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22. 发明授权

EP3027625B1 SPIRO-FUSED DERIVATIVES OF PIPERIDINE USEFUL FOR THE TREATMENT OF INTER ALIA HYPERTENSION AND ACUTE OR CHRONIC HEART FAILURE 有权转让
公开(公告)号：EP3027625B1
公开(公告)日：2018-05-30
申请号：EP14831878.5
申请日：2014-07-28
申请人： Merck Sharp & Dohme Corp.
发明人： TANG, Haifeng , PIO, Barbara , JIANG, Jinlong , PASTERNAK, Alexander , DONG, Shuzhi , FERGUSON, Ronald Dale, II , GUO, Zack Zhiqiang , CHOBANIAN, Harry , FRIE, Jessica , GUO, Yan , WU, Zhicai , YU, Yang , WANG, Ming
IPC分类号： C07D498/12
CPC分类号： C07D471/10 , A61K31/435 , A61K31/444 , A61K31/46 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5386 , A61K45/06 , C07D451/00 , C07D493/04 , C07D498/10
摘要： The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

23. 发明公开

EP3212616A1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL 审中-公开
公开(公告)号：EP3212616A1
公开(公告)日：2017-09-06
申请号：EP15854604.4
申请日：2015-10-26
申请人： Merck Sharp & Dohme Corp.
发明人： PASTERNAK, Alexander , DONG, Shuzhi , GU, Xin , JIANG, Jinlong , SHI, Zhi-Cai , WALSH, Shawn P. , WU, Zhicai , YU, Yang , FERGUSON, Ronald II , GUO, Zhiqiang , FRIE, Jessica , SUZUKI, Takao , BLIZZARD, Timothy A. , FU, Qinghong , VANGELDER, Kelsey F.
IPC分类号： C07D211/28 , C07D211/62
CPC分类号： C07D498/10 , A61K31/401 , A61K31/41 , A61K31/4178 , A61K31/4184 , A61K31/435 , A61K31/4422 , A61K31/444 , A61K31/4965 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/519 , A61K31/5386 , A61K31/55 , A61K31/551 , A61K31/585 , A61K31/675 , A61P3/14 , A61P7/10 , A61P9/12 , C07D471/10 , C07D497/10 , A61K2300/00
摘要： The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

24. 发明授权

EP2877471B1 SPIRO-FUSED PIPERIDINE DERIVATIVES FOR USE AS INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL 有权转让
标题翻译：螺旋稠哌啶，肾外髓钾通道抑制剂
公开(公告)号：EP2877471B1
公开(公告)日：2016-11-02
申请号：EP13745315.5
申请日：2013-07-25
申请人： Merck Sharp & Dohme Corp.
发明人： DING,Fa-Xiang , DONG, Shuzhi , FRIE, Jessica , GU,Xin , JIANG, Jinlong , PASTERNAK, Alexander , TANG, Haifeng , WU, Zhieai , YU, Yang , SUZUKI, Takao
IPC分类号： C07D471/10 , C07D471/20 , C07D519/00 , A61K31/438 , A61P9/12
CPC分类号： C07D498/20 , A61K31/435 , A61K31/46 , A61K31/4995 , A61K31/5386 , A61K45/06 , C07D451/00 , C07D471/10 , C07D471/20 , C07D519/00

26. 发明公开

EP3027625A1 INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL 有权转让
公开(公告)号：EP3027625A1
公开(公告)日：2016-06-08
申请号：EP14831878.5
申请日：2014-07-28
申请人： Merck Sharp & Dohme Corp.
发明人： TANG, Haifeng , PIO, Barbara , JIANG, Jinlong , PASTERNAK, Alexander , DONG, Shuzhi , FERGUSON, Ronald Dale, II , GUO, Zack Zhiqiang , CHOBANIAN, Harry , FRIE, Jessica , GUO, Yan , WU, Zhicai , YU, Yang , WANG, Ming
IPC分类号： C07D498/12
CPC分类号： C07D471/10 , A61K31/435 , A61K31/444 , A61K31/46 , A61K31/497 , A61K31/501 , A61K31/506 , A61K31/5386 , A61K45/06 , C07D451/00 , C07D493/04 , C07D498/10
摘要： The present invention provides compounds of Formula I and the pharmaceutically acceptable salts thereof, which are inhibitors of the ROMK (Kir1.1) channel. The compounds may be used as diuretic and/or natriuretic agents and for the therapy and prophylaxis of medical conditions including cardiovascular diseases such as hypertension, heart failure and chronic kidney disease and conditions associated with excessive salt and water retention.

