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21. 发明授权

US08067936B2 Frequency swept excitation for magnetic resonance 有权
标题翻译：用于磁共振的频率扫描激励
公开(公告)号：US08067936B2
公开(公告)日：2011-11-29
申请号：US12850508
申请日：2010-08-04
申请人： Michael G. Garwood , Djaudat S. Idiyatullin , Curtis A. Corum , Steen Moeller
发明人： Michael G. Garwood , Djaudat S. Idiyatullin , Curtis A. Corum , Steen Moeller
IPC分类号： G01V3/00
CPC分类号： G01N24/10 , G01N24/081 , G01R33/441 , G01R33/446 , G01R33/4616 , G01R33/4816 , G01R33/54
摘要： A method of magnetic resonance is provided that uses a frequency swept excitation wherein the acquired signal is a time domain signal is provided. In one embodiment, the method comprises, applying a sweeping frequency excitation and acquiring a time domain signal. The sweeping frequency excitation has a duration and is configured to sequentially excite isochromats having different resonant frequencies. Acquisition of the time domain signal is done during the duration of the sweeping frequency excitation. The time domain signal is based on evolution of the isochromats.
摘要翻译：提供了一种磁共振的方法，其使用频率扫描激励，其中提供所获取的信号是时域信号。在一个实施例中，该方法包括：施加扫频激励并获取时域信号。扫频频率激励具有持续时间并且被配置为顺序地激发具有不同谐振频率的异色素。在扫描频率激励的持续时间内完成时域信号的采集。时域信号是基于异色素的进化。

22. 发明授权

US09841480B2 Localization of magnetic particles by means of swift-MRI 有权
公开(公告)号：US09841480B2
公开(公告)日：2017-12-12
申请号：US13262397
申请日：2010-04-01
申请人： Curtis A. Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
发明人： Curtis A. Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
IPC分类号： G01R33/48 , G01R33/32 , G01R33/56
CPC分类号： G01R33/5601 , G01R33/4816
摘要： Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component.

23. 发明授权

US08519707B2 Pulse gap cycling for improved swift 有权
公开(公告)号：US08519707B2
公开(公告)日：2013-08-27
申请号：US12752668
申请日：2010-04-01
申请人： Curtis A Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
发明人： Curtis A Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
IPC分类号： G01V3/00
CPC分类号： G01R33/54 , G01R33/4641 , G01R33/4816 , G01R33/4824 , G01R33/565 , G01R33/56509
摘要： A magnetic resonance image is produced by shifting a gap during acquisition of spin data for a specimen. The spin data is generated by a gapped excitation sequence.

24. 发明申请

US20120092010A1 LOCALISATION OF MAGNETIC PARTICLES BY MEANS OF SWIFT-MRI 有权
标题翻译：通过SWIFT-MRI定位磁性颗粒
公开(公告)号：US20120092010A1
公开(公告)日：2012-04-19
申请号：US13262397
申请日：2010-04-01
申请人： Curtis A. Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
发明人： Curtis A. Corum , Djaudat S. Idiyatullin , Steen Moeller , Michael G. Garwood
IPC分类号： G01R33/48 , G01R33/32
CPC分类号： G01R33/5601 , G01R33/4816
摘要： Positive contrast localization of magnetic (e.g. superparamagnetic) particles in vivo or in vitro by means of SWIFT-MRI using the imaginary component of MR image data in combination with an anatomic reference image derived from the real or magnitude component.
摘要翻译：使用MR图像数据的虚部和结合从实数或幅度分量导出的解剖参考图像，通过SWIFT-MRI在体内或体外的磁性（例如超顺磁性）颗粒的正对比定位。

