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21. 发明授权

EP2695003B1 COMPOSITION FOR FORMING A CONTACT LENS 无效
标题翻译：成分用于制造隐形眼镜
公开(公告)号：EP2695003B1
公开(公告)日：2015-03-18
申请号：EP12712260.4
申请日：2012-03-29
申请人： Novartis AG
发明人： SEIFERLING, Bernhard , SCHMIDT, Thomas , VOGT, Jürgen
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F20/56 , C08L101/14 , C08L33/26 , C08L33/10 , C08L83/04

22. 发明公开

EP1913427A1 METHOD FOR MAKING CONTACT LENSES 无效
标题翻译：制造隐形眼镜的方法
公开(公告)号：EP1913427A1
公开(公告)日：2008-04-23
申请号：EP06776745.9
申请日：2006-08-10
申请人： Novartis AG
发明人： WANG, Guigui , SMITH, Dawn , VOGT, Jürgen , LALLY, John, Martin , DEVLIN, Brian, Gerrard
IPC分类号： G02B1/04
CPC分类号： B29C33/60 , B29C33/62 , B29D11/00134 , B29D11/00192 , G02B1/043
摘要： The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a non-crosslinkable hydrophilic polymer into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the non-crosslinkable hydrophilic polymer and to provide a disparity of about 10 N or less in mold separation force. The non-crosslinkable hydrophilic polymer has a limited miscibility with the lens-forming material low enough to successfully and timely form an intact interfacial film with a sufficient thickness at an interface between the mold and the fluid composition therein, and has a structure that minimizes entanglement of the non-crosslinkable hydrophilic polymer in the interfacial film with the polymer matrix of the formed lens.
摘要翻译：本发明涉及一种用于生产具有改进的镜片质量和增加的产品产量的隐形眼镜的方法和流体组合物。本发明的方法包括将不可交联的亲水性聚合物加入包含透镜形成材料的流体组合物中，其量足以将平均的模具分离力降低至少约40％，与不含不可交联的亲水性聚合物相比聚合物并且在模具分离力中提供约10N或更小的差异。不可交联的亲水性聚合物与透镜形成材料的可混合性有限，足以在模具和其中的流体组合物之间的界面处成功且及时地形成具有足够厚度的完整界面膜，并且具有使缠结最小化的结构的界面膜中的不可交联的亲水性聚合物与所形成的镜片的聚合物基质接触。

23. 发明公开

EP0819258A1 EXTENDED WEAR OPHTHALMIC LENS 失效
标题翻译：由于长时间转让性眼用镜片
公开(公告)号：EP0819258A1
公开(公告)日：1998-01-21
申请号：EP96908116.0
申请日：1996-03-22
申请人： Novartis AG , COMMONWEALTH SCIENTIFIC AND INDUSTRIAL RESEARCH ORGANISATION
发明人： NICOLSON, Paul, Clement , BARON, Richard, Carlton , CHABRECEK, Peter , COURT, John , DOMSCHKE, Angelika , GRIESSER, Hans, Jörg , HO, Arthur , HÖPKEN, Jens , LAYCOCK, Bronwyn, Glenice , LIU, Qin , LOHMANN, Dieter , MEIJS, Gordon, Francis , PAPASPILIOTOPOULOS, Eric , RIFFLE, Judy, Smith , SCHINDHELM, Klaus , SWEENEY, Deborah , TERRY, Wilson, Leonard, Jr. , VOGT, Jürgen , WINTERTON, Lynn, Cook
IPC分类号： G02C7 , A61L27 , B29C39 , B29D11 , C08F290 , C08G18 , C08J5 , C08L33 , C08L83 , G02B1 , B29C71
CPC分类号： G02C7/049 , A61L27/26 , A61L27/34 , A61L2430/16 , B05D1/62 , B29C39/42 , B29C71/00 , B29D11/00076 , B29L2011/0041 , C08G18/10 , C08G18/4833 , C08G18/5015 , C08G18/61 , C08G18/672 , C08G18/8116 , C08G18/8175 , G02B1/043 , Y10S525/903 , Y10S525/936 , Y10S525/937 , C08L51/085 , C08L51/08 , C08L33/00 , C08L83/04 , C08L39/06 , C08G18/63 , C08G18/48
摘要： An ophthalmic lens is disclosed which is suited for extended-wear periods of at least one day on the eye without a clinically significant amount of corneal swelling and without substantial wearer discomfort. The lens has a balance of oxygen permeability and ion or water permeability, with the ion or water permeability being sufficient to provide good on-eye movement, such that a good tear exchange occurs between the lens and the eye. A preferred lens is a copolymerization product of an oxyperm macromer and an ionoperm monomer. The invention encompasses extended wear contact lenses, which include a core having oxygen transmission and ion transmission pathways extending from the inner surface to the outer surface.