27. 发明申请

WO2022095010A1 METHODS AND APPARATUS FOR RASTERIZATION OF COMPUTE WORKLOADS 审中-公开
公开(公告)号：WO2022095010A1
公开(公告)日：2022-05-12
申请号：PCT/CN2020/127436
申请日：2020-11-09
申请人： QUALCOMM INCORPORATED , ZHANG, Yibin , YING, Zilin , DU, Yun , QI, Heng , YU, Jiexia , YU, Yang , GRUBER, Andrew, Evan , LIANG, Jian , WANG, Tao , BOURD, Alexei Vladimirovich , ZHONG, Gang , HUANG, Minjie
发明人： ZHANG, Yibin , YING, Zilin , DU, Yun , QI, Heng , YU, Jiexia , YU, Yang , GRUBER, Andrew, Evan , LIANG, Jian , WANG, Tao , BOURD, Alexei Vladimirovich , ZHONG, Gang , HUANG, Minjie
IPC分类号： G06T1/00
摘要： The present disclosure relates to methods and apparatus for graphics processing, e.g., a GPU. The apparatus may receive an image including a plurality of pixels associated with one or more workgroups and one or more pixel tiles, each of the workgroups and the pixel tiles including one or more pixels of the plurality of pixels. The apparatus may determine whether the one or more workgroups are misaligned with the one or more pixel tiles. The apparatus may determine a conversion order of the one or more workgroups when the one or more workgroups are misaligned with the one or more pixel tiles, the conversion order corresponding to a common multiple of one of the one or more workgroups and one of the one or more pixel tiles. The apparatus may convert each of the one or more workgroups based on the conversion order of the one or more workgroups.

28. 发明申请

WO2016188573A1 METHODS AND NODES IN A WIRELESS COMMUNICATION NETWORK 审中-公开
标题翻译：无线通信网络中的方法和方法
公开(公告)号：WO2016188573A1
公开(公告)日：2016-12-01
申请号：PCT/EP2015/061770
申请日：2015-05-28
申请人： HUAWEI TECHNOLOGIES CO., LTD. , YU, Yang , CALABRESE, Francesco Davide
发明人： YU, Yang , CALABRESE, Francesco Davide
IPC分类号： H04W52/54 , H04W52/14 , H04W52/40
CPC分类号： H04W52/545 , H04W52/146 , H04W52/40
摘要： A Controlling Network Node (130) and a method (500) therein, in a communication network (100), for providing a power control command for a RL (140-1, 140-2, …, 140-n) associated with a UE (120). The CNN (130) comprises a processing unit (820), configured to dedicate one set of power control bits (510-9) comprised in a DL dedicated physical channel slot (300), for RLs (140-1, 140-2, …, 140-n) communicating with any non-serving cell (320); set the dedicated set of power control bits (510-9) to an incrementing command; detect a RL (140- 1, 140-2, …, 140-n) for communication with any non-serving cell (320); assign the dedicated set of power control bits (510-9) to the detected RL (140-1, 140-2, …, 140-n); and provide the DL dedicated physical channel slot (300) to the UE (120).
摘要翻译：一种在通信网络（100）中的控制网络节点（130）和方法（500），用于为与（a）相关联的RL（140-1,140-2，...，140-n）提供功率控制命令 UE（120）。 CNN（130）包括处理单元（820），被配置为专用于包含在DL专用物理信道时隙（300）中的一组功率控制位（510-9），用于RL（140-1,140-2， ...，140-n）与任何非服务小区（320）通信; 将专用功率控制位组（510-9）设置为递增命令; 检测用于与任何非服务小区（320）通信的RL（140-1,140-2，...，140-n）; 将专用的功率控制位集合（510-9）分配给检测到的RL（140-1,140-2，...，140-n）; 并将DL专用物理信道时隙（300）提供给UE（120）。