25. 发明申请

US20100253340A1 ADIABATIC MAGNETIZATION PREPARATION FOR B1 AND B0 INSENSITIVE HIGH CONTRAST MRI 有权
标题翻译： B1和B0敏感性高对比度MRI的ADIABATIC MAGNETIZATION准备
公开(公告)号：US20100253340A1
公开(公告)日：2010-10-07
申请号：US12752633
申请日：2010-04-01
申请人： Curtis A. Corum , Steen Moeller , Djaudat S. Idiyatullin , Michael G. Garwood
发明人： Curtis A. Corum , Steen Moeller , Djaudat S. Idiyatullin , Michael G. Garwood
IPC分类号： G01R33/48
CPC分类号： G01R33/4816
摘要： A magnetic resonance image is produced by radial imaging using one or more preparatory pulses. The magnetic preparation pulse can include one or more adiabatic pulses.
摘要翻译：通过使用一个或多个准备脉冲的径向成像产生磁共振图像。磁性制备脉冲可以包括一个或多个绝热脉冲。

26. 发明授权

US07932719B2 Magnetic resonance contrast using fictitious field relaxation 有权
标题翻译：磁共振对比使用虚拟场弛豫
公开(公告)号：US07932719B2
公开(公告)日：2011-04-26
申请号：US12731936
申请日：2010-03-25
申请人： Timo Liimatainen , Michael G. Garwood , Dennis J. Sorce , Shalom Michaeli
发明人： Timo Liimatainen , Michael G. Garwood , Dennis J. Sorce , Shalom Michaeli
IPC分类号： G01V3/00
CPC分类号： A61B5/055 , G01R33/50
摘要： A system includes a signal generator and a processor. The signal generator is configured to couple with a magnetic resonance transmitter coil. The processor is configured to execute instructions to control the signal generator. The instructions include forming a sequence of waveforms. The sequence is configured to generate spin relaxation in a fictitious field in a third rotating frame of reference based on at least one magnetic field component that arises based on an effective field in a second rotating frame of reference. The third rotating frame of reference is of a higher order than the second rotating frame of reference and the second rotating frame of reference is of a higher order than the first rotating frame of reference.
摘要翻译：系统包括信号发生器和处理器。信号发生器被配置为与磁共振发射器线圈耦合。处理器被配置为执行指令来控制信号发生器。指令包括形成一系列波形。该序列被配置为基于基于第二旋转参考系中的有效场而产生的至少一个磁场分量在第三旋转参考系中的虚拟场中产生自旋弛豫。第三旋转参考系具有比第二旋转参考系更高的顺序，并且第二旋转参考系的参考点比第一旋转参考系高。

27. 发明授权

US07279899B2 Contrast from rotating frame relaxation by adiabatic pulses 有权
标题翻译：对比由绝热脉冲旋转框架松弛
公开(公告)号：US07279899B2
公开(公告)日：2007-10-09
申请号：US11244815
申请日：2005-10-06
申请人： Shalom Michaeli , Michael G. Garwood , Kamil Ugurbil , Dennis J. Sorce
发明人： Shalom Michaeli , Michael G. Garwood , Kamil Ugurbil , Dennis J. Sorce
IPC分类号： G01V3/00
CPC分类号： G01R33/446 , G01R33/50
摘要： This document discusses, among other things, a system and method for modulating transverse and longitudinal relaxation time contrast in a rotating frame based on a train of radio frequency pulses.
摘要翻译：本文件尤其涉及一种用于基于一串射频脉冲调制旋转帧中的横向和纵向弛豫时间对比度的系统和方法。

28. 发明申请

US20180085184A1 IMAGING FIDUCIAL MARKERS AND METHODS 审中-公开
公开(公告)号：US20180085184A1
公开(公告)日：2018-03-29
申请号：US15828021
申请日：2017-11-30
申请人： Patrick Bolan , Michael G. Garwood , Michael T. Nelson , Daniel A. Halpern
发明人： Patrick Bolan , Michael G. Garwood , Michael T. Nelson , Daniel A. Halpern
IPC分类号： A61B17/34 , A61K49/00 , A61K49/04 , A61K49/18 , A61K49/22 , A61B8/08 , A61M31/00 , G01R33/48 , G01R33/56 , H01F41/02
CPC分类号： A61B90/39 , A61B8/481 , A61B17/3468 , A61B2090/3908 , A61B2090/3925 , A61B2090/3933 , A61B2090/3954 , A61B2090/3958 , A61B2090/3966 , A61B2090/397 , A61B2090/3995 , A61K49/0002 , A61K49/0447 , A61K49/18 , A61K49/223 , A61M31/002 , A61M31/005 , A61M37/00 , G01R33/4812 , G01R33/4814 , G01R33/5601 , G01R33/58 , H01F41/02 , H01F41/0253 , Y10T29/49075 , Y10T29/49888 , Y10T29/4998 , Y10T29/49982
摘要： An implantable tissue marker incorporates a contrast agent sealed within a chamber in a container formed from a solid material. The contrast agent is selected to produce a change, such as an increase, in signal intensity under magnetic resonance imaging (MRI). An additional contrast agent may also be sealed within the chamber to provide visibility under another imaging modality, such as computed tomographic (CT) imaging or ultrasound imaging.

