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21. 发明申请

US20050285284A1 Synthesis of ansa-metallocenes and their parent ligands in high yield 有权
标题翻译：以高产量合成了金属茂及其母体配体
公开(公告)号：US20050285284A1
公开(公告)日：2005-12-29
申请号：US10876948
申请日：2004-06-25
申请人： Matthew Thorn , Joel Martin , Qing Yang , Albert Masino
发明人： Matthew Thorn , Joel Martin , Qing Yang , Albert Masino
IPC分类号： C07C15/067 , C07F1/02 , C07F17/00
CPC分类号： C07F17/00 , B01J31/00 , C07C2/72
摘要： The present invention provides a method of making compounds comprising linked cyclopentadienyl and fluorenyl groups, including substituted analogs thereof, which are precursors to ansa-metallocenes comprising bridged cyclopentadienyl and fluorenyl ligands. In one aspect, this invention provides a preparative method for (5-cyclopentadienyl)[5-(2,7-di-tert-butylfluorenyl)]hex-1-ene, and ansa-metallocenes comprising this ligand.
摘要翻译：本发明提供了制备包含连接的环戊二烯基和芴基（包括其取代的类似物）的化合物的方法，其是包含桥连环戊二烯基和芴基配体的ansa-金属茂的前体。一方面，本发明提供了（5-环戊二烯基）[5-（2,7-二叔丁基芴基）]己-1-烯的制备方法和包含该配体的仲 - 金属茂。

22. 发明申请

US20060287447A1 Organometal compound catalyst 有权
公开(公告)号：US20060287447A1
公开(公告)日：2006-12-21
申请号：US11019817
申请日：2004-12-21
申请人： Youlu Yu , Max MacDaniel , Kathy Collins , Gil Hawley , Michael Jensen , Christopher Wittner , Elizabeth Benham , Anthony Eaton , Joel Martin , David Rohlfing
发明人： Youlu Yu , Max MacDaniel , Kathy Collins , Gil Hawley , Michael Jensen , Christopher Wittner , Elizabeth Benham , Anthony Eaton , Joel Martin , David Rohlfing
IPC分类号： C08F4/44 , B01J31/00
CPC分类号： C08F10/00 , C08F4/65912 , C08F4/65916 , C08F4/6592 , C08F4/65925 , C08F4/65927 , C08F210/16 , C08F2410/02 , C08F2420/02 , C08F2420/04 , Y10S526/943 , C08F4/025 , C08F4/65904 , C08F210/14 , C08F2500/17 , C08F2500/12 , C08F2500/05 , C08F4/6546
摘要： This invention provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer. This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, wherein said catalyst composition comprises contacting an organometal compound, an organoaluminum compound, and a treated solid oxide compound.

23. 发明申请

US20060094590A1 Organochromium/metallocene combination catalysts for producing bimodal resins 有权
标题翻译：用于生产双峰树脂的有机铬/茂金属组合催化剂
公开(公告)号：US20060094590A1
公开(公告)日：2006-05-04
申请号：US10980996
申请日：2004-11-04
申请人： Max McDaniel , Elizabeth Benham , Michael Jensen , Kathy Collins , Joel Martin , Gil Hawley
发明人： Max McDaniel , Elizabeth Benham , Michael Jensen , Kathy Collins , Joel Martin , Gil Hawley
IPC分类号： B01J31/00 , C08F4/44
CPC分类号： C08F10/00 , C08F4/65916 , C08F4/6592 , C08F4/65925 , C08F4/65927 , C08F110/02 , C08F2420/01 , C08F2420/02 , C08F4/63904 , C08F4/69 , C08F2500/01 , C08F2500/03
摘要： This invention relates to the field of olefin polymerization catalyst compositions, and methods for the polymerization and copolymerization of olefins, including polymerization methods using a supported catalyst composition. In one aspect, the present invention encompasses a catalyst composition comprising the contact product of at least one metallocene compound, at least one organochromium compound, at least one chemically-treated solid oxide, and at least one organoaluminum compound.
摘要翻译：本发明涉及烯烃聚合催化剂组合物领域，以及烯烃聚合和共聚方法，包括使用负载催化剂组合物的聚合方法。一方面，本发明包括催化剂组合物，其包含至少一种金属茂化合物，至少一种有机铬化合物，至少一种化学处理的固体氧化物和至少一种有机铝化合物的接触产物。

