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21. 发明申请

US20080139935A1 Apparatus, System, and Method for Adaptively Controlling A Frame Interval Between Ultrasound Scanning Frames For An Ultrasound Elasticity Imaging Scan 有权
标题翻译：用于适应性地控制超声波扫描框架之间的帧间隔的装置，系统和方法用于超声弹性成像扫描
公开(公告)号：US20080139935A1
公开(公告)日：2008-06-12
申请号：US11567285
申请日：2006-12-06
申请人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
发明人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
IPC分类号： A61B8/14 , G05B11/06
CPC分类号： A61B8/485 , A61B8/08 , A61B8/0858 , G01N29/041 , G01N29/043 , G01S7/52085
摘要： An apparatus, system and method for adaptively controlling a frame interval between ultrasound scanning frames of an ultrasound elasticity imaging scan. The system includes a transmitter for transmitting ultrasound beams to a subject during an ultrasound elasticity imaging scan, and a receiver for receiving ultrasound beam echoes from the subject responsive to transmitted ultrasound beams. The system also includes a processor for processing a plurality of the ultrasound beam echoes to determine a strain variation of the tissue undergoing strain, calculating a value for an ultrasound scanning frame interval adapted for imaging the tissue undergoing the determined strain variation, and setting the value of the ultrasound scanning frame interval for acquiring ultrasound elasticity images of the tissue undergoing the determined strain variation.
摘要翻译：一种用于自适应地控制超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法。该系统包括用于在超声波弹性成像扫描期间将超声波束发送到被摄体的发射器，以及用于响应于所发送的超声波束从受检者接收超声波束回波的接收器。该系统还包括处理器，用于处理多个超声波束回波以确定经历应变的组织的应变变化，计算适于对经历所确定的应变变化的组织进行成像的超声扫描帧间隔的值，以及设定值的超声扫描帧间隔，用于获取经历所确定的应变变化的组织的超声弹性图像。

22. 发明申请

US20070100240A1 FLYWHEEL VIBRATOR 有权
标题翻译：飞行员振动
公开(公告)号：US20070100240A1
公开(公告)日：2007-05-03
申请号：US11163912
申请日：2005-11-03
申请人： Karsten Hiltawsky
发明人： Karsten Hiltawsky
IPC分类号： A61B8/14
CPC分类号： A61B8/14 , A61B5/0051 , A61B5/6843 , A61B8/4483 , A61B8/485
摘要： The present invention is directed to an imaging tool to introduce a vibrational force into an object. The imaging tool includes a pair of flywheels that are driven by a motor in opposing rotational paths so as to introduce a harmonic mechanical excitation to the object. The imaging tool is constructed to be of handheld size so as to be suitable for ultrasound and is RF-compatible with MR scanners.
摘要翻译：本发明涉及一种将振动力引入物体的成像工具。成像工具包括一对飞轮，其由相对旋转路径中的电动机驱动，以便向对象引入谐波机械激励。成像工具被构造为具有手持尺寸以便适合于超声波，并与MR扫描仪RF兼容。

23. 发明申请

US20130063141A1 APPARATUS AND METHOD FOR IDENTIFYING MAGNETICALLY MARKED MICRO OBJECTS 审中-公开
标题翻译：用于识别磁性标记的微物体的装置和方法
公开(公告)号：US20130063141A1
公开(公告)日：2013-03-14
申请号：US13698526
申请日：2011-05-13
申请人： Karsten Hiltawsky , Roland Weiss
发明人： Karsten Hiltawsky , Roland Weiss
IPC分类号： G01R33/02
CPC分类号： G01N33/54326 , G01N15/1468 , G01N35/00069 , G01N35/0098
摘要： An apparatus is disclosed for identifying magnetically marked micro objects, in particular biological micro objects, preferably tumor cells. In at least one embodiment, the apparatus includes a carrier for at least one micro object; a device for applying a region with a magnetic gradient field, wherein the gradient field comprises at least one zero point; a device for applying the micro object with a high frequency magnetic field, in particular at the site of the zero point; a device for relative movement of the carrier and region to one another; a device for receiving a change in a magnetic flux through the micro object; a device for evaluating the received change in the magnetic flux and for identifying the position of the micro object; and a device for in particular automatically analyzing the micro object.
摘要翻译：公开了用于识别磁性标记的微物体，特别是生物微物体，优选肿瘤细胞的装置。在至少一个实施例中，该装置包括用于至少一个微物体的载体; 用于施加具有磁梯度场的区域的装置，其中所述梯度场包括至少一个零点; 用于施加具有高频磁场的微物体的装置，特别是在零点的位置; 载体和区域相对运动的装置; 用于接收通过微物体的磁通量变化的装置; 用于评估接收的磁通变化并识别微物体的位置的装置; 以及用于特别地自动分析微物体的装置。

