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21. 发明申请

US20120065652A1 ANASTOMOTIC DEVICES AND METHODS 有权
标题翻译：分析装置和方法
公开(公告)号：US20120065652A1
公开(公告)日：2012-03-15
申请号：US13229540
申请日：2011-09-09
申请人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
发明人： Edward H. Cully , Jeffrey B. Duncan , Karan B. Sangha
IPC分类号： A61B17/11 , A61F2/06
CPC分类号： A61M1/3655 , A61B17/08 , A61B17/11 , A61B2017/1135 , A61B2017/1139 , A61F2/064 , A61F2/07 , A61F2/89 , A61F2002/075 , A61F2002/8486 , A61F2230/0067 , A61F2230/0069
摘要： Exemplary embodiments comprise AV fistulas and other anastomotic devices for creating new or reinforcing existing side-branch vessels, and/or bridging neighboring vessels together. An exemplary embodiment may comprise a sidewall port, such as a flanged sidewall port, and/or flow frame design, such as a partially bare, flexible stent or a whisk, for purposes of creating a transmural flow. Another exemplary embodiment may comprise a compliant vessel support to aid in the transition from device to vessel and/or vessel to device, and to promote vessel dilation.
摘要翻译：示例性实施例包括用于创建新的或加强现有侧支血管，和/或将邻近血管桥接在一起的AV瘘和其它吻合装置。为了产生透壁流，示例性实施例可以包括侧壁端口，例如法兰侧壁端口和/或流动框架设计，例如部分裸露的柔性支架或者搅拌器。另一个示例性实施例可以包括顺应容器支撑件，以帮助从装置到容器和/或容器到装置的过渡，并且促进血管扩张。

22. 发明授权

US08932315B2 Systems and methods for percutaneous occlusion crossing 有权
标题翻译：用于经皮闭塞穿越的系统和方法
公开(公告)号：US08932315B2
公开(公告)日：2015-01-13
申请号：US13273111
申请日：2011-10-13
申请人： Brian R. Boland, II , Edward H. Cully , Jeffrey B. Duncan , Paul D. Goodman
发明人： Brian R. Boland, II , Edward H. Cully , Jeffrey B. Duncan , Paul D. Goodman
IPC分类号： A61B17/34 , A61B17/3207 , A61B17/22 , A61B17/00 , A61M25/00
CPC分类号： A61B17/3207 , A61B17/22 , A61B2017/00309 , A61B2017/00867 , A61B2017/22042 , A61B2017/22044 , A61B2017/22077 , A61B2017/22094 , A61B2017/22095 , A61M25/0054 , A61M25/0082 , A61M25/0194 , A61M2025/018 , A61M2025/0197
摘要： The present invention provides methods and apparatuses for crossing or bypassing total or near total occlusions of vessels through the use of elongate members and specialized catheters that include a piercing catheter, a reentry catheter, a multi-lumen, reentry catheter, and combinations thereof. A piercing catheter comprises a distal tip used to pierce an occlusion in a crossing procedure and can be configured to microdissect the occlusion or provide support for an elongate member. A reentry catheter comprises a distal side port and ramp to facilitate the reentry or perforation of a vessel wall. A multi-lumen, reentry catheter comprises a tearable lumen divider and a distal side port and ramp.
摘要翻译：本发明提供了通过使用细长构件和包括穿刺导管，再入导管，多腔再折返导管及其组合的专用导管来横穿或绕过血管的总体或近似完全闭塞的方法和装置。穿刺导管包括用于在交叉程序中刺穿闭塞的远侧末端，并且可以被配置为显微解剖闭塞或为细长构件提供支撑。再入式导管包括远端侧端口和斜面以便于容器壁的再入或穿孔。多腔重入导管包括可撕开的管腔分隔器和远端侧端口和斜坡。

23. 发明申请

US20110268781A1 DRUG ELUTING COMPOSITE 有权
公开(公告)号：US20110268781A1
公开(公告)日：2011-11-03
申请号：US13103885
申请日：2011-05-09
申请人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
发明人： Robert L. Cleek , Edward H. Cully , Jeffrey B. Duncan , Theresa A. Holland , Thomas R. McDaniel , Christine M. Scotti
IPC分类号： A61F2/01 , G06F7/60 , A61P29/00 , A61K31/573 , A61P7/02
CPC分类号： A61L31/10 , A61L29/085 , A61L29/16 , A61L31/16 , A61L2300/222 , A61L2300/608 , A61L2420/08 , A61N1/056 , A61N1/0568
摘要： The present invention relates to materials having therapeutic compositions releasably contained within the materials. The materials are configured to release therapeutic compositions at a desired rate. The present invention also relates to devices incorporating the materials.

