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21. 发明申请

US20100047901A1 SYSTEM AND METHOD FOR ELECTRONIC SENSING OF BIOMOLECULES 审中-公开
标题翻译：电子感应生物分子的系统和方法
公开(公告)号：US20100047901A1
公开(公告)日：2010-02-25
申请号：US12607912
申请日：2009-10-28
申请人： Keith Bradley , Jean-Christophe P. Gabriel , George Grüner , Alexander Star , Eugene Tu , Christian Valcke
发明人： Keith Bradley , Jean-Christophe P. Gabriel , George Grüner , Alexander Star , Eugene Tu , Christian Valcke
IPC分类号： G01N33/53
CPC分类号： B82Y30/00 , B01L3/50857 , B01L2300/0636 , B01L2300/0663 , B01L2300/0819 , B01L2300/0851 , B01L2300/0893 , B01L2300/0896 , B01L2300/16 , B82Y10/00 , G01N33/5438 , G01N33/551 , G01N33/566 , G01N33/582
摘要： A nanoelectronic device is combined with a cellular membrane component to provide a sensor for biomolecules or to provide information about the structure of the membrane. The nanoelectronic device may comprise a network of randomly-oriented nanotubes, or other nanostructure, arranged on a substrate with adjacent electrodes so as to operate as a field-effect transistor sensor or as a capacitive sensor. A cellular membrane is disposed over the nanostructure element.
摘要翻译：纳米电子器件与细胞膜组件组合以提供用于生物分子的传感器或提供关于膜结构的信息。纳米电子器件可以包括布置在具有相邻电极的衬底上的随机取向的纳米管或其他纳米结构的网络，以便作为场效应晶体管传感器或电容式传感器工作。细胞膜设置在纳米结构元件上。

22. 发明授权

US07714398B2 Nanoelectronic measurement system for physiologic gases and improved nanosensor for carbon dioxide 有权
标题翻译：用于生理气体的纳米电子测量系统和改进的二氧化碳纳米传感器
公开(公告)号：US07714398B2
公开(公告)日：2010-05-11
申请号：US11390493
申请日：2006-03-27
申请人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
发明人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
IPC分类号： G01N27/414
CPC分类号： G01N33/5438 , A61B5/073 , A61B2562/0285 , B82Y10/00 , B82Y15/00 , B82Y20/00 , H01L51/0048 , H01L51/0052 , H01L51/0545
摘要： A system for measuring an analyte of interest, particularly carbon dioxide, dissolved in a fluid media of a patient including a nanoelectronic sensor and a measurement instrument in communication with the sensor and configured to receive at least a signal from the sensor indicative of a response of the sensor to at least the analyte of interest.
摘要翻译：一种用于测量感兴趣的分析物，特别是二氧化碳的系统，其溶解在患者的流体介质中，包括与所述传感器通信的纳米电子传感器和测量仪器，并且被配置为从所述传感器接收表示响应的信号传感器至少是所关注的分析物。

23. 发明申请

US20100056892A1 NANOELECTRONIC MEASUREMENT SYSTEM FOR PHYSIOLOGIC GASES AND IMPROVED NANOSENSOR FOR CARBON DIOXIDE 有权
标题翻译：用于生物气体的纳米电子测量系统和改进的二氧化碳纳米传感器
公开(公告)号：US20100056892A1
公开(公告)日：2010-03-04
申请号：US11390493
申请日：2006-03-27
申请人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
发明人： Nadav Ben-Barak , Daniel M. Chang , Jean-Christophe P. Gabriel , Vikram Joshi , Joseph Niemann , Alexander Star , Christian Valcke
IPC分类号： A61B5/05 , A61N1/36
CPC分类号： G01N33/5438 , A61B5/073 , A61B2562/0285 , B82Y10/00 , B82Y15/00 , B82Y20/00 , H01L51/0048 , H01L51/0052 , H01L51/0545
摘要： A system for measuring an analyte of interest, particularly carbon dioxide, dissolved in a fluid media of a patient including a nanoelectronic sensor and a measurement instrument in communication with the sensor and configured to receive at least a signal from the sensor indicative of a response of the sensor to at least the analyte of interest.
摘要翻译：一种用于测量感兴趣的分析物，特别是二氧化碳的系统，其溶解在患者的流体介质中，包括与所述传感器通信的纳米电子传感器和测量仪器，并且被配置为从所述传感器接收表示响应的信号传感器至少是所关注的分析物。

