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21. 发明专利

JP2009297532A Electronic lead for medical implant device, method of making the same, and method and apparatus for inserting the same 审中-公开
标题翻译：用于医用植入装置的电子引线，其制造方法以及插入其的方法和装置
公开(公告)号：JP2009297532A
公开(公告)日：2009-12-24
申请号：JP2009197590
申请日：2009-08-28
申请人： Medtronic Minimed Inc , メドトロニックミニメドインコーポレイテッド
发明人： GIBSON SCOTT R , SHAH RAJIV , CHERNOFF EDWARD , BYERS CHARLES
IPC分类号： A61N1/02 , A61N1/05 , A61N1/36
CPC分类号： A61N1/3752 , A61N1/05 , Y10S439/909
摘要： PROBLEM TO BE SOLVED: To improve reliability of an implant relating to electronic leads for implants and tools for using such electronic leads. SOLUTION: An implantable coaxial lead includes a cable with male and female connectors. The cable includes inner and outer helical coils separated by an inner insulating tube and is accompanied with an outer insulating tube surrounding the outer helical coil. The male connector includes an outer conductive cylinder, a conductive pin and an insulator molded in between. In order to increase strength, a braided cylinder, infiltrated with rubber, is arranged at the juncture of the male connector and the cable. The female connector includes a cylinder formed by two conducting body elements (400, 402) and an intervening insulating body element (401). The female connector includes respective conductive tension elements (408, 416) configured to combine the male connector. A first seal (412) is provided between the conductive tension members, used for electrical isolation and tactile feedback. An insertion tool includes a cylinder with a hollow bore and a detachable head, and a rod for pulling the lead in the cylinder. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译：要解决的问题：提高与用于使用这种电子引线的植入物和工具的电子引线相关的植入物的可靠性。
解决方案：可植入同轴引线包括带有阳和阴连接器的电缆。电缆包括由内绝缘管分隔的内螺旋线圈和外螺旋线圈，并且伴随着围绕外螺旋线圈的外绝缘管。阳连接器包括外导电圆筒，导电针和模制在其间的绝缘体。为了提高强度，在阳连接器和电缆的接合处布置有浸入橡胶的编织圆筒。阴连接器包括由两个导电体元件（400,402）和中间绝缘体元件（401）形成的圆筒。阴连接器包括被配置为组合阳连接器的各自的导电张力元件（408,416）。在用于电绝缘和触觉反馈的导电张力构件之间设置第一密封件（412）。插入工具包括具有中空孔的圆柱体和可拆卸的头部，以及用于将引线牵引在圆筒中的杆。版权所有（C）2010，JPO＆INPIT

22. 发明专利

CA2648151C METHODS AND MATERIALS FOR CONTROLLING THE ELECTROCHEMISTRY OF ANALYTE SENSORS 未知
公开(公告)号：CA2648151C
公开(公告)日：2022-08-23
申请号：CA2648151
申请日：2007-04-04
申请人： MEDTRONIC MINIMED INC
发明人： SHAH RAJIV , HOSS UDO , GOTTLIEB REBECCA K , SOUNDARARAJAN GOPIKRISHNAN , HOLKER JAMES D
IPC分类号： G01N33/487 , A61B5/00 , G01N27/30 , G01N27/327
摘要： Methods and sensors for detecting an analyte in a fluid, wherein the sensors comprises at least one electorde disposed upon a base substrate, the base substrate includes a geometric feature selected to increase the surface area of an electrochemically reactive surface on the electrode disposed thereon.