25. 发明授权

EP1697112B1 METHOD FOR PRODUCING TINTED CONTACT LENSES 有权转让
标题翻译：用于生产调子隐形眼镜
公开(公告)号：EP1697112B1
公开(公告)日：2008-04-23
申请号：EP04804030.7
申请日：2004-12-17
申请人： Novartis AG
发明人： WINTERTON, Lynn, Cook , LALLY, John, Martin , VOGT, Jürgen
IPC分类号： B29D11/00 , B29C67/00
CPC分类号： B29D11/00317
摘要： The invention provides a method of producing a full-body tinted contact lens. The method of the invention comprises the steps of: preconditioning particles of a pigments; dispersing the preconditioned pigment particles in a polymerizable fluid composition to obtain a pigment-containing polymerizable dispersion; introducing an amount of the pigment-containing polymerizable dispersion in a mold for making a contact lens; polymerizing the polymerizable dispersion in the mold to form a full-body tinted contact lens with the particles of the pigment entrapped and distributed therein. In addition, the invention provides a method for preparing preconditioned pigment particles and full-body tinted contact lenses produced according the method of the invention.

26. 发明公开

EP2695003A1 COMPOSITION FOR FORMING A CONTACT LENS 无效
标题翻译：成分用于制造隐形眼镜
公开(公告)号：EP2695003A1
公开(公告)日：2014-02-12
申请号：EP12712260.4
申请日：2012-03-29
申请人： Novartis AG
发明人： SEIFERLING, Bernhard , SCHMIDT, Thomas , VOGT, Jürgen
IPC分类号： G02B1/04
CPC分类号： G02B1/043 , C08F20/56 , C08L101/14 , C08L33/26 , C08L33/10 , C08L83/04
摘要： There is described a composition for forming an contact lens, in particular for forming a silicone hydrogel contact lens, comprising at least one first vinylic monomer or macromer having one first ethylenically unsaturated group and at least one second vinylic monomer or macromer having one second ethylenically unsaturated group, wherein the first and second ethylenically unsaturated groups are different from each other and wherein the composition further comprises a crosslinker with at least two ethylenically unsaturated (polymerizable) groups with a selected kinetic copolymerization parameter η of less than 1.0 relative to one of the first and second ethylenically unsaturated (polymerizable) groups as defined above.

27. 发明授权

EP1913427B1 METHOD FOR MAKING CONTACT LENSES 无效
标题翻译：用于制造隐形眼镜
公开(公告)号：EP1913427B1
公开(公告)日：2011-04-06
申请号：EP06776745.9
申请日：2006-08-10
申请人： Novartis AG
发明人： WANG, Guigui , SMITH, Dawn , VOGT, Jürgen , LALLY, John, Martin , DEVLIN, Brian, Gerrard
IPC分类号： G02B1/04
CPC分类号： B29C33/60 , B29C33/62 , B29D11/00134 , B29D11/00192 , G02B1/043
摘要： The instant invention pertains to a method and a fluid composition for producing contact lenses with improved lens quality and with increased product yield. The method of the invention involves adding a non-crosslinkable hydrophilic polymer into a fluid composition including a lens-forming material in an amount sufficient to reduce an averaged mold separation force by at least about 40% in comparison with that without the non-crosslinkable hydrophilic polymer and to provide a disparity of about 10 N or less in mold separation force. The non-crosslinkable hydrophilic polymer has a limited miscibility with the lens-forming material low enough to successfully and timely form an intact interfacial film with a sufficient thickness at an interface between the mold and the fluid composition therein, and has a structure that minimizes entanglement of the non-crosslinkable hydrophilic polymer in the interfacial film with the polymer matrix of the formed lens.

28. 发明公开

EP2115499A2 METHOD FOR IMPARTING HYDROGEL CONTACT LENSES WITH DESIRED PROPERTIES 有权转让
标题翻译：设备从具有所需特性的水凝胶隐形眼镜的方法
公开(公告)号：EP2115499A2
公开(公告)日：2009-11-11
申请号：EP08841458.6
申请日：2008-02-22
申请人： Novartis AG
发明人： QIU, Yongxing , VOGT, Jürgen , LALLY, John Martin
IPC分类号： G02B1/04 , B29D11/00
CPC分类号： B29D11/00067 , G02B1/043 , C08L83/04
摘要： A cost-effective method for making hydrogel contact lenses with desired properties, such as antimicrobial property and/or increased surface hydrophilicity. The method comprises a step of contacting a dry or unhydrated hydrogel contact lens with an aqueous solution (or hydrating solution) containing silver nanoparticles and/or a lubricant or wetting agent. By using a method of the invention, resultant hydrogel contact lenses can have antimicrobial capability and/or enhanced lens wearer's comfort.

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