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21. 发明授权

US08558036B2 Dual phase catalysts system for mixed olefin hydrations 有权
标题翻译：用于混合烯烃水合物的双相催化剂体系
公开(公告)号：US08558036B2
公开(公告)日：2013-10-15
申请号：US12946014
申请日：2010-11-15
申请人： Wei Xu
发明人： Wei Xu
IPC分类号： C07C29/04
CPC分类号： B01J31/34 , B01J27/16 , B01J27/18 , B01J29/70 , B01J31/08 , C07C29/04 , C07C31/12 , C10L1/02 , C10L1/023 , C10L1/026 , C10L1/1824
摘要： Processes for producing mixed alcohols from mixed olefins and the catalyst systems for making such alcohols are provided. Additionally, processes for producing fuel compositions having mixed alcohols prepared from mixed olefins are also provided as embodiments of the present invention. The catalyst systems include a dual phase catalyst system that includes a water soluble acid catalyst and a solid acid catalyst.
摘要翻译：提供了从混合烯烃制备混合醇的方法和制备这些醇的催化剂体系。此外，作为本发明的实施方案，也提供了由混合烯烃制备具有混合醇的燃料组合物的方法。催化剂体系包括双相催化剂体系，其包括水溶性酸催化剂和固体酸催化剂。

22. 发明申请

US20130104135A1 DATA CENTER OPERATION 有权
标题翻译：数据中心操作
公开(公告)号：US20130104135A1
公开(公告)日：2013-04-25
申请号：US13643595
申请日：2010-04-20
申请人： Bin Cai , Zhe Xiang , Wei Xu , Bo Yang , Qi Yu
发明人： Bin Cai , Zhe Xiang , Wei Xu , Bo Yang , Qi Yu
IPC分类号： G06F9/48
CPC分类号： G06F9/52 , G06F8/71 , G06F9/4812 , G06F9/4843 , G06F9/5005 , G06F9/5066 , G06F16/00 , G06F16/182 , G06F16/1873 , G06F17/40
摘要： In response to a map task distributed by a job tracker, a map task tracker executes the map task to generate a map output including version information. The map task tracker stores the generated map outputs. The map task tracker informs the job tracker of related information of the map output. In response to a reduce task distributed by the job tracker, the reduce task tracker acquires the map outputs for key names including given version information from the map task trackers, wherein the acquired map outputs include the map outputs with the given version information and historical map outputs with the version information prior to the given version information. The reduce task tracker executes the reduce task on the acquired map outputs.
摘要翻译：响应于作业跟踪器分发的地图任务，地图任务跟踪器执行地图任务以生成包括版本信息的地图输出。地图任务跟踪器存储生成的地图输出。地图任务跟踪器通知作业跟踪器地图输出的相关信息。为了响应作业跟踪器分发的减少任务，减少任务跟踪器从地图任务跟踪器获取包括给定版本信息的密钥名称的地图输出，其中所获取的地图输出包括具有给定版本信息和历史地图的地图输出输出与给定版本信息之前的版本信息。减少任务跟踪器对所获取的地图输出执行缩减任务。

23. 发明申请

US20120306120A1 Compression Programming of Shape Memory Polymers Below the Glass Transition Temperature 审中-公开
标题翻译：形状记忆聚合物的压缩编程低于玻璃化转变温度
公开(公告)号：US20120306120A1
公开(公告)日：2012-12-06
申请号：US13464461
申请日：2012-05-04
申请人： Guoqiang Li , Wei Xu
发明人： Guoqiang Li , Wei Xu
IPC分类号： B29C59/02
CPC分类号： C08L25/08 , C08K3/40 , C08L2201/12 , C08L2203/02 , C08L2205/16 , C08L2312/00 , C08L67/02
摘要： Compression programming of a shape memory polymer without the requirement of added heat, wherein the programming occurs at a temperature below the glass transition of the shape memory polymer. The shape memory polymer can be either a thermoset or a thermoplastic shape memory polymer.
摘要翻译：形状记忆聚合物的压缩编程，而不需要加热，其中编程发生在形状记忆聚合物的玻璃化转变温度以下。形状记忆聚合物可以是热固性或热塑性形状记忆聚合物。

