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21. 发明授权

US09170154B2 Data validation and classification in optical analysis systems 有权
标题翻译：光学分析系统中的数据验证和分类
公开(公告)号：US09170154B2
公开(公告)日：2015-10-27
申请号：US12295631
申请日：2007-06-26
申请人： Michael L. Myrick , Ryan J. Priore , Robert P. Freese , John C. Blackburn
发明人： Michael L. Myrick , Ryan J. Priore , Robert P. Freese , John C. Blackburn
IPC分类号： G06N5/00 , G06F1/00 , G01J3/28 , G01J3/02 , G01J3/10 , G01J3/12
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0291 , G01J3/10 , G01J2003/1213 , G01J2003/2866 , G01N2201/129
摘要： A method of classifying information in an optical analysis system includes obtaining calibration data defining a plurality of data points, each data point representing values for two or more detectors when sampling a material used to construct a multivariate optical element. Based on the calibration data, one or more validation models can be developed to indicate one or more ranges of expected results. Validation data comprising the models can be used to compare data points representing values for two or more detectors when performing a measurement of a material to determine if the data points fall within an expected range. Classification data can be generated based on the comparison and, in some embodiments, one or more indicators, such as a confidence level in a measurement, can be provided.
摘要翻译：在光学分析系统中对信息进行分类的方法包括：获取定义多个数据点的校准数据，当对用于构造多变量光学元件的材料进行采样时，每个数据点表示两个或更多个检测器的值。基于校准数据，可以开发一个或多个验证模型来指示预期结果的一个或多个范围。包括模型的验证数据可以用于比较在进行材料测量时确定两个或多个检测器的值的数据点，以确定数据点是否落在预期范围内。可以基于比较来生成分类数据，并且在一些实施例中，可以提供一个或多个指标，例如测量中的置信水平。

22. 发明授权

US07920258B2 Optical analysis system and elements to isolate spectral region 有权
标题翻译：光学分析系统和元素隔离光谱区域
公开(公告)号：US07920258B2
公开(公告)日：2011-04-05
申请号：US12094475
申请日：2006-11-27
申请人： Michael L. Myrick , Robert P. Freese , Luisa T. M. Profeta , Jonathan H. James , John C. Blackburn , Ryan J. Priore
发明人： Michael L. Myrick , Robert P. Freese , Luisa T. M. Profeta , Jonathan H. James , John C. Blackburn , Ryan J. Priore
IPC分类号： G01J3/40
CPC分类号： G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/0232 , G01J3/0291 , G01J3/08 , G01J3/28 , G01J3/36 , G01N21/274 , G01N21/35 , G01N21/3504 , G01N21/3563 , G01N21/3577
摘要： A method of selecting components for a multivariate optical computing and analysis system to isolate a spectral region includes selecting a spectral region of interest; selecting a spectral element with a predetermined transmission characteristic to control a spectral range of an illumination source; illuminating a sample with the illumination source; and analyzing an optical frequency returned by the sample relative to the spectral region of interest.
摘要翻译：选择用于多变量光学计算和分析系统以分离光谱区域的组件的方法包括选择感兴趣的光谱区域; 选择具有预定传输特性的频谱元件以控制照明源的光谱范围; 用照明源照射样品; 以及分析由样本相对于感兴趣的光谱区返回的光频率。

23. 发明授权

US07911605B2 Multivariate optical elements for optical analysis system 有权
标题翻译：用于光学分析系统的多元光学元件
公开(公告)号：US07911605B2
公开(公告)日：2011-03-22
申请号：US12094471
申请日：2006-11-27
申请人： Michael L. Myrick , Robert P. Freese , Jonathan H. James , Ryan J. Priore , John C. Blackburn
发明人： Michael L. Myrick , Robert P. Freese , Jonathan H. James , Ryan J. Priore , John C. Blackburn
IPC分类号： G01J3/40 , G02B5/22
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/0232 , G01J3/0291 , G01J3/08
摘要： A method of developing a multivariate optical element for an optical analysis system includes forming an optically absorptive spectral element having an optically absorptive material, the optically absorptive material being absorbing in a predetermined spectral region; and utilizing the optically absorptive spectral element in the optical analysis system.
摘要翻译：开发用于光学分析系统的多元光学元件的方法包括形成具有光学吸收材料的光吸收光谱元件，光学吸收材料在预定光谱区域中吸收; 并利用光学分析系统中的光吸收光谱元件。