24. 发明申请

US20050137366A1 Organometal compound catalyst 审中-公开
公开(公告)号：US20050137366A1
公开(公告)日：2005-06-23
申请号：US10993958
申请日：2004-11-19
申请人： Max McDaniel , Kathy Collins , Gil Hawley , Michael Jensen , Elizabeth Benham , Anthony Eaton , Joel Martin , Christopher Wittner
发明人： Max McDaniel , Kathy Collins , Gil Hawley , Michael Jensen , Elizabeth Benham , Anthony Eaton , Joel Martin , Christopher Wittner
IPC分类号： B01J21/00 , B01J21/06 , B01J21/12 , B01J31/14 , B01J31/16 , B01J31/22 , B01J31/26 , B01J31/38 , C08F4/02 , C08F4/642 , C08F4/655 , C08F4/658 , C08F4/659 , C08F4/6592 , C08F10/02 , C08F110/02 , C08F4/44 , B01J31/00
CPC分类号： C08F10/02 , B01J31/143 , B01J31/1608 , B01J31/2295 , B01J31/26 , B01J31/38 , B01J2531/46 , B01J2531/48 , B01J2531/49 , C08F4/65904 , C08F4/65912 , C08F4/65925 , C08F110/02 , Y10S526/943 , C08F4/025 , C08F4/65916 , C08F2500/12
摘要： This invention provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer. This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, wherein said catalyst composition comprises a post-contacted organometal compound, a post-contacted organoaluminum compound, and a post-contacted treated solid oxide compound.

25. 发明申请

US20060094841A1 Organometal catalyst compositions 有权
标题翻译：有机金属催化剂组合物
公开(公告)号：US20060094841A1
公开(公告)日：2006-05-04
申请号：US11301461
申请日：2005-12-12
申请人： Max McDaniel , Elizabeth Benham , Michael Jensen , Joel Martin , Gil Hawley
发明人： Max McDaniel , Elizabeth Benham , Michael Jensen , Joel Martin , Gil Hawley
IPC分类号： C08F4/44 , B01J31/00
CPC分类号： B01J31/143 , B01J21/12 , B01J27/125 , B01J31/1608 , B01J31/1616 , B01J31/2295 , B01J31/38 , B01J2531/46 , B01J2531/48 , B01J2531/49 , C08F4/65912 , C08F4/6592 , C08F4/65925 , C08F4/65927 , C08F10/02 , C08F110/02 , Y10S526/943 , C08F4/65916 , C08F4/025
摘要： This invention provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer This invention also provides catalyst compositions that are useful for polymerizing at least one monomer to produce a polymer, wherein said catalyst composition comprises a post-contacted organometal compound, a post-contacted organoaluminum compound, and a post-contacted fluorided silica-alumina.
摘要翻译：本发明提供了可用于聚合至少一种单体以生产聚合物的催化剂组合物。本发明还提供可用于聚合至少一种单体以制备聚合物的催化剂组合物，其中所述催化剂组合物包含后接触的有机金属化合物，后接触的有机铝化合物和后接触的氟化二氧化硅 - 氧化铝。