29. 发明申请

WO2011147257A1 METHOD FOR GROUP-BASED MULTICAST WITH NON-UNIFORM RECEIVERS 审中-公开
标题翻译：基于非均匀接收器的基于群的多播方法
公开(公告)号：WO2011147257A1
公开(公告)日：2011-12-01
申请号：PCT/CN2011/073907
申请日：2011-05-11
申请人： HUAWEI TECHNOLOGIES CO., LTD. , DAI, Weiqian , LI, Ming , LI, Renwei , DONG, Xuesong , YU, Yang , STEWART, Randall
发明人： DAI, Weiqian , LI, Ming , LI, Renwei , DONG, Xuesong , YU, Yang , STEWART, Randall
IPC分类号： H04L12/56
CPC分类号： H04L12/184 , H04L12/185 , H04L12/1868 , H04L12/1877 , H04L12/1881
摘要： An apparatus comprising a proxy configured to couple to a sender and a receiver and to receive data from the sender at a first rate and forward the data to the receiver at a second rate that is less than the first rate. A method comprising detecting a reception speed for each of a plurality of receivers in a multicast group, assigning the receivers to a first group and a second group based on the reception speed of each of the receivers, wherein the first group has a reception speed that is faster than a reception speed of the second group, and sending multicast data intended for all of the receivers to the receivers in the first group and to a proxy at a first rate, wherein the proxy buffers the multicast data and sends the multicast data to the receivers in the second group at a second rate.
摘要翻译：一种包括被配置为耦合到发送器和接收器并且以第一速率从发送器接收数据的代理的设备，并且以小于第一速率的第二速率将数据转发到接收器。一种方法，包括检测多播组中的多个接收机中的每一个的接收速度，基于每个接收机的接收速度将接收机分配给第一组和第二组，其中第一组的接收速度为比第二组的接收速度快，并且将针对所有接收机的组播数据发送到第一组中的接收机，并以第一速率发送给代理，其中代理缓存多播数据并将多播数据发送到第二组中的接收机以第二速率。

30. 发明申请

WO2011059856A2 DYNAMIC REFERENCE FRAME REORDERING FOR FRAME SEQUENTIAL STEREOSCOPIC VIDEO ENCODING 审中-公开
标题翻译：帧顺序立体视频编码的动态参考帧重排
公开(公告)号：WO2011059856A2
公开(公告)日：2011-05-19
申请号：PCT/US2010/055120
申请日：2010-11-02
申请人： SONY CORPORATION , HONG, Seungwook , YU, Yang
发明人： HONG, Seungwook , YU, Yang
CPC分类号： H04N19/114 , H04N19/149 , H04N19/172 , H04N19/46 , H04N19/597 , H04N19/61
摘要： Encoding of video sequences for frame sequential stereoscopic video, such as from spatially distinct right and left imagers. During the encoding process, reference frames are reordered if it is determined that reordering will increase the number of macroblocks (MBs) which can be skipped from the encoded output, or to otherwise increase coding efficiency. Then encoding is completed using motion prediction and entropy encoding for frame sequential stereoscopic video in response to the ordering of the reference frames. Side-information is encoded about reference frame sequencing within the sequential stereoscopic video output allowing a decoder to properly decode the reference frames. As a result the number of skipped MBs can be dramatically increased and the number of MBs referenced during motion prediction significantly reduced.
摘要翻译：用于帧顺序立体视频的视频序列的编码，例如从空间上不同的右和左成像器编码。在编码过程中，如果确定重新排序会增加可从编码输出中跳过的宏块（MB）的数量，或者以其他方式提高编码效率，则参考帧被重新排序。然后，响应于参考帧的排序，使用针对帧顺序立体视频的运动预测和熵编码来完成编码。在连续立体视频输出内关于参考帧排序的侧面信息被编码，允许解码器正确解码参考帧。结果，跳过的MB的数量可以显着增加，并且在运动预测期间引用的MB的数量显着减少。

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