24. 发明授权

US08271450B2 Monitoring a data structure in a virtual machine and determining if memory pages containing the data structure are swapped into or out of guest physical memory 有权
标题翻译：监视虚拟机中的数据结构，并确定包含数据结构的内存页是否与客户物理内存进行交换
公开(公告)号：US08271450B2
公开(公告)日：2012-09-18
申请号：US12572158
申请日：2009-10-01
申请人： Oded Horovitz , Ophir Rachman , Wei Xu , Adrian Drzewiecki , Xiaoxin Chen
发明人： Oded Horovitz , Ophir Rachman , Wei Xu , Adrian Drzewiecki , Xiaoxin Chen
IPC分类号： G06F7/00 , G06F17/00
CPC分类号： G06F11/301 , G06F11/3089 , G06F12/10 , G06F21/53 , G06F21/566 , G06F2009/45583 , G06F2009/45587 , G06F2221/2101
摘要： A method for monitoring a data structure maintained by guest software within a virtual machine is disclosed. Changes to the contents of the data structure are determined, such as by placing write traces on the memory pages containing the data structure. Also, the method involves determining when memory pages containing the data structure are swapped into and/or out of guest physical memory by the guest software, such as by placing write traces on the memory pages containing the guest page table and detecting changes to the present bit of page table entries involved in mapping virtual addresses for the data structure. Information about the contents of the data structure is retained while memory pages containing the data structure are swapped out of guest physical memory.
摘要翻译：公开了一种用于监视由虚拟机内的客户软件维护的数据结构的方法。确定对数据结构内容的更改，例如通过在包含数据结构的内存页上放置写入轨迹。此外，该方法包括确定包含数据结构的存储器页面何时由客户软件交换到和/或离开客户机物理存储器，例如通过在包含访客页面表的存储器页面上放置写入跟踪并检测对当前的变化参与映射数据结构的虚拟地址的页表项的位。关于数据结构的内容的信息被保留，而包含数据结构的存储器页面被从客体物理存储器换出。

25. 发明申请

US20120184523A1 C-Met Modulators and Method of Use 审中-公开
公开(公告)号：US20120184523A1
公开(公告)日：2012-07-19
申请号：US13427093
申请日：2012-03-22
申请人： Lynne Canne Bannen , Diva Sze-Ming Chan , Jeff Chen , Lisa Esther Dalrymple , Timothy Patrick Forsyth , Tai Phat Huynh , Vasu Jammalamadaka , Richard George Khoury , James William Leahy , Morrison B. Mac , Grace Mann , Larry W. Mann , John M. Nuss , Jason Jevious Parks , Craig Stacy Takbuchi , Yong Wang , Wei Xu
发明人： Lynne Canne Bannen , Diva Sze-Ming Chan , Jeff Chen , Lisa Esther Dalrymple , Timothy Patrick Forsyth , Tai Phat Huynh , Vasu Jammalamadaka , Richard George Khoury , James William Leahy , Morrison B. Mac , Grace Mann , Larry W. Mann , John M. Nuss , Jason Jevious Parks , Craig Stacy Takbuchi , Yong Wang , Wei Xu
IPC分类号： A61K31/4709 , A61K31/517 , C07D215/233 , C07D401/12 , A61K31/47 , C07D239/94 , C07D417/12 , C07D401/10 , C07D413/12 , A61K31/5377 , C07D215/46 , C07D417/14 , A61K31/501 , A61K31/496 , A61K31/513 , C12N9/99 , C12Q1/48 , C12Q1/66 , A61P35/00 , A61P29/00 , A61P37/00 , A61P37/06 , A61P25/00 , A61P17/06 , A61P9/00 , A61P9/10 , A61P1/00 , A61P19/02 , A61P27/02 , C07D403/10
CPC分类号： C07D215/233 , A61K31/47 , A61K31/4709 , A61K31/4725 , A61K31/496 , A61K31/501 , A61K31/505 , A61K31/506 , A61K31/517 , A61K31/5377 , C07D215/22 , C07D215/36 , C07D215/38 , C07D215/46 , C07D239/88 , C07D239/94 , C07D295/15 , C07D401/12 , C07D401/14 , C07D403/12 , C07D405/14 , C07D413/12 , C07D413/14 , C07D417/12 , C12Q1/485 , G01N2500/04 , Y02A50/393
摘要： The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. More specifically, the invention provides quinazolines and quinolines which inhibit, regulate, and/or modulate kinase receptor, particularly c-Met, KDF, c-Kit, flt-3 and flt-4, signal transduction pathways related to the changes in cellular activities as mentioned above, compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions. The present invention also provides methods for making compounds as mentioned above, and compositions which contain these compounds.

