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21. 发明授权

US07955377B2 Valve frame 有权
标题翻译：阀框
公开(公告)号：US07955377B2
公开(公告)日：2011-06-07
申请号：US12357646
申请日：2009-01-22
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61F2/06
CPC分类号： A61F2/2418 , A61F2/2475 , A61F2220/005 , A61F2220/0058 , A61F2220/0075
摘要： The disclosure relates to frames suitable for prosthetic implantable valves, and methods of treatment with such frames, to regulate blood flow and to be compliant in percutaneous delivery and, upon implantation, configured to conform to the changing shape of the body vessel or vein. The frames include at least one anchoring member attached to a support member at one or more attachments, and a valve member, preferably a monocuspid valve leaflet, attached to the support member. Preferred frames include two anchoring members with the support member in between the anchoring members. The support member preferably has a semielliptical shape and extends diagonally to sealingly contact the wall of the body vessel.
摘要翻译：本公开涉及适用于假体可植入瓣膜的框架，以及用这种框架进行治疗的方法，以调节血液流动并且在经皮输送中顺应，并且在植入时构造成符合身体血管或静脉的变化形状。框架包括在一个或多个附件处附接到支撑构件的至少一个锚固构件，以及连接到支撑构件的阀构件，优选地是单瓣瓣叶片。优选的框架包括两个锚固构件，其中支撑构件位于锚定构件之间。支撑构件优选地具有半椭圆形并且对角地延伸以密封地接触身体容器的壁。

22. 发明授权

US07811238B2 Wire guide having distal coupling tip 有权
标题翻译：导线器具有远端连接头
公开(公告)号：US07811238B2
公开(公告)日：2010-10-12
申请号：US11652430
申请日：2007-01-11
申请人： Jeffry S. Melsheimer , Christopher L. Hruska
发明人： Jeffry S. Melsheimer , Christopher L. Hruska
IPC分类号： A61M25/00
CPC分类号： A61M25/09 , A61M25/0905 , A61M2025/09175
摘要： A coupling wire guide structured to be slidably coupled to a previously introduced wire guide. The coupling wire guide includes a main body having a distal section. The distal section includes an outer wire disposed over a safety wire. A loop wire is connected to the safety wire at two axially spaced points. At least a portion of the loop wire is positioned outside of the outer wire to define a loop area sized to receive the previously introduced wire guide.
摘要翻译：耦合导线引导件，其被构造成可滑动地联接到先前引入的导线器。耦合导线器包括具有远端部分的主体。远侧部分包括设置在安全线上的外部线。环形线在两个轴向间隔的点处连接到安全线。环线的至少一部分定位在外线的外侧，以限定尺寸适于接收先前引入的线引导件的环形区域。

23. 发明授权

US07578838B2 Delivery system with helical shaft 有权
公开(公告)号：US07578838B2
公开(公告)日：2009-08-25
申请号：US11034913
申请日：2005-01-12
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61F2/84
CPC分类号： A61F2/91 , A61F2/915 , A61F2/95 , A61F2002/91525 , A61F2002/91533 , A61F2002/91575 , A61F2002/9665 , A61F2230/0054
摘要： A delivery system is provided for releasing a medical device within a body cavity. The delivery system may be used in an intravascular procedure to implant a self-expandable stent. A helical structure on the shaft of the delivery system engages the inner surface of the stent. As a result, the stent may be released by rotating the shaft relative to the stent which pushes the stent forward from the distal end of the shaft.

24. 发明申请

US20090171433A1 CONTROL HANDLE 有权
标题翻译：控制手柄
公开(公告)号：US20090171433A1
公开(公告)日：2009-07-02
申请号：US11965164
申请日：2007-12-27
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： A61F2/84
CPC分类号： A61F2/95 , A61F2002/9517 , A61M25/0133
摘要： A delivery device for deploying an expandable prosthesis and method of use thereof are described. The delivery device comprises a handle that comprises a trigger. Activation of the trigger enables incremental retraction of the outer sheath to expose a self-expanding prosthesis. Activation and subsequent deactivation of the trigger causes a movable member to ratchedly engage with a stationary rack and a trigger rack.
摘要翻译：描述了用于展开可扩张假体的输送装置及其使用方法。递送装置包括包括触发器的手柄。触发器的激活使外鞘的增量回缩能够暴露自膨胀假体。触发器的激活和随后的去激活使得可移动部件与固定架和触发架高效地接合。