24. 发明申请

US20110046713A1 ATRAUMATIC VASCULAR GRAFT REMOVAL SHEATH 有权
标题翻译： ATRAUMATIC VASCULAR GRAFT移除鞘
公开(公告)号：US20110046713A1
公开(公告)日：2011-02-24
申请号：US12877777
申请日：2010-09-08
申请人： EDWARD H. CULLY , Jeffrey B. Duncan
发明人： EDWARD H. CULLY , Jeffrey B. Duncan
IPC分类号： A61F2/82
CPC分类号： A61F2/97 , A61F2/06 , A61F2/07 , A61F2/95 , A61F2002/9528 , A61L31/048 , A61L31/10 , A61L31/141 , A61L31/16 , A61N1/056 , A61N2001/0578 , C08L27/12
摘要： The present invention comprises articles and methods for atraumatic removal of a chronically implanted medical device, such as a vascular graft. Specifically, the invention comprises a thin, lubricious and durable tubular cover that aids in protecting the indwelling implant during implantation while also acting as an atraumatic removal aid.
摘要翻译：本发明包括用于无损除去长期植入的医疗装置（例如血管移植物）的制品和方法。具体地，本发明包括薄的，光滑且耐用的管状盖，其有助于在植入期间保护留置植入物，同时还用作无创伤的去除辅助剂。

25. 发明申请

US20090182413A1 STENT HAVING ADJACENT ELEMENTS CONNECTED BY FLEXIBLE WEBS 有权
标题翻译：具有由柔性织物连接的相邻元件的固定元件
公开(公告)号：US20090182413A1
公开(公告)日：2009-07-16
申请号：US12350921
申请日：2009-01-08
申请人： Dustin C. Burkart , Edward H. Cully , Jeffrey B. Duncan , Cody L. Hartman , James D. Silverman
发明人： Dustin C. Burkart , Edward H. Cully , Jeffrey B. Duncan , Cody L. Hartman , James D. Silverman
IPC分类号： A61F2/06
CPC分类号： A61F2/91 , A61F2/07 , A61F2/86 , A61F2/89 , A61F2/90 , A61F2/915 , A61F2002/075 , A61F2002/826 , A61F2002/828 , A61F2002/91558
摘要： A stent incorporating flexible, preferably polymeric, connecting elements into the stent wherein these elements connect adjacent, spaced-apart stent elements. Preferably the spaced-apart adjacent stent elements are the result of forming the stent from a helically wound serpentine wire having space provided between adjacent windings. Other stent forms such as multiple, individual spaced-apart ring-shaped or interconnected stent elements may also be used. The connecting elements are typically web-shaped and result from creating slits or apertures in a covering of graft material applied to the stent and then, for example, applying heat to cause the slits or apertures to enlarge. The remaining graft material forms the interconnecting webs between the adjacent stent elements.
摘要翻译：支架将柔性，优选聚合的连接元件结合到支架中，其中这些元件连接相邻的间隔开的支架元件。优选地，间隔开的相邻支架元件是由具有设置在相邻绕组之间的空间的螺旋形缠绕蛇形线形成支架的结果。还可以使用其它支架形式，例如多个，单独间隔开的环形或互连的支架元件。连接元件通常是网状的，并且是通过在施加到支架上的移植材料的覆盖物中产生狭缝或孔，并且然后例如施加热量以使狭缝或孔径增大。剩余的移植材料形成相邻支架元件之间的互连网。

26. 发明申请

US20130090723A1 PUNCTURABLE AND RESEALABLE GRAFT 有权
标题翻译：可裁剪和可重复的格子
公开(公告)号：US20130090723A1
公开(公告)日：2013-04-11
申请号：US13644160
申请日：2012-10-03
申请人： Edward H. Cully , Jeffrey B. Duncan , Paul D. Gassier
发明人： Edward H. Cully , Jeffrey B. Duncan , Paul D. Gassier
IPC分类号： A61F2/06 , B23P11/00
CPC分类号： A61L27/507 , A61F2/07 , A61F2210/0014 , A61L2/16 , A61L27/16 , A61L27/34 , A61L27/50 , A61L2420/02 , A61L2420/08 , C08L27/18 , Y10T29/49826
摘要： Implantable grafts, particularly for arteriovenous access that may be punctured by an object such as a needle and, following removal of the object, will reseal the resulting hole to the extent of reducing fluid leakage through the graft at the puncture site to an amount less than would be typical for a conventional graft. More particularly, the grafts comprise three layers; an inner layer of implantable graft material such as ePTFE, a middle layer of self sealing elastomeric material such as silicone, and an outer layer of implantable graft material such as ePTFE. Following manufacture, the tubular form of the three-layer graft is everted to put substantially the entire wall thickness of the elastomeric material layer under circumferential compression.
摘要翻译：可植入的移植物，特别是用于可被诸如针的物体刺穿的动静脉移植物，并且在移除物体之后，将所得到的孔重新密封到在穿刺部位通过移植物的流体泄漏减少到小于对于常规移植物将是典型的。更具体地，移植物包括三层; 诸如ePTFE的可植入移植材料的内层，诸如硅树脂的自密封弹性体材料的中间层以及诸如ePTFE的可植入移植材料的外层。在制造之后，三层移植物的管状形式被旋转以将弹性体材料层的基本上整个壁厚度置于圆周压缩之下。