24. 发明授权

US08049881B2 Optical analysis system and methods for operating multivariate optical elements in a normal incidence orientation 有权
标题翻译：用于在正常入射方向操作多元光学元件的光学分析系统和方法
公开(公告)号：US08049881B2
公开(公告)日：2011-11-01
申请号：US12094469
申请日：2006-11-27
申请人： Michael L. Myrick , Robert P. Freese , John C. Blackburn , Ryan J. Priore
发明人： Michael L. Myrick , Robert P. Freese , John C. Blackburn , Ryan J. Priore
IPC分类号： G01J3/40
CPC分类号： G01J3/08 , A61K8/046 , A61K8/25 , A61K8/26 , A61K8/44 , A61Q11/00 , G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/0232 , G01J3/0291 , G01J3/28 , G01N21/274 , G01N21/31
摘要： A method of arranging and utilizing a multivariate optical computing and analysis system includes transmitting light from a light source; reflecting the light from the sample; directing a portion of the light reflected from the sample with a beamsplitter; and arranging an optical filter mechanism in a normal incidence orientation to receive the light reflected from the sample, the optical filter mechanism configured to filter and measure data carried by the light reflected from the sample.
摘要翻译：一种布置和利用多变量光学计算和分析系统的方法，包括从光源发射光; 反映样品的光; 用分束器引导从样品反射的一部分光; 以及将法兰入射方向的滤光器机构布置成接收从样品反射的光，所述滤光器机构被配置为过滤和测量由样品反射的光携带的数据。

25. 发明申请

US20090299946A1 DATA VALIDATION AND CLASSIFICATION IN OPTICAL ANALYSIS SYSTEMS 有权
标题翻译：光学分析系统中的数据验证和分类
公开(公告)号：US20090299946A1
公开(公告)日：2009-12-03
申请号：US12295631
申请日：2007-06-26
申请人： Michael L. Myrick , Ryan J. Priore , Robert P. Freese , John C. Blackburn
发明人： Michael L. Myrick , Ryan J. Priore , Robert P. Freese , John C. Blackburn
IPC分类号： G06N5/02
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0291 , G01J3/10 , G01J2003/1213 , G01J2003/2866 , G01N2201/129
摘要： A method of classifying information in an optical analysis system includes obtaining calibration data defining a plurality of data points, each data point representing values for two or more detectors when sampling a material used to construct a multivariate optical element. Based on the calibration data, one or more validation models can be developed to indicate one or more ranges of expected results. Validation data comprising the models can be used to compare data points representing values for two or more detectors when performing a measurement of a material to determine if the data points fall within an expected range. Classification data can be generated based on the comparison and, in some embodiments, one or more indicators, such as a confidence level in a measurement, can be provided.
摘要翻译：在光学分析系统中对信息进行分类的方法包括：获取定义多个数据点的校准数据，当对用于构造多变量光学元件的材料进行采样时，每个数据点表示两个或更多个检测器的值。基于校准数据，可以开发一个或多个验证模型来指示预期结果的一个或多个范围。包括模型的验证数据可以用于比较在进行材料测量时确定两个或多个检测器的值的数据点，以确定数据点是否落在预期范围内。可以基于比较来生成分类数据，并且在一些实施例中，可以提供一个或多个指标，例如测量中的置信水平。

26. 发明申请

US20090216504A1 SELECTING SPECTRAL ELEMENTS AND COMPONENTS FOR OPTICAL ANALYSIS SYSTEMS 有权
标题翻译：选择光谱分析系统的光谱元素和组件
公开(公告)号：US20090216504A1
公开(公告)日：2009-08-27
申请号：US12094466
申请日：2006-11-27
申请人： Ryan J. Priore , Robert P. Freese , Michael L. Myrick , John C. Blackburn
发明人： Ryan J. Priore , Robert P. Freese , Michael L. Myrick , John C. Blackburn
IPC分类号： G01J3/06 , G06F15/00
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0232 , G01J3/0286 , G01J3/0291 , G01J3/08 , G01N21/274 , G01N21/31 , G06F17/18 , G06F17/50 , G06F17/5009 , G06F17/5086
摘要： Methods of selecting spectral elements and system components for a multivariate optical analysis system include providing spectral calibration data for a sample of interest; identifying a plurality of combinations of system components; modeling performance of a pilot system with one of the combinations of system components; determining optimal characteristics of the pilot system; and selecting optimal system components from among the combinations of system components.
摘要翻译：为多变量光学分析系统选择光谱元素和系统组件的方法包括为感兴趣的样本提供光谱校准数据; 识别系统组件的多个组合; 具有系统组件组合之一的导频系统的建模性能; 确定导频系统的最优特性; 并从系统组件的组合中选择最佳系统组件。

