical system intended for medical use that measures and analyses an individual's cumulative short-wave and long-wave UV-radiation exposure as detected by sensor 10 of the system attached to the individual. Sensor 10 separately registers sequences of UV-A and UV-B signals which are synchronized in time by clock pulses. After a predetermined interval sensor 10 is connected to an analyzer unit 12 that statistically processes the collected data to derive risk factor and generate predictive information. Such information permits the physician to predict individual-specific levels of ultraviolet (UV) radiation potentially harmful to the skin and help protect the individual from skin cancer and similar diseases with solar radiation causation.
摘要翻译：一种用于医疗用途的电光学系统，其用于测量和分析个体的累积短波和长波紫外线辐射暴露，由连接到个体的系统的传感器10检测。传感器10分别注册时钟脉冲同步的UV-A和UV-B信号序列。在将预定间隔传感器10连接到分析器单元12之后，其统计地处理收集的数据以导出风险因子并产生预测信息。这样的信息允许医师预测对皮肤有潜在危害的紫外线（UV）辐射的个体特异性水平，并且有助于保护个体免受皮肤癌和具有太阳辐射因果关系的类似疾病的影响。

29. 发明授权

US5184156A Glasses with color-switchable, multi-layered lenses 失效
标题翻译：眼镜配有可切换的多层透镜
公开(公告)号：US5184156A
公开(公告)日：1993-02-02
申请号：US789994
申请日：1991-11-12
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： G02C7/10 , G02C7/12
CPC分类号： G02C7/12 , G02C7/101
摘要： Glasses with multilayered, color-switchable lenses (102) and (104) for blocking harmful radiation include a rim (100) connected to temples (108) and (110). The rim contains a photosensor (116), a color-changing switch (118), a dry-cell power source (120), solar cells (121) and (123), an electronic driver unit (122), and an electronic circuit (124). The color-switchable lenses comprise glass plates (126a), (126b), and (126c), conductive layers (136a), (136c) (142a), and (142b), color polarizers (138a) and (136c), alignment layers (140a), (140c), (146), and (148), a neutral polarizer (144), and liquid-crystal layers (158) and (160). When the photosensor determines that the intensity of incident radiation falls above or below the specified threshold, an amplified signal is sent via the circuit to the electronic driver unit which supplies layers 158 and 160 with voltages which cause the color-switchable lenses to change their spectral transmittance characteristics.
摘要翻译：具有用于阻挡有害辐射的多层可变色透镜（102）和（104）的眼镜包括连接到镜腿（108）和（110）的边缘（100）。边缘包含光电传感器（116），变色开关（118），干电池电源（120），太阳能电池（121）和（123），电子驱动器单元（122）和电子电路（124）。可变色透镜包括玻璃板（126a），（126b）和（126c），导电层（136a），（136c）（142a）和（142b），彩色偏光器（138a）和（136c）层（140a），（140c），（146）和（148），中性偏振片（144）和液晶层（158）和（160）。当光电传感器确定入射辐射的强度高于或低于规定阈值时，放大的信号通过电路被发送到电子驱动器单元，电子驱动器单元为层158和160提供电压，使得颜色可切换透镜改变其光谱透光率特性。

30. 发明授权

US5076669A Method and apparatus for selectively blocking light beams of different wavelengths with single color-sensitive filter 失效
标题翻译：用单色敏感滤光片选择性地阻挡不同波长的光束的方法和装置
公开(公告)号：US5076669A
公开(公告)日：1991-12-31
申请号：US626307
申请日：1990-12-12
申请人： Michael Black , Vladimir Kupershmidt
发明人： Michael Black , Vladimir Kupershmidt
IPC分类号： G02F1/1335 , G02F1/23 , G03F7/20
CPC分类号： G02F1/13318 , G03F7/2057 , G02F1/133514
摘要： A method and apparatus for selectively blocking light beams of different wavelengths with the use of a single color-sensitive filter by passing the beams through a multiple layer system consisting of an input polarization plate (12), an output polarization plate (14), a liquid crystal cell (18) sandwiched between voltage-controlled matrices (20a and 20b), and a mosaic color mask (34). The incident light is detected by a photoelectronic sensor (32) which sends voltage signals to respective pixels (22) which form the above-mentioned matrices. These signals selectively control the polarization states of the beams passed through the respective pixels. Depending on the polarization states of the beams, the output polarization plate can either block the light or pass it to a color mask (34). This mask consists of a periodical set of color cells, the amount and dimensions of which correspond to those of the pixels. As a result, the mask selectively filters the beam in accordance with its pattern.
摘要翻译：一种用于通过使光束通过由输入偏振板（12），输出偏振板（14），输出偏振板（12），输出偏振板夹在电压矩阵（20a和20b）之间的液晶单元（18）和马赛克彩色掩模（34）。入射光由光电传感器（32）检测，光电传感器（32）将电压信号发送到形成上述矩阵的各个像素（22）。这些信号选择性地控制通过各个像素的光束的偏振状态。取决于光束的偏振状态，输出偏振板可以阻挡光或将其传递到彩色掩模（34）。该蒙版由一组彩色单元组成，其数量和尺寸与像素的数量和尺寸相对应。结果，掩模根据其图案选择性地过滤光束。

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