27. 发明申请

US20100137928A1 IMPLANTABLE LEAD 有权
标题翻译：可塑性铅
公开(公告)号：US20100137928A1
公开(公告)日：2010-06-03
申请号：US12605302
申请日：2009-10-23
申请人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61N1/05 , H01R43/16 , H01R24/04
CPC分类号： A61N1/05 , A61N1/0563 , Y10T29/49204
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.
摘要翻译：高度灵活的可植入引线，提供更好的灵活性，疲劳寿命和疲劳和耐磨性，提高了可靠性，有效的电极组织接触具有小直径和低抽提时的组织损伤风险。在一个实施例中，引线设置有除颤电极和起搏/感测电极。对于除颤/起搏引线，引线直径可以小至六法国或更小。该结构采用螺旋缠绕导体。对于并入多个独立导体的引线，许多螺旋缠绕导体以多丝状关系布置。优选地，每个导体是在其长度的大约中间部分未绝缘的导线的长度以产生电极，其中导体在大约中间的长度处折叠成一半，以形成构成平行导体的第一和第二长度段。

28. 发明授权

US08996134B2 Implantable lead 有权
标题翻译：可植入铅
公开(公告)号：US08996134B2
公开(公告)日：2015-03-31
申请号：US12615122
申请日：2009-11-09
申请人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61N1/00 , A61N1/05
CPC分类号： A61N1/0563 , A61N1/05 , Y10T29/49117
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.
摘要翻译：高度灵活的可植入引线，提供更好的灵活性，疲劳寿命和疲劳和耐磨性，提高了可靠性，有效的电极组织接触具有小直径和低抽提时的组织损伤风险。在一个实施例中，引线设置有除颤电极和起搏/感测电极。对于除颤/起搏引线，引线直径可以小至六法国或更小。该结构采用螺旋缠绕导体。对于并入多个独立导体的引线，许多螺旋缠绕的导体以多丝状关系布置。优选地，每个导体是在其长度的大约中间部分未绝缘的导线的长度以产生电极，其中导体在大约中间的长度处折叠成一半，以形成构成平行导体的第一和第二长度段。

29. 发明授权

US08364281B2 Implantable lead 有权
公开(公告)号：US08364281B2
公开(公告)日：2013-01-29
申请号：US12605302
申请日：2009-10-23
申请人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
发明人： Jeffrey B. Duncan , Aaron J. Hopkinson , Thomas R. McDaniel , Michael J. Vonesh , Jason M. Wiersdorf
IPC分类号： A61N1/00
CPC分类号： A61N1/05 , A61N1/0563 , Y10T29/49204
摘要： A highly flexible implantable lead that offers improved flexibility, fatigue life and fatigue and abrasion resistance improved reliability, effective electrode tissue contact with a small diameter and low risk of tissue damage during extraction. In one embodiment the lead is provided with both defibrillation electrodes and pacing/sensing electrodes. For defibrillation/pacing leads, the lead diameter may be as small as six French or smaller. The construction utilizes helically wound conductors. For leads incorporating multiple separate conductors, many of the helically wound conductors are arranged in a multi-filar relationship. Preferably, each conductor is a length of wire that is uninsulated at about the middle of its length to create an electrode, wherein the conductor is folded in half at about the middle of the length to create first and second length segments that constitute parallel conductors.

30. 发明授权

US5263235A Compliant drive link for tenter 失效
标题翻译：适用于拉幅机的驱动连接
公开(公告)号：US5263235A
公开(公告)日：1993-11-23
申请号：US50769
申请日：1993-04-21
申请人： Jeffrey B. Duncan , Alejandro Guevara
发明人： Jeffrey B. Duncan , Alejandro Guevara
IPC分类号： B65H23/028 , D06C3/02
CPC分类号： D06C3/02
摘要： A tentering machine having a compliant drive link allows for a considerable rate of stretch in a tentered fabric, web or film without the distortion or bowing frequently observed with the tentering machines of the prior art. The tentering machine includes two conveyor tracks adjacent to and facing one another, each conveyor track having a number of fabric edge holders slidingly directable thereabout. A fabric, web or film, grasped on opposite edges by the fabric edge holders, is conveyed thereby through the tentering machine in the space between the two conveyor tracks. Widthwise stretching occurs where the conveyor tracks of the tentering machine have sections on each side of the fabric which diverge from one another, while the two conveyor tracks may be parallel to each other on the two sides of the fabric in applications where prevention of shrinkage is of interest. The fabric edge holders on each conveyor track are run at a substantially common speed by drive chains. Elongated, spring-like compliant drive links extend from the drive chains to the fabric edge holders, but are not connected thereto. The compliant drive links allow adjacent fabric edge holders to move relative to one another, permitting a considerable rate of stretch without the distortion or bowing of the fabric, web or film observed during the use of prior-art tentering machines.

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