27. 发明申请

US20090073433A1 OPTICAL ANALYSIS SYSTEM AND METHODS FOR OPERATING MULTIVARIATE OPTICAL ELEMENTS IN A NORMAL INCIDENCE ORIENTATION 有权
标题翻译：光学分析系统和在正常入射方向上操作多种光学元件的方法
公开(公告)号：US20090073433A1
公开(公告)日：2009-03-19
申请号：US12094469
申请日：2006-11-27
申请人： Michael L. Myrick , Robert P. Freese , John C. Blackburn , Ryan J. Priore
发明人： Michael L. Myrick , Robert P. Freese , John C. Blackburn , Ryan J. Priore
IPC分类号： G01J3/36
CPC分类号： G01J3/08 , A61K8/046 , A61K8/25 , A61K8/26 , A61K8/44 , A61Q11/00 , G01J3/02 , G01J3/0205 , G01J3/021 , G01J3/0232 , G01J3/0291 , G01J3/28 , G01N21/274 , G01N21/31
摘要： A method of arranging and utilizing a multivariate optical computing and analysis system includes transmitting a o first light from a light source; generating a second light by reflecting the first light from the sample; directing a portion of the second light with a beamsplitter; and arranging an optical filter mechanism in a normal incidence orientation to receive the portion of the second light, the optical filter mechanism being configured to optically filter data carried by the portion of the second light.
摘要翻译：一种布置和利用多变量光学计算和分析系统的方法包括从光源发射第一光; 通过反射来自样品的第一光产生第二光; 用分束器引导第二光的一部分; 以及将法兰入射方向的滤光器机构布置成接收第二光的一部分，所述光学滤光器机构被配置为光学地过滤由所述第二光的一部分携带的数据。

28. 发明授权

US08862445B2 Selecting spectral elements and components for optical analysis systems 有权
标题翻译：选择光学分析系统的光谱元素和组件
公开(公告)号：US08862445B2
公开(公告)日：2014-10-14
申请号：US12094466
申请日：2006-11-27
申请人： Ryan J. Priore , Robert P. Freese , Michael L. Myrick , John C. Blackburn
发明人： Ryan J. Priore , Robert P. Freese , Michael L. Myrick , John C. Blackburn
IPC分类号： G06F7/60 , G06F17/10 , G06G7/48 , G06F17/50 , G01N21/27 , G01J3/08 , G01J3/02 , G01N21/31 , G01J3/28 , G06F17/18
CPC分类号： G01J3/28 , G01J3/02 , G01J3/0208 , G01J3/021 , G01J3/0232 , G01J3/0286 , G01J3/0291 , G01J3/08 , G01N21/274 , G01N21/31 , G06F17/18 , G06F17/50 , G06F17/5009 , G06F17/5086
摘要： Methods of selecting spectral elements and system components for a multivariate optical analysis system include providing spectral calibration data for a sample of interest; identifying a plurality of combinations of system components; modeling performance of a pilot system with one of the combinations of system components; determining optimal characteristics of the pilot system; and selecting optimal system components from among the combinations of system components.
摘要翻译：为多变量光学分析系统选择光谱元素和系统组件的方法包括为感兴趣的样本提供光谱校准数据; 识别系统组件的多个组合; 具有系统组件组合之一的导频系统的建模性能; 确定导频系统的最优特性; 并从系统组件的组合中选择最佳系统组件。