24. 发明申请

US20100282245A1 Detection of nitric oxide 审中-公开
标题翻译：检测一氧化氮
公开(公告)号：US20100282245A1
公开(公告)日：2010-11-11
申请号：US12008800
申请日：2008-01-14
申请人： Alexander Star , Oleksander Kuzmych
发明人： Alexander Star , Oleksander Kuzmych
IPC分类号： A61M11/00 , G01N33/497 , G01N33/00
CPC分类号： G01N27/4146 , A61B5/082 , A61B5/087 , G01N33/0037 , G01N33/004 , G01N33/006 , G01N33/497 , Y02A50/245 , Y10T436/177692
摘要： A system for the detection of nitric oxide in a gas sample includes a converter for oxidation of nitric oxide to nitrogen dioxide, a nitrogen dioxide sensor including nanostructures and a filtering device to remove at least carbon dioxide from the gas sample positioned upstream of the converter. The nitrogen dioxide sensor can, for example, include a recognition layer on the nanostructures adapted to enhance sensitivity to nitrogen dioxide. A method for detecting nitric oxide in exhaled breath includes detecting nitric oxide in the exhaled breath using a nitric oxide sensor including nanostructures. Another method for detecting nitric oxide in exhaled breath includes filtering the breath to remove at least carbon dioxide from the breath, oxidizing nitric oxide in the exhaled breath to nitrogen dioxide and detecting the nitrogen dioxide using a nitrogen dioxide sensor including nanostructures.
摘要翻译：用于检测气体样品中的一氧化氮的系统包括用于将一氧化氮氧化成二氧化氮的转化器，包含纳米结构的二氧化氮传感器和用于从位于转化器上游的气体样品中去除至少二氧化碳的过滤装置。例如，二氧化氮气体传感器可以包括适于增强对二氧化氮敏感性的纳米结构上的识别层。用于检测呼出呼吸中的一氧化氮的方法包括使用包括纳米结构的一氧化氮传感器检测呼出气中的一氧化氮。用于检测呼出呼吸中的一氧化氮的另一种方法包括过滤呼吸以从呼吸中去除至少二氧化碳，将呼出的呼吸中的一氧化氮氧化成二氧化氮，并使用包括纳米结构的二氧化氮传感器检测二氧化氮。

25. 发明申请

US20100137731A1 NANOELECTRONIC CAPNOMETER ADAPTER INCLUDING A NANOELECTRONIC SENSOR SELECTIVELY SENSITIVE TO AT LEAST ONE GASEOUS CONSITUTENT OF EXHALED BREATH 审中-公开
标题翻译：包含纳米电子传感器的纳米电容式调节器适配器选择性地至少可以将一次气体渗透到呼吸道中
公开(公告)号：US20100137731A1
公开(公告)日：2010-06-03
申请号：US12485793
申请日：2009-06-16
申请人： Alexander Star , Jeffery Wyatt , Vikram Joshi , Joseph R. Stetter , George Gruner
发明人： Alexander Star , Jeffery Wyatt , Vikram Joshi , Joseph R. Stetter , George Gruner
IPC分类号： A61B5/08
CPC分类号： G01N33/497 , B82Y10/00 , G01N27/4141 , G01N27/4146 , Y10S977/72
摘要： A capnometer adaptor includes a nanostructure sensor configured to selectively respond to a gaseous constituent of exhaled breath, such as to carbon dioxide. In certain embodiments, the adaptor includes an airway adaptor having at least one channel configured for the passage of respiratory gas; at least one nanostructure sensor in fluid communication with the passage, the sensor configured to selectively respond to at least one gaseous constituent of exhaled breath comprising carbon dioxide; and electronic hardware connected to the nanostructure sensor and configured to provide a signal indicative of a response of the sensor to the at least one gaseous constituent of exhaled breath. The sensor may be provided as a compact and solid-state device, and may be adapted for a variety of respiratory monitoring applications.
摘要翻译：电导率计适配器包括纳米结构传感器，其被配置为选择性地响应呼出气体的气体成分，例如二氧化碳。在某些实施例中，适配器包括气道适配器，其具有构造成用于呼吸气体通过的至少一个通道; 至少一个与所述通道流体连通的纳米结构传感器，所述传感器被配置为选择性地响应包含二氧化碳的呼出气体的至少一种气体成分; 以及连接到纳米结构传感器并被配置为提供指示传感器对呼出气体的至少一种气体成分的响应的信号的电子硬件。传感器可以被提供为紧凑和固态设备，并且可以适用于各种呼吸监测应用。