23. 发明专利

CA2789814C ANALYTE SENSOR APPARATUSES HAVING IMPROVED ELECTRODE CONFIGURATIONS AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：CA2789814C
公开(公告)日：2019-06-25
申请号：CA2789814
申请日：2011-03-15
申请人： MEDTRONIC MINIMED INC
发明人： WOLFE KATHERINE T , KANTAK AMEYA S , LARSON ERIC ALLAN , PESANTEZ DANIEL E , XI DONGJUAN , CHIU CHIA-HUNG , SHAH RAJIV
IPC分类号： G01N27/403 , A61B5/1486 , G01N27/49
摘要： Embodiments of the invention provide analyte sensors having optimized elements and/or configurations of elements as well as methods for making and using such sensors. Typical embodiments of the invention include glucose sensors used in the management of diabetes, comprising : a plurality of sensor wires (301, 302, 303, 304) having a first end and second end and each arranged in a substanially common orientation, the plurality of sensor wires being electically conductive and including: a first sensor wire (303, 304) substantially covered by a first electically insulating cover (310), wherein a aperture in the first electrically insulating cover defines a working electrode area (313, 314); a second sensor wire (301) substantially covered by a second electrically insulating cover (310), wherein an aperture in the second electrically insulating cover defines a reference electrode area (311); and a third sensor wire (302) substantially covered by a third electrically insulating insulating cover (310), wherein an aperture in the third electrically insulating cover defines a counter electrode area (312).

24. 发明专利

CA2774778C ANALYTE SENSOR APPARATUSES HAVING INTERFERENCE REJECTION MEMBRANES AND METHODS FOR MAKING AND USING THEM 未知
公开(公告)号：CA2774778C
公开(公告)日：2018-06-19
申请号：CA2774778
申请日：2010-10-01
申请人： MEDTRONIC MINIMED INC
发明人： YANG QINGLING , SHAH RAJIV , LITTLE MEGAN E , CHIU CHIA-HUNG
IPC分类号： G01N27/49 , C08L33/08 , C12Q1/00 , G01N33/487
摘要： Embodiments of the invention provide amperometric analyte sensors having optimized elements such as interference rejection membranes as well as methods for making and using such sensors. While embodiments of the innovation can be used in a variety of contexts, typical embodiments of the invention include glucose sensors used in the management of diabetes.

25. 发明专利

CA3088255A1 METHODS FOR CONTINUOUS GLUCOSE MONITORING 未知
公开(公告)号：CA3088255A1
公开(公告)日：2017-07-06
申请号：CA3088255
申请日：2016-07-22
申请人： MEDTRONIC MINIMED INC
发明人： NOGUEIRA KEITH , ENGEL TALY G , LI XIAOLONG , LIANG BRADLEY C , SHAH RAJIV , LIU MIKE C , TSAI ANDY Y , KIM JAEHO , VARSAVSKY ANDREA , YU FEI , GAUTHAM RAGHAVENDHAR , NISHIDA JEFFREY
摘要： Electrochemical impedance spectroscopy (EIS) may be used in conjunction with continuous glucose monitoring (CGM) to enable identification of valid and reliable sensor data, as well implementation of Smart Calibration algorithms. Calibration of a glucose sensor may also be performed using a calibration factor based on the age of the sensor. Finally, a calibration interval for a glucose sensor may be determined.

26. 发明专利

DK2214737T3 Antimikrobielle belægninger til medicinsk udstyr og fremgangsmåder til fremstilling og anvendelse deraf 未知
公开(公告)号：DK2214737T3
公开(公告)日：2015-04-20
申请号：DK08849279
申请日：2008-11-13
申请人： MEDTRONIC MINIMED INC
发明人： YANG ZHONGPING , JIN EUNJOO , CHRISTOFERSON LAURA , SHAH RAJIV
IPC分类号： A61L27/54 , A61L27/34