25. 发明申请

US20090113693A1 APPARATUS AND METHOD FOR COMPRESSING A STENT 有权
标题翻译：装置和压缩方法
公开(公告)号：US20090113693A1
公开(公告)日：2009-05-07
申请号：US12261747
申请日：2008-10-30
申请人： Jeffry S. Melsheimer
发明人： Jeffry S. Melsheimer
IPC分类号： B23P11/00 , B23Q7/00
CPC分类号： A61F2/95 , A61F2002/9522 , Y10T29/49927 , Y10T29/53987 , Y10T29/53996
摘要： An apparatus for compressing a stent includes a flexible sheet having a first portion curved over toward a second portion of the sheet, such that the sheet includes a generally cylindrical opening. A compression wedge and a curved surface of a platen sandwich at least the second portion of the sheet, and the compression wedge is adjacent to the generally cylindrical opening. A size of the generally cylindrical opening is changed by relative curvilinear motion of the compression wedge and the platen.
摘要翻译：用于压缩支架的装置包括具有朝向片材的第二部分弯曲的第一部分的柔性片材，使得片材包括大致圆柱形的开口。压板和压板的曲面至少夹在片材的第二部分上，压缩楔与大致圆柱形的开口相邻。通常的圆柱形开口的尺寸通过压缩楔和压板的相对曲线运动而改变。

26. 发明申请

US20090093829A1 Chronic total occlusion (CTO) removal device 审中-公开
标题翻译：慢性完全闭塞（CTO）去除装置
公开(公告)号：US20090093829A1
公开(公告)日：2009-04-09
申请号：US11973452
申请日：2007-10-09
申请人： Jeffry S. Melsheimer , Jason Urbanski
发明人： Jeffry S. Melsheimer , Jason Urbanski
IPC分类号： A61B17/22
CPC分类号： A61B17/3207 , A61B17/32056 , A61B17/320708 , A61B17/320725 , A61B2017/22001 , A61B2017/22042 , A61B2017/22094 , A61B2017/2212 , A61B2017/320733 , A61B2017/320741
摘要： There is disclosed a device for removing chronic total occlusions (CTO) from blood vessels or other body lumens. In one embodiment the device has a loop at a distal end connected by a shaft to a proximal end. The shaft is provided inside a catheter that has an opening at the distal end and a handle at the proximal end. By manipulating the position of the loop relative to the opening, the effective stiffness of the loop may be changed. This allows a physician to vary the loop stiffness so as to be appropriate with regard to the toughness of a CTO (some CTOs have a relatively tough exterior but a relatively soft interior). The loop may have a single turn or may comprise two or more turns.
摘要翻译：公开了一种用于从血管或其他体腔去除慢性全部闭塞（CTO）的装置。在一个实施例中，该装置具有通过轴连接到近端的远端处的环。轴设置在导管内，该导管在远端具有开口，在近端具有手柄。通过操纵环相对于开口的位置，可以改变回路的有效刚度。这允许医师改变环路刚度，以便在CTO的韧性方面是适当的（一些CTO具有相对坚固的外部但是相对柔软的内部）。回路可以具有单圈或者可以包括两圈或更多圈。

27. 发明申请

US20090076435A1 Catheter Assembly 有权
标题翻译：导管大会
公开(公告)号：US20090076435A1
公开(公告)日：2009-03-19
申请号：US11857060
申请日：2007-09-18
申请人： Jeffry S. Melsheimer , Arman H. Valaie
发明人： Jeffry S. Melsheimer , Arman H. Valaie
IPC分类号： A61M37/00
CPC分类号： A61M25/0606 , A61M1/3653 , A61M1/3655 , A61M1/3659 , A61M25/0032 , A61M25/0631 , A61M2025/0031
摘要： A catheter assembly is provided with a flexible tubular body having two lumens. A solid slidable member with a sharp distal end is disposed within one of the lumens. The slidable member is capable of sliding within the lumen of the tubular body between an exposed position in which the sharp distal end of the slidable member protrudes from the distal end of the tubular body and a shielded position in which the distal end of the slidable member is within the tubular body. One advantage is that the sharp distal end of the slidable member may be withdrawn into the tubular body in order to shield a patient from unintentional cutting or irritation from the sharp distal end of the slidable member.
摘要翻译：导管组件设置有具有两个流明的柔性管状体。具有尖锐远端的固体可滑动构件设置在一个管腔内。可滑动构件能够在管状体的内腔内滑动在可滑动构件的尖锐远端从管状体的远端突出的暴露位置和可滑动构件的远端之间的屏蔽位置在管状体内。一个优点是，可滑动构件的尖锐远端可以被抽出到管状体中，以便屏蔽患者免受来自可滑动构件的尖锐远端的意外切割或刺激。