26. 发明申请

US20120059011A1 PHARMACEUTICAL COMPOSITIONS OF COMBINATIONS OF DIPEPTIDYL PEPTIDASE-4 INHIBITORS WITH PIOGLITAZONE 审中-公开
标题翻译： DIPEPTIDYL PEPTIDASE-4抑制剂与PIOGLITAZONE的组合药物组合物
公开(公告)号：US20120059011A1
公开(公告)日：2012-03-08
申请号：US13319718
申请日：2010-06-04
申请人： Nicholas Birringer , Christopher T. John , Adam Procopio , Bhagwant Rege , Lawrence A. Rosen , Sutthilug Sotthivirat , Wei Xu
发明人： Nicholas Birringer , Christopher T. John , Adam Procopio , Bhagwant Rege , Lawrence A. Rosen , Sutthilug Sotthivirat , Wei Xu
IPC分类号： A61K31/4439 , A61K31/513 , A61P3/10 , A61K31/4985
CPC分类号： A61K45/06 , A61K31/44 , A61K31/4439 , A61K2300/00
摘要： This invention relates to pharmaceutical compositions comprising fixed-dose combinations of a dipeptidyl peptidase-4 inhibitor and pioglitazone, methods of preparing such pharmaceutical compositions, and methods of treating Type 2 diabetes with such pharmaceutical compositions.
摘要翻译：本发明涉及包含二肽基肽酶-4抑制剂和吡格列酮的固定剂量组合的药物组合物，制备这种药物组合物的方法，以及用这种药物组合物治疗2型糖尿病的方法。

27. 发明授权

US08013156B2 Tie-2 modulators and methods of use 失效
标题翻译： Tie-2调制剂和使用方法
公开(公告)号：US08013156B2
公开(公告)日：2011-09-06
申请号：US10549300
申请日：2004-03-19
申请人： Lynne Canne Bannen , S. David Brown , Wei Cheng , Vasu Jammalamadaka , John M. Nuss , Morrison B. Mac , Jason Jevious Parks , Matthew A. Williams , Wei Xu , Atwood Kim Cheung , Lisa Esther Dalrymple , Sergey Epshteyn , Mohamed Abdulkader Ibrahim , James William Leahy , Gary Lee Lewis , Robin Tammie Noguchi , Larry Wayne Mann , Brian Hugh Ridgway , Joan C. Sangalang , Kevin Luke Schnepp , Xian Shi , Richard George Khoury
发明人： Lynne Canne Bannen , S. David Brown , Wei Cheng , Vasu Jammalamadaka , John M. Nuss , Morrison B. Mac , Jason Jevious Parks , Matthew A. Williams , Wei Xu , Atwood Kim Cheung , Lisa Esther Dalrymple , Sergey Epshteyn , Mohamed Abdulkader Ibrahim , James William Leahy , Gary Lee Lewis , Robin Tammie Noguchi , Larry Wayne Mann , Brian Hugh Ridgway , Joan C. Sangalang , Kevin Luke Schnepp , Xian Shi , Richard George Khoury
IPC分类号： C07D401/14 , C07D403/14 , A61K31/4425 , A61K31/495 , A61K31/506 , A61P19/02 , A61P35/00
CPC分类号： A61K31/496 , C07D213/75 , C07D239/42 , C07D401/12 , C07D401/14 , C07D403/12 , C07D417/12 , C07D417/14
摘要： The present invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration and chemoinvasion. Compounds of the invention inhibit, regulate and/or modulate kinases, particularly Tie-2. Methods of using the compounds and pharmaceutical compositions thereof to treat kinase-dependent diseases and conditions are also an aspect of the invention.
摘要翻译：本发明提供调节蛋白激酶酶活性以调节细胞活性如增殖，分化，程序性细胞死亡，迁移和化学侵蚀的化合物。本发明的化合物抑制，调节和/或调节激酶，特别是Tie-2。使用化合物及其药物组合物治疗激酶依赖性疾病和病症的方法也是本发明的一个方面。