26. 发明申请

US20050113245A1 STANNOXY-SUBSTITUTED METALLOCENE CATALYSTS FOR OLEFIN AND ACETYLENE POLYMERIZATION 有权
标题翻译：用于烯烃和乙烯聚合的硅烷取代的金属催化剂
公开(公告)号：US20050113245A1
公开(公告)日：2005-05-26
申请号：US10723350
申请日：2003-11-26
申请人： Joel Martin , Michael Jensen , Max McDaniel
发明人： Joel Martin , Michael Jensen , Max McDaniel
IPC分类号： C08F4/44 , C08F4/659 , C08F10/00 , C08F110/02 , C08F210/16
CPC分类号： C08F10/00 , C08F4/65912 , C08F4/65916 , C08F110/02 , C08F210/16 , C08F4/6592 , C08F2500/12 , C08F210/14
摘要： This invention relates to the field of olefin polymerization catalyst compositions, and methods for the polymerization and copolymerization of olefins, including polymerization methods using a catalyst composition. One aspect of this invention is the formation and use of a catalyst composition comprising a stannoxy-substituted half-sandwich metallocene and an activator for olefin polymerization processes. For example, this invention encompasses the preparation of (η5-C5H5)Ti(OSnPh3)Cl2, its contact with an activator, for example, zinc-impregnated chlorided alumina, to form a catalyst composition, and the use of this catalyst composition for polymerizing olefins or acetylenes.
摘要翻译：本发明涉及烯烃聚合催化剂组合物领域，以及烯烃聚合和共聚方法，包括使用催化剂组合物的聚合方法。本发明的一个方面是形成和使用包含苯氧基取代的半夹心金属茂和用于烯烃聚合方法的活化剂的催化剂组合物。例如，本发明包括制备（η5 -C 5 H 5 H 5）Ti（OSnPh 3 N））Cl 2，其与活化剂例如浸渍锌的氧化铝接触以形成催化剂组合物，以及使用该催化剂组合物来聚合烯烃或乙炔。

27. 发明授权

US08681317B2 Tracking method and measuring system having a laser tracker 有权
标题翻译：具有激光跟踪器的跟踪方法和测量系统
公开(公告)号：US08681317B2
公开(公告)日：2014-03-25
申请号：US13377209
申请日：2010-06-14
申请人： Daniel Moser , Joel Martin , Konrad Von Arb
发明人： Daniel Moser , Joel Martin , Konrad Von Arb
IPC分类号： G01C3/08
CPC分类号： G01S17/66 , G01S5/163 , G01S17/023
摘要： A target equipped with a reflector can be tracked in a measuring system including a laser tracker. The reflector is tracked by means of a tracking unit in a normal tracking mode and by means of a surveying device in an extraordinary tracking mode. A capturing unit having a detection range lying between the detection ranges of the tracking unit and of the surveying device is also present. If the target cannot be detected by the tracking unit but can be detected by the capturing unit, the orientation of the tracking unit is controlled according to a measurement by the capturing unit. If the target can then be detected by the tracking unit, a transition to the normal tracking mode is initiated. If the target can be detected only by the surveying device, the orientation of the tracking unit is controlled according to a measurement of the surveying device.
摘要翻译：配备有反射镜的目标可以在包括激光跟踪器的测量系统中跟踪。通过跟踪单元以正常跟踪模式并通过非常跟踪模式下的测量装置跟踪反射器。还存在具有位于跟踪单元和测量装置的检测范围之间的检测范围的捕获单元。如果跟踪单元不能检测到目标，但是可以由捕获单元检测到目标，则根据捕获单元的测量来控制跟踪单元的方向。如果跟踪单元可以检测到目标，则启动到正常跟踪模式的转换。如果仅由测量装置检测到目标，则根据测量装置的测量来控制跟踪单元的定向。