28. 发明申请

US20080228139A1 Angioplasty Balloon With Concealed Wires 审中-公开
标题翻译：血管成形术气球与隐形电线
公开(公告)号：US20080228139A1
公开(公告)日：2008-09-18
申请号：US12026461
申请日：2008-02-05
申请人： Jeffry S. Melsheimer , Kevin Leffel
发明人： Jeffry S. Melsheimer , Kevin Leffel
IPC分类号： A61M25/10
CPC分类号： A61M25/104 , A61M2025/1086
摘要： A balloon catheter having wires situated between an outer layer and a surface of a balloon is described. Each wire may be confined within an interior space of a pocket or encapsulated within a sheath. The pocket includes the outer layer and the balloon surface. The outer layer and balloon surface are unattached to allow the wire to slidably fit between therewithin. The pocket is selectively bonded to the balloon. The sheath includes a preformed shape that completely circumscribes the wire along the longitudinal and radial directions of the wire. The confined and encapsulated feature of the wires enable the wires to be atraumatic and remain spaced apart during treatment of calcification of a lesion.
摘要翻译：描述了具有位于球囊的外层和表面之间的线的球囊导管。每个线可以限制在口袋的内部空间内或者封装在护套内。口袋包括外层和气球表面。外层和气球表面未附着，以允许电线在其间滑动配合。口袋选择性地粘合到气囊上。护套包括沿导线的纵向和径向方向完全围绕导线的预成型形状。线的限制和封装特征使得电线在损伤的钙化治疗期间是无损伤的并保持间隔开的。

29. 发明申请

US20080071307A1 APPARATUS AND METHODS FOR IN SITU EMBOLIC PROTECTION 审中-公开
标题翻译：装置和方法用于疫苗保护
公开(公告)号：US20080071307A1
公开(公告)日：2008-03-20
申请号：US11857268
申请日：2007-09-18
申请人： Michael P. DeBruyne , Andrew K. Hoffa , Jeffry S. Melsheimer , Sarah E. Reeves
发明人： Michael P. DeBruyne , Andrew K. Hoffa , Jeffry S. Melsheimer , Sarah E. Reeves
IPC分类号： A61M29/00 , A61F2/06 , A61F2/84
CPC分类号： A61F2/013 , A61F2/07 , A61F2/95 , A61F2/958 , A61F2002/011 , A61F2002/075 , A61F2002/8486 , A61F2250/0048
摘要： The present invention provides apparatus and methods for treating a vascular condition by restoring patency to a vessel while reducing the likelihood that emboli become dislodged into the bloodstream. In a first embodiment, the apparatus comprises a graft having proximal and distal regions, a first support member attached to the distal region of the graft, and a second support member attached to the proximal region of the graft. The first and second support members may comprise first and second stents, respectively. The first stent is deployed distal to a vascular condition, and the second stent is deployed proximal to a vascular condition, such that the graft spans the length of the vascular condition to entrap emboli during treatment of the vascular condition. In an alternative embodiment, the first stent is adapted to be deployed within a vessel at a location distal to the vascular condition, and the graft is adapted to be everted to form a pocket adapted to entrap emboli dislodged during treatment of the vascular condition. The second stent then may be subsequently deployed proximal to the vascular condition, such that emboli trapped within the graft pocket are effectively sealed off from the bloodstream.
摘要翻译：本发明提供了通过恢复对血管的通畅来治疗血管病变的装置和方法，同时降低栓塞进入血流的可能性。在第一实施例中，该装置包括具有近端区域和远端区域的移植物，附接到移植物的远侧区域的第一支撑构件和附接到移植物的近端区域的第二支撑构件。第一和第二支撑构件可以分别包括第一和第二支架。第一个支架部署在血管状态的远端，第二个支架部署在血管状态附近，使得移植物横跨血管状态的长度以在治疗血管状况期间截留栓塞。在替代实施例中，第一支架适于在位于远离血管状态的位置处的血管内展开，并且移植物适于被转动以形成适于在治疗血管状况期间阻塞栓塞移出的口袋。然后可以将第二支架随后部署在血管状态附近，使得捕获在移植物袋内的栓塞被有效地从血流中密封。

30. 发明授权

US09913741B2 Control handle for self-expandable medical devices 有权
公开(公告)号：US09913741B2
公开(公告)日：2018-03-13
申请号：US13542137
申请日：2012-07-05
申请人： Jeffry S. Melsheimer , Grant T. Hoffman , Joseph E. Hughes , Gregory A. Frankland , Tyler Bunch
发明人： Jeffry S. Melsheimer , Grant T. Hoffman , Joseph E. Hughes , Gregory A. Frankland , Tyler Bunch
IPC分类号： A61F2/06 , A61F2/95 , A61F2/966
CPC分类号： A61F2/95 , A61F2/966 , A61F2002/9517
摘要： A delivery system is provided for a self-expanding medical device. The delivery system has a handle assembly with a housing. The housing has a slot with a deployment knob extending therethrough. The self-expanding medical device is deployed by restraining the housing of the handle assembly and pulling on the deployment knob. This causes an outer sheath to withdraw proximally from an inner catheter to release the self-expanding medical device from a space between the outer sheath and inner catheter.

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