26. 发明授权

US07547931B2 Nanoelectronic capnometer adaptor including a nanoelectric sensor selectively sensitive to at least one gaseous constituent of exhaled breath 失效
标题翻译：包括纳米电传感器的纳米电子测温仪适配器，其选择性地对呼出气体的至少一种气体成分敏感
公开(公告)号：US07547931B2
公开(公告)日：2009-06-16
申请号：US11019792
申请日：2004-12-20
申请人： Alexander Star , Jeffrey Wyatt , Vikram Joshi , Joseph R. Stetter , George Grüner
发明人： Alexander Star , Jeffrey Wyatt , Vikram Joshi , Joseph R. Stetter , George Grüner
IPC分类号： G01N1/00
CPC分类号： G01N33/497 , B82Y10/00 , G01N27/4141 , G01N27/4146 , Y10S977/72
摘要： A capnometer adaptor includes a nanostructure sensor configured to selectively respond to a gaseous constituent of exhaled breath, such as to carbon dioxide. In certain embodiments, the adaptor includes an airway adaptor having at least one channel configured for the passage of respiratory gas; at least one nanostructure sensor in fluid communication with the passage, the sensor configured to selectively respond to at least one gaseous constituent of exhaled breath comprising carbon dioxide; and electronic hardware connected to the nanostructure sensor and configured to provide a signal indicative of a response of the sensor to the at least one gaseous constituent of exhaled breath. The sensor may be provided as a compact and solid-state device, and may be adapted for a variety of respiratory monitoring applications.
摘要翻译：电导率计适配器包括纳米结构传感器，其被配置为选择性地响应呼出气体的气体成分，例如二氧化碳。在某些实施例中，适配器包括气道适配器，其具有构造成用于呼吸气体通过的至少一个通道; 至少一个与所述通道流体连通的纳米结构传感器，所述传感器被配置为选择性地响应包含二氧化碳的呼出气体的至少一种气体成分; 以及连接到纳米结构传感器并被配置为提供指示传感器对呼出气体的至少一种气体成分的响应的信号的电子硬件。传感器可以被提供为紧凑和固态设备，并且可以适用于各种呼吸监测应用。

27. 发明申请

US20090101996A1 NANOSTRUCTURES WITH ELECTRODEPOSITED NANOPARTICLES 审中-公开
标题翻译：具有电沉积纳米颗粒的纳米结构
公开(公告)号：US20090101996A1
公开(公告)日：2009-04-23
申请号：US12268327
申请日：2008-11-10
申请人： Keith BRADLEY , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
发明人： Keith BRADLEY , Alona J. Davis , Jean-Christophe P. Gabriel , Tzong-Ru Han , Vikram Joshi , Alexander Star
IPC分类号： G01N27/403 , H01L21/288
CPC分类号： B82Y30/00 , C25D3/12 , C25D3/46 , C25D3/48 , C25D3/50 , C25D5/02 , C25D5/10 , C25D5/54 , C25D17/005 , C25D21/12 , G01N27/4146 , G01N33/005 , Y10S977/72
摘要： A nanoelectronic device includes a nanostructure, such as a nanotube or network of nanotube, disposed on a substrate. Nanoparticles are disposed on or adjacent to the nanostructure so as to operatively effect the electrical properties of the nanostructure. The nanoparticles may be composed of metals, metal oxides or salts and nanoparticles composed of different materials may be present. The amount of nanoparticles may be controlled to preserve semiconductive properties of the nanostructure, and the substrate immediately adjacent to the nanostructure may remain substantially free of nanoparticles. A method for fabricating the device includes electrodeposition of the nanoparticles using one of more solutions of dissolved ions while providing an electric current to the nanostructures but not to the surrounding substrate.
摘要翻译：纳米电子器件包括纳米结构，例如纳米管或纳米管网络，其设置在衬底上。将纳米颗粒设置在纳米结构上或与纳米结构相邻，以便有效地影响纳米结构的电性能。纳米颗粒可以由金属，金属氧化物或盐组成，并且可以存在由不同材料组成的纳米颗粒。可以控制纳米颗粒的量以保持纳米结构的半导体性质，并且紧邻纳米结构的衬底可以基本上不含纳米颗粒。制造该器件的方法包括使用溶解离子的更多溶液中的一种电解沉积纳米颗粒，同时向纳米结构提供电流，但不向周围衬底提供电流。