24. 发明申请

US20120021435A1 DETECTION OF LIVING, CIRCULATING, OR DISSEMINATED CELLS OR CELL CONSTITUENTS IN BLOOD OR BONE MARROW FOLLOWING FILTRATION OF BLOOD 审中-公开
标题翻译：在血液过滤中检测血液或骨髓中的生命，循环或破裂细胞或细胞因子
公开(公告)号：US20120021435A1
公开(公告)日：2012-01-26
申请号：US13187792
申请日：2011-07-21
申请人： Karsten Hiltawsky , Evamaria Stütz
发明人： Karsten Hiltawsky , Evamaria Stütz
IPC分类号： G01N21/64 , G01N21/17 , C12M1/40 , G01N33/53 , C12M1/34
CPC分类号： G01N33/56966
摘要： A method is disclosed for detecting circulating cells in a body fluid sample. In at least one embodiment, the method includes: filtering the body fluid sample through a porous membrane; transferring the porous membrane with the cells located thereon as filter residue to a cell culture vessel, wherein one surface of the cell culture vessel is coated with a first antibody which is directed to a first cell-specific marker; incubating the porous membrane in the cell culture vessel with a cell culture medium, wherein cell-specific markers released by any cells present are bound by the first antibody to produce a bound first cell-specific marker on the surface coated with the first antibody; removing the porous membrane with the cells located thereon as filter residue from the cell culture vessel; detecting the bound first cell-specific marker on the surface coated with the first antibody.
摘要翻译：公开了一种用于检测体液样品中的循环细胞的方法。在至少一个实施方案中，该方法包括：通过多孔膜过滤体液样品; 将位于其上的细胞的多孔膜作为过滤器残留物转移到细胞培养容器中，其中细胞培养容器的一个表面涂覆有针对第一细胞特异性标记物的第一抗体; 用细胞培养基培养细胞培养容器中的多孔膜，其中由任何存在的细胞释放的细胞特异性标记物被第一抗体结合，以在被第一抗体包被的表面上产生结合的第一细胞特异性标记; 用位于其上的细胞从细胞培养容器中除去多孔膜作为过滤残留物; 检测被第一抗体包被的表面上结合的第一细胞特异性标记。

25. 发明申请

US20100317960A1 THERMOTHERAPY DEVICE AND METHOD TO IMPLEMENT THERMOTHERAPY 审中-公开
标题翻译：热疗装置及实施热疗的方法
公开(公告)号：US20100317960A1
公开(公告)日：2010-12-16
申请号：US12797754
申请日：2010-06-10
申请人： Patrick Gross , Karsten Hiltawsky
发明人： Patrick Gross , Karsten Hiltawsky
IPC分类号： A61N7/02 , A61B8/14 , A61B5/055
CPC分类号： A61N7/02 , A61B8/485 , A61B18/20 , A61B2017/00084 , A61B2018/00005 , A61B2090/374 , A61B2090/378 , A61N2007/0008
摘要： A thermotherapy device has a transmitter, a receiver and a processing unit. The transmitter is designed to emit a high-energy radiation in a treatment region of a patient. The high-energy radiation exhibits a power that is suitable for thermotherapy. The receiver is designed to detect a sound signal that is generated by the treatment region depending on the high-energy radiation radiated into said treatment region. The processing unit is coupled with the transmitter) and the receiver. The processing unit automatically determines information about the treatment region depending on the detected sound signal.
摘要翻译：热疗装置具有发射器，接收器和处理单元。发射器被设计成在患者的治疗区域中发射高能辐射。高能辐射表现出适合于热疗的功效。接收器被设计成根据辐射到所述处理区域的高能辐射来检测由处理区域产生的声音信号。处理单元与发射器耦合）和接收器。处理单元根据检测到的声音信号自动确定关于治疗区域的信息。

