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    • 21. 发明授权
    • Benign solvents for forming protein structures
    • 用于形成蛋白质结构的良性溶剂
    • US08318903B2
    • 2012-11-27
    • US12571043
    • 2009-09-30
    • Bin DongOlivier ArnoultGary WnekLingui Meng
    • Bin DongOlivier ArnoultGary WnekLingui Meng
    • A61K38/17C09H1/00
    • C07K1/36C07K1/145
    • A benign solvent for dissolving proteins comprises alcohol, salt and water. The ratio by volume of water to alcohol is between about ninety-nine-to-one and about one-to-ninety-nine. A salt concentration is between near zero moles per liter and the maximum salt concentration soluble in water. The amount of protein by weight as compared to the mixture of water and alcohol is between near zero percent and about 25 percent. A method for forming a protein structure from a benign solvent comprises forming a benign solvent from water, alcohol, and salt; and dissolving a protein in the benign solvent to form a protein solution. The method further comprises extracting the protein from the protein solution; and arranging the protein into a protein structure.
    • 用于溶解蛋白质的良性溶剂包括酒精,盐和水。 水与酒精的体积比为约九十九比一至约九十九分之一。 盐浓度在接近零摩尔/升和最大盐浓度溶于水。 与水和醇的混合物相比,重量比的蛋白质的量在接近零%和约25%之间。 从良性溶剂形成蛋白质结构的方法包括从水,醇和盐形成良溶剂; 并将蛋白质溶解在良溶剂中以形成蛋白质溶液。 该方法还包括从蛋白质溶液中提取蛋白质; 并将蛋白质排列成蛋白质结构。
    • 23. 发明申请
    • BENIGN SOLVENTS FOR FORMING PROTEIN STRUCTURES
    • 用于形成蛋白质结构的固体溶剂
    • US20100228011A1
    • 2010-09-09
    • US12571043
    • 2009-09-30
    • Bin DongOlivier ArnoultGary WnekLingui Meng
    • Bin DongOlivier ArnoultGary WnekLingui Meng
    • C07K1/14B01F1/00
    • C07K1/36C07K1/145
    • A benign solvent for dissolving proteins comprises alcohol, salt and water. The ratio by volume of water to alcohol is between about ninety-nine-to-one and about one-to-ninety-nine. A salt concentration is between near zero moles per liter and the maximum salt concentration soluble in water. The amount of protein by weight as compared to the mixture of water and alcohol is between near zero percent and about 25 percent. A method for forming a protein structure from a benign solvent comprises forming a benign solvent from water, alcohol, and salt; and dissolving a protein in the benign solvent to form a protein solution. The method further comprises extracting the protein from the protein solution; and arranging the protein into a protein structure.
    • 用于溶解蛋白质的良性溶剂包括酒精,盐和水。 水与酒精的体积比为约九十九比一至约九十九分之一。 盐浓度在接近零摩尔/升和最大盐浓度溶于水。 与水和醇的混合物相比,重量比的蛋白质的量在接近零%和约25%之间。 从良性溶剂形成蛋白质结构的方法包括从水,醇和盐形成良溶剂; 并将蛋白质溶解在良溶剂中以形成蛋白质溶液。 该方法还包括从蛋白质溶液中提取蛋白质; 并将蛋白质排列成蛋白质结构。
    • 28. 发明授权
    • Concurrent request handling for database transactions
    • 数据库事务的并发请求处理
    • US09430544B2
    • 2016-08-30
    • US13929478
    • 2013-06-27
    • Wen-Syan LiBin DongZheng Long WeiYongyuan Shen
    • Wen-Syan LiBin DongZheng Long WeiYongyuan Shen
    • G06F7/00G06F17/00G06F17/30
    • G06F17/30575
    • A request handler may receive transaction requests for transactions to be executed using data of a database, and may classify a first transaction request of the transaction requests as a simple transaction request, and a second transaction request of the transaction requests as a complex transaction request. A key-value store engine may execute a first transaction satisfying the first transaction request, using a key-value store of pre-calculated results determined prior to receipt of the first transaction request, and based on the data, and may update a key-value delta reflecting a change, if any, of the key-value store caused by the first transaction. A relational store engine may cause the at least one processor to execute a second transaction satisfying the second transaction request, using a relational store including a subset of the data, and may update a relational delta reflecting a change, if any, of the relational store caused by the second transaction. A synchronizer may execute a synchronization of the key-value store and the relational store, based on the key-value delta and the relational delta.
    • 请求处理程序可以接收要使用数据库的数据执行的事务的事务请求,并且可以将事务请求的第一事务请求分类为简单的事务请求,并将事务请求的第二事务请求分类为复杂事务请求。 密钥值存储引擎可以使用在接收到第一事务请求之前确定的预先计算的结果的密钥值存储,并且基于该数据来执行满足第一事务请求的第一事务,并且可以更新密钥值存储引擎, 反映由第一次交易引起的键值存储的更改(如果有的话)的值增量。 关系存储引擎可以使得至少一个处理器使用包括数据的子集的关系存储来执行满足第二事务请求的第二事务,并且可以更新反映关系存储的变化(如果有的话)的关系增量 造成第二笔交易。 基于键值增量和关系增量,同步器可以执行键值存储和关系存储的同步。