27. 发明专利

AU2013272046A1 Application of electrochemical impedance spectroscopy in sensor systems, devices, and related methods 未知
公开(公告)号：AU2013272046A1
公开(公告)日：2014-12-04
申请号：AU2013272046
申请日：2013-05-24
申请人： MEDTRONIC MINIMED INC
发明人： YANG NING , GAUTHAM RAGHAVENDHAR , LIANG BRADLEY C , SHAH RAJIV , SZYMAN CATHERINE M , MILLER MICHAEL E , WANG JENN-HANN LARRY , LI YIWEN , MORGAN WAYNE A , CHEN PARIS , MUCIC ROBERT C , DE BARROS GENIVAL D , CALLIRGOS CARLOS A , SIRIGIRI MANJUNATH , BRINSON JOSEPH PAUL
IPC分类号： A61B5/00 , A61B5/145 , A61B5/1486 , A61B5/1495
摘要： A diagnostic Electrochemical Impedance Spectroscopy (EIS) procedure is applied to measure values of impedance-related parameters for one or more sensing electrodes. The parameters may include real impedance, imaginary impedance, impedance magnitude, and/or phase angle. The measured values of the impedance-related parameters are then used in performing sensor diagnostics, calculating a highly-reliable fused sensor glucose value based on signals from a plurality of redundant sensing electrodes, calibrating sensors, detecting interferents within close proximity of one or more sensing electrodes, and testing surface area characteristics of electroplated electrodes. Advantageously, impedance-related parameters can be defined that are substantially glucose-independent over specific ranges of frequencies. An Application Specific Integrated Circuit (ASIC) enables implementation of the ElS-based diagnostics, fusion algorithms, and other processes based on measurement of ElS-based parameters.

28. 发明专利

CA2764284C A SYSTEM AND METHOD FOR PROVIDING CLOSED LOOP INFUSION FORMULATION DELIVERY 未知
公开(公告)号：CA2764284C
公开(公告)日：2014-04-15
申请号：CA2764284
申请日：2002-09-04
申请人： MEDTRONIC MINIMED INC
发明人： STARKWEATHER TIMOTHY J , LEBEL RONALD J , SHAH RAJIV , MILLER MICHAEL E
IPC分类号： A61M5/168 , A61K38/28 , A61M5/142 , A61M5/172 , G01N33/66 , G06F19/00
摘要： A system and method for providing closed loop infusion formulation delivery which accurately calculates a delivery amount based on a sensed biological state by adjusting an algorithm's programmable control parameters. The algorithm calculates a delivery amount having proportional, derivative, and basal rate components. The control parameters may be adjusted in real time to compensate for changes in a sensed biological state that may result from daily events. Safety limits on the delivery amount may be included in the algorithm. The algorithm may be executed by a computing element within a process controller for controlling closed loop infusion forumulation delivery. The biological state is sensed by a sensing device which provides a signal to the controller. The controller calculates an infusion formulation delivery amount based on the signal and sends commands to an infusion formulation delivery device which delivers an amount of infusion formulation determined by the commands.

29. 发明专利

DK2229095T3 System og fremgangsmåde til bestemmelse af hydreringspunktet og et passende tidspunkt til at påføre en glucosesensor et potentiale 未知
公开(公告)号：DK2229095T3
公开(公告)日：2013-01-02
申请号：DK08868118
申请日：2008-12-16
申请人： MEDTRONIC MINIMED INC
发明人： COOPER KENNETH W , CHOY DAVID Y , SHAH RAJIV , SOUNDARARAJAN GOPIKRISHNAN , VEJELLA RATNAKAR
IPC分类号： A61B5/00 , A61B5/15 , G01N27/00 , G01R31/02

30. 发明专利

CA2754724C METHODS OF FILLING VIAS IN A SUBSTRATE 未知
公开(公告)号：CA2754724C
公开(公告)日：2012-12-18
申请号：CA2754724
申请日：2003-09-15
申请人： MEDTRONIC MINIMED INC
发明人： SHAH RAJIV , PENDO SHAUN , BABIRACKI EDWARD G
IPC分类号： H01L21/71 , H01L21/48 , H05K1/16 , H05K3/04 , H05K3/40 , H05K3/46
摘要： A multilayer substrate device formed from a base substrate and alternating metalization layers and dielectric layers. Each layer is formed without firing. Vias may extend through one of the dielectric layers such that two metalization layers surrounding the dielectric layers make contact with each other. The vias may be formed by placing pillars on top of a metalization layer, forming a dielectric layer on top of the metalization layer and surrounding the pillars, and removing the pillars. Dielectric layers may be followed by other dielectric layers and metalization layers may be followed by other metalization layers.

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