29. 发明授权

US07834999B2 Optical analysis system and optical train 有权
标题翻译：光学分析系统和光学列车
公开(公告)号：US07834999B2
公开(公告)日：2010-11-16
申请号：US12094467
申请日：2006-11-27
申请人： Michael L. Myrick , Jonathan H. James , John C. Blackburn , Robert P. Freese
发明人： Michael L. Myrick , Jonathan H. James , John C. Blackburn , Robert P. Freese
IPC分类号： G01J3/40
CPC分类号： G06E3/001
摘要： A multivariate optical computing and analysis system includes a light source configured to radiate a first light along a first ray path; a modulator disposed in the first ray path, the modulator configured to modulate the first light to a desired frequency; a spectral element disposed proximate the modulator, the spectral element configured to filter the first light for a spectral range of interest of a sample; a cavity disposed in communication with the spectral element, the cavity configured to direct the first light in a direction of the sample; a tube disposed proximate the cavity, the tube configured to receive and direct a second light generated by a reflection of the first light from the sample, the tube being further configured to separate the first and second lights; a beamsplitter configured to split the second light into a first beam and a second beam; an optical filter mechanism disposed to receive the first beam, the optical filter mechanism configured to optically filter data carried by the first beam into at least one orthogonal component of the first beam; and a detector mechanism in communication with the optical filter mechanism to measure a property of the orthogonal component to measure the data.
摘要翻译：多变量光学计算和分析系统包括配置成沿第一射线路径辐射第一光的光源; 调制器，设置在第一射线路径中，调制器被配置为将第一光调制到期望的频率; 设置在所述调制器附近的光谱元件，所述光谱元件被配置为过滤所述第一光以获得样品的感兴趣的光谱范围; 设置成与所述光谱元件连通的空腔，所述空腔被配置为沿所述样品的方向引导所述第一光; 管，其设置在所述空腔附近，所述管被配置为接收和引导由来自所述样品的所述第一光的反射产生的第二光，所述管还被配置为分离所述第一和第二光; 分束器，被配置为将所述第二光分成第一光束和第二光束; 滤光器机构，设置成接收第一光束，滤光器机构被配置为将由第一光束承载的数据光学滤波成第一光束的至少一个正交分量; 以及与光学滤波器机构通信以测量正交分量的特性以测量数据的检测器机构。

30. 发明申请

US20090219597A1 OPTICAL ANALYSIS SYSTEM AND OPTICAL TRAIN 有权
标题翻译：光学分析系统和光学火车
公开(公告)号：US20090219597A1
公开(公告)日：2009-09-03
申请号：US12094467
申请日：2006-11-27
申请人： Michael L. Myrick , Jonathan H. James , John C. Blackburn , Robert P. Freese
发明人： Michael L. Myrick , Jonathan H. James , John C. Blackburn , Robert P. Freese
IPC分类号： G06E3/00
CPC分类号： G06E3/001
摘要： A multivariate optical computing and analysis system includes a light source configured to radiate a first light along a first ray path; a modulator disposed in the first ray path, the modulator configured to modulate the first light to a desired frequency; a spectral element disposed proximate the modulator, the spectral element configured to filter the first light for a spectral range of interest of a sample; a cavity disposed in communication with the spectral element, the cavity configured to direct the first light in a direction of the sample; a tube disposed proximate the cavity, the tube configured to receive and direct a second light generated by a reflection of the first light from the sample, the tube being further configured to separate the first and second lights; a beamsplitter configured to split the second light into a first beam and a second beam; an optical filter mechanism disposed to receive the first beam, the optical filter mechanism configured to optically filter data carried by the first beam into at least one orthogonal component of the first beam; and a detector mechanism in communication with the optical filter mechanism to measure a property of the orthogonal component to measure the data.
摘要翻译：多变量光学计算和分析系统包括配置成沿第一射线路径辐射第一光的光源; 调制器，设置在第一射线路径中，调制器被配置为将第一光调制到期望的频率; 设置在所述调制器附近的光谱元件，所述光谱元件被配置为过滤所述第一光以获得样品的感兴趣的光谱范围; 设置成与所述光谱元件连通的空腔，所述空腔被配置为沿所述样品的方向引导所述第一光; 管，其设置在所述空腔附近，所述管被配置为接收和引导由来自所述样品的所述第一光的反射产生的第二光，所述管还被配置为分离所述第一和第二光; 分束器，被配置为将所述第二光分成第一光束和第二光束; 滤光器机构，设置成接收第一光束，滤光器机构被配置为将由第一光束承载的数据光学滤波成第一光束的至少一个正交分量; 以及与光学滤波器机构通信以测量正交分量的特性以测量数据的检测器机构。

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