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    • 22. 发明授权
    • 7-deazapurine derivatives useful as antitumor agents
    • 可用作抗肿瘤剂的7-脱氮嘌呤衍生物
    • US4650868A
    • 1987-03-17
    • US729202
    • 1985-05-01
    • Susumu NishimuraHiroaki NomuraHiroshi Akimoto
    • Susumu NishimuraHiroaki NomuraHiroshi Akimoto
    • A61K31/505A61P35/00C07D487/04C07F7/10C07F7/18C07D471/02
    • C07D487/04Y02P20/55
    • 7-Deazapurine derivatives of the formula: ##STR1## wherein R.sup.1 is phenyl which has, at the ortho position and/or para position as substituents, at least one group represented by the formula --O--R.sup.3, --S--R.sup.4 or ##STR2## (wherein R.sup.3, R.sup.4, R.sup.5 and R.sup.6 are the same or different and each is hydrogen or an alkyl or phenyl group which may be substituted, whereby R.sup.5 and R.sup.6, together with the adjacent nitrogen atom, may form a cyclic amino group which may be substituted, and R.sup.3, R.sup.4, R.sup.5 and R.sup.6 each may represent a protective group), and may have a group or groups with a molecular weight of up to about 200 as a substituent at any position other than those having the said substituents introduced; R.sup.2 is an amino group which may be protected, or its salt, have a potent antitumor activity, and hence the compounds are useful as an antitumor agent.
    • 其中R 1是在取代基的邻位和/或对位具有至少一个由式-O-R 3,-S-R 4或(其中R 3,R 4,R 5和R 6相同或不同,各自为氢或可被取代的烷基或苯基,其中R 5和R 6与相邻的氮原子一起可形成环状氨基, 并且R 3,R 4,R 5和R 6各自可以表示保护基),并且可以具有除了引入了所述取代基的那些以外的任何位置具有至多约200的分子量的基团作为取代基的基团; R2是可被保护的氨基或其盐具有有效的抗肿瘤活性,因此该化合物可用作抗肿瘤剂。
    • 27. 发明授权
    • Connector
    • 连接器
    • US08727810B2
    • 2014-05-20
    • US13534434
    • 2012-06-27
    • Takushi YoshidaHiroshi Akimoto
    • Takushi YoshidaHiroshi Akimoto
    • H01R24/00
    • H01R4/028H01R13/2442
    • A connector which is capable of preventing spring characteristics of contacts from changing due to sucking up of solder. A plurality of contacts each include a contact portion in contact with an electrode of a card-type electronic component, a spring portion for pressing the contact portion against the electrode of the card-type electronic component, and a connection portion which is soldered to a pad on a printed substrate. The spring portion of each contact is formed with a low wettability area on an end thereof toward the connection portion, to which solder is less likely to adhere.
    • 能够防止由于吸料引起的触点弹簧特性变化的连接器。 多个触点各自包括与卡式电子部件的电极接触的接触部分,用于将接触部分压靠在卡型电子部件的电极上的弹簧部分和焊接到卡型电子部件的连接部分 垫在印刷基板上。 每个接触件的弹簧部分在其一端上朝向连接部分形成低润湿性区域,焊料不太可能粘附到该连接部分上。
    • 29. 发明授权
    • Contact member and connector
    • 接触件和接头
    • US07811094B2
    • 2010-10-12
    • US12256625
    • 2008-10-23
    • Takashi KuwaharaSeiya TakahashiHiroshi Akimoto
    • Takashi KuwaharaSeiya TakahashiHiroshi Akimoto
    • H01R12/00
    • H01R13/2407H01R12/592
    • A contact member which is resistant to contact failure even if the environment of use is bad. A film is affixed to the surface of a long plate-shaped elastic body which is disposed between two to-be-connected objects. A electrically-conducting path which electrically connects between terminal portions of two to-be-connected objects is provided on the surface of the film. A first conductor contact portion which is capable of being brought into contact with the terminal portion of one of two to-be-connected objects is disposed at one end of the electrically-conducting path, and a second conductor contact portion which is capable of being brought into contact with the terminal portion of the other of two to-be-connected objects is disposed at the other end of the electrically-conducting path. A plurality of holes are formed in the first and second conductor contact portions.
    • 即使使用环境不良,也能够抵抗接触不良的接触部件。 薄膜固定在长板状弹性体的表面上,该长板状弹性体设置在两个被连接物体之间。 在膜的表面上设置导电路径,其电连接两个被连接物体的端子部分。 能够与两个待连接物体之一的端子部分接触的第一导体接触部分设置在导电路径的一端,以及第二导体接触部分,其能够被 与两个被连接物体中的另一个的端子部分接触设置在导电路径的另一端。 多个孔形成在第一和第二导体接触部分中。