26. 发明授权

US07740587B2 Flywheel vibrator 有权
标题翻译：飞轮振子
公开(公告)号：US07740587B2
公开(公告)日：2010-06-22
申请号：US11163912
申请日：2005-11-03
申请人： Karsten Hiltawsky
发明人： Karsten Hiltawsky
IPC分类号： A61B8/14
CPC分类号： A61B8/14 , A61B5/0051 , A61B5/6843 , A61B8/4483 , A61B8/485
摘要： The present invention is directed to an imaging tool to introduce a vibrational force into an object. The imaging tool includes a pair of flywheels that are driven by a motor in opposing rotational paths so as to introduce a harmonic mechanical excitation to the object. The imaging tool is constructed to be of handheld size so as to be suitable for ultrasound and is RF-compatible with MR scanners.
摘要翻译：本发明涉及一种将振动力引入物体的成像工具。成像工具包括一对飞轮，其由相对旋转路径中的电动机驱动，以便向对象引入谐波机械激励。成像工具被构造为具有手持尺寸以便适合于超声波，并与MR扫描仪RF兼容。

27. 发明申请

US20100076340A1 DEVICE AND METHOD TO EXTRACT MATERIAL OF A MATERIAL RESERVOIR 审中-公开
标题翻译：提取材料储存材料的装置和方法
公开(公告)号：US20100076340A1
公开(公告)日：2010-03-25
申请号：US12566009
申请日：2009-09-24
申请人： Gerald Eckstein , Karsten Hiltawsky , Heinz-Ingo Schneider , Daniel Sickert
发明人： Gerald Eckstein , Karsten Hiltawsky , Heinz-Ingo Schneider , Daniel Sickert
IPC分类号： A61B10/02 , A61B10/00
CPC分类号： A61B10/0045 , A61B10/007 , A61B10/0233 , A61B2010/008 , A61B2017/00336
摘要： A device to extract material of a material reservoir has at least one guide tube with internal space and with an inner wall surrounding the internal space; at least one sled that can implement a sled translation movement in the inner space along a longitudinal alignment of the guide tube; and at least one collection unit with collection surface to collect the material. The collection unit and the sled are coupled to one another such that the sled translation movement of the sled leads to a collection translation movement of the collection surface of the collection unit, and such that the collection surface can be inserted into the material reservoir and be withdrawn from the material reservoir. A rotation mechanism that is operated manually or automatically can be provided with which a wire, which acts as a collection device, can be displaced in vivo over a length of 1 mm to up to 2 cm within a venous cannula. The invention is used in medical technology, for example, to collect cells from a reservoir in the form of a bodily fluid.
摘要翻译：提取材料储存器材料的装置具有至少一个具有内部空间的引导管和围绕内部空间的内壁; 至少一个可以沿着导管的纵向排列在内部空间中实现滑动平移运动的滑板; 以及至少一个具有收集表面的收集单元以收集材料。收集单元和滑雪板彼此联接，使得滑板的滑轨平移运动导致收集单元的收集表面的收集平移运动，并且使得收集表面可以插入材料储存器中并且被从物料库撤出。可以提供手动或自动操作的旋转机构，其中用作收集装置的线可以在静脉插管内在1mm至高达2cm的长度内在体内移位。本发明用于医疗技术，例如以体液的形式从储存器收集细胞。