28. 发明授权

US07994172B2 [1H-pyrazolo[3, 4-D]pyrimidin-4-yl]-piperidine or -piperazine compounds as serine-theoronine kinase modulators (P70s6k, Atk1 and Atk2) for the treatment of immunological, inflammatory and proliferative diseases 失效
标题翻译： [1H-吡唑并[3,4-D]嘧啶-4-基] - 哌啶或哌嗪化合物，作为用于治疗免疫学，炎症和增殖性疾病的丝氨酸 - 氨氮激酶调节剂（P70s6k，Atk1和Atk2）
公开(公告)号：US07994172B2
公开(公告)日：2011-08-09
申请号：US11722291
申请日：2005-12-27
申请人： Ken Rice , Erick Wang Co , Moon Hwan Kim , Lynn Canne Bannen , Joerg Bussenius , Donna Tra Le , Amy Lew Tsuhako , John Nuss , Yong Wang , Wei Xu , Rhett Ronald Klein
发明人： Ken Rice , Erick Wang Co , Moon Hwan Kim , Lynn Canne Bannen , Joerg Bussenius , Donna Tra Le , Amy Lew Tsuhako , John Nuss , Yong Wang , Wei Xu , Rhett Ronald Klein
IPC分类号： C07D487/04 , A61K31/519 , A61P35/00
CPC分类号： C07D487/04
摘要： The invention provides compounds of formula (I) and methods for inhibition of kinases, more specifically p70S6 kinases, and more preferably p70S6, Akt-1 and Akt-2 kinases. The invention provides compounds for modulating protein kinase enzymatic activity for modulating cellular activities such as proliferation, differentiation, programmed cell death, migration, chemoinvasion and metabolism. Compounds of the invention inhibit, regulate and/or modulate kinase receptor signal transduction pathways related to the changes in cellular activities as mentioned above, and the invention includes compositions which contain these compounds, and methods of using them to treat kinase-dependent diseases and conditions.
摘要翻译：本发明提供式（I）化合物和抑制激酶，更特别是p70S6激酶，更优选p70S6，Akt-1和Akt-2激酶的方法。本发明提供用于调节蛋白激酶酶活性以调节细胞活性如增殖，分化，程序性细胞死亡，迁移，化学侵袭和代谢的化合物。本发明的化合物抑制，调节和/或调节与上述细胞活性变化相关的激酶受体信号转导途径，本发明包括含有这些化合物的组合物，以及使用它们治疗激酶依赖性疾病和病症的方法。

29. 发明申请

US20100249071A1 Modulators of S1P and Methods of Making And Using 审中-公开
标题翻译： S1P的调制器和制作和使用方法
公开(公告)号：US20100249071A1
公开(公告)日：2010-09-30
申请号：US12731997
申请日：2010-03-25
申请人： Lynne Canne Bannen , Diva Sze-Ming Chan , Morrison B. Mac , Stephanie Ng , John M. Nuss , Yong Wang , Wei Xu
发明人： Lynne Canne Bannen , Diva Sze-Ming Chan , Morrison B. Mac , Stephanie Ng , John M. Nuss , Yong Wang , Wei Xu
IPC分类号： A61K31/4439 , C07D417/04 , C07D513/04 , A61K31/433 , C07D285/12 , C07D417/12 , C07F9/09 , A61K31/675 , C07D417/14 , A61K31/506 , A61P37/06 , A61P17/06 , A61P19/02 , A61P29/00 , A61P19/10
CPC分类号： C07D285/12 , C07D417/04 , C07D417/12 , C07D513/04
摘要： The invention is directed to Compounds of Formula I: as well as methods of making and using the compounds.
摘要翻译：本发明涉及式I化合物：以及制备和使用该化合物的方法。

30. 发明申请

US20100187286A1 Surgical Stapling Head Assembly with a Rotary Cutter 有权
标题翻译：带旋转切割机的手术装订头组件
公开(公告)号：US20100187286A1
公开(公告)日：2010-07-29
申请号：US12666964
申请日：2008-06-26
申请人： Wangdong Chen , Wei Xu , Shouye Xie
发明人： Wangdong Chen , Wei Xu , Shouye Xie
IPC分类号： A61B17/068
CPC分类号： A61B17/072 , A61B17/115 , A61B17/32053 , A61B2017/07285
摘要： http://www.wipo/int/pctdb/images/PCT-IMAGES/31122008/CN2008001226_31122008_gz_en.×4-b.jpgA surgical stapling head assembly with a rotary cutter comprises a casing (101), an annular cutter (103), a staple driver (102) and a staple holder. Said staple driver (102) is connected with the annular cutter (103) by a bearing structure (109) with guiding projections (115a, 115b, 115c) disposed thereon, on the outer wall of the anti-expansion tube (104) or the inner wall of the casing (101) is molded with a metal cylinder member (105), on which is provided with a forward helix track (106) and a backward track (107) independent and communicated with each other, the guiding projections (115a, 115b, 115c) engaging with the two guiding tracks (106, 107) to guide the annular cutter (103) to forward in way of helix.
摘要翻译：具有旋转切割器的外科缝合头组件包括壳体（101），环形切割器（103），圆形切割器（103），圆形切割器（103），订书钉驱动器（102）和订书钉保持器。所述订书钉驱动器（102）通过轴承结构（109）与所述环形切割器（103）连接，所述轴承结构具有设置在其上的引导突起（115a，115b，115c），位于所述防膨胀管（104）的外壁上或壳体（101）的内壁用金属圆柱体（105）模制，在其上设置有独立且彼此连通的前向螺旋轨道（106）和后向轨道（107），引导突起（115a），115b，115c）与两个引导轨道（106,107）接合，以引导环形刀具（103）以螺旋方式前进。

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