29. 发明申请

US20140218028A1 BEAM STEERING WITH RESONANCE ALONG A TRAJECTORY 有权
标题翻译：光束转向与谐波在轨道
公开(公告)号：US20140218028A1
公开(公告)日：2014-08-07
申请号：US14174368
申请日：2014-02-06
申请人： Angela Lynn Styczynski Snyder , Carl J. Snyder , Michael G. Garwood , J. Thomas Vaughan, JR.
发明人： Angela Lynn Styczynski Snyder , Carl J. Snyder , Michael G. Garwood , J. Thomas Vaughan, JR.
IPC分类号： G01R33/44 , G01R33/32
CPC分类号： G01R33/4816 , G01R33/4833 , G01R33/56536 , G01R33/56563 , G01R33/5659
摘要： A method for generating a magnetic resonance image includes configuring a magnetic field to correspond to a trajectory within a region of interest. The method includes applying RF excitation to spatially control a region of magnetic resonance corresponding to the trajectory. The method includes modulating the magnetic field coincident with the spatially controlled region of magnetic resonance. The method includes acquiring data corresponding to the region of magnetic resonance and generating an image based on the data.
摘要翻译：用于产生磁共振图像的方法包括配置磁场以对应于感兴趣区域内的轨迹。该方法包括应用RF激励以空间控制对应于轨迹的磁共振区域。该方法包括调制与磁共振的空间受控区域一致的磁场。该方法包括获取对应于磁共振区域的数据并基于该数据生成图像。

30. 发明授权

US06650116B2 Method and system for NMR using adiabatic RF pulses producing spatially quadratic phase 有权
标题翻译： NMR的方法和系统使用绝热RF脉冲产生空间二次相
公开(公告)号：US06650116B2
公开(公告)日：2003-11-18
申请号：US09961502
申请日：2001-09-24
申请人： Michael G. Garwood , Kamil Ugurbil , Lance DelaBarre , Patrick Bolan
发明人： Michael G. Garwood , Kamil Ugurbil , Lance DelaBarre , Patrick Bolan
IPC分类号： G01V300
CPC分类号： G01R33/4616 , G01R33/483
摘要： A method and system for performing MRI and NMR spectroscopy that improves the dynamic range of the received signal by using adiabatic RF pulses for spin excitation rather than for spin inversion. The preferred adiabatic RF excitation produces a spatially varying phase across the slab, and a sharp slab profile. The phase variation is divided up by a phase-encoding gradient into voxels having a phase variation that is negligible over the width of the voxel. The phase variation in the slab-select direction is, on the whole, large enough that the peak amplitude of the received signal is reduced and the signal width broadened. This reduces the dynamic range required of the analog to digital converter used in a NMR system. A NMR system suitable for carrying out the methods of the invention is also disclosed.
摘要翻译：用于执行MRI和NMR光谱的方法和系统，其通过使用绝热RF脉冲进行自旋激励而不是自旋反转来改善接收信号的动态范围。优选的绝热RF激发产生横跨板坯的空间变化的相位，并且产生锋利的板坯轮廓。相位变化通过相位编码梯度被划分成具有在体素的宽度上可忽略的相位变化的体素。平板选择方向的相位变化总体上足够大，使得接收信号的峰值幅度减小并且信号宽度变宽。这降低了在NMR系统中使用的模数转换器所需的动态范围。还公开了适用于实施本发明方法的NMR系统。

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