28. 发明授权

US09144418B2 Apparatus, system, and method for adaptively controlling a frame interval between ultrasound scanning frames for an ultrasound elasticity imaging scan 有权
标题翻译：用于自动控制用于超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法
公开(公告)号：US09144418B2
公开(公告)日：2015-09-29
申请号：US13399361
申请日：2012-02-17
申请人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
发明人： Feng Lin , Christopher Robert Hazard , Mirsaid Seyed-Bolorforosh , Karsten Hiltawsky , Zhe Wu
IPC分类号： A61B8/08 , G01N29/04 , G01S7/52
CPC分类号： A61B8/485 , A61B8/08 , A61B8/0858 , G01N29/041 , G01N29/043 , G01S7/52085
摘要： An apparatus, system and method for adaptively controlling a frame interval between ultrasound scanning frames of an ultrasound elasticity imaging scan. The system includes a transmitter for transmitting ultrasound beams to a subject during an ultrasound elasticity imaging scan, and a receiver for receiving ultrasound beam echoes from the subject responsive to transmitted ultrasound beams. The system also includes a processor for processing a plurality of the ultrasound beam echoes to determine a strain variation of the tissue undergoing strain, calculating a value for an ultrasound scanning frame interval adapted for imaging the tissue undergoing the determined strain variation, and setting the value of the ultrasound scanning frame interval for acquiring ultrasound elasticity images of the tissue undergoing the determined strain variation.
摘要翻译：一种用于自适应地控制超声波弹性成像扫描的超声扫描帧之间的帧间隔的装置，系统和方法。该系统包括用于在超声波弹性成像扫描期间将超声波束发送到被摄体的发射器，以及用于响应于所发送的超声波束从受检者接收超声波束回波的接收器。该系统还包括处理器，用于处理多个超声波束回波以确定经历应变的组织的应变变化，计算适于对经历所确定的应变变化的组织进行成像的超声扫描帧间隔的值，以及设定值的超声扫描帧间隔，用于获取经历所确定的应变变化的组织的超声弹性图像。

29. 发明申请

US20120290321A1 Computer implemented compensation for medical services 审中-公开
标题翻译：电脑实行医疗服务补偿
公开(公告)号：US20120290321A1
公开(公告)日：2012-11-15
申请号：US13325406
申请日：2011-12-14
申请人： Christoph Hachmöller , Karsten Hiltawsky , Sebastian Schmidt , Sabine Schäffer-Kundler
发明人： Christoph Hachmöller , Karsten Hiltawsky , Sebastian Schmidt , Sabine Schäffer-Kundler
IPC分类号： G06Q50/24
CPC分类号： G06Q50/24 , G06F19/328 , G06Q30/0214 , G16H40/20
摘要： A computer implemented method and system for compensating costs for medical services are provided. The system has at least three actors, a compensation unit, a referring computer and a service computer for executing the medical service ordered by the referring computer. After receiving a medical report as result of the medical services rendered, the referring computer is an evaluation unit for accessing quality of the medical service. Evaluation data are transmitted to the compensation unit for computation of compensation for the medical service taken into account the evaluation data for accessing quality of the medical service.
摘要翻译：提供了用于补偿医疗服务费用的计算机实现方法和系统。该系统至少有三个角色，一个补偿单元，一个推荐计算机和一个服务计算机，用于执行由引用计算机排序的医疗服务。在接收到医疗服务结果的医疗报告之后，引用计算机是用于访问医疗服务质量的评估单元。评价数据被传送到补偿单元，用于计算用于考虑用于访问医疗服务质量的评估数据的医疗服务的补偿。

30. 发明授权

US08100831B2 Direct strain estimator for measuring elastic properties of tissue 有权
标题翻译：用于测量组织弹性的直接应变估计器
公开(公告)号：US08100831B2
公开(公告)日：2012-01-24
申请号：US11562920
申请日：2006-11-22
申请人： Karsten Hiltawsky , Christopher R. Hazard , Feng Lin
发明人： Karsten Hiltawsky , Christopher R. Hazard , Feng Lin
IPC分类号： A61B8/00
CPC分类号： A61B8/08 , A61B8/485
摘要： Ultrasound data of a biological tissue is acquired in a relaxed state and a tensed state. A strain is estimated directly from the relaxed state ultrasound data and the tensed state ultrasound data by way of an imaginary part of a complex correlation function. In estimating the strain, the tensed state ultrasound data is re-stretched, and the imaginary part of the complex correlation function is calculated from this re-stretched ultrasound data and the relaxed state ultrasound data. A slope factor is also calculated, and the strain is estimated from this slope factor and the imaginary part of the complex correlation function.
摘要翻译：在松弛状态和张力状态下获取生物组织的超声数据。通过复相关函数的虚部，直接从松弛状态超声数据和张力状态超声数据估计应变。在估计应变时，张拉状态超声数据被重新拉伸，并且从该重新拉伸的超声数据和松弛状态超声数据计算复相关函数的虚部。还计算斜率因子，并根据该斜率因子和复相关函数的虚部估计应变。

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