28. 发明申请

US20070237776A1 High affinity human antibodies to human IL-18 receptor 有权
标题翻译：人类IL-18受体高亲和力抗体
公开(公告)号：US20070237776A1
公开(公告)日：2007-10-11
申请号：US11784308
申请日：2007-04-06
申请人： Tammy Huang , Sean Stevens , Joel Martin , Jeanette Fairhurst , Kevin Pobursky , Margaret Karow , Joan Windsor , Warren Mikulka
发明人： Tammy Huang , Sean Stevens , Joel Martin , Jeanette Fairhurst , Kevin Pobursky , Margaret Karow , Joan Windsor , Warren Mikulka
IPC分类号： G01N33/53 , C07H21/04 , C12P21/06 , A61K39/395 , C12N5/06 , C07K16/28
CPC分类号： C07K16/2866 , C07K2317/21 , C07K2317/24 , C07K2317/56 , C07K2317/565 , C07K2317/76
摘要： An isolated antibody or antibody fragment that binds human interleukin-18 receptor alpha (hIL-18Rα), comprising a light chain variable region (LCVR) selected from the group consisting of SEQ ID NO: 5, 9, 13, 17, 21, 25, 29, 33, 37, 41, 45, 49, 53, 61, 65, 69, 73, 77, and 81 and/or a heavy chain variable region (HCVR) selected from the group consisting of SEQ ID NO: 3, 7, 11, 15, 19, 23, 27, 31, 35, 39, 43, 47, 51, 55, 59, 63, 67, 71, 75, and 79, or a fragment or sequence modified by an amino acid substitution, deletion or addition thereof.
摘要翻译：一种结合人白细胞介素-18受体α（hIL-18Rα）的分离的抗体或抗体片段，其包含选自SEQ ID NO：5,9,13,17,21,25的轻链可变区（LCVR），29,33,37,41,45,49,53,61,65,69,73,77和81和/或选自SEQ ID NO：3，SEQ ID NO：3的重链可变区（HCVR） 7,11,15,19,23,27,31,35,39,43,47,51,55,59,63,67,71,75和79，或由氨基酸取代修饰的片段或序列，删除或添加。

29. 发明授权

US06802406B2 Recoil brake isolation system 失效
公开(公告)号：US06802406B2
公开(公告)日：2004-10-12
申请号：US10321860
申请日：2002-12-17
申请人： Joel Martin
发明人： Joel Martin
IPC分类号： F16F942
CPC分类号： F41A25/02
摘要： A recoil brake isolation system for the hydraulic recoil brake cylinder of a large caliber gun, includes two sets of hydraulic valves disposed respectively within the inlet valve block and return valve block of the hydraulic cylinder, an orchestrated combination of which together block the flow of hydraulic fluid to or from the hydraulic cylinder during the recoil/counterrecoil cycle or upon failure of the hydraulic circuit. A method of hydraulically isolating a recoil brake cylinder of a large caliber gun for survivability and improved weapon performance and a gun incorporating such a system are also included.

30. 发明授权

US6011006A Method of treating hot flushes with hexapeptides 失效
标题翻译：用六肽处理热潮红的方法
公开(公告)号：US6011006A
公开(公告)日：2000-01-04
申请号：US261367
申请日：1999-03-03
申请人： Christian Thomsen , Joel Martin , Nils Langeland Johansen , Philip Just Larsen , Rolf Hohlweg
发明人： Christian Thomsen , Joel Martin , Nils Langeland Johansen , Philip Just Larsen , Rolf Hohlweg
IPC分类号： A61K38/08 , A61K38/10 , A61K38/00
CPC分类号： A61K38/10 , A61K38/08
摘要： The present invention relates to a method of treating migraine, non-insulin dependent diabetes mellitus (type II diabetes), sepsis, inflammation and/or vasomotor disturbances. This method utilizes a hexapeptide of formula (I)A.sup.1 -A.sup.2 -A.sup.3 -A.sup.4 -A.sup.5 -A.sup.6 -Y (I)wherein A.sup.1, A.sup.2, A.sup.3, A.sup.4, A.sup.5, A.sup.6 and Y are as defined in the specification.
摘要翻译：本发明涉及治疗偏头痛，非胰岛素依赖性糖尿病（II型糖尿病），败血症，炎症和/或血管舒缩障碍的方法。该方法利用式（I）A1-A2-A3-A4-A5-A6-Y（I）的六肽，其中A1，A2，A3，A4，A5，A6和Y如说明书中所定义。

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