28. 发明申请

US20140318990A1 pH SENSOR SYSTEM AND METHODS OF SENSING pH 审中-公开
标题翻译： pH传感器系统和感测方法pH值
公开(公告)号：US20140318990A1
公开(公告)日：2014-10-30
申请号：US14232138
申请日：2012-07-11
申请人： Alexander Star
发明人： Alexander Star
IPC分类号： G01N27/414
CPC分类号： G01N27/4146 , B82Y15/00 , B82Y30/00 , B82Y99/00 , G01N21/80 , G01N27/128 , Y10S977/75 , Y10S977/773 , Y10S977/902
摘要： A system for measuring pH includes a substrate and a sensor medium on the substrate. The sensor medium includes at least one oxidized carbon nanostructure and optionally at least one composition immobilized on the at least one oxidized carbon nanostructure. The at least one composition has at least one property that depends on pH. The system further includes at least one measurement system to measure a property of the sensor medium.
摘要翻译：用于测量pH的系统包括衬底和衬底上的传感器介质。传感器介质包括至少一个氧化的碳纳米结构和任选的固定在至少一个氧化的碳纳米结构上的至少一种组合物。至少一种组合物具有取决于pH的至少一种性质。该系统还包括至少一个测量传感器介质性质的测量系统。

29. 发明授权

US08530227B2 Degradation of nanomaterials 有权
标题翻译：纳米材料降解
公开(公告)号：US08530227B2
公开(公告)日：2013-09-10
申请号：US12603104
申请日：2009-10-21
申请人： Alexander Star , Valerian E. Kagan , Brett Lee Allen
发明人： Alexander Star , Valerian E. Kagan , Brett Lee Allen
IPC分类号： C12S99/00 , A62D3/02
CPC分类号： A62D3/02 , A62D3/38 , A62D2101/20 , A62D2203/04
摘要： A method of degrading carbon nanomaterials includes mixing the carbon nanomaterials with a composition comprising a peroxide substrate and at least one catalyst selected from the group of an enzyme and an enzyme analog. The peroxide substrate undergoes a reaction in the presence of the catalyst to produce an agent interactive with the nanotubes to degrade the carbon nanomaterials. The peroxide substrate can, for example, be hydrogen peroxide or an organic peroxide.
摘要翻译：降低碳纳米材料的方法包括将碳纳米材料与包含过氧化物底物和至少一种选自酶和类似物的催化剂的组合物混合。过氧化物底物在催化剂的存在下进行反应以产生与纳米管相互作用的试剂以降解碳纳米材料。过氧化物底物可以是例如过氧化氢或有机过氧化物。

30. 发明申请

US20110127446A1 NANOSTRUCTURE SYSTEMS AND METHODS FOR SENSING AN ANALYTE 审中-公开
标题翻译：用于感测分析仪的纳米结构系统和方法
公开(公告)号：US20110127446A1
公开(公告)日：2011-06-02
申请号：US12784949
申请日：2010-05-21
申请人： Alexander Star , Stephane Petoud , Douglas R. Kauffman , Chad Michael Shad , Hyounsoo Uh
发明人： Alexander Star , Stephane Petoud , Douglas R. Kauffman , Chad Michael Shad , Hyounsoo Uh
IPC分类号： G01J1/58 , G03C1/00
CPC分类号： G01N21/77 , G01N27/4146
摘要： A method of detecting an analyte in an environment, includes immobilizing at least one photoactive composition on nanostructures, the photoactive composition exhibiting emission that is sensitive to the analyte; applying electromagnetic radiation to the immobilized photoactive moiety for a period of time; measuring at least one response; and using the measured response to determine the presence the analyte in the environment. The nanostructures can, for example, include carbon nanostructures. In a number of embodiments, the analyte is oxygen.
摘要翻译：检测环境中的分析物的方法包括将至少一种光活性组合物固定在纳米结构上，所述光活性组合物显示对分析物敏感的发射; 对固定的光活性部分施加电磁辐射一段时间; 测量至少一个响应; 并使用测量的响应来确定分析物在环境中的存在。纳米结构例如可以包括碳纳米结构。在多个实施方案